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Lista de obras de Ana M. Sebastião

A1 and A2A receptor activation by endogenous adenosine is required for VIP enhancement of K+ -evoked [3H]-GABA release from rat hippocampal nerve terminals.

artículo científico publicado en 2007

A1R-A2AR heteromers coupled to Gs and G i/0 proteins modulate GABA transport into astrocytes.

artículo científico publicado en 2013

Activation of adenosine A2A receptor facilitates brain-derived neurotrophic factor modulation of synaptic transmission in hippocampal slices.

artículo científico publicado en 2004

Activation of adenosine A2A receptors induces TrkB translocation and increases BDNF-mediated phospho-TrkB localization in lipid rafts: implications for neuromodulation

artículo científico publicado en 2010

Activation of type 1 cannabinoid receptor (CB1R) promotes neurogenesis in murine subventricular zone cell cultures

artículo científico publicado en 2013

Adenine nucleotide analogues, including gamma-phosphate-substituted analogues, are metabolised extracellularly in innervated frog sartorius muscle

artículo científico publicado el 3 de noviembre de 1992

Adenosine A(2A) Receptors as novel upstream regulators of BDNF-mediated attenuation of hippocampal Long-Term Depression (LTD).

artículo científico publicado en 2013

Adenosine A(2A) receptor blockade reverts hippocampal stress-induced deficits and restores corticosterone circadian oscillation.

artículo científico publicado en 2012

Adenosine A(2A) receptor modulation of hippocampal CA3-CA1 synapse plasticity during associative learning in behaving mice

artículo científico publicado en 2009

Adenosine A1 Receptor Suppresses Tonic GABAA Receptor Currents in Hippocampal Pyramidal Cells and in a Defined Subpopulation of Interneurons

artículo científico publicado en 2014

Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes.

artículo científico publicado en 2015

Adenosine A2A receptors activation facilitates neuromuscular transmission in the pre-symptomatic phase of the SOD1(G93A) ALS mice, but not in the symptomatic phase.

artículo científico publicado en 2014

Adenosine A2A receptors control the extracellular levels of adenosine through modulation of nucleoside transporters activity in the rat hippocampus.

artículo científico publicado en 2005

Adenosine A2A receptors enhance GABA transport into nerve terminals by restraining PKC inhibition of GAT-1.

artículo científico publicado en 2009

Adenosine A2A receptors facilitate synaptic NMDA currents in CA1 pyramidal neurons.

artículo científico publicado en 2018

Adenosine A2A receptors in neuronal outgrowth: a target for nerve regeneration?

artículo científico publicado en 2016

Adenosine A2A receptors stimulate acetylcholine release from nerve terminals of the rat hippocampus

scientific article published on 01 August 1995

Adenosine Kinase Deficiency in the Brain Results in Maladaptive Synaptic Plasticity.

artículo científico publicado en 2016

Adenosine and Related Drugs in Brain Diseases: Present and Future in Clinical Trials

artículo científico publicado el 1 de enero de 2011

Adenosine and adenine nucleotides are independently released from both the nerve terminals and the muscle fibres upon electrical stimulation of the innervated skeletal muscle of the frog

scientific article published on 01 September 1993

Adenosine and epilepsy-thinking beyond A(1) receptors.

artículo científico publicado en 2010

Adenosine by activating A1 receptors prevents GABAA-mediated actions during hypoxia in the rat hippocampus

artículo científico publicado en 1996

Adenosine inhibits human astrocyte proliferation independently of adenosine receptor activation

scientific article published on 07 December 2019

Adenosine receptor interactions in the hippocampus

Adenosine receptors and the central nervous system.

scientific article published on January 2009

Adenosine receptors in the nervous system: pathophysiological implications.

artículo científico publicado en 2002

Adenosine: does it have a neuroprotective role after all?

artículo científico publicado en 2000

Adenosine: setting the stage for plasticity

artículo científico publicado el 15 de enero de 2013

Age-related changes of glycine receptor at the rat hippocampus: from the embryo to the adult.

artículo científico publicado en 2011

Amyotrophic Lateral Sclerosis (ALS) and Adenosine Receptors.

artículo científico publicado en 2018

An adenosine analogue inhibits NMDA receptor-mediated responses in bipolar cells of the rat retina

artículo científico publicado en 1999

Anxiety Assessment in Pre-clinical Tests and in Clinical Trials: A Critical Review

artículo científico publicado en 2018

Ascorbate/Fe(3+)-induced peroxidation and inhibition of the binding of A1 adenosine receptor ligands in rat brain membranes

scientific article published on 01 March 1995

Axonal elongation and dendritic branching is enhanced by adenosine A2A receptors activation in cerebral cortical neurons

artículo científico publicado en 2015

BDNF modulates glycine uptake in hippocampal synaptosomes by decreasing membrane insertion of glycine transporter 2.

artículo científico publicado en 2016

BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes.

artículo científico publicado en 2015

BDNF-induced presynaptic facilitation of GABAergic transmission in the hippocampus of young adults is dependent of TrkB and adenosine A2A receptors.

artículo científico publicado en 2016

Biological activities of N6,C8-disubstituted adenosine derivatives as partial agonists at rat brain adenosine A1 receptors

artículo científico publicado en 1997

Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis

artículo científico publicado en 2018

Brain-derived neurotrophic factor (BDNF) enhances GABA transport by modulating the trafficking of GABA transporter-1 (GAT-1) from the plasma membrane of rat cortical astrocytes

artículo científico publicado en 2011

Brain-derived neurotrophic factor facilitates glutamate and inhibits GABA release from hippocampal synaptosomes through different mechanisms

artículo científico publicado en 2004

Brain-derived neurotrophic factor inhibits GABA uptake by the rat hippocampal nerve terminals

artículo científico publicado en 2008

Brain-derived neurotrophic factor mediates neuroprotection against Aβ-induced toxicity through a mechanism independent on adenosine 2A receptor activation

artículo científico publicado en 2015

Caffeine and adenosine.

artículo científico publicado en 2010

Caffeine has a dual influence on NMDA receptor-mediated glutamatergic transmission at the hippocampus

artículo científico publicado en 2020

Calcitonin gene-related peptide in the hamster seminal vesicle and coagulating gland: an immunohistochemical, autoradiographical, and pharmacological study

artículo científico publicado en 1996

Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology

scientific article published on 05 April 2019

Cannabinoid CB(1) and adenosine A(1) receptors independently inhibit hippocampal synaptic transmission

artículo científico publicado en 2009

Challenges and promises in the development of neurotrophic factor-based therapies for Parkinson's disease.

artículo científico

Chronic and acute adenosine A2A receptor blockade prevents long-term episodic memory disruption caused by acute cannabinoid CB1 receptor activation

artículo científico publicado en 2017

Chronic, intermittent treatment with a cannabinoid receptor agonist impairs recognition memory and brain network functional connectivity

scientific article published on 27 September 2018

Control of glutamate release by complexes of adenosine and cannabinoid receptors

scientific article published on 23 January 2020

Depression Assessment in Clinical Trials and Pre-clinical Tests: A Critical Review

artículo científico publicado en 2018

Differential role of the proteasome in the early and late phases of BDNF-induced facilitation of LTP.

artículo científico publicado en 2015

Dissecting neurovascular coupling mechanisms: a role for adenosine A2A receptor: An Editorial highlight for 'Correlation of transient adenosine release and oxygen changes in the caudate-putamen'.

artículo científico publicado en 2016

Dissecting striatal adenosine-cannabinoid receptor interactions. New clues from rats over-expressing adenosine A2A receptors.

artículo científico publicado en 2016

Dopamine-galanin receptor heteromers modulate cholinergic neurotransmission in the rat ventral hippocampus.

artículo científico publicado en 2011

Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an Early Stage

artículo científico publicado en 2017

Dual Influence of Endocannabinoids on Long-Term Potentiation of Synaptic Transmission.

artículo científico publicado en 2017

Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain

artículo científico publicado en 2014

Early changes of neuromuscular transmission in the SOD1(G93A) mice model of ALS start long before motor symptoms onset

artículo científico publicado en 2013

Ecto-5'-nucleotidase is associated with cholinergic nerve terminals in the hippocampus but not in the cerebral cortex of the rat.

artículo científico publicado en 1992

Effect of 5'-(N-ethylcarboxamido)adenosine on adenosine transport in cultured chromaffin cells

artículo científico publicado en 1990

Effects of carbamazepine and novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives on synaptic transmission in rat hippocampal slices

artículo científico publicado en 2002

Endogenous adenosine modulation of 22Na uptake by rat brain synaptosomes

artículo científico publicado en 2003

Enhanced LTP in aged rats: Detrimental or compensatory?

artículo científico publicado en 2016

Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats

artículo científico publicado en 2003

Enhancement of AMPA currents and GluR1 membrane expression through PKA‐coupled adenosine A2A receptors

artículo científico publicado el 15 de noviembre de 2010

Enhancement of LTP in aged rats is dependent on endogenous BDNF.

artículo científico publicado en 2011

Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine

artículo científico publicado en 2008

Enhancement of transmission at the frog neuromuscular junction by adenosine deaminase: evidence for an inhibitory role of endogenous adenosine on neuromuscular transmission

scientific article published on 01 December 1985

Evidence for functionally important adenosine A2a receptors in the rat hippocampus.

artículo científico publicado en 1994

Evidence for the presence of excitatory A2 adenosine receptors in the rat hippocampus

artículo científico publicado en 1992

Ex vivo model of epilepsy in organotypic slices-a new tool for drug screening

scientific article published on 11 July 2018

Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.

artículo científico publicado en 2012

Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog

artículo científico publicado en 1991

From A1 to A3 en passant Through A2A Receptors in the Hippocampus: Pharmacological Implications

artículo científico publicado el 1 de septiembre de 2012

Further evidence for adenosine A3 receptors.

artículo científico publicado en 1994

GAT-3 Dysfunction Generates Tonic Inhibition in External Globus Pallidus Neurons in Parkinsonian Rodents

artículo científico publicado en 2018

Glial cell line-derived neurotrophic factor (GDNF) enhances dopamine release from striatal nerve endings in an adenosine A2A receptor-dependent manner.

artículo científico publicado en 2006

Glutamate Transporters in Hippocampal LTD/LTP: Not Just Prevention of Excitotoxicity

scientific article published on 06 August 2019

GlyT1 and GlyT2 in brain astrocytes: expression, distribution and function

artículo científico publicado en 2013

Glycine Receptor Activation Impairs ATP-Induced Calcium Transients in Cultured Cortical Astrocytes.

artículo científico publicado en 2017

Hippocampal GABAergic transmission: a new target for adenosine control of excitability

artículo científico publicado en 2016

Hippocampal synaptic dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis: Reversal by adenosine A2AR blockade

scientific article published on 17 April 2020

Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase.

artículo científico publicado en 2012

Homeostatic plasticity induced by brief activity deprivation enhances long-term potentiation in the mature rat hippocampus

artículo científico publicado en 2014

Hypoxia-ischemia alters nucleotide and nucleoside catabolism and Na+,K+-ATPase activity in the cerebral cortex of newborn rats.

artículo científico publicado en 2013

Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP.

artículo científico publicado en 2014

Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice.

artículo científico publicado en 2011

In vivo Bio-Distribution and Toxicity Evaluation of Polymeric and Lipid-Based Nanoparticles: A Potential Approach for Chronic Diseases Treatment

artículo científico publicado en 2020

Influence of age on BDNF modulation of hippocampal synaptic transmission: interplay with adenosine A2A receptors.

artículo científico publicado en 2007

Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β.

artículo científico publicado en 2018

Inhibitory and excitatory effects of adenosine receptor agonists on evoked transmitter release from phrenic nerve endings of the rat

artículo científico publicado el 1 de junio de 1991

Interaction between Cannabinoid Type 1 and Type 2 Receptors in the Modulation of Subventricular Zone and Dentate Gyrus Neurogenesis

artículo científico

Interactions between adenosine and phorbol esters or lithium at the frog neuromuscular junction

artículo científico publicado en 1990

Interleukin-6 upregulates neuronal adenosine A1 receptors: implications for neuromodulation and neuroprotection.

artículo científico publicado en 2007

Ischemia-induced synaptic plasticity drives sustained expression of calcium-permeable AMPA receptors in the hippocampus

artículo científico publicado en 2012

Lipid rafts, synaptic transmission and plasticity: Impact in age-related neurodegenerative diseases

artículo científico publicado el 20 de julio de 2012

Maternal separation impairs long term-potentiation in CA1-CA3 synapses and hippocampal-dependent memory in old rats

artículo científico publicado en 2014

Mechanisms of regulation of olfactory transduction and adaptation in the olfactory cilium.

artículo científico publicado en 2014

Memory deficits induced by chronic cannabinoid exposure are prevented by adenosine A2AR receptor antagonism

artículo científico publicado en 2019

MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins.

artículo científico publicado en 2014

Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

artículo científico publicado en 2020

Modeling the functional network of primary intercellular Ca2+ wave propagation in astrocytes and its application to study drug effects.

artículo científico publicado en 2014

Modulation of GABA transport by adenosine A1R-A2AR heteromers, which are coupled to both Gs- and G(i/o)-proteins

scientific article published on 01 November 2011

Modulation of cGMP accumulation by adenosine A1 receptors at the hippocampus: influence of cGMP levels and gender

artículo científico publicado en 2014

Modulation of subventricular zone oligodendrogenesis: a role for hemopressin?

artículo científico publicado en 2014

Multicompartment Microreactors Prevent Excitotoxic Dysfunctions In Rat Primary Cortical Neurons

scientific article published on 31 August 2020

N6-cyclohexyladenosine inhibits veratridine-stimulated 22Na uptake by rat brain synaptosomes

artículo científico publicado en 1988

Neural Stem Cells and Cannabinoids in the Spotlight as Potential Therapy for Epilepsy

artículo científico publicado en 2020

Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells.

artículo científico publicado en 2015

Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10.

artículo científico publicado en 2012

Neuroinflammation after neonatal hypoxia-ischemia is associated with alterations in the purinergic system: adenosine deaminase 1 isoenzyme is the most predominant after insult

artículo científico publicado en 2015

Neuromodulation and metamodulation by adenosine: Impact and subtleties upon synaptic plasticity regulation.

artículo científico publicado en 2014

Neuromuscular transmission modulation by adenosine upon aging.

artículo científico publicado en 2012

Neuronal ENT1 takes up synaptic adenosine even under hypoxia/ischemia

artículo científico publicado el 19 de mayo de 2011

Neuroprotection afforded by adenosine A2A receptor blockade is modulated by corticotrophin-releasing factor (CRF) in glutamate injured cortical neurons

artículo científico publicado en 2012

Nitric oxide mediates interactions between GABAA receptors and adenosine A1 receptors in the rat hippocampus

artículo científico publicado en 2006

On the high affinity of 8-cyclohexylcaffeine for the presynaptic inhibitory adenosine receptor present in rat motor nerve terminals

artículo científico publicado en 1997

On the type of receptor involved in the inhibitory action of adenosine at the neuromuscular junction

artículo científico publicado en 1985

P2Y1 receptor inhibits GABA transport through a calcium signalling-dependent mechanism in rat cortical astrocytes.

artículo científico publicado en 2014

Pertussis toxin-sensitive G proteins mediate the inhibition of basal phosphoinositide metabolism caused by adenosine A1 receptors in rat hippocampal slices.

artículo científico publicado en 2002

Platinum Nanoparticle-Based Microreactors as Support for Neuroblastoma Cells

artículo científico publicado en 2017

Postsynaptic action of brain-derived neurotrophic factor attenuates alpha7 nicotinic acetylcholine receptor-mediated responses in hippocampal interneurons.

artículo científico publicado en 2008

Predominance of adenosine excitatory over inhibitory effects on transmission at the neuromuscular junction of infant rats

artículo científico publicado en 2009

Presymptomatic and symptomatic ALS SOD1(G93A) mice differ in adenosine A1 and A2A receptor-mediated tonic modulation of neuromuscular transmission

artículo científico publicado en 2015

Purine nucleosides in neuroregeneration and neuroprotection.

artículo científico publicado en 2015

Purinergic modulation of the evoked release of [3H]acetylcholine from the hippocampus and cerebral cortex of the rat: role of the ectonucleotidases

artículo científico publicado en 1994

Rare Diseases of Neurodevelopment: Maintain the Mystery or Use a Dazzling Tool for Investigation? The Case of Rett Syndrome

scientific article published on 21 June 2019

Regulation of TrkB receptor translocation to lipid rafts by adenosine A(2A) receptors and its functional implications for BDNF-induced regulation of synaptic plasticity

artículo científico publicado en 2013

Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9-tetrahydrocannabinol on spatial memory

artículo científico publicado en 2011

Solubilized rat brain adenosine receptors have two high-affinity binding sites for 1,3-dipropyl-8-cyclopentylxanthine

artículo científico publicado en 1991

Spintronic platforms for biomedical applications.

artículo científico publicado en 2011

Subtypes of adenosine receptors

artículo científico publicado en 1988

Synaptic mechanisms of adenosine A2A receptor-mediated hyperexcitability in the hippocampus

artículo científico publicado en 2014

Tauroursodeoxycholic Acid Enhances Mitochondrial Biogenesis, Neural Stem Cell Pool, and Early Neurogenesis in Adult Rats

artículo científico publicado en 2017

Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice.

artículo científico publicado en 2012

The Role of cGMP on Adenosine A 1 Receptor-mediated Inhibition of Synaptic Transmission at the Hippocampus.

artículo científico publicado en 2016

The combined inhibitory effect of the adenosine A1 and cannabinoid CB1 receptors on cAMP accumulation in the hippocampus is additive and independent of A1 receptor desensitization

artículo científico publicado en 2015

The giant miniature endplate potentials frequency is increased in aged rats

artículo científico publicado en 2014

The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines.

artículo científico publicado en 1990

Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus

artículo científico publicado en 2006

Triggering of BDNF facilitatory action on neuromuscular transmission by adenosine A2A receptors.

artículo científico publicado en 2006

TrkB-ICD Fragment, Originating From BDNF Receptor Cleavage, Is Translocated to Cell Nucleus and Phosphorylates Nuclear and Axonal Proteins

artículo científico publicado en 2019

Tuning and fine-tuning of synapses with adenosine.

artículo científico publicado en 2009

VIP enhances both pre- and postsynaptic GABAergic transmission to hippocampal interneurones leading to increased excitatory synaptic transmission to CA1 pyramidal cells.

artículo científico publicado en 2004

VIP enhances synaptic transmission to hippocampal CA1 pyramidal cells through activation of both VPAC1 and VPAC2 receptors.

artículo científico publicado en 2005

VPAC1 and VPAC2 receptor activation on GABA release from hippocampal nerve terminals involve several different signalling pathways.

artículo científico publicado en 2017

VPAC2 receptor activation mediates VIP enhancement of population spikes in the CA1 area of the hippocampus

artículo científico publicado en 2006