Lista de obras - Daniel Fazakerley - Dominio Público Uruguay

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

scientific article published on 10 February 2009

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

artículo científico publicado en 2009

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

artículo científico publicado en 2014

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

artículo científico publicado en 2017

Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes.

artículo científico publicado en 2011

An improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction.

artículo científico publicado en 2017

Circulating AFABP promotes insulin secretion

artículo científico publicado en 2015

Direction pathway analysis of large-scale proteomics data reveals novel features of the insulin action pathway

artículo científico publicado en 2013

Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin

scientific article published on 21 January 2020

Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2.

artículo científico publicado en 2013

Exposure to solar ultraviolet radiation limits diet-induced weight gain, increases liver triglycerides and prevents the early signs of cardiovascular disease in mice

scientific article published on 28 February 2019

GLUT4 exocytosis.

artículo científico publicado en 2011

Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates.

artículo científico publicado en 2015

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

scientific article published on 02 December 2019

Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

artículo científico publicado en 2014

Insulin regulates Rab3-Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes

artículo científico publicado en 2015

Insulin signalling requires glucose to promote lipid anabolism in adipocytes

artículo científico publicado en 2020

Integrating adipocyte insulin signaling and metabolism in the multi-omics era

artículo científico publicado en 2022

Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes

artículo científico publicado en 2009

Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway

artículo científico publicado en 2015

Lactate production is a prioritized feature of adipocyte metabolism

artículo científico publicado en 2019

Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: a comprehensive resource for in vitro studies of hepatic metabolism

artículo científico publicado en 2019

Mapping insulin/GLUT4 circuitry.

scientific article published on 15 March 2011

Membrane Topology of Trafficking Regulator of GLUT4 1 (TRARG1)

artículo científico publicado en 2018

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.

artículo científico publicado en 2018

Mitochondrial oxidants, but not respiration, are sensitive to glucose in adipocytes

artículo científico publicado en 2019

Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation.

artículo científico publicado en 2018

Muscle and adipose tissue insulin resistance: malady without mechanism?

artículo científico publicado en 2018

Muscling in on GLUT4 kinetics.

artículo científico publicado en 2010

Novel systems for dynamically assessing insulin action in live cells reveals heterogeneity in the insulin response.

artículo científico publicado en 2013

Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle

artículo científico publicado en 2013

Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes

artículo científico publicado en 2015

Re-fraction: a machine learning approach for deterministic identification of protein homologues and splice variants in large-scale MS-based proteomics

artículo científico publicado en 2012

Selective insulin resistance in adipocytes

artículo científico publicado en 2015

Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes

scientific article published on 22 September 2019

Systemic VEGF-A Neutralization Ameliorates Diet-Induced Metabolic Dysfunction

artículo científico publicado en 2014

Terminal Galactosylation and Sialylation Switching on Membrane Glycoproteins upon TNF-Alpha-Induced Insulin Resistance in Adipocytes

artículo científico publicado en 2015

The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle.

artículo científico publicado en 2015

The amino acid transporter, SLC1A3, is plasma membrane-localised in adipocytes and its activity is insensitive to insulin

artículo científico publicado en 2016

The role of the Niemann-Pick disease, type C1 protein in adipocyte insulin action.

artículo científico publicado en 2014

The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes

artículo científico publicado en 2018

Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

artículo científico publicado en 2016

mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes.

artículo científico publicado en 2016

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

artículo científico publicado en 2016

Lista de obras de Daniel Fazakerley

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes.

An improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction.

Circulating AFABP promotes insulin secretion

Direction pathway analysis of large-scale proteomics data reveals novel features of the insulin action pathway

Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin

Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2.

Exposure to solar ultraviolet radiation limits diet-induced weight gain, increases liver triglycerides and prevents the early signs of cardiovascular disease in mice

GLUT4 exocytosis.

Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates.

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

Insulin regulates Rab3-Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes

Insulin signalling requires glucose to promote lipid anabolism in adipocytes

Integrating adipocyte insulin signaling and metabolism in the multi-omics era

Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes

Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway

Lactate production is a prioritized feature of adipocyte metabolism

Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: a comprehensive resource for in vitro studies of hepatic metabolism

Mapping insulin/GLUT4 circuitry.

Membrane Topology of Trafficking Regulator of GLUT4 1 (TRARG1)

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.

Mitochondrial oxidants, but not respiration, are sensitive to glucose in adipocytes

Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation.

Muscle and adipose tissue insulin resistance: malady without mechanism?

Muscling in on GLUT4 kinetics.

Novel systems for dynamically assessing insulin action in live cells reveals heterogeneity in the insulin response.

Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle

Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes

Re-fraction: a machine learning approach for deterministic identification of protein homologues and splice variants in large-scale MS-based proteomics

Selective insulin resistance in adipocytes

Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes

Systemic VEGF-A Neutralization Ameliorates Diet-Induced Metabolic Dysfunction

Terminal Galactosylation and Sialylation Switching on Membrane Glycoproteins upon TNF-Alpha-Induced Insulin Resistance in Adipocytes

The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle.

The amino acid transporter, SLC1A3, is plasma membrane-localised in adipocytes and its activity is insensitive to insulin

The role of the Niemann-Pick disease, type C1 protein in adipocyte insulin action.

The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes

Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes.

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3