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Lista de obras de Hakon Leffler

1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors

artículo científico publicado en 2010

3-(1,2,3-Triazol-1-yl)-1-thio-galactosides as small, efficient, and hydrolytically stable inhibitors of galectin-3.

artículo científico publicado en 2005

3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-sites for High-Affinity and High-Selectivity Inhibition of Galectin-3

scientific article published on 12 December 2019

A Galactoside-Binding Protein Tricked into Binding Unnatural Pyranose Derivatives: 3-Deoxy-3-Methyl-Gulosides Selectively Inhibit Galectin-1

scientific article published on 02 August 2019

A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model

artículo científico publicado en 2016

A novel sulfoglycosphingolipid of mouse small intestine, IV3-sulfogangliotetraosylceramide, demonstrated by negative ion fast atom bombardment mass spectrometry

scientific article published on 01 January 1986

A sialoglycoprotein complex linked to the microvillus cytoskeleton acts as a receptor for pilus (AF/R1) mediated adhesion of enteropathogenic Escherichia coli (RDEC-1) in rabbit small intestine ⬇️

artículo científico publicado el 1 de noviembre de 1991

Activation of the neutrophil nicotinamide adenine dinucleotide phosphate oxidase by galectin-1.

artículo científico publicado en 2002

Adhesion of Escherichia coli in Urinary Tract Infection ⬇️

artículo científico publicado el 1 de enero de 1981

Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface

artículo científico

An orally active galectin-3 antagonist inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade

scientific article published on 23 January 2019

Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells. Evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway

artículo científico publicado en 1993

Apical sorting by galectin-3-dependent glycoprotein clustering

artículo científico publicado en 2007

Arene-anion based arginine-binding motif on a galactose scaffold: structure-activity relationships of interactions with arginine-rich galectins

artículo científico publicado en 2011

Arginine binding motifs: design and synthesis of galactose-derived arginine tweezers as galectin-3 inhibitors

artículo científico publicado en 2008

Aspects on structure and function of pili on uropathogenic Escherichia coli.

artículo científico publicado en 1983

Assignment of 1H, 15N and 13C resonances of the carbohydrate recognition domain of human galectin-3

artículo científico publicado en 2001

Attachment of Streptococcus pneumoniae to human pharyngeal epithelial cells in vitro--mechanism of binding

scientific article published on 01 June 1984

Bacterial adherence--a pathogenetic mechanism in urinary tract infections caused by Escherichia coli

artículo científico publicado el 1 de enero de 1983

Binding Specificity of Piliated Strains of Escherichia coli and Salmonella typhimurium to Epithelial Cells, Saccharomyces cerevisiae Cells, and Erythrocytes ⬇️

artículo científico publicado el 1 de mayo de 1981

Binding specificities of wild-type and cloned Escherichia coli strains that recognize globo-A.

artículo científico publicado en 1989

Binding to galactose alpha 1----4galactose beta-containing receptors as potential diagnostic tool in urinary tract infection.

artículo científico publicado en 1987

Blood Group Type Glycosphingolipids from the Small Intestine of Different Animals Analysed by Mass Spectrometry and Thin-Layer Chromatography. A Note on Species Diversity12 ⬇️

artículo científico publicado el 1 de septiembre de 1981

Blood group non-secretors have an increased inflammatory response to urinary tract infection.

artículo científico publicado en 1992

C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: efficient lectin inhibition through double arginine-arene interactions

artículo científico publicado en 2005

Characterization of cerebroside (monoglycosylceramide) from the sea anemone, Metridium senile. Identification of the major long-chain base as an unusual dienic base with a methyl branch at a double bond

artículo científico publicado en 1979

Characterization of the forssman glycolipid hapten of horse kidney by mass spectrometry.

artículo científico publicado en 1974

Chemical and clinical studies on the interaction of Escherichia coli with host glycolipid receptors in urinary tract infection

artículo científico publicado en 1982

Chemical characterization of penta-, hexa-, hepta-, octa-, and nonaglycosylceramides of rat small intestine having a globoside-like terminus

artículo científico publicado en 1982

Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells

artículo científico publicado en 2005

Conformational differences in liganded and unliganded states of Galectin-3.

artículo científico publicado en 2003

Correlation of P Blood Group, Vesicoureteral Reflux, and Bacterial Attachment in Patients with Recurrent Pyelonephritis ⬇️

artículo científico publicado el 19 de mayo de 1983

Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins

artículo científico publicado en 1995

Crystallization and preliminary X-ray diffraction analysis of the human dimeric S-Lac lectin (L-14-II).

artículo científico publicado en 1993

Demonstration of complexity of the glycosphingolipid fraction of rat small intestine

artículo científico publicado en 1980

Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins

artículo científico publicado en 2007

Design and synthesis of galectin inhibitors

scientific article published on 01 January 2003

Designing interactions by control of protein-ligand complex conformation: tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions.

artículo científico publicado en 2017

Different affinity of galectins for human serum glycoproteins: galectin-3 binds many protease inhibitors and acute phase proteins

artículo científico publicado en 2008

Different binding specificities of P. mirabilis compared to E. coli

artículo científico publicado en 1982

Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease

scientific article published on 17 January 2012

Differential roles of galectin-1 and galectin-3 in regulating leukocyte viability and cytokine secretion

artículo científico publicado en 2008

Distance mapping of protein-binding sites using spin-labeled oligosaccharide ligands

artículo científico publicado en 2001

Double affinity amplification of galectin-ligand interactions through arginine-arene interactions: synthetic, thermodynamic, and computational studies with aromatic diamido thiodigalactosides

artículo científico publicado en 2008

Efficient and expedient two-step pyranose-retaining fluorescein conjugation of complex reducing oligosaccharides: galectin oligosaccharide specificity studies in a fluorescence polarization assay.

artículo científico publicado en 2003

Enhancement of bound-state residual dipolar couplings: conformational analysis of lactose bound to Galectin-3.

artículo científico

Epimers Switch Galectin-9 Domain Selectivity: 3N-Aryl Galactosides Bind the C-Terminal and Gulosides Bind the N-Terminal

scientific article published on 04 December 2019

Erratum: Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3

artículo científico publicado en 2016

Extracellular and intracellular small-molecule galectin-3 inhibitors

Fecal excretion of intestinal glycosphingolipids by newborns and young children

scientific article published on 01 April 1987

Fluorescence polarization as an analytical tool to evaluate galectin-ligand interactions

artículo científico publicado en 2004

Fluorescence polarization to study galectin-ligand interactions

artículo científico publicado en 2003

Fluorescent leukotriene B4: potential applications

artículo científico publicado en 2005

Fragment-based development of triazole-substituted O-galactosyl aldoximes with fragment-induced affinity and selectivity for galectin-3.

artículo científico publicado en 2009

Gal-3 regulates the capacity of dendritic cells to promote NKT-cell-induced liver injury

artículo científico publicado en 2014

Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model

artículo científico publicado en 2010

Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens

artículo científico publicado en 2008

Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients.

artículo científico publicado en 2011

Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis

artículo científico publicado en 2017

Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils ⬇️

artículo científico publicado el 1 de mayo de 1998

Galectin-3 binds lactosaminylated lipooligosaccharides from Neisseria gonorrhoeae and is selectively expressed by mucosal epithelial cells that are infected

artículo científico publicado en 2002

Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice

artículo científico publicado en 2012

Galectin-3 deficiency protects pancreatic islet cells from cytokine-triggered apoptosis in vitro.

artículo científico publicado en 2013

Galectin-3 endocytosis by carbohydrate independent and dependent pathways in different macrophage like cell types

artículo científico publicado en 2012

Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils

artículo científico publicado en 2008

Galectin-3 guides intracellular trafficking of some human serotransferrin glycoforms

artículo científico publicado en 2013

Galectin-3 inhibits Schwann cell proliferation in cultured sciatic nerve

scientific article published on 01 May 2007

Galectin-3 targeted therapy with a small molecule inhibitor activates apoptosis and enhances both chemosensitivity and radiosensitivity in papillary thyroid cancer

artículo científico publicado en 2009

Galectin-3 type-C self-association on neutrophil surfaces; The carbohydrate recognition domain regulates cell function

artículo científico publicado en 2018

Galectin-3, a marker for vacuole lysis by invasive pathogens.

artículo científico publicado en 2009

Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

artículo científico publicado en 2016

Galectin-4 and galectin-6 are two closely related lectins expressed in mouse gastrointestinal tract.

artículo científico publicado en 1998

Galectin-4 in normal tissues and cancer

artículo científico publicado en 2004

Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins.

artículo científico publicado en 2011

Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells

artículo científico publicado en 2008

Galectins structure and function--a synopsis.

artículo científico publicado en 2001

Galectins. Structure and function of a large family of animal lectins

artículo científico publicado en 1994

Gangliotetraosylceramide is a major glycolipid of epithelial cells of mouse small intestine

scientific article published on 01 March 1982

Glycoconjugate Receptors Involved in the Adhesion of Escherichia coli and Streptococcus pneumoniae to Epithelial Cells ⬇️

artículo científico publicado el 1 de marzo de 1984

Glycoconjugate receptors for bacteria attaching to mucosal sites: examples for Escherichia coli and Streptococcus pneumoniae

artículo científico publicado en 1987

Glycolipid receptors for uropathogenic Escherichia coli on human erythrocytes and uroepithelial cells.

artículo científico publicado en 1981

Glycolipids of rat small intestine. Characterization of a novel blood group H-active triglycosylceramide

artículo científico publicado en 1980

Glycoproteomic identification of galectin-3 and -8 ligands in bronchoalveolar lavage of mild asthmatics and healthy subjects

artículo científico publicado en 2012

Glycosphingolipid composition of epithelial cells isolated along the villus axis of small intestine of a single human individual.

artículo científico publicado en 2012

Glycosphingolipid receptors for Pseudomonas aeruginosa

artículo científico publicado en 1990

Glycosphingolipids and the differentiation of intestinal epithelium

artículo científico publicado en 1981

Glycosphingolipids of human urinary tract epithelial cells as possible receptors for adhering Escherichia coli bacteria

artículo científico publicado en 1980

Glycosphingolipids of rat tissues. Different composition of epithelial and nonepithelial cells of small intestine

artículo científico publicado en 1982

Human blood group A-positive and -negative strains of rat. Chemical basis as shown by fucolipids of small intestine

artículo científico publicado en 1980

Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity

artículo científico publicado en 1998

Human trophoblast requires galectin-3 for cell migration and invasion

artículo científico publicado en 2019

Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils

artículo científico publicado en 1999

Identification of an active disaccharide unit of a glycoconjugate receptor for pneumococci attaching to human pharyngeal epithelial cells

artículo científico publicado en 1983

Identification of the sulfated monosaccharides of GlyCAM-1, an endothelial-derived ligand for L-selectin

artículo científico publicado en 1994

Identifying bacterial receptor proteins and quantifying strength of interactions they mediate

artículo científico publicado en 1995

Immunohistochemical Studies on Galectin Expression in Colectomised Patients with Ulcerative Colitis

artículo científico publicado en 2016

In Vivo Veritas: 18F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors

scientific article published on 03 January 2020

Influence of adhesins on the interaction of Escherichia coli with human phagocytes

artículo científico publicado en 1984

Influence of blood group on the availability of receptors for attachment of uropathogenic Escherichia coli

artículo científico publicado en 1986

Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor

artículo científico publicado en 2012

Inhibition of bacterial attachment: examples from the urinary and respiratory tracts

artículo científico

Inhibition of experimental ascending urinary tract infection by an epithelial cell-surface receptor analogue

artículo científico publicado en 1982

Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding

scientific article published on 23 January 2019

Intracellular sorting of galectin-8 based on carbohydrate fine specificity

artículo científico publicado en 2007

Introduction to galectins

artículo científico publicado en 2004

Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors

artículo científico publicado en 2013

Isolation and expression of a gene encoding L-14-II, a new human soluble lactose-binding lectin ⬇️

artículo científico publicado el 25 de mayo de 1992

Isolation and partial characterization of blood group A and H active glycosphingolipids of rat small intestine

scientific article published on 01 January 1982

L-29, a soluble lactose-binding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I.

artículo científico publicado en 1993

L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity

artículo científico publicado en 1993

Ligand binding and complex formation of galectin-3 is modulated by pH variations

artículo científico publicado en 2014

Ligand induced galectin-3 protein self-association

artículo científico publicado en 2012

Lipopolysaccharide-induced gelatinase granule mobilization primes neutrophils for activation by galectin-3 and formylmethionyl-Leu-Phe

artículo científico publicado en 2001

Low micromolar inhibitors of galectin-3 based on 3'-derivatization of N-acetyllactosamine

artículo científico publicado en 2002

Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans

artículo científico publicado en 2016

Macrophage inflammatory protein-2 is required for neutrophil passage across the epithelial barrier of the infected urinary tract

scientific article published on 01 March 1999

Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.

artículo científico publicado en 2015

Molecular characterization of alpha-lactalbumin folding variants that induce apoptosis in tumor cells

artículo científico publicado en 1999

Molecular mechanisms of adhesion of Streptococcus pneumoniae to human oropharyngeal epithelial cells.

artículo científico publicado en 1983

Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-π, and Halogen Bond Interactions.

artículo científico publicado en 2017

Monovalent interactions of galectin-1

artículo científico publicado en 2010

Multimeric lactoside "click clusters" as tools to investigate the effect of linker length in specific interactions with peanut lectin, galectin-1, and -3.

artículo científico publicado en 2010

Multiple soluble beta-galactoside-binding lectins from human lung

scientific article published on 01 May 1987

Multiple soluble vertebrate galactoside-binding lectins

artículo científico publicado en 1988

Mutational tuning of galectin-3 specificity and biological function

artículo científico publicado en 2010

Newcastle disease virus neuraminidase primes neutrophils for stimulation by galectin-3 and formyl-Met-Leu-Phe

artículo científico publicado en 2004

Non-antibiotic prevention of urinary tract infection

artículo científico publicado en 1985

Non-antibiotic prevention of urinary tract infection

artículo científico publicado en 1984

Non-antibody-containing fractions of breast milk inhibit epithelial attachment of Streptococcus pneumoniae and Haemophilus influenzae

scientific article published on 01 March 1985

Novel polyfucosylated N-linked glycopeptides with blood group A, H, X, and Y determinants from human small intestinal epithelial cells

artículo científico publicado en 1989

P blood group and proneness to urinary tract infection in Japanese children

artículo científico publicado en 1989

P1 blood group and urinary tract infection

artículo científico publicado en 1981

Palmitoyl carnitine, a lysophospholipase-transacylase inhibitor, prevents Candida adherence in vitro

artículo científico publicado en 1997

Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3.

artículo científico publicado en 2016

Phylogenetic analysis of the vertebrate galectin family

artículo científico publicado en 2004

Possible interaction between animal lectins and bacterial carbohydrates.

artículo científico publicado en 1994

Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase

artículo científico publicado en 1993

Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3

artículo científico publicado en 2010

Protein identification by in-gel digestion, high-performance liquid chromatography, and mass spectrometry: peptide analysis by complementary ionization techniques.

artículo científico publicado en 2001

Protein subtype-targeting through ligand epimerization: talose-selectivity of galectin-4 and galectin-8.

artículo científico publicado en 2008

Recent progress in the understanding of the role of bacterial adhesion in the pathogenesis of urinary tract infection

artículo científico publicado en 1982

Receptor analogues and anti-pili antibodies as inhibitors of bacterial attachment in vivo and in vitro

artículo científico publicado en 1983

Receptor-specific agglutination tests for detection of bacteria that bind globoseries glycolipids

artículo científico publicado en 1987

Regulation of alternative macrophage activation by galectin-3.

artículo científico publicado en 2008

Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3

artículo científico publicado en 2012

Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340.

artículo científico publicado en 2000

Sd(a)-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon

artículo científico publicado en 2001

Selected ion monitoring of glycospingolipid mixtures. Identification of several blood group type glycolipids in the small intestine of an individual rabbit

scientific article published on 01 June 1979

Separate oligosaccharide determinants mediate interactions of the low-molecular-weight salivary mucin with neutrophils and bacteria

artículo científico publicado en 1999

Separation and Characterization of Hematosides with Different Sialic Acids and Ceramides from Rat Small Intestine. Different Composition of Epithelial Cells versus Non-Epithelial Tissue and of Duodenum versus Jejunum-Ileum1 ⬇️

artículo científico publicado el 1 de octubre de 1981

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes

scientific journal article

Sequence and specificity of a soluble lactose-binding lectin from Xenopus laevis skin.

artículo científico publicado en 1992

Sequence, structure, and chromosomal mapping of the mouse Lgals6 gene, encoding galectin-6.

artículo científico publicado en 1998

Sequencing of large oligosaccharides by direct inlet mass spectrometry. Application to cell surface glycolipids

Sequencing of oligosaccharides by mass spectrometry applied on a 12-sugar glycolipid

scientific article published on 01 February 1981

Soluble lactose-binding lectin from rat intestine with two different carbohydrate-binding domains in the same peptide chain

artículo científico publicado en 1993

Soluble lactose-binding lectins from chicken and rat.

artículo científico publicado en 1987

Soluble lactose-binding vertebrate lectins: a growing family

artículo científico publicado en 1989

Specific adherence of Candida tropicalis to lysophospholipids

artículo científico publicado en 1994

Specific pattern of glycosphingolipids enriched in a mucosa scraping of human small intestine

artículo científico publicado en 1979

Specificity of binding of a strain of uropathogenic Escherichia coli to Gal alpha 1----4Gal-containing glycosphingolipids

artículo científico publicado en 1985

Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides

artículo científico publicado en 1986

Spindle pole cohesion requires glycosylation-mediated localization of NuMA.

artículo científico publicado en 2017

Stereo- and regioselective hydroboration of 1-exo-methylene pyranoses: discovery of aryltriazolylmethyl C-galactopyranosides as selective galectin-1 inhibitors.

artículo científico publicado en 2019

Strategies for studying bacterial adhesion in vivo.

artículo científico publicado en 1995

Strikingly different localization of galectin-3 and galectin-4 in human colon adenocarcinoma T84 cells. Galectin-4 is localized at sites of cell adhesion

artículo científico publicado en 1997

Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction

artículo científico publicado en 2005

Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3'-sulfo-lactose, and 2'-fucosyllactose

artículo científico

Structural characterization of glycolipids of rat small intestine having one to eight hexoses in a linear sequence

artículo científico publicado en 1982

Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens

artículo científico publicado en 2015

Structure and Energetics of Ligand-Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions

artículo científico publicado en 2019

Structure and bacterial receptor activity of a human salivary proline-rich glycoprotein

artículo científico publicado en 1991

Structure determination of blood group type glycolipids of cat small intestine by mass fragmentography

scientific article published on 01 May 1978

Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectin

artículo científico

Structures of blood group glycosphingolipids of human small intestine. A relation between the expression of fucolipids of epithelial cells and the ABO, Le and Se phenotype of the donor

scientific article published on 01 May 1987

Studies of arginine-arene interactions through synthesis and evaluation of a series of galectin-binding aromatic lactose esters

artículo científico

Studies on differentiating epithelial cells of rat small intestine. Alterations in the lipophilic part of glycosphingolipids during cell migration from crypt villus tip

artículo científico publicado en 1982

Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects

scientific article published on 01 January 2019

Sulfated lewis X determinants as a major structural motif in glycans from LS174T-HM7 human colon carcinoma mucin.

artículo científico publicado en 1997

Superantigen- and TLR-dependent activation of tonsillar B cells after receptor-mediated endocytosis

artículo científico publicado en 2009

Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists

artículo científico publicado en 2014

Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3.

artículo científico publicado en 2009

Synthesis of O-galactosyl aldoximes as potent LacNAc-mimetic galectin-3 inhibitors

artículo científico publicado en 2005

Synthesis of a 3'-naphthamido-LacNAc fluorescein conjugate with high selectivity and affinity for galectin-3

scientific article published on 15 May 2006

Synthesis of a phenyl thio-beta-D-galactopyranoside library from 1,5-difluoro-2,4-dinitrobenzene: discovery of efficient and selective monosaccharide inhibitors of galectin-7.

artículo científico publicado en 2005

Synthesis of galactose-mimicking 1H-(1,2,3-triazol-1-yl)-mannosides as selective galectin-3 and 9N inhibitors

scientific article published on 14 March 2007

Synthesis of multivalent lactose derivatives by 1,3-dipolar cycloadditions: selective galectin-1 inhibition

scientific article published on 15 May 2006

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

artículo científico publicado en 2017

Taloside inhibitors of galectin-1 and galectin-3

artículo científico publicado en 2012

Target cell specificity of wild-type E. coli and mutants and clones with genetically defined adhesins

artículo científico publicado el 1 de enero de 1983

The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics

artículo científico publicado en 2012

The High-Molecular-Weight Human Mucin Is the Primary Salivary Carrier of ABH, Lea, and Leb Blood Group Antigens ⬇️

artículo científico publicado el 1 de enero de 1993

The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin.

artículo científico publicado en 2018

The animal lectin galectin-3 interacts with bacterial lipopolysaccharides via two independent sites

artículo científico publicado en 1996

The anti-angiogenic peptide anginex greatly enhances galectin-1 binding affinity for glycoproteins

artículo científico publicado en 2011

The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the a

artículo científico publicado en 2008

The preparative separation of sialic acid-containing lipids from sulphate group-containing glycolipids from small intestine of different animals. Analysis by thin-layer chromatography and detection of novel species

artículo científico publicado en 1983

The receptor repertoire defines the host range for attaching Escherichia coli strains that recognize globo-A.

artículo científico publicado en 1991

The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading

scientific article published on 11 October 2008

The salivary mucin MG1 (MUC5B) carries a repertoire of unique oligosaccharides that is large and diverse

artículo científico publicado en 2002

The specific glycosphingolipid composition of human ureteral epithelial cells

artículo científico publicado en 1985

The structure of sphingomyelin of the honey bee (Apis mellifera).

artículo científico publicado en 1972

Thioureido N-acetyllactosamine derivatives as potent galectin-7 and 9N inhibitors

artículo científico publicado en 2005

Truncated galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer

artículo científico publicado en 2003

Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1

scientific article published on 23 January 2013

Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13.

artículo científico publicado en 1993

Variant size- and glycoforms of the scavenger receptor cysteine-rich protein gp-340 with differential bacterial aggregation

artículo científico publicado en 2007

Virulence-associated traits in Escherichia coli causing first and recurrent episodes of urinary tract infection in children with or without vesicoureteral reflux

artículo científico publicado en 1984

X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution

artículo científico publicado en 1993

X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution

artículo científico publicado en 1998

[Bacterial binding and urinary tract infections]

artículo científico publicado en 1982

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

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