Lista de obras - Bruno Guigas - Dominio Público Uruguay

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

artículo científico publicado en 2006

A 5-day high-fat, high-calorie diet impairs insulin sensitivity in healthy, young South Asian men but not in Caucasian men

scientific article published on 01 January 2014

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.

artículo científico publicado en 2012

A novel nutritional supplement prevents muscle loss and accelerates muscle mass recovery in caloric-restricted mice

artículo científico publicado en 2019

A single day of high-fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice

artículo científico publicado en 2019

A worm of one's own: how helminths modulate host adipose tissue function and metabolism

artículo científico publicado en 2015

AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.

artículo científico publicado en 2009

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

artículo científico publicado en 2012

AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside

artículo científico publicado en 2007

AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B.

artículo científico publicado en 2006

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation

scientific article published on 17 July 2018

AMPK: Lessons from transgenic and knockout animals

artículo científico publicado en 2009

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

artículo científico publicado en 2006

Assessing Mitochondrial Bioenergetics by Respirometry in Cells or Isolated Organelles

artículo científico publicado en 2018

Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators

artículo científico publicado en 2009

CD24(hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide

artículo científico publicado en 2014

Cellular and molecular mechanisms of metformin: an overview

artículo científico publicado en 2012

Chronic Intermittent Hypoxia Impairs Insulin Sensitivity but Improves Whole-Body Glucose Tolerance by Activating Skeletal Muscle AMPK.

artículo científico publicado en 2017

Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice

artículo científico publicado en 2015

Chronic treatment with olanzapine increases adiposity by changing fuel substrate and causes desensitization of the acute metabolic side effects

artículo científico publicado en 2013

Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice

artículo científico publicado en 2011

Cryopreservation of human hepatocytes alters the mitochondrial respiratory chain complex 1

artículo científico publicado en 2007

Determination of Adenine Nucleotide Concentrations in Cells and Tissues by High-Performance Liquid Chromatography

artículo científico publicado en 2018

Development of hepatic fibrosis occurs normally in AMPK-deficient mice

artículo científico publicado en 2009

Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance.

artículo científico publicado en 2018

Editorial - Parasites and metabolic diseases

artículo científico publicado en 2017

Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals

artículo científico publicado en 2013

Environmental 24-hr Cycles Are Essential for Health

artículo científico publicado en 2016

Fluid-regulatory hormone responses during cycling exercise in acute hypobaric hypoxia

artículo científico publicado en 2004

From cancer to diabetes treatment : the tumor suppressor LKB1 as a new pharmacological target

artículo científico publicado en 2006

Gene expression analysis of mTOR pathway: association with human longevity

artículo científico publicado en 2012

Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial

artículo científico publicado en 2013

Glucose 6-phosphate hydrolysis is activated by glucagon in a low temperature-sensitive manner

artículo científico publicado en 2001

Glucose availability but not changes in pancreatic hormones sensitizes hepatic AMPK activity during nutritional transition in rodents

artículo científico publicado en 2020

Helminth infections and type 2 diabetes: a cluster-randomized placebo controlled SUGARSPIN trial in Nangapanda, Flores, Indonesia

artículo científico publicado en 2015

Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice

artículo científico publicado en 2011

Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice

artículo científico publicado en 2011

High expression of thyroid hormone receptors and mitochondrial glycerol-3-phosphate dehydrogenase in the liver is linked to enhanced fatty acid oxidation in Lou/C, a rat strain resistant to obesity

artículo científico publicado en 2008

High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity

artículo científico publicado en 2010

Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice.

artículo científico publicado en 2016

Impact of Metformin and compound C on NIS expression and iodine uptake in vitro and in vivo: a role for CRE in AMPK modulation of thyroid function.

artículo científico publicado en 2013

Impact of rural-urban environment on metabolic profile and response to a 5-day high-fat diet.

artículo científico publicado en 2018

Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity

artículo científico publicado en 2015

Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production

artículo científico publicado en 2017

Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity

scientific article published on 04 December 2007

Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians

artículo científico publicado en 2017

Liver mitochondrial properties from the obesity-resistant Lou/C rat.

artículo científico publicado en 2008

Metabolic and hormonal responses to exercise in the anti-obese Lou/C rats

scientific article published on 01 August 2004

Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status

artículo científico publicado en 2011

Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study

artículo científico publicado en 2004

Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice

artículo científico publicado en 2013

Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process

artículo científico publicado en 2005

Metformin: from mechanisms of action to therapies

artículo científico publicado en 2014

Middle-aged overweight South Asian men exhibit a different metabolic adaptation to short-term energy restriction compared with Europeans

artículo científico publicado en 2014

Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses <i>In Vitro</i> Without Altering Inflammatory Disease Outcomes

artículo científico publicado en 2021

Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.

artículo científico publicado en 2007

No lack of contraction-induced AMPK activation and glucose uptake in fast-twitch muscles from adenylate kinase-1 knockout mice

artículo científico publicado en 2008

Obligatory role of membrane events in the regulatory effect of metformin on the respiratory chain function

artículo científico publicado en 2002

Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity

artículo científico publicado en 2014

Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.

artículo científico publicado en 2010

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.

artículo científico publicado en 2013

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells

artículo científico publicado en 2011

Prevention of steatohepatitis by pioglitazone: implication of adiponectin-dependent inhibition of SREBP-1c and inflammation

artículo científico publicado en 2008

Priming dendritic cells for th2 polarization: lessons learned from helminths and implications for metabolic disorders

artículo científico publicado en 2014

Proline-rich Akt substrate of 40-kDa contains a nuclear export signal.

artículo científico publicado en 2013

Rapamycin and omega-1: mTOR-dependent and -independent Th2 skewing by human dendritic cells

artículo científico publicado en 2013

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans.

artículo científico publicado en 2014

Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle

artículo científico publicado en 2007

Role of Mitochondria in the Mechanism(s) of Action of Metformin

artículo científico publicado en 2019

Régulation du métabolisme énergétique par l’AMPK

artículo científico publicado en 2006

Salsalate activates brown adipose tissue in mice

artículo científico publicado en 2014

Schistosoma haematobium infection is associated with lower serum cholesterol levels and improved lipid profile in overweight/obese individuals

artículo científico publicado en 2020

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility

artículo científico publicado en 2014

Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects.

artículo científico publicado en 2015

Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice

artículo científico publicado en 2011

Targeting AMPK: From Ancient Drugs to New Small-Molecule Activators

artículo científico publicado en 2016

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

artículo científico publicado en 2013

The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin

artículo científico publicado en 2006

The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation

scientific journal article

The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice

artículo científico publicado en 2013

The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells.

artículo científico publicado en 2010

The flavonoid silibinin decreases glucose-6-phosphate hydrolysis in perfused rat hepatocytes by an inhibitory effect on glucose-6-phosphatase

artículo científico publicado en 2007

The insulin sensitizing effect of topiramate involves KATP channel activation in the central nervous system

artículo científico publicado en 2013

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

artículo científico publicado en 2019

Lista de obras de Bruno Guigas

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

A 5-day high-fat, high-calorie diet impairs insulin sensitivity in healthy, young South Asian men but not in Caucasian men

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.

A novel nutritional supplement prevents muscle loss and accelerates muscle mass recovery in caloric-restricted mice

A single day of high-fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice

A worm of one's own: how helminths modulate host adipose tissue function and metabolism

AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside

AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B.

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation

AMPK: Lessons from transgenic and knockout animals

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

Assessing Mitochondrial Bioenergetics by Respirometry in Cells or Isolated Organelles

Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators

CD24(hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide

Cellular and molecular mechanisms of metformin: an overview

Chronic Intermittent Hypoxia Impairs Insulin Sensitivity but Improves Whole-Body Glucose Tolerance by Activating Skeletal Muscle AMPK.

Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice

Chronic treatment with olanzapine increases adiposity by changing fuel substrate and causes desensitization of the acute metabolic side effects

Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice

Cryopreservation of human hepatocytes alters the mitochondrial respiratory chain complex 1

Determination of Adenine Nucleotide Concentrations in Cells and Tissues by High-Performance Liquid Chromatography

Development of hepatic fibrosis occurs normally in AMPK-deficient mice

Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance.

Editorial - Parasites and metabolic diseases

Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals

Environmental 24-hr Cycles Are Essential for Health

Fluid-regulatory hormone responses during cycling exercise in acute hypobaric hypoxia

From cancer to diabetes treatment : the tumor suppressor LKB1 as a new pharmacological target

Gene expression analysis of mTOR pathway: association with human longevity

Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial

Glucose 6-phosphate hydrolysis is activated by glucagon in a low temperature-sensitive manner

Glucose availability but not changes in pancreatic hormones sensitizes hepatic AMPK activity during nutritional transition in rodents

Helminth infections and type 2 diabetes: a cluster-randomized placebo controlled SUGARSPIN trial in Nangapanda, Flores, Indonesia

Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice

Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice

High expression of thyroid hormone receptors and mitochondrial glycerol-3-phosphate dehydrogenase in the liver is linked to enhanced fatty acid oxidation in Lou/C, a rat strain resistant to obesity

High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity

Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice.

Impact of Metformin and compound C on NIS expression and iodine uptake in vitro and in vivo: a role for CRE in AMPK modulation of thyroid function.

Impact of rural-urban environment on metabolic profile and response to a 5-day high-fat diet.

Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity

Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production

Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity

Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians

Liver mitochondrial properties from the obesity-resistant Lou/C rat.

Metabolic and hormonal responses to exercise in the anti-obese Lou/C rats

Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status

Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study

Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice

Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process

Metformin: from mechanisms of action to therapies

Middle-aged overweight South Asian men exhibit a different metabolic adaptation to short-term energy restriction compared with Europeans

Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses <i>In Vitro</i> Without Altering Inflammatory Disease Outcomes

Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.

No lack of contraction-induced AMPK activation and glucose uptake in fast-twitch muscles from adenylate kinase-1 knockout mice

Obligatory role of membrane events in the regulatory effect of metformin on the respiratory chain function

Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity

Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells

Prevention of steatohepatitis by pioglitazone: implication of adiponectin-dependent inhibition of SREBP-1c and inflammation

Priming dendritic cells for th2 polarization: lessons learned from helminths and implications for metabolic disorders

Proline-rich Akt substrate of 40-kDa contains a nuclear export signal.

Rapamycin and omega-1: mTOR-dependent and -independent Th2 skewing by human dendritic cells

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans.

Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle

Role of Mitochondria in the Mechanism(s) of Action of Metformin

Régulation du métabolisme énergétique par l’AMPK

Salsalate activates brown adipose tissue in mice

Schistosoma haematobium infection is associated with lower serum cholesterol levels and improved lipid profile in overweight/obese individuals

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility

Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects.

Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice

Targeting AMPK: From Ancient Drugs to New Small-Molecule Activators

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin

The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation