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Lista de obras de Marian Ludgate

A luminescent bioassay for thyroid blocking antibodies.

artículo científico publicado en 2001

A new form of familial multi-nodular goitre with progression to differentiated thyroid cancer

artículo científico publicado en 2006

A novel thyrotropin receptor mutation in an infant with severe thyrotoxicosis

artículo científico publicado en 1999

Adipogenesis in thyroid eye disease

artículo científico publicado en 2000

Adipose thyrotrophin receptor expression is elevated in Graves' and thyroid eye diseases ex vivo and indicates adipogenesis in progress in vivo

artículo científico publicado en 2003

Adipose tissue depot-specific differences in the regulation of hyaluronan production of relevance to Graves' orbitopathy.

artículo científico publicado en 2011

Altered tear composition in smokers and patients with graves ophthalmopathy

artículo científico publicado en 2006

An InDel in Phospholipase-C-B-1 Is Linked with Euthyroid Multinodular Goiter

artículo científico publicado en 2018

An amphotropic retroviral vector expressing a mutant gsp oncogene: effects on human thyroid cells in vitro

artículo científico publicado en 1997

Analysis of T cell subsets in Graves' disease: alterations associated with carbimazole

artículo científico publicado en 1984

Analysis of extraocular muscle-infiltrating T cells in thyroid-associated ophthalmopathy (TAO)

artículo científico publicado el 1 de agosto de 1997

Analysis of sequence and structure homologies between thyroglobulin and acetylcholinesterase: possible functional and clinical significance

scientific article published on 01 May 1986

Animal model of thyroid-associated orbitopathy.

artículo científico publicado en 1999

Animal models of Graves' disease

artículo científico publicado en 2000

Animal models of thyroid-associated ophthalmopathy

artículo científico publicado en 2002

Antibodies against 1D, a recombinant 64-kDa membrane protein, are associated with ophthalmopathy in patients with thyroid autoimmunity.

artículo científico publicado en 1994

Antibodies in the serum of patients with autoimmune thyroid disorders react with a recombinant 98 amino acid fragment of a full length 64 kDa eye muscle membrane protein which is also expressed in the thyroid

artículo científico publicado en 1992

Antibodies reactive with an intracellular epitope of a recombinant 64 kDa thyroid and eye muscle protein in patients with thyroid autoimmunity and ophthalmopathy

scientific article published on 01 December 1993

Antibodies to human thyroid peroxidase in autoimmune thyroid disease: studies with a cloned recombinant complementary deoxyribonucleic acid epitope

artículo científico publicado en 1989

Apoptosis in autoimmune and non-autoimmune thyroid disease

artículo científico publicado en 1997

Association of FOXE1 polyalanine repeat region with papillary thyroid cancer

artículo científico publicado en 2012

Autoimmunity and thyroid growth: methods, concepts and misconceptions

scientific article published on 01 January 1987

Back to the Drawing Board for Antigens in Endocrine Ophthalmopathy?

artículo científico publicado el 1 de enero de 1993

Binding assay for thyrotropin receptor autoantibodies using the recombinant receptor protein

artículo científico publicado el 1 de diciembre de 1992

Biological activity of activating thyroid-stimulating hormone receptor mutants depends on the cellular context

artículo científico publicado en 2003

Biological activity of activating thyrotrophin receptor mutants: modulation by iodide.

artículo científico publicado en 2005

Biological effects of thyrotropin receptor activation on human orbital preadipocytes

artículo científico publicado en 2006

Brown fat and obesity: the next big thing?

artículo científico publicado en 2011

CATS II Long-term Anthropometric and Metabolic Effects of Maternal Sub-optimal Thyroid Function in Offspring and Mothers

artículo científico publicado en 2020

Characterisation of adipocyte-derived extracellular vesicles released pre- and post-adipogenesis

artículo científico publicado en 2015

Characterization of monoclonal antibodies to the human thyrotropin receptor

artículo científico publicado el 1 de febrero de 1992

Cloning and sequencing of a novel 64-kDa autoantigen recognized by patients with autoimmune thyroid disease

artículo científico publicado en 1991

Cloning of candidate autoantigen carboxypeptidase H from a human islet library: sequence identity with human brain CPH

artículo científico publicado en 1996

Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies

artículo científico publicado en 1989

Combining micro-RNA and protein sequencing to detect robust biomarkers for Graves' disease and orbitopathy.

artículo científico publicado en 2018

Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid.

artículo científico publicado en 2011

Complement component C9 in Graves' disease

artículo científico publicado en 1986

Contrasting effects of activating mutations of GalphaS and the thyrotropin receptor on proliferation and differentiation of thyroid follicular cells.

artículo científico publicado en 1999

Controlled Antenatal Thyroid Screening II: Effect of Treating Maternal Suboptimal Thyroid Function on Child Behavior

scientific article published on 01 March 2020

Controlled Antenatal Thyroid Screening II: effect of treating maternal sub-optimal thyroid function on child cognition

artículo científico publicado en 2018

Copy number variations and clinical outcome in atypical spitz tumors

artículo científico publicado en 2011

Current evidence for and against the TSH receptor being the common antigen in Graves' disease and thyroid associated ophthalmopathy

artículo científico publicado el 1 de junio de 1995

Cyclosporin improves Graves' ophthalmopathy

scientific article published on 01 August 1983

Definition, at the molecular level, of a thyroglobulin-acetylcholinesterase shared epitope: study of its pathophysiological significance in patients with Graves' ophthalmopathy

artículo científico publicado en 1989

Dehydroepiandrosterone (DHEA) treatment in vitro inhibits adipogenesis in human omental but not subcutaneous adipose tissue.

artículo científico publicado en 2010

Demonstration of immunoglobulin G, A, and E autoantibodies to the human thyrotropin receptor using flow cytometry

artículo científico publicado en 2002

Demonstration of reduced in vivo surface expression of activating mutant thyrotrophin receptors in thyroid sections

artículo científico publicado en 2002

Demonstration of the existence of the alternatively spliced form of thyroid peroxidase in normal thyroid

artículo científico publicado en 1991

Dermatoscopic vascular patterns in cutaneous Merkel cell carcinoma

artículo científico publicado en 2011

Detection of antibodies blocking thyrotropin effect using Chinese hamster ovary cells transfected with the cloned human TSH receptor.

artículo científico publicado en 1994

Detection of thyroid-stimulating antibody using Chinese hamster ovary cells transfected with cloned human thyrotropin receptor.

artículo científico publicado en 1993

Development of a luminescent bioassay for thyroid stimulating antibodies

scientific article published on 01 January 1999

Development of an animal model of autoimmune thyroid eye disease

artículo científico publicado en 1999

Distinctive Features of Orbital Adipose Tissue (OAT) in Graves' Orbitopathy

scientific article published on 30 November 2020

Does thyroid peroxidase provide an antigenic link between thyroid autoimmunity and breast cancer?

artículo científico publicado en 2013

Early changes in thyroid-stimulating antibody activity following radioiodine therapy

artículo científico publicado en 2003

Effect of iodine on early stage thyroid autonomy.

artículo científico publicado en 2010

Effect of lithium carbonate therapy on thyroid immune status in manic depressive patients: a prospective study

artículo científico publicado en 1986

Effect of tri-iodothyronine on normal human lymphocyte function

artículo científico publicado en 1984

Effects of contiguous scars in dermatoscopic evaluation of clinically atypical melanocytic nevi

artículo científico publicado en 2012

Effects of dehydroepiandrosterone replacement on vascular function in primary and secondary adrenal insufficiency: a randomized crossover trial

artículo científico publicado en 2009

Effects of prostaglandin F(2α) on adipocyte biology relevant to graves' orbitopathy

artículo científico publicado en 2013

Evidence for thyrotropin receptor immunoreactivity in pretibial connective tissue from patients with thyroid-associated dermopathy

artículo científico publicado en 2002

Extrathyroidal thyroid hormone synthesis?

artículo científico publicado el 3 de mayo de 2011

Failure to demonstrate cell-mediated immune responses to thyroid antigens in Graves' disease using in vitro assays of lymphokine-mediated migration inhibition

artículo científico publicado en 1985

Future Research in Graves' Orbitopathy: From Priority Setting to Trial Design Through Patient and Public Involvement

artículo científico publicado en 2015

Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor

artículo científico publicado en 1998

Gsalpha signalling suppresses PPARgamma2 generation and inhibits 3T3L1 adipogenesis

artículo científico publicado en 2009

Gut Microbiome in BALB/c and C57BL/6J Mice Undergoing Experimental Thyroid Autoimmunity Associate with Differences in Immunological Responses and Thyroid Function

artículo científico publicado en 2018

Gut microbiota in experimental murine model of Graves' orbitopathy established in different environments may modulate clinical presentation of disease.

artículo científico publicado en 2018

Homology between thyroglobulin and acetylcholinesterase: an explanation for pathogenesis of Graves' ophthalmopathy?

artículo científico publicado en 1986

Identification of antigenic domains on the human sodium-iodide symporter which are recognized by autoantibodies from patients with autoimmune thyroid disease

artículo científico publicado en 2001

Identification of high molecular weight forms of inositol 1,4,5-trisphosphate 3-kinase in rat thymus and human lymphocytes

artículo científico publicado en 1994

Identification of the thyroid Na+/I- cotransporter as a potential autoantigen in thyroid autoimmune disease

artículo científico publicado en 1995

Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the recombinant TSH-R

scientific article published on 01 March 1994

Internet use and anxiety in people with melanoma and nonmelanoma skin cancer

artículo científico publicado en 2011

Longitudinal characterization of autoantibodies to the thyrotropin receptor (TRAb) during alemtuzumab therapy; evidence that TRAb may precede thyroid dysfunction by many years

artículo científico publicado en 2018

Mapping thyroid peroxidase epitopes using recombinant protein fragments

artículo científico publicado en 1995

Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin.

artículo científico publicado en 1993

Meeting abstracts from the 64th British Thyroid Association Annual Meeting: Newcastle, UK. 13/05/2016.

artículo científico publicado en 2017

Metabolic syndrome: is the preadipocyte to blame?

artículo científico publicado en 2012

Metamorphic thyroid autoimmunity

artículo científico publicado en 2008

Metformin reduces arterial stiffness and improves endothelial function in young women with polycystic ovary syndrome: a randomized, placebo-controlled, crossover trial

artículo científico publicado en 2009

Modulation of expression of somatostatin receptor subtypes in Graves' ophthalmopathy orbits: relevance to novel analogs.

artículo científico publicado en 2007

Molecular genetics of the thyrotropin receptor.

artículo científico publicado en 1992

Muscle autoantigens in thyroid associated ophthalmopathy: the limits of molecular genetics

artículo científico publicado en 1993

Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia

artículo científico publicado en 1998

New insights into the pathogenesis and nonsurgical management of Graves orbitopathy

artículo científico publicado en 2019

Novel TSHR germline mutation (Met463Val) masquerading as Graves' disease in a large Welsh kindred with hyperthyroidism

artículo científico publicado en 2000

Overexpression of the extracellular domain of the thyrotrophin receptor in bacteria; production of thyrotrophin-binding inhibiting immunoglobulins

scientific article published on 01 August 1994

Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor.

artículo científico publicado en 1996

Pediatric melanoma: an opportunity for psychosocial research

artículo científico publicado en 2010

Peroxisome proliferator-activated receptor-gamma in thyroid eye disease: contraindication for thiazolidinedione use?

artículo científico publicado en 2003

Possible targets for nonimmunosuppressive therapy of Graves' orbitopathy.

artículo científico publicado en 2014

Potent thyrotrophin receptor-blocking antibodies: a cause of transient congenital hypothyroidism and delayed thyroid development.

artículo científico publicado en 2004

Prevention and treatment of postpartum Graves' disease

artículo científico publicado el 1 de octubre de 1997

Production and application of polyclonal antibody to human thyroid transcription factor 2 reveals thyroid transcription factor 2 protein expression in adult thyroid and hair follicles and prepubertal testis

artículo científico publicado en 2003

Prostaglandin F2-Alpha Eye Drops (Bimatoprost) in Graves' Orbitopathy: A Randomized Controlled Double-Masked Crossover Trial (BIMA Trial)

scientific article published on 01 April 2019

Quantification of cells expressing the thyrotropin receptor in extraocular muscles in thyroid associated orbitopathy

artículo científico publicado en 2005

Re: "An activating mutation of the thyrotropin receptor gene in hereditary non-autoimmune hyperthyroidism" by Yung-Seng Lee et al. J Pediatr Endocrinol Metab 2002; 15: 211-215

artículo científico publicado en 2002

Recombinant TSH-receptor for determination of TSH-receptor-antibodies

artículo científico publicado en 1992

Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model

artículo científico publicado en 1994

Reevaluating thyrotropin receptor-induced mouse models of graves' disease and ophthalmopathy.

artículo científico publicado en 2004

Regulation and tissue distribution of the human sodium iodide symporter gene

scientific article published on 01 October 1998

Role of Hyaluronan in Human Adipogenesis: Evidence from in-Vitro and in-Vivo Studies

artículo científico publicado en 2019

Shining a light on thyroid eye disease

scientific article published on 28 February 2020

Stimulation of autologous blood lymphocytes by malignant lymphoma cells and homogenates

artículo científico publicado el 1 de diciembre de 1976

T-cell subset analysis of cryopreserved human peripheral blood mononuclear cells

scientific article published on 01 January 1983

TPOAb and Thyroid Function Are Not Associated with Breast Cancer Outcome: Evidence from a Large-Scale Study Using Data from the Taxotere as Adjuvant Chemotherapy Trial (TACT, CRUK01/001).

artículo científico publicado en 2017

TSH receptor activation and body composition

artículo científico publicado en 2009

The Modulation of the Human Sodium Iodide Symporter Activity by Graves’ Disease Sera1

artículo científico publicado el 1 de abril de 1998

The Molecular Genetics of Three Thyroid Autoantigens: Thyroglobulin, Thyroid Peroxidase and the Thyrotropin Receptor

artículo científico publicado el 1 de enero de 1990

The Role of Thyrotropin Receptor Activation in Adipogenesis and Modulation of Fat Phenotype

artículo científico publicado en 2017

The Search for Biomarkers of Disease: Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometry, Tears, and Thyroid-Associated Ophthalmopathy

artículo científico publicado el 1 de octubre de 2012

The W546X mutation of the thyrotropin receptor gene: potential major contributor to thyroid dysfunction in a Caucasian population

scientific article published on 01 March 2003

The microbiota and autoimmunity: Their role in thyroid autoimmune diseases.

artículo científico publicado en 2017

The prevalence and progression of autoimmune thyroid disease in the elderly

artículo científico publicado en 1984

The prevalence of anti-acetylcholinesterase antibodies in autoimmune disease

scientific article published on 01 December 2004

The second wave of the Controlled Antenatal Thyroid Screening (CATS II) study: the cognitive assessment protocol

artículo científico publicado en 2014

The sodium iodide symporter gene and its regulation by cytokines found in autoimmunity.

artículo científico publicado en 1998

The sodium iodide symporter is unlikely to be a thyroid/breast shared antigen.

artículo científico publicado en 2015

The thyrotropin receptor as a model to illustrate receptor and receptor antibody diseases

artículo científico publicado en 1995

The thyrotropin receptor in thyroid diseases.

artículo científico publicado en 1997

The thyrotropin receptor in thyroid eye disease.

artículo científico publicado en 1998

Thyroid stimulating immunoglobulins, like thyrotropin activate both the cyclic AMP and the PIP2 cascades in CHO cells expressing the TSH receptor.

artículo científico publicado en 1992

Thyroid transcription factor-2 gene expression in benign and malignant thyroid lesions.

artículo científico publicado en 2001

Thyroperoxidase, an auto-antigen with a mosaic structure made of nuclear and mitochondrial gene modules.

artículo científico publicado en 1987

Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector

artículo científico publicado en 1991

Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: contributory role in hyaluronan accumulation in thyroid dysfunction.

artículo científico publicado en 2009

Thyrotropin receptor transcripts in human adipose tissue

artículo científico publicado en 1997

Tissue specificity and serologic reactivity of an autoantigen associated with autoimmune thyroid disease

scientific article published on 01 August 1993

Towards an antigenic map of human thyroglobulin: identification of ten epitope-bearing sequences within the primary structure of thyroglobulin

artículo científico publicado en 1989

Transcription of thyroid autoantigens in non-expressing tissues.

artículo científico publicado en 1998

Transfer of thyroiditis, with syngeneic spleen cells sensitized with the human thyrotropin receptor, to naive BALB/c and NOD mice

artículo científico publicado en 1996

Transient congenital hypothyroidism due to thyroid-stimulating hormone receptor blocking antibodies: a case series

artículo científico publicado en 2011

Two novel mutations in the thyrotropin (TSH) receptor gene in a child with resistance to TSH.

artículo científico publicado en 1997

Unlike thyrotropin, thyroid-stimulating antibodies do not activate phospholipase C in human thyroid slices

artículo científico publicado en 1991

Unlocking the immunological mechanisms of orbital inflammation in thyroid eye disease

artículo científico publicado en 2002

W546X mutation of the thyrotropin receptor causes subclinical hypothyroidism in various clinical settings

artículo científico publicado en 2007

Western blot analysis of thyrotropin receptor expression in human thyroid tumours and correlation with TSH-binding

scientific article published on 01 November 1994

[Basedow disease following metastatic thyroid cancer]

artículo científico publicado en 1996