Lista de obras - Roland Houben - Dominio Público Uruguay

Activation of the MAP kinase pathway induces apoptosis in the Merkel cell carcinoma cell line UISO.

artículo científico publicado en 2007

Activation of the PI3K/AKT pathway in Merkel cell carcinoma

artículo científico publicado en 2012

An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells

artículo científico publicado en 2011

Artesunate Affects T Antigen Expression and Survival of Virus-Positive Merkel Cell Carcinoma

artículo científico publicado en 2020

BIK is involved in BRAF/MEK inhibitor induced apoptosis in melanoma cell lines.

artículo científico publicado en 2017

BRAF inhibition causes resilience of melanoma cell lines by inducing the secretion of FGF1

artículo científico publicado en 2018

CD147 impacts angiogenesis and metastasis formation.

artículo científico publicado en 2009

Characterization of functional domains in the Merkel cell polyoma virus Large T antigen

artículo científico publicado en 2014

Characterization of six Merkel cell polyomavirus-positive Merkel cell carcinoma cell lines: Integration pattern suggest that large T antigen truncating events occur before or during integration

scientific article published on 04 April 2019

Coincident Metastatic Melanoma and Merkel Cell Carcinoma with Complete Remission on Treatment with Pembrolizumab

artículo científico publicado en 2017

Combination with γ-secretase inhibitor prolongs treatment efficacy of BRAF inhibitor in BRAF-mutated melanoma cells.

artículo científico publicado en 2016

Comparable expression and phosphorylation of the retinoblastoma protein in Merkel cell polyoma virus-positive and negative Merkel cell carcinoma

artículo científico publicado en 2010

Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis

artículo científico publicado en 2004

Dendritic cell based antitumor vaccination: impact of functional indoleamine 2,3-dioxygenase expression.

artículo científico publicado en 2006

Detection of the Merkel cell polyomavirus in the neuroendocrine component of combined Merkel cell carcinoma.

artículo científico publicado en 2018

Diagnostic accuracy of a panel of immunohistochemical and molecular markers to distinguish Merkel cell carcinoma from other neuroendocrine carcinomas

artículo científico publicado en 2018

Differential gene expression in apoptotic 32Dcl3 cells: induction of metallothionein.

artículo científico publicado en 1997

Distinction of 2 different primary Merkel cell carcinomas in 1 patient by Merkel cell polyomavirus genome analysis.

artículo científico publicado en 2010

Elucidating the mechanism of action of domatinostat (4SC-202) in cutaneous T cell lymphoma cells

artículo científico publicado en 2019

Expression of Merkelcell polyomavirus (MCPyV) large T-antigen in Merkel cell carcinoma lymph node metastases predicts poor outcome.

artículo científico publicado en 2017

Expression of the tetraspanins CD9, CD37, CD63, and CD151 in Merkel cell carcinoma: strong evidence for a posttranscriptional fine-tuning of CD9 gene expression

artículo científico publicado en 2010

Immunogenicity of constitutively active V599EBRaf

artículo científico publicado en 2004

Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy

artículo científico publicado en 2007

LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression

artículo científico publicado en 2015

Lack of Wnt5A expression in Merkel cell carcinoma.

scientific article published on January 2010

Lack of correlation between IGFBP7 expression and BRAF mutational status in melanoma

artículo científico publicado en 2009

MAPK-independent impairment of T-cell responses by the multikinase inhibitor sorafenib

artículo científico publicado en 2009

MC polyomavirus is frequently present in Merkel cell carcinoma of European patients.

artículo científico publicado en 2008

Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.

artículo científico publicado en 2007

Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens.

artículo científico publicado en 2013

Melanoma stem cells: targets for successful therapy?

artículo científico publicado en 2008

Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression.

artículo científico publicado en 2017

Merkel Cell Polyomavirus Large T Antigen is Dispensable in G2 and M-Phase to Promote Proliferation of Merkel Cell Carcinoma Cells

artículo científico publicado en 2020

Merkel Cell Polyomavirus T Antigens Induce Merkel Cell-Like Differentiation in GLI1-Expressing Epithelial Cells

artículo científico publicado en 2020

Merkel cell carcinoma and Merkel cell polyomavirus: evidence for hit-and-run oncogenesis

artículo científico publicado en 2011

Merkel cell carcinomas infiltrated with CD33+ myeloid cells and CD8+ T cells are associated with improved outcome

artículo científico publicado en 2017

Merkel cell polyomavirus status is not associated with clinical course of Merkel cell carcinoma.

artículo científico publicado en 2011

Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens

artículo científico publicado en 2010

Merkel cell polyomavirus-positive Merkel cell carcinoma cells do not require expression of the viral small T antigen.

artículo científico publicado en 2013

Microencapsulated transplantation of allogeneic islets into specifically presensitized recipients

artículo científico publicado en 1994

Microphthalmia-associated transcription factor gene amplification in metastatic melanoma is a prognostic marker for patient survival, but not a predictive marker for chemosensitivity and chemotherapy response

artículo científico publicado en 2007

Microvessel density and expression of vascular endothelial growth factor and its receptors in different subtypes of primary cutaneous B-cell lymphoma

artículo científico publicado en 2013

Morphologic and immunophenotypical features distinguishing Merkel cell polyomavirus-positive and negative Merkel cell carcinoma

scientific article published on 14 June 2019

No evidence for association of HPyV6 or HPyV7 with different skin cancers

artículo científico publicado en 2011

Overexpression of the KIT/SCF in uveal melanoma does not translate into clinical efficacy of imatinib mesylate.

artículo científico publicado en 2009

Phospho-ERK staining is a poor indicator of the mutational status of BRAF and NRAS in human melanoma.

artículo científico publicado en 2008

Pigmentation, Melanocyte Colonization, and p53 Status in Basal Cell Carcinoma ⬇️

artículo científico publicado el 29 de septiembre de 2010

Production of purified alginates suitable for use in immunoisolated transplantation

artículo científico publicado en 1994

RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells.

artículo científico publicado en 2016

RKIP does not contribute to MAP kinase pathway silencing in the Merkel Cell Carcinoma cell line UISO.

artículo científico publicado en 2007

Regulation of glycolysis by Raf protein serine/threonine kinases

artículo científico publicado en 2002

Response to Shuda et al.

artículo científico publicado en 2013

Response to imatinib mesylate depends on the presence of the V559A-mutated KIT oncogene

artículo científico publicado en 2010

Role of matrix metalloproteinases in melanoma cell invasion

artículo científico publicado en 2005

Serine 220 phosphorylation of the Merkel cell polyomavirus large T antigen crucially supports growth of Merkel cell carcinoma cells.

artículo científico publicado en 2015

Significant correlation of peptidyl-prolyl isomerase overexpression in Merkel cell carcinoma with overall survival of patients

scientific article published on 29 November 2010

Survivin downregulation is not required for T antigen knockdown mediated cell growth inhibition in MCV infected merkel cell carcinoma cells

artículo científico publicado en 2012

The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.

artículo científico publicado en 2014

The TGF-β-inducible miR-23a cluster attenuates IFN-γ levels and antigen-specific cytotoxicity in human CD8⁺ T cells

artículo científico publicado en 2014

The carcinogenic potential of tacrolimus ointment beyond immune suppression: a hypothesis creating case report.

artículo científico publicado en 2006

The effect of resveratrol in combination with irradiation and chemotherapy: study using Merkel cell carcinoma cell lines

artículo científico publicado en 2013

The identification of patient-specific mutations reveals dual pathway activation in most patients with melanoma and activated receptor tyrosine kinases in BRAF/NRAS wild-type melanomas

scientific article published on 18 December 2018

Transplantation of microencapsulated islets in rats: evidence for induction of fibrotic overgrowth by islet alloantigens released from microcapsules

artículo científico publicado en 1994

Type I and II IFNs inhibit Merkel cell carcinoma via modulation of the Merkel cell polyomavirus T antigens.

artículo científico publicado en 2012

Unique Role of Histone Methyltransferase PRDM8 in the Tumorigenesis of Virus-Negative Merkel Cell Carcinoma

scientific article published on 24 April 2020

VEGF-A inhibition as a potential therapeutic approach in Merkel cell carcinoma

article

[Immunologic isolation of transplanted islets of Langerhans: microcapsules with defined molecular limits]

artículo científico publicado en 1993

[Kinase inhibitors for the therapy of malignant melanoma].

artículo científico publicado en 2005

[New therapeutic approaches for solid tumors: histone deacetylase, methyltransferase and proteasome inhibitors].

artículo científico publicado en 2006

p53 regulation by TRP2 is not pervasive in melanoma

artículo científico publicado en 2014

Lista de obras de Roland Houben

Activation of the MAP kinase pathway induces apoptosis in the Merkel cell carcinoma cell line UISO.

Activation of the PI3K/AKT pathway in Merkel cell carcinoma

An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells

Artesunate Affects T Antigen Expression and Survival of Virus-Positive Merkel Cell Carcinoma

BIK is involved in BRAF/MEK inhibitor induced apoptosis in melanoma cell lines.

BRAF inhibition causes resilience of melanoma cell lines by inducing the secretion of FGF1

CD147 impacts angiogenesis and metastasis formation.

Characterization of functional domains in the Merkel cell polyoma virus Large T antigen

Characterization of six Merkel cell polyomavirus-positive Merkel cell carcinoma cell lines: Integration pattern suggest that large T antigen truncating events occur before or during integration

Coincident Metastatic Melanoma and Merkel Cell Carcinoma with Complete Remission on Treatment with Pembrolizumab

Combination with γ-secretase inhibitor prolongs treatment efficacy of BRAF inhibitor in BRAF-mutated melanoma cells.

Comparable expression and phosphorylation of the retinoblastoma protein in Merkel cell polyoma virus-positive and negative Merkel cell carcinoma

Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis

Dendritic cell based antitumor vaccination: impact of functional indoleamine 2,3-dioxygenase expression.

Detection of the Merkel cell polyomavirus in the neuroendocrine component of combined Merkel cell carcinoma.

Diagnostic accuracy of a panel of immunohistochemical and molecular markers to distinguish Merkel cell carcinoma from other neuroendocrine carcinomas

Differential gene expression in apoptotic 32Dcl3 cells: induction of metallothionein.

Distinction of 2 different primary Merkel cell carcinomas in 1 patient by Merkel cell polyomavirus genome analysis.

Elucidating the mechanism of action of domatinostat (4SC-202) in cutaneous T cell lymphoma cells

Expression of Merkelcell polyomavirus (MCPyV) large T-antigen in Merkel cell carcinoma lymph node metastases predicts poor outcome.

Expression of the tetraspanins CD9, CD37, CD63, and CD151 in Merkel cell carcinoma: strong evidence for a posttranscriptional fine-tuning of CD9 gene expression

Immunogenicity of constitutively active V599EBRaf

Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy

LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression

Lack of Wnt5A expression in Merkel cell carcinoma.

Lack of correlation between IGFBP7 expression and BRAF mutational status in melanoma

MAPK-independent impairment of T-cell responses by the multikinase inhibitor sorafenib

MC polyomavirus is frequently present in Merkel cell carcinoma of European patients.

Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.

Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens.

Melanoma stem cells: targets for successful therapy?

Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression.

Merkel Cell Polyomavirus Large T Antigen is Dispensable in G2 and M-Phase to Promote Proliferation of Merkel Cell Carcinoma Cells

Merkel Cell Polyomavirus T Antigens Induce Merkel Cell-Like Differentiation in GLI1-Expressing Epithelial Cells

Merkel cell carcinoma and Merkel cell polyomavirus: evidence for hit-and-run oncogenesis

Merkel cell carcinomas infiltrated with CD33+ myeloid cells and CD8+ T cells are associated with improved outcome

Merkel cell polyomavirus status is not associated with clinical course of Merkel cell carcinoma.

Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens

Merkel cell polyomavirus-positive Merkel cell carcinoma cells do not require expression of the viral small T antigen.

Microencapsulated transplantation of allogeneic islets into specifically presensitized recipients

Microphthalmia-associated transcription factor gene amplification in metastatic melanoma is a prognostic marker for patient survival, but not a predictive marker for chemosensitivity and chemotherapy response

Microvessel density and expression of vascular endothelial growth factor and its receptors in different subtypes of primary cutaneous B-cell lymphoma

Morphologic and immunophenotypical features distinguishing Merkel cell polyomavirus-positive and negative Merkel cell carcinoma

No evidence for association of HPyV6 or HPyV7 with different skin cancers

Overexpression of the KIT/SCF in uveal melanoma does not translate into clinical efficacy of imatinib mesylate.

Phospho-ERK staining is a poor indicator of the mutational status of BRAF and NRAS in human melanoma.

Pigmentation, Melanocyte Colonization, and p53 Status in Basal Cell Carcinoma ⬇️

Production of purified alginates suitable for use in immunoisolated transplantation

RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells.

RKIP does not contribute to MAP kinase pathway silencing in the Merkel Cell Carcinoma cell line UISO.

Regulation of glycolysis by Raf protein serine/threonine kinases

Response to Shuda et al.

Response to imatinib mesylate depends on the presence of the V559A-mutated KIT oncogene

Role of matrix metalloproteinases in melanoma cell invasion

Serine 220 phosphorylation of the Merkel cell polyomavirus large T antigen crucially supports growth of Merkel cell carcinoma cells.

Significant correlation of peptidyl-prolyl isomerase overexpression in Merkel cell carcinoma with overall survival of patients

Survivin downregulation is not required for T antigen knockdown mediated cell growth inhibition in MCV infected merkel cell carcinoma cells

The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.

The TGF-β-inducible miR-23a cluster attenuates IFN-γ levels and antigen-specific cytotoxicity in human CD8⁺ T cells

The carcinogenic potential of tacrolimus ointment beyond immune suppression: a hypothesis creating case report.

The effect of resveratrol in combination with irradiation and chemotherapy: study using Merkel cell carcinoma cell lines

The identification of patient-specific mutations reveals dual pathway activation in most patients with melanoma and activated receptor tyrosine kinases in BRAF/NRAS wild-type melanomas

Transplantation of microencapsulated islets in rats: evidence for induction of fibrotic overgrowth by islet alloantigens released from microcapsules

Type I and II IFNs inhibit Merkel cell carcinoma via modulation of the Merkel cell polyomavirus T antigens.

Unique Role of Histone Methyltransferase PRDM8 in the Tumorigenesis of Virus-Negative Merkel Cell Carcinoma

VEGF-A inhibition as a potential therapeutic approach in Merkel cell carcinoma

[Immunologic isolation of transplanted islets of Langerhans: microcapsules with defined molecular limits]

[Kinase inhibitors for the therapy of malignant melanoma].

[New therapeutic approaches for solid tumors: histone deacetylase, methyltransferase and proteasome inhibitors].

p53 regulation by TRP2 is not pervasive in melanoma