Filtros de búsqueda

Lista de obras de Nobuyuki Okamura

18F-Labeled 2-Arylquinoline Derivatives for Tau Imaging: Chemical, Radiochemical, Biological and Clinical Features.

artículo científico publicado en 2016

18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease

artículo científico publicado en 2011

18F-THK5351 PET Imaging in Nonfluent-Agrammatic Variant Primary Progressive Aphasia

scientific article published on 01 September 2018

18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease.

artículo científico publicado en 2015

2-(2-[2-Dimethylaminothiazol-5-yl]ethenyl)-6- (2-[fluoro]ethoxy)benzoxazole: a novel PET agent for in vivo detection of dense amyloid plaques in Alzheimer's disease patients

artículo científico publicado en 2007

A 18F-labeled BF-227 derivative as a potential radioligand for imaging dense amyloid plaques by positron emission tomography.

artículo científico publicado en 2013

A modified method of 3D-SSP analysis for amyloid PET imaging using [¹¹C]BF-227.

artículo científico publicado en 2011

A novel imaging probe for in vivo detection of neuritic and diffuse amyloid plaques in the brain.

artículo científico publicado en 2004

Advances in molecular imaging for the diagnosis of dementia

artículo científico publicado en 2009

Advances in the development of tau PET radiotracers and their clinical applications

artículo científico publicado en 2016

Amyloid PET in mild cognitive impairment and Alzheimer's disease with BF-227: comparison to FDG-PET.

artículo científico publicado en 2009

Amyloid and tau imaging, its present and future

artículo científico publicado en 2015

Amyloid deposits and response to shunt surgery in idiopathic normal-pressure hydrocephalus.

artículo científico publicado en 2015

Analysis of early phase [11C]BF-227 PET, and its application for anatomical standardization of late-phase images for 3D-SSP analysis.

artículo científico publicado en 2014

Applied multimodal diagnostics in a case of presenile dementia.

artículo científico publicado en 2016

Arg(184)His mutant GTP cyclohydrolase I, causing recessive hyperphenylalaninemia, is responsible for dopa-responsive dystonia with parkinsonism: a case report

artículo científico publicado en 2004

Assessing THK523 selectivity for tau deposits in Alzheimer's disease and non-Alzheimer's disease tauopathies.

scientific article published on 26 February 2014

Benefits of combining donepezil plus traditional Japanese herbal medicine on cognition and brain perfusion in Alzheimer's disease: a 12-week observer-blind, donepezil monotherapy controlled trial

artículo científico publicado en 2006

Biomarkers in subjects with amnestic mild cognitive impairment

artículo científico publicado en 2003

Blocking histamine H(1) improves learning and mnemonic dysfunction in mice with social isolation plus repeated methamphetamine injection.

artículo científico publicado en 2008

Brain accumulation of amyloid β protein visualized by positron emission tomography and BF-227 in Alzheimer's disease patients with or without diabetes mellitus

artículo científico publicado en 2012

Brain activity associated with dual-task management differs depending on the combinations of response modalities.

artículo científico publicado en 2007

Brain histamine H1 receptor occupancy of loratadine measured by positron emission topography: comparison of H1 receptor occupancy and proportional impairment ratio

artículo científico publicado en 2011

CSF phosphorylated tau protein and mild cognitive impairment: a prospective study

artículo científico publicado en 2000

Cardiac positron-emission tomography images with an amyloid-specific tracer in familial transthyretin-related systemic amyloidosis

artículo científico publicado en 2012

Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET.

artículo científico publicado en 2017

Cerebrospinal fluid amyloid beta(1-42) levels in the mild cognitive impairment stage of Alzheimer's disease

artículo científico publicado en 2001

Cerebrospinal fluid levels of amyloid beta-peptide1-42, but not tau have positive correlation with brain glucose metabolism in humans

artículo científico publicado en 1999

Characterization of the radiolabeled metabolite of tau PET tracer 18F-THK5351.

artículo científico publicado en 2016

Cholinergic deficit and response to donepezil therapy in Parkinson's disease with dementia

artículo científico publicado en 2012

Classification of dementias

artículo científico publicado en 2003

Clinical and biomarker investigation of a patient with a novel presenilin-1 mutation (A431V) in the mild cognitive impairment stage of Alzheimer's disease

artículo científico publicado en 2002

Combined Analysis of CSF Tau Levels and [(123)I]Iodoamphetamine SPECT in Mild Cognitive Impairment: Implications for a Novel Predictor of Alzheimer's Disease

artículo científico publicado en 2002

Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology

artículo científico publicado en 2018

Comparison of the binding characteristics of [18F]THK-523 and other amyloid imaging tracers to Alzheimer's disease pathology

artículo científico publicado en 2012

Comparison study of amyloid PET and voxel-based morphometry analysis in mild cognitive impairment and Alzheimer's disease.

artículo científico publicado en 2009

Cortical laminar binding of PET amyloid and tau tracers in Alzheimer disease

artículo científico publicado en 2015

Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging

artículo científico publicado en 2012

Discrete cortical regions associated with the musical beauty of major and minor chords.

artículo científico publicado en 2008

Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer's Disease Patients Measured Using [18F] THK-5351

artículo científico publicado en 2016

Effects of a sedative antihistamine, D-chlorpheniramine, on regional cerebral perfusion and performance during simulated car driving

artículo científico publicado en 2008

Effects of histamine H(3) antagonists and donepezil on learning and mnemonic deficits induced by pentylenetetrazol kindling in weanling mice.

artículo científico publicado en 2005

Erratum to: Characterization of the radiolabeled metabolite of tau PET tracer 18F-THK5351

artículo científico publicado en 2017

Evaluation of the biodistribution and radiation dosimetry of the 18F-labelled amyloid imaging probe [18F]FACT in humans.

artículo científico publicado en 2013

Geriatric medicine, Japanese Alzheimer's disease neuroimaging initiative and biomarker development

artículo científico publicado en 2010

Glucose hypometabolism and neuropathological correlates in brains of dementia with Lewy bodies

artículo científico publicado en 2000

Greater responsiveness to donepezil in Alzheimer patients with higher levels of acetylcholinesterase based on attention task scores and a donepezil PET study.

artículo científico publicado en 2012

Histamine H(1) receptors in patients with Alzheimer's disease assessed by positron emission tomography

artículo científico publicado en 2000

IgLON5: A case with predominant cerebellar tau deposits and leptomeningeal inflammation

artículo científico publicado en 2018

Imaging Alzheimer's Disease: The Evolution of Biomarkers

Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls ⬇️

artículo científico publicado el 18 de septiembre de 2013

Imaging of amyloid deposition in human brain using positron emission tomography and [18F]FACT: comparison with [11C]PIB.

artículo científico publicado en 2014

In vitro characterisation of BF227 binding to alpha-synuclein/Lewy bodies.

artículo científico publicado en 2009

In vivo assessment of vesicular monoamine transporter type 2 in dementia with lewy bodies and Alzheimer disease.

artículo científico publicado en 2011

In vivo detection of amyloid plaques in the mouse brain using the near-infrared fluorescence probe THK-265

artículo científico publicado en 2011

In vivo evaluation of a novel tau imaging tracer for Alzheimer's disease.

artículo científico

In vivo imaging of amyloid plaques in the brain

artículo científico publicado en 2004

In vivo measurement of vesicular monoamine transporter type 2 density in Parkinson disease with (18)F-AV-133

artículo científico publicado en 2010

In vivo tau imaging: obstacles and progress

artículo científico publicado en 2014

In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET.

artículo científico publicado en 2016

In-vivo imaging of amyloid plaques

artículo científico publicado en 2008

Influence of anesthesia on brain distribution of [(11)C]methamphetamine in monkeys in positron emission tomography (PET) study.

artículo científico publicado en 2001

Introduction and overview of the special issue "Brain imaging and aging": The new era of neuroimaging in aging research.

artículo científico publicado en 2016

Longitudinal Assessment of Tau Pathology in Patients with Alzheimer's Disease Using [18F]THK-5117 Positron Emission Tomography.

artículo científico publicado en 2015

Mechanism of the histamine H(3) receptor-mediated increase in exploratory locomotor activity and anxiety-like behaviours in mice

artículo científico publicado en 2014

Methamphetamine- and 3,4-methylenedioxymethamphetamine-induced behavioral changes in histamine H3-receptor knockout mice

artículo científico publicado en 2009

Neural correlates of perceptual difference between itching and pain: a human fMRI study.

artículo científico publicado en 2007

Neuroanatomical correlates of low body weight in Alzheimer's disease: a PET study

artículo científico publicado en 2002

Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine

artículo científico publicado en 2001

Next-day residual sedative effect after nighttime administration of an over-the-counter antihistamine sleep aid, diphenhydramine, measured by positron emission tomography.

artículo científico publicado en 2010

Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.

artículo científico publicado en 2014

Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease

artículo científico publicado en 2013

PET Imaging of Astrogliosis and Tau Facilitates Diagnosis of Parkinsonian Syndromes

scientific article published on 11 September 2019

Pathobiology of Alzheimer's disease and biomarker development.

artículo científico publicado en 2010

Perfusion-Phase [18F]THK5351 Tau-PET Imaging as a Surrogate Marker for Neurodegeneration

scientific article published on 28 September 2017

Pitfalls of voxel-based amyloid PET analyses for diagnosis of Alzheimer's disease: artifacts due to non-specific uptake in the white matter and the skull.

artículo científico publicado en 2014

Positron emission tomography evaluation of sedative properties of antihistamines ⬇️

artículo científico publicado el 27 de abril de 2011

Preclinical Evaluation of [(18)F]THK-5105 Enantiomers: Effects of Chirality on Its Effectiveness as a Tau Imaging Radiotracer.

artículo científico publicado en 2015

Quantitative analysis of donepezil binding to acetylcholinesterase using positron emission tomography and [5-(11)C-methoxy]donepezil

artículo científico publicado en 2009

Quantitative evaluation of tau PET tracers F-THK5351 and F-AV-1451 in Alzheimer's disease with standardized uptake value peak-alignment (SUVP) normalization

scholarly article by Jingyun Chen et al published July 2018 in European Journal of Nuclear Medicine and Molecular Imaging

Quantitative kinetic analysis of PET amyloid imaging agents [(11)C]BF227 and [(18)F]FACT in human brain.

artículo científico publicado en 2015

Quinoline and benzimidazole derivatives: candidate probes for in vivo imaging of tau pathology in Alzheimer's disease.

artículo científico publicado en 2005

Recent advances in the development of amyloid imaging agents.

artículo científico publicado en 2007

Relationship between effects of alcohol on psychomotor performances and blood alcohol concentrations

scientific article published on 01 July 2000

Roles of hypothalamic subgroup histamine and orexin neurons on behavioral responses to sleep deprivation induced by the treadmill method in adolescent rats.

artículo científico publicado en 2010

Roles of the histaminergic neurotransmission on methamphetamine-induced locomotor sensitization and reward: a study of receptors gene knockout mice.

artículo científico publicado en 2009

Serum cholesterol and cerebrospinal fluid amyloid beta protein in Alzheimer's disease

artículo científico publicado en 2001

Sleep patterns and mortality among elderly patients in a geriatric hospital.

artículo científico publicado en 2000

Small-Animal PET Imaging of Tau Pathology with 18F-THK5117 in 2 Transgenic Mouse Models

artículo científico publicado en 2016

Structure-Activity Relationship of 2-Arylquinolines as PET Imaging Tracers for Tau Pathology in Alzheimer Disease

artículo científico publicado en 2015

Styrylbenzoxazole derivatives for in vivo imaging of amyloid plaques in the brain.

artículo científico publicado en 2004

Synthesis and Characterization of ¹⁸F-Interleukin-8 Using a Cell-Free Translation System and 4-¹⁸F-Fluoro-L-Proline.

artículo científico publicado en 2016

Synthesis and preliminary evaluation of 2-arylhydroxyquinoline derivatives for tau imaging.

artículo científico publicado en 2013

Synthesis of [11C]interleukin 8 using a cell-free translation system and L-[11C]methionine

artículo científico publicado en 2011

Tau PET imaging in Alzheimer's disease

artículo científico publicado en 2014

Tau imaging in the study of ageing, Alzheimer's disease, and other neurodegenerative conditions.

artículo científico

Tau imaging with [18 F]THK-5351 in progressive supranuclear palsy

artículo científico publicado en 2016

The development and validation of tau PET tracers: current status and future directions

article

The effects of a sedative antihistamine, d-chlorpheniramine, on visuomotor spatial discrimination and regional brain activity as measured by positron emission tomography (PET).

artículo científico publicado en 2002

The neural correlates of driving performance identified using positron emission tomography.

artículo científico publicado en 2004

Untangling tau imaging

artículo científico publicado en 2016

Use of a benzimidazole derivative BF-188 in fluorescence multispectral imaging for selective visualization of tau protein fibrils in the Alzheimer's disease brain.

artículo científico publicado en 2014

Voxel-based analysis of amyloid positron emission tomography probe [C]BF-227 uptake in mild cognitive impairment and alzheimer's disease.

artículo científico publicado en 2010

[(18)F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer's disease.

artículo científico publicado en 2015

[18F]-THK5351 PET Correlates with Topology and Symptom Severity in Progressive Supranuclear Palsy.

artículo científico publicado en 2017

[18F]FDG-PET study in dementia with Lewy bodies and Alzheimer's disease

artículo científico publicado en 2001

[Molecular PET imaging for in vivo detection of amyloid in the human brain]

artículo científico publicado en 2009

[Molecular imaging techniques for research on brain function using PET]

artículo científico publicado en 2005

[¹⁸F]THK5351 PET Imaging in Patients with Mild Cognitive Impairment

artículo científico publicado en 2020

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda