Lista de obras - Cristina Rodríguez-Antona

A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma.

artículo científico publicado en 2018

A Prospective Observational Study for Assessment and Outcome Association of Circulating Endothelial Cells in Clear Cell Renal Cell Carcinoma Patients Who Show Initial Benefit from First-line Treatment. The CIRCLES (CIRCuLating Endothelial cellS) Stu

artículo científico publicado en 2016

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A novel polymorphic cytochrome P450 formed by splicing of CYP3A7 and the pseudogene CYP3AP1.

artículo científico publicado en 2005

Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation.

artículo científico publicado en 2018

Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels.

artículo científico publicado en 2010

Association between SLC19A1 Gene Polymorphism and High Dose Methotrexate Toxicity in Childhood Acute Lymphoblastic Leukaemia and Non Hodgkin Malignant Lymphoma: Introducing a Haplotype based Approach

artículo científico publicado en 2017

Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma.

artículo científico publicado en 2015

Biallelic TSC2 Mutations in a Patient With Chromophobe Renal Cell Carcinoma Showing Extraordinary Response to Temsirolimus

artículo científico publicado en 2018

CYP2D6 genotyping for psychiatric patients treated with risperidone: considerations for cost-effectiveness studies

artículo científico publicado en 2009

CYP3A5 and ABCB1 polymorphisms as predictors for sunitinib outcome in metastatic renal cell carcinoma.

artículo científico publicado en 2015

Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism

artículo científico publicado en 2007

Constitutional genetic variants as predictors of antiangiogenic therapy outcome in renal cell carcinoma.

artículo científico publicado en 2012

Cytochrome P-450 mRNA Expression in Human Liver and Its Relationship with Enzyme Activity

article

Cytochrome P450 3A5 is highly expressed in normal prostate cells but absent in prostate cancer

artículo científico publicado en 2007

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

artículo científico publicado en 2002

Cytochrome P450 pharmacogenetics and cancer.

artículo científico publicado en 2006

DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers

artículo científico publicado en 2015

Deep sequencing reveals microRNAs predictive of antiangiogenic drug response

artículo científico publicado en 2016

Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene

artículo científico publicado en 2012

Description of the EuroTARGET cohort: A European collaborative project on TArgeted therapy in renal cell cancer-GEnetic- and tumor-related biomarkers for response and toxicity.

artículo científico publicado en 2017

Detection of the first gross CDC73 germline deletion in an HPT-JT syndrome family.

artículo científico publicado en 2011

Determination of CYP2D6 gene copy number by multiplex polymerase chain reaction analysis

artículo científico publicado en 2009

Development and validation of the gene-expression Predictor of high-grade-serous Ovarian carcinoma molecular subTYPE (PrOTYPE)

scientific article published on 17 June 2020

Differential gene expression of medullary thyroid carcinoma reveals specific markers associated with genetic conditions

artículo científico publicado en 2012

Evaluation of KDR rs34231037 as a predictor of sunitinib efficacy in patients with metastatic renal cell carcinoma.

artículo científico publicado en 2017

Exceptional Response to Temsirolimus in a Metastatic Clear Cell Renal Cell Carcinoma With an Early Novel MTOR-Activating Mutation

artículo científico publicado en 2017

Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma

artículo científico publicado en 2011

Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas

artículo científico publicado en 2007

Functional and in silico assessment of MAX variants of unknown significance

artículo científico publicado en 2015

Gain-of-function mutations in DNMT3A in patients with paraganglioma

artículo científico publicado en 2018

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

artículo científico publicado en 2018

Genetic polymorphisms of SCN9A are associated with oxaliplatin-induced neuropathy

artículo científico publicado en 2017

Genetic variation in the SLC19A1 gene and methotrexate toxicity in rheumatoid arthritis patients.

artículo científico publicado en 2012

Genetics of pheochromocytoma and paraganglioma in Spanish patients.

artículo científico publicado en 2009

Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy

scientific journal article

Gross SDHB deletions in patients with paraganglioma detected by multiplex PCR: a possible hot spot?

artículo científico publicado en 2006

Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity.

artículo científico publicado en 2012

Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing

artículo científico publicado en 2019

IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma

artículo científico publicado en 2015

Identification and phenotype characterization of two CYP3A haplotypes causing different enzymatic capacity in fetal livers

artículo científico publicado en 2005

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

artículo científico publicado en 2017

Identification of candidate SNPs for drug induced toxicity from differentially expressed genes in associated tissues

artículo científico publicado en 2012

Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma

artículo científico publicado en 2014

Impact of chemotherapy on telomere length in sporadic and familial breast cancer patients

artículo científico publicado en 2014

Impact of genetic polymorphisms in CYP2C8 and rosiglitazone intake on the urinary excretion of dihydroxyeicosatrienoic acids

artículo científico publicado en 2008

Improving pharmacovigilance in Europe: TPMT genotyping and phenotyping in the UK and Spain

artículo científico publicado en 2009

Influence of RET mutations on the expression of tyrosine kinases in medullary thyroid carcinoma

artículo científico publicado en 2013

Influence of donor liver CYP3A4*20 loss-of-function genotype on tacrolimus pharmacokinetics in transplanted patients.

artículo científico publicado en 2017

Integrative analysis of miRNA and mRNA expression profiles in pheochromocytoma and paraganglioma identifies genotype-specific markers and potentially regulated pathways

artículo científico publicado en 2013

Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix

artículo científico publicado en 1998

Loss of the actin regulator HSPC300 results in clear cell renal cell carcinoma protection in Von Hippel-Lindau patients

artículo científico publicado en 2007

Meta-analysis on the association of VEGFR1 genetic variants with sunitinib outcome in metastatic renal cell carcinoma patients

artículo científico publicado en 2016

Microtubule-Targeting Drugs and Personalization of Cancer Treatment ⬇️

artículo científico publicado el 1 de abril de 2011

Molecular characterisation of a common SDHB deletion in paraganglioma patients.

artículo científico publicado en 2007

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

artículo científico publicado en 2017

Overexpression and activation of EGFR and VEGFR2 in medullary thyroid carcinomas is related to metastasis.

artículo científico publicado en 2010

Oxaliplatin induced-neuropathy in digestive tumors

artículo científico

PTEN expression and mutations in TSC1, TSC2 and MTOR are associated with response to rapalogs in patients with renal cell carcinoma

artículo científico publicado en 2019

Pazopanib in pretreated advanced neuroendocrine tumors: a phase II, open-label trial of the Spanish Task Force Group for Neuroendocrine Tumors (GETNE).

artículo científico publicado en 2015

Pharmacogenomic biomarkers for personalized cancer treatment.

artículo científico publicado en 2015

Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles

artículo científico publicado en 2005

PheoSeq: A Targeted Next-Generation Sequencing Assay for Pheochromocytoma and Paraganglioma Diagnostics

artículo científico publicado en 2017

Polymorphisms associated with everolimus pharmacokinetics, toxicity and survival in metastatic breast cancer

artículo científico publicado en 2017

Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity

artículo científico publicado en 2010

Progress in pharmacogenetics: consortiums and new strategies

artículo científico publicado en 2016

Prospective study assessing hypoxia-related proteins as markers for the outcome of treatment with sunitinib in advanced clear-cell renal cell carcinoma.

artículo científico publicado en 2013

Quantitative RT-PCR Measurement of Human Cytochrome P-450s: Application to Drug Induction Studies

artículo científico publicado en 2000

Rationalization of genetic testing in patients with apparently sporadic pheochromocytoma/paraganglioma.

artículo científico publicado en 2009

Recommendations for somatic and germline genetic testing of single pheochromocytoma and paraganglioma based on findings from a series of 329 patients.

artículo científico publicado en 2015

Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy.

artículo científico publicado en 2012

Renal carcinoma pharmacogenomics and predictors of response: Steps toward treatment individualization.

artículo científico

Replication of Genetic Polymorphisms Reported to Be Associated with Taxane-Related Sensory Neuropathy in Patients with Early Breast Cancer Treated with Paclitaxel--letter.

artículo científico publicado en 2015

Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas

artículo científico publicado en 2010

Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients

scientific article published on 16 July 2018

Role of cytochrome P450 2C83 (CYP2C83) in paclitaxel metabolism and paclitaxel-induced neurotoxicity.

artículo científico publicado en 2015

SDHC mutation in an elderly patient without familial antecedents.

artículo científico publicado en 2008

SNPs associated with activity and toxicity of cabazitaxel in patients with advanced urothelial cell carcinoma.

artículo científico publicado en 2016

Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study

article

Sunitinib and Evofosfamide (TH-302) in Systemic Treatment-Naïve Patients with Grade 1/2 Metastatic Pancreatic Neuroendocrine Tumors: The GETNE-1408 Trial

artículo científico publicado en 2021

Sunitinib-induced hypertension in CYP3A4 rs4646437 A-allele carriers with metastatic renal cell carcinoma.

artículo científico publicado en 2016

Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.

artículo científico publicado en 2016

The hematopoietic-specific beta1-tubulin is naturally resistant to 2-methoxyestradiol and protects patients from drug-induced myelosuppression

artículo científico publicado en 2009

The miR-200 family controls -tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients

artículo científico publicado en 2010

The role of pharmacogenetics and pharmacogenomics in 21st-century medicine: state of the art and new challenges discussed in the VII Conference of the Spanish Pharmacogenetics and Pharmacogenomics Society (SEFF)

artículo científico publicado en 2016

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors

artículo científico publicado en 2009

Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma

artículo científico publicado en 2003

Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis

artículo científico publicado en 2013

Tumoral and tissue-specific expression of the major human beta-tubulin isotypes

artículo científico publicado en 2010

VEGF, VEGFR3, and PDGFRB protein expression is influenced by RAS mutations in medullary thyroid carcinoma.

artículo científico publicado en 2014

Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.

artículo científico publicado en 2015

mTOR Pathway Mutations and Response to Rapalogs in RCC-Letter.

artículo científico publicado en 2017

Lista de obras de Cristina Rodríguez-Antona

A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma.

A Prospective Observational Study for Assessment and Outcome Association of Circulating Endothelial Cells in Clear Cell Renal Cell Carcinoma Patients Who Show Initial Benefit from First-line Treatment. The CIRCLES (CIRCuLating Endothelial cellS) Stu

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

A novel polymorphic cytochrome P450 formed by splicing of CYP3A7 and the pseudogene CYP3AP1.

Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation.

Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels.

Association between SLC19A1 Gene Polymorphism and High Dose Methotrexate Toxicity in Childhood Acute Lymphoblastic Leukaemia and Non Hodgkin Malignant Lymphoma: Introducing a Haplotype based Approach

Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma.

Biallelic TSC2 Mutations in a Patient With Chromophobe Renal Cell Carcinoma Showing Extraordinary Response to Temsirolimus

CYP2D6 genotyping for psychiatric patients treated with risperidone: considerations for cost-effectiveness studies

CYP3A5 and ABCB1 polymorphisms as predictors for sunitinib outcome in metastatic renal cell carcinoma.

Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism

Constitutional genetic variants as predictors of antiangiogenic therapy outcome in renal cell carcinoma.

Cytochrome P-450 mRNA Expression in Human Liver and Its Relationship with Enzyme Activity

Cytochrome P450 3A5 is highly expressed in normal prostate cells but absent in prostate cancer

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

Cytochrome P450 pharmacogenetics and cancer.

DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers

Deep sequencing reveals microRNAs predictive of antiangiogenic drug response

Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene

Description of the EuroTARGET cohort: A European collaborative project on TArgeted therapy in renal cell cancer-GEnetic- and tumor-related biomarkers for response and toxicity.

Detection of the first gross CDC73 germline deletion in an HPT-JT syndrome family.

Determination of CYP2D6 gene copy number by multiplex polymerase chain reaction analysis

Development and validation of the gene-expression Predictor of high-grade-serous Ovarian carcinoma molecular subTYPE (PrOTYPE)

Differential gene expression of medullary thyroid carcinoma reveals specific markers associated with genetic conditions

Evaluation of KDR rs34231037 as a predictor of sunitinib efficacy in patients with metastatic renal cell carcinoma.

Exceptional Response to Temsirolimus in a Metastatic Clear Cell Renal Cell Carcinoma With an Early Novel MTOR-Activating Mutation

Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma

Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas

Functional and in silico assessment of MAX variants of unknown significance

Gain-of-function mutations in DNMT3A in patients with paraganglioma

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

Genetic polymorphisms of SCN9A are associated with oxaliplatin-induced neuropathy

Genetic variation in the SLC19A1 gene and methotrexate toxicity in rheumatoid arthritis patients.

Genetics of pheochromocytoma and paraganglioma in Spanish patients.

Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy

Gross SDHB deletions in patients with paraganglioma detected by multiplex PCR: a possible hot spot?

Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity.

Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing

IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma

Identification and phenotype characterization of two CYP3A haplotypes causing different enzymatic capacity in fetal livers

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Identification of candidate SNPs for drug induced toxicity from differentially expressed genes in associated tissues

Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma

Impact of chemotherapy on telomere length in sporadic and familial breast cancer patients

Impact of genetic polymorphisms in CYP2C8 and rosiglitazone intake on the urinary excretion of dihydroxyeicosatrienoic acids

Improving pharmacovigilance in Europe: TPMT genotyping and phenotyping in the UK and Spain

Influence of RET mutations on the expression of tyrosine kinases in medullary thyroid carcinoma

Influence of donor liver CYP3A4*20 loss-of-function genotype on tacrolimus pharmacokinetics in transplanted patients.

Integrative analysis of miRNA and mRNA expression profiles in pheochromocytoma and paraganglioma identifies genotype-specific markers and potentially regulated pathways

Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix

Loss of the actin regulator HSPC300 results in clear cell renal cell carcinoma protection in Von Hippel-Lindau patients

Meta-analysis on the association of VEGFR1 genetic variants with sunitinib outcome in metastatic renal cell carcinoma patients

Microtubule-Targeting Drugs and Personalization of Cancer Treatment ⬇️

Molecular characterisation of a common SDHB deletion in paraganglioma patients.

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

Overexpression and activation of EGFR and VEGFR2 in medullary thyroid carcinomas is related to metastasis.

Oxaliplatin induced-neuropathy in digestive tumors

PTEN expression and mutations in TSC1, TSC2 and MTOR are associated with response to rapalogs in patients with renal cell carcinoma

Pazopanib in pretreated advanced neuroendocrine tumors: a phase II, open-label trial of the Spanish Task Force Group for Neuroendocrine Tumors (GETNE).

Pharmacogenomic biomarkers for personalized cancer treatment.

Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles

PheoSeq: A Targeted Next-Generation Sequencing Assay for Pheochromocytoma and Paraganglioma Diagnostics

Polymorphisms associated with everolimus pharmacokinetics, toxicity and survival in metastatic breast cancer

Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity

Progress in pharmacogenetics: consortiums and new strategies

Prospective study assessing hypoxia-related proteins as markers for the outcome of treatment with sunitinib in advanced clear-cell renal cell carcinoma.

Quantitative RT-PCR Measurement of Human Cytochrome P-450s: Application to Drug Induction Studies

Rationalization of genetic testing in patients with apparently sporadic pheochromocytoma/paraganglioma.

Recommendations for somatic and germline genetic testing of single pheochromocytoma and paraganglioma based on findings from a series of 329 patients.

Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy.

Renal carcinoma pharmacogenomics and predictors of response: Steps toward treatment individualization.

Replication of Genetic Polymorphisms Reported to Be Associated with Taxane-Related Sensory Neuropathy in Patients with Early Breast Cancer Treated with Paclitaxel--letter.

Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas

Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients

Role of cytochrome P450 2C8*3 (CYP2C8*3) in paclitaxel metabolism and paclitaxel-induced neurotoxicity.

SDHC mutation in an elderly patient without familial antecedents.

SNPs associated with activity and toxicity of cabazitaxel in patients with advanced urothelial cell carcinoma.

Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study

Role of cytochrome P450 2C83 (CYP2C83) in paclitaxel metabolism and paclitaxel-induced neurotoxicity.