Lista de obras - Marc Zapatka - Dominio Público Uruguay

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

artículo científico publicado en 2016

Analysis of Epstein-Barr Virus Genomes and Expression Profiles in Gastric Adenocarcinoma

artículo científico publicado en 2017

Association of mutation signature effectuating processes with mutation hotspots in driver genes and non-coding regions

artículo científico publicado en 2022

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

artículo científico publicado en 2016

Author Correction: The landscape of genomic alterations across childhood cancers

artículo científico publicado en 2018

BRCA1-associated breast and ovarian cancer risks in Poland: no association with commonly studied polymorphisms

artículo científico publicado en 2009

Basement membrane component laminin-5 is a target of the tumor suppressor Smad4.

artículo científico publicado en 2006

Breast cancer: a candidate gene approach across the estrogen metabolic pathway

artículo científico publicado en 2007

Bronchoalveolar lavage fluid of lung cancer patients: Mapping the uncharted waters using proteomics technology

CCM2 mediates death signaling by the TrkA receptor tyrosine kinase

artículo científico publicado en 2009

Chromosome 17/17q gain and unaltered profiles in high resolution array-CGH are prognostically informative in neuroblastoma.

artículo científico publicado en 2014

Chromothripsis in human breast cancer

scientific article published on 24 September 2020

Comparative parallel multi-omics analysis during the induction of pluripotent and trophectoderm states

artículo científico publicado en 2022

Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation

scientific article published on 27 December 2018

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

artículo científico publicado en 2012

Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies

artículo científico publicado en 2013

DNA methylation-based classification of central nervous system tumours.

artículo científico publicado en 2018

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

artículo científico publicado en 2014

Differential clinical significance of individual NKG2D ligands in melanoma: soluble ULBP2 as an indicator of poor prognosis superior to S100B.

artículo científico publicado en 2009

Differential proteome analysis of conditioned media to detect Smad4 regulated secreted biomarkers in colon cancer

artículo científico publicado en 2005

Dissecting the genomic complexity underlying medulloblastoma

artículo científico publicado en 2012

Divergent mechanisms underlie Smad4-mediated positive regulation of the three genes encoding the basement membrane component laminin-332 (laminin-5).

artículo científico publicado en 2008

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

artículo científico publicado en 2012

EPIG-04THE CHROMATIN LANDSCAPE OF MEDULLOBLASTOMA.

artículo científico publicado en 2015

ERCC5 p.Asp1104His and ERCC2 p.Lys751Gln Polymorphisms Are Independent Prognostic Factors for the Clinical Course of Melanoma

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

artículo científico publicado en 2014

GENE-06. DISTINCT MOLECULAR SUBGROUPS OF TUMORS OF THE PINEAL REGION CORRELATE WITH CLINICAL PARAMETERS AND GENETIC ALTERATIONS

artículo científico publicado en 2019

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

artículo científico publicado en 2014

Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

artículo científico publicado en 2012

Genome-wide identification of translationally inhibited and degraded miR-155 targets using RNA-interacting protein-IP.

artículo científico publicado en 2013

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

artículo científico publicado en 2019

Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis

artículo científico publicado en 2017

High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition

artículo científico publicado en 2007

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

artículo científico publicado en 2012

Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration

scientific article published on 07 November 2019

Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy

artículo científico publicado en 2007

Integrative genomic and transcriptomic analysis of leiomyosarcoma.

artículo científico publicado en 2018

Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks

artículo científico publicado en 2019

Loss of Smad4 correlates with loss of the invasion suppressor E-cadherin in advanced colorectal carcinomas

artículo científico publicado en 2004

Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis.

artículo científico publicado en 2013

Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma

scientific article published in Nature Communications

MED12 mutations and NOTCH signalling in chronic lymphocytic leukaemia.

artículo científico publicado en 2017

Merkel cell polyomavirus status is not associated with clinical course of Merkel cell carcinoma.

artículo científico publicado en 2011

MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival

artículo científico publicado en 2011

Microphthalmia-associated transcription factor gene amplification in metastatic melanoma is a prognostic marker for patient survival, but not a predictive marker for chemosensitivity and chemotherapy response

artículo científico publicado en 2007

Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations

scientific article published on 25 November 2019

Monitoring CSF proteome alterations in amyotrophic lateral sclerosis: obstacles and perspectives in translating a novel marker panel to the clinic

artículo científico publicado en 2012

Oligonucleotide array-based comparative genomic hybridization (aCGH) of 90 neuroblastomas reveals aberration patterns closely associated with relapse pattern and outcome

scientific article published on 01 December 2006

Ontological Analysis and Pathway Modelling in Drug Discovery

PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING.

artículo científico publicado en 2016

Pilocytic Astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response

artículo científico publicado en 2020

Postoperative serum proteomic profiles may predict recurrence-free survival in high-risk primary breast cancer

artículo científico publicado en 2011

Proteomic analysis of field cancerization in pharynx and oesophagus: a prospective pilot study.

artículo científico publicado en 2010

Proteomic bronchiolitis obliterans syndrome risk monitoring in lung transplant recipients

artículo científico publicado en 2011

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival.

artículo científico publicado en 2011

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

artículo científico publicado en 2013

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

artículo científico publicado en 2013

Relevance of PTEN loss in brain metastasis formation in breast cancer patients

artículo científico publicado en 2012

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays

artículo científico publicado en 2013

Serum amyloid A as a prognostic marker in melanoma identified by proteomic profiling

artículo científico publicado en 2009

Serum proteomics and disease-specific biomarkers of patients with advanced gastric cancer

artículo científico publicado en 2010

Smad4 deficiency in cervical carcinoma cells.

artículo científico publicado en 2005

Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma

artículo científico publicado en 2012

TB-17A COMPREHENSIVE PAN-CANCER ANALYSIS OF CHILDHOOD MALIGNANCIES.

artículo científico publicado en 2016

Telomere dysfunction and chromothripsis

artículo científico publicado en 2016

The FRA2C common fragile site maps to the borders of MYCN amplicons in neuroblastoma and is associated with gross chromosomal rearrangements in different cancers.

artículo científico publicado en 2011

The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer

artículo científico publicado en 2017

The landscape of chromothripsis across adult cancer types

artículo científico publicado en 2020

The landscape of genomic alterations across childhood cancers

artículo científico publicado en 2018

The landscape of viral associations in human cancers

artículo científico publicado en 2020

The whole-genome landscape of medulloblastoma subtypes

artículo científico publicado en 2017

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

artículo científico publicado en 2017

Tumor suppressor Smad4 mediates downregulation of the anti-adhesive invasion-promoting matricellular protein SPARC: Landscaping activity of Smad4 as revealed by a "secretome" analysis.

artículo científico publicado en 2004

Tumor-derived exosomes modulate PD-L1 expression in monocytes.

artículo científico publicado en 2017

Tumor-microenvironment interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma

artículo científico publicado en 2012

Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli

artículo científico publicado en 2007

confFuse: High-Confidence Fusion Gene Detection across Tumor Entities.

artículo científico publicado en 2017

qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AXL.

artículo científico publicado en 2010

Lista de obras de Marc Zapatka

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

Analysis of Epstein-Barr Virus Genomes and Expression Profiles in Gastric Adenocarcinoma

Association of mutation signature effectuating processes with mutation hotspots in driver genes and non-coding regions

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

Author Correction: The landscape of genomic alterations across childhood cancers

BRCA1-associated breast and ovarian cancer risks in Poland: no association with commonly studied polymorphisms

Basement membrane component laminin-5 is a target of the tumor suppressor Smad4.

Breast cancer: a candidate gene approach across the estrogen metabolic pathway

Bronchoalveolar lavage fluid of lung cancer patients: Mapping the uncharted waters using proteomics technology

CCM2 mediates death signaling by the TrkA receptor tyrosine kinase

Chromosome 17/17q gain and unaltered profiles in high resolution array-CGH are prognostically informative in neuroblastoma.

Chromothripsis in human breast cancer

Comparative parallel multi-omics analysis during the induction of pluripotent and trophectoderm states

Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies

DNA methylation-based classification of central nervous system tumours.

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

Differential clinical significance of individual NKG2D ligands in melanoma: soluble ULBP2 as an indicator of poor prognosis superior to S100B.

Differential proteome analysis of conditioned media to detect Smad4 regulated secreted biomarkers in colon cancer

Dissecting the genomic complexity underlying medulloblastoma

Divergent mechanisms underlie Smad4-mediated positive regulation of the three genes encoding the basement membrane component laminin-332 (laminin-5).

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

EPIG-04THE CHROMATIN LANDSCAPE OF MEDULLOBLASTOMA.

ERCC5 p.Asp1104His and ERCC2 p.Lys751Gln Polymorphisms Are Independent Prognostic Factors for the Clinical Course of Melanoma

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

GENE-06. DISTINCT MOLECULAR SUBGROUPS OF TUMORS OF THE PINEAL REGION CORRELATE WITH CLINICAL PARAMETERS AND GENETIC ALTERATIONS

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

Genome-wide identification of translationally inhibited and degraded miR-155 targets using RNA-interacting protein-IP.

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis

High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration

Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy

Integrative genomic and transcriptomic analysis of leiomyosarcoma.

Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks

Loss of Smad4 correlates with loss of the invasion suppressor E-cadherin in advanced colorectal carcinomas

Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis.

Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma

MED12 mutations and NOTCH signalling in chronic lymphocytic leukaemia.

Merkel cell polyomavirus status is not associated with clinical course of Merkel cell carcinoma.

MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival

Microphthalmia-associated transcription factor gene amplification in metastatic melanoma is a prognostic marker for patient survival, but not a predictive marker for chemosensitivity and chemotherapy response

Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations

Monitoring CSF proteome alterations in amyotrophic lateral sclerosis: obstacles and perspectives in translating a novel marker panel to the clinic

Oligonucleotide array-based comparative genomic hybridization (aCGH) of 90 neuroblastomas reveals aberration patterns closely associated with relapse pattern and outcome

Ontological Analysis and Pathway Modelling in Drug Discovery

PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING.

Pilocytic Astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response

Postoperative serum proteomic profiles may predict recurrence-free survival in high-risk primary breast cancer

Proteomic analysis of field cancerization in pharynx and oesophagus: a prospective pilot study.

Proteomic bronchiolitis obliterans syndrome risk monitoring in lung transplant recipients

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival.

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

Relevance of PTEN loss in brain metastasis formation in breast cancer patients

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays

Serum amyloid A as a prognostic marker in melanoma identified by proteomic profiling

Serum proteomics and disease-specific biomarkers of patients with advanced gastric cancer

Smad4 deficiency in cervical carcinoma cells.

Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma

TB-17A COMPREHENSIVE PAN-CANCER ANALYSIS OF CHILDHOOD MALIGNANCIES.

Telomere dysfunction and chromothripsis

The FRA2C common fragile site maps to the borders of MYCN amplicons in neuroblastoma and is associated with gross chromosomal rearrangements in different cancers.

The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer

The landscape of chromothripsis across adult cancer types

The landscape of genomic alterations across childhood cancers

The landscape of viral associations in human cancers

The whole-genome landscape of medulloblastoma subtypes

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

Tumor suppressor Smad4 mediates downregulation of the anti-adhesive invasion-promoting matricellular protein SPARC: Landscaping activity of Smad4 as revealed by a "secretome" analysis.

Tumor-derived exosomes modulate PD-L1 expression in monocytes.

Tumor-microenvironment interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma

Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli

confFuse: High-Confidence Fusion Gene Detection across Tumor Entities.

qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AXL.