Lista de obras - Ahmed Ghallab - Dominio Público Uruguay

A systematic evaluation of the use of physiologically based pharmacokinetic modeling for cross-species extrapolation

artículo científico publicado en 2014

Activated ErbB3 Translocates to the Nucleus via Clathrin-independent Endocytosis, Which Is Associated with Proliferating Cells

artículo científico

Adverse outcome pathways: opportunities, limitations and open questions

artículo científico publicado en 2017

Bile micro-infarcts in cholestasis are initiated by rupture of the apical hepatocyte membrane and cause shunting of bile to sinusoidal blood

artículo científico publicado en 2018

Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity

scientific article published on 04 September 2018

Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins

artículo científico publicado en 2022

Contribution to the 3R Principle: Description of a Specimen-Specific Finite Element Model Simulating 3-Point-Bending Tests in Mouse Tibiae

artículo científico publicado en 2022

Fluoride: no evidence of developmental neurotoxicity due to current exposure levels in Europe

artículo científico publicado en 2020

Future perspectives of DILI prediction in vitro

artículo científico publicado en 2019

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue

artículo científico publicado en 2016

Hair histology as a tool for forensic identification of some domestic animal species

artículo científico publicado en 2018

Highlight Report: humanized mice reveal interspecies differences in triclosan hepatotoxicity

scientific article published on 21 November 2018

Highlight report: Blueprint for stem cell differentiation into liver cells.

artículo científico publicado en 2015

Highlight report: Necrosis-apoptosis conundrum of hepatocytes: mode of hepatocyte death after acetaminophen intoxication.

artículo científico publicado en 2018

Highlight report: New methods for quantification of bile canalicular dynamics.

artículo científico publicado en 2015

Highlight report: Role of the circadian clock system in breast cancer

artículo científico publicado en 2015

Highlight report: acetaminophen hepatotoxicity

artículo científico publicado en 2015

Highlight report: perspectives in stem cell research--unbiased quantification of the similarity between in vitro generated and primary hepatocytes

artículo científico publicado en 2015

Highlight report: the need of 'fit-for-purpose' controls for cell lines used in toxicity assays

scientific article published on 14 November 2018

Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity

artículo científico publicado en 2022

In vitro - in vivo correlation of gene expression alterations induced by liver carcinogens.

artículo científico publicado en 2012

In vitro systems: current limitations and future perspectives

artículo científico publicado en 2014

In vivo imaging of systemic transport and elimination of xenobiotics and endogenous molecules in mice.

artículo científico publicado en 2016

Influence of Liver Fibrosis on Lobular Zonation

scientific article published on 02 December 2019

Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A

artículo científico publicado en 2022

Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration

artículo científico publicado en 2014

Interspecies extrapolation by physiologically based pharmacokinetic modeling

artículo científico publicado en 2015

Intravital dynamic and correlative imaging reveals diffusion-dominated canalicular and flow-augmented ductular bile flux

scientific article published on 19 June 2020

Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases

artículo científico publicado en 2015

Modeling of early hepatocellular carcinoma

artículo científico publicado en 2018

Optimality in the zonation of ammonia detoxification in rodent liver.

artículo científico publicado en 2015

Perspectives in toxicologic pathology: quantification of bile canalicular networks

artículo científico publicado en 2014

Pharmacological inhibition of the ideal apical sodium-dependent bile acid transporter ASBT ameliorates cholestatic liver disease in mice

artículo científico publicado en 2019

Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage

artículo científico publicado en 2017

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

artículo científico publicado en 2019

Pyrrolizidine alkaloids act by toxicity to sinusoidal endothelial cells of the liver

scientific article published on 08 November 2019

Role of ductular reactive cells in recruiting immune cells

artículo científico publicado en 2020

Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSI

artículo científico publicado en 2018

Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney

artículo científico publicado en 2021

Systems Toxicology

artículo científico publicado en 2015

The ascending pathophysiology of cholestatic liver disease.

artículo científico publicado en 2016

The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity

artículo científico publicado en 2014

The virtual liver: state of the art and future perspectives

artículo científico publicado en 2014

Lista de obras de Ahmed Ghallab

A systematic evaluation of the use of physiologically based pharmacokinetic modeling for cross-species extrapolation

Activated ErbB3 Translocates to the Nucleus via Clathrin-independent Endocytosis, Which Is Associated with Proliferating Cells

Adverse outcome pathways: opportunities, limitations and open questions

Bile micro-infarcts in cholestasis are initiated by rupture of the apical hepatocyte membrane and cause shunting of bile to sinusoidal blood

Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity

Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins

Contribution to the 3R Principle: Description of a Specimen-Specific Finite Element Model Simulating 3-Point-Bending Tests in Mouse Tibiae

Fluoride: no evidence of developmental neurotoxicity due to current exposure levels in Europe

Future perspectives of DILI prediction in vitro

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue

Hair histology as a tool for forensic identification of some domestic animal species

Highlight Report: humanized mice reveal interspecies differences in triclosan hepatotoxicity

Highlight report: Blueprint for stem cell differentiation into liver cells.

Highlight report: Necrosis-apoptosis conundrum of hepatocytes: mode of hepatocyte death after acetaminophen intoxication.

Highlight report: New methods for quantification of bile canalicular dynamics.

Highlight report: Role of the circadian clock system in breast cancer

Highlight report: acetaminophen hepatotoxicity

Highlight report: perspectives in stem cell research--unbiased quantification of the similarity between in vitro generated and primary hepatocytes

Highlight report: the need of 'fit-for-purpose' controls for cell lines used in toxicity assays

Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity

In vitro - in vivo correlation of gene expression alterations induced by liver carcinogens.

In vitro systems: current limitations and future perspectives

In vivo imaging of systemic transport and elimination of xenobiotics and endogenous molecules in mice.

Influence of Liver Fibrosis on Lobular Zonation

Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A

Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration

Interspecies extrapolation by physiologically based pharmacokinetic modeling

Intravital dynamic and correlative imaging reveals diffusion-dominated canalicular and flow-augmented ductular bile flux

Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases

Modeling of early hepatocellular carcinoma

Optimality in the zonation of ammonia detoxification in rodent liver.

Perspectives in toxicologic pathology: quantification of bile canalicular networks

Pharmacological inhibition of the ideal apical sodium-dependent bile acid transporter ASBT ameliorates cholestatic liver disease in mice

Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

Pyrrolizidine alkaloids act by toxicity to sinusoidal endothelial cells of the liver

Role of ductular reactive cells in recruiting immune cells

Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSI

Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney

Systems Toxicology

The ascending pathophysiology of cholestatic liver disease.

The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity

The virtual liver: state of the art and future perspectives