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Lista de obras de Thierry Soussi

A functional analysis of p53 during early development of Xenopus laevis.

artículo científico publicado en 1997

A monoclonal antibody against DNA binding helix of p53 protein

artículo científico publicado en 2001

A new set of monoclonal antibodies directed to proline-rich and central regions of p53.

artículo científico publicado en 2004

APC gene: database of germline and somatic mutations in human tumors and cell lines

artículo científico publicado en 1998

Absence of p53 germ-line mutations in bilateral breast cancer patients

artículo científico publicado en 1992

Advances in carcinogenesis: A historical perspective from observational studies to tumor genome sequencing and TP53 mutation spectrum analysis ⬇️

artículo científico publicado el 23 de julio de 2011

Analysis of TP53 mutation status in human cancer cell lines: a reassessment

artículo científico publicado en 2014

Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: distribution on primary structure and exposure on protein surface

article

Analysis of p53 antibody response in patients with squamous cell carcinoma of the head and neck

artículo científico publicado en 1996

Analysis of p53 serum antibodies in patients with head and neck squamous cell carcinoma

artículo científico publicado en 1996

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

artículo científico publicado en 1994

Anti-apoptotic activity of p53 maps to the COOH-terminal domain and is retained in a highly oncogenic natural mutant

artículo científico publicado en 1999

Anti-p53 antibodies are rarely detected in serum of patients with rheumatoid arthritis and Sjögren's syndrome

artículo científico publicado en 1999

Antibodies against p53 protein in serum of patients with benign or malignant pancreatic and biliary diseases.

artículo científico publicado en 1995

Author Correction: Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux

artículo científico publicado en 2019

Breast-cancer stromal cells with TP53 mutations

artículo científico publicado en 2008

Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene?

artículo científico publicado en 1994

Cancer and the heat shock response.

artículo científico publicado en 1994

Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73

scientific article published in Journal of Biological Chemistry

Critical residues of epitopes recognized by several anti-p53 monoclonal antibodies correspond to key residues of p53 involved in interactions with the mdm2 protein

artículo científico publicado en 2000

DNA-binding properties of the major structural protein of simian virus 40

artículo científico publicado en 1986

Data mining the p53 pathway in the Fugu genome: evidence for strong conservation of the apoptotic pathway

artículo científico publicado en 2003

Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

artículo científico publicado en 2012

Database and software for the analysis of mutations at the human p53 gene.

artículo científico publicado en 1994

Databases and software for the analysis of mutations in the human p53 gene, human hprt gene and both the lacI and lacZ gene in transgenic rodents ⬇️

artículo científico publicado el 1 de enero de 1998

Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and both the lacI and lacZ gene in transgenic rodents.

artículo científico publicado en 1997

Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and the lacZ gene in transgenic rodents.

artículo científico publicado en 1996

Detection and sequencing of p53 gene mutations in bronchial biopsy samples in patients with lung cancer

artículo científico publicado en 1994

Detection of p73 antibodies in patients with various types of cancer: immunological characterization

artículo científico publicado en 2001

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation

artículo científico publicado en 2018

Effects of electrical brainstem stimulation on tinnitus.

artículo científico publicado en 1994

Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog

artículo científico publicado en 2022

Expression of p53 in oral squamous cell carcinoma is associated with the presence of IgG and IgA p53 autoantibodies in sera and saliva of the patients

scientific article published on 01 September 2000

Fiche n 33 : BCR

scientific article published on 01 March 2000

Focus on the p53 gene and cancer: advances in TP53 mutation research

scientific article published on 01 March 2003

Foreign bodies in the respiratory tract. Diagnosis and treatment

artículo científico publicado en 1996

Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study.

artículo científico publicado en 2006

Genetic alterations in localized prostate cancer: Identification of a common region of deletion on chromosome arm 18q

artículo científico publicado en 1994

Genetic profiling of CLL: a 'TP53 addict' perspective.

artículo científico publicado en 2016

Germline mutations of the p53 tumor-suppressor gene in cancer-prone families: a review

scientific article published on 01 February 1993

Harmonized microarray/mutation scanning analysis of TP53 mutations in undissected colorectal tumors.

artículo científico publicado en 2004

High prevalence of cancer-associated TP53 variants in the gnomAD database: A word of caution concerning the use of variant filtering

scientific article published on 28 March 2019

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

artículo científico publicado en 2020

Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network

scientific article published on 26 November 2019

Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

artículo científico publicado en 2019

Is p53 a protein that predicts the response to chemotherapy in node negative breast cancer?

scientific article published on 01 January 1998

Lack of HIN-1 methylation defines specific breast tumor subtypes including medullary carcinoma of the breast and BRCA1-linked tumors

artículo científico publicado en 2003

Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate

artículo científico publicado en 2019

Linear antigenic sites defined by the B-cell response to human p53 are localized predominantly in the amino and carboxy-termini of the protein

scientific article published on 01 July 1994

Locus-specific databases in cancer: what future in a post-genomic era? The TP53 LSDB paradigm

artículo científico

Locus-specific mutation databases: pitfalls and good practice based on the p53 experience

scientific article published on 01 January 2006

Lymphomas in patients with Sjogren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses

scientific article published on 01 July 1997

MUT-TP53 2.0: a novel versatile matrix for statistical analysis of TP53 mutations in human cancer

artículo científico publicado en 2010

MUT-TP53: a versatile matrix for TP53 mutation verification and publication

scientific article published on 01 November 2006

Medullary breast carcinoma: prognostic implications of p53 expression

scientific article published on 01 April 2003

Meta-analysis of the p53 Mutation Database for Mutant p53 Biological Activity Reveals a Methodologic Bias in Mutation Detection

article

Molecular genetic analysis of p53 intratumoral heterogeneity in human astrocytic brain tumors.

artículo científico publicado en 2007

Monitoring of p53 autoantibodies in lung cancer during therapy: relationship to response to treatment.

artículo científico publicado en 1998

Monoclonal antibodies raised against Xenopus p53 interact with human p73

scientific article published in February 2002

Mutant p53 protein localized in the cytoplasm inhibits autophagy

artículo científico publicado en 2008

Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

artículo científico publicado en 1999

Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma

artículo científico publicado en 2010

Mutations in p53 produce a common conformational effect that can be detected with a panel of monoclonal antibodies directed toward the central part of the p53 protein

artículo científico publicado en 1994

Nucleotide sequence of a cDNA encoding the rat p53 nuclear oncoprotein.

artículo científico publicado en 1988

P53 gene alterations in human tumors: perspectives for cancer control.

artículo científico publicado en 1997

Primary proliferative T cell response to wild-type p53 protein in patients with breast cancer

artículo científico publicado en 1995

Production of human p53 specific monoclonal antibodies and their use in immunohistochemical studies of tumor cells

scientific article published on 01 February 1993

Prognostic significance of circulating P53 antibodies in patients undergoing surgery for locoregional breast cancer.

artículo científico publicado en 1995

Prognostic significance of serum p53 antibodies in patients with limited-stage small cell lung cancer.

artículo científico publicado en 2000

Quantitative fish determination of chromosome 3 arm imbalances in lung tumors by automated image cytometry

scientific article published on 26 October 2004

Rainbow trout p53: cDNA cloning and biochemical characterization

artículo científico publicado en 1992

Rapid and sensitive p53 alteration analysis in biopsies from lung cancer patients using a functional assay and a universal oligonucleotide array: a prospective study

artículo científico publicado en 2004

Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations

artículo científico publicado en 2005

Recommendations for analyzing and reporting TP53 gene variants in the high-throughput sequencing era.

artículo científico

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

artículo científico publicado en 2017

Regulation of mutant p53 temperature-sensitive DNA binding.

artículo científico publicado en 1996

Regulation of the specific DNA binding activity of Xenopus laevis p53: evidence for conserved regulation through the carboxy-terminus of the protein.

artículo científico publicado en 1998

Serum p53 antibodies as early markers of lung cancer

scientific article published on 01 July 1995

Serum p53 antibodies in correlation to other biological parameters of breast cancer

scientific article published on 01 January 2003

Serum p53 antibodies in patients with lung cancer: correlation with clinicopathologic features and smoking

scientific article published on 01 March 2003

Serum p53 antibodies in small cell lung cancer: the lack of prognostic relevance

scientific article published on 01 January 2001

Serum p53 antibody assay: evaluation in colorectal cancer

artículo científico publicado en 2000

Seshat: A Web service for accurate annotation, validation, and analysis of TP53 variants generated by conventional and next-generation sequencing

artículo científico publicado en 2018

Shaping genetic alterations in human cancer: the p53 mutation paradigm

artículo científico publicado en 2007

Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides

artículo científico publicado en 2003

Single-molecule DNA sequencing of acute myeloid leukemia and myelodysplastic syndromes with multiple TP53 alterations.

artículo científico publicado en 2017

Splice mutations in the p53 gene: case report and review of the literature.

artículo científico publicado en 2003

Squamous cell carcinomas after allogeneic bone marrow transplantation for aplastic anemia: further evidence of a multistep process

artículo científico publicado en 1998

Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux

artículo científico publicado en 2019

Stabilization and expression of high levels of p53 during early development in Xenopus laevis.

artículo científico publicado en 1993

Stimulation of rat liver alpha- and beta-type DNA polymerases by an homologous DNA-unwinding protein

scientific article published on 01 July 1977

Structural aspects of the p53 protein in relation to gene evolution: a second look.

artículo científico publicado en 1996

Synonymous Somatic Variants in Human Cancer Are Not Infamous: A Plea for Full Disclosure in Databases and Publications.

artículo científico publicado en 2016

TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade

artículo científico publicado el 1 de enero de 2011

TP53 and 53BP1 Reunited

artículo científico publicado en 2016

TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations

artículo científico publicado en 2010

TP53 mutations are early events in chronic lymphocytic leukemia disease progression and precede evolution to complex karyotypes

artículo científico publicado en 2016

TP53 mutations in human cancer: database reassessment and prospects for the next decade

artículo científico

TP53 tumor suppressor gene: a model for investigating human mutagenesis

artículo científico publicado el 1 de enero de 1992

TP53: an oncogene in disguise.

artículo científico

Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice

artículo científico publicado en 2002

The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment

artículo científico publicado en 2005

The TP53 gene network in a postgenomic era.

artículo científico

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis.

artículo científico publicado en 2012

The UMD TP53 database and website: update and revisions

scientific article published on 01 January 2006

The UMD-p53 database: new mutations and analysis tools

artículo científico publicado en 2003

The cDNA cloning and immunological characterization of hamster p53.

artículo científico publicado en 1992

The history of p53. A perfect example of the drawbacks of scientific paradigms

artículo científico publicado en 2010

The human BTG2/TIS21/PC3 gene: genomic structure, transcriptional regulation and evaluation as a candidate tumor suppressor gene

artículo científico publicado en 2002

The humoral response to the tumor-suppressor gene-product p53 in human cancer: implications for diagnosis and therapy

scientific article published on 01 August 1996

The p53 pathway and human cancer

artículo científico publicado en 2005

The p53 tumor suppressor gene: from molecular biology to clinical investigation.

artículo científico publicado en 2000

The role of p53 in normal cells and in cancer development

artículo científico publicado en 1997

ThinPrep-processed fine-needle samples of breast are effective material for RNA- and DNA-based molecular diagnosis: application to p53 mutation analysis.

artículo científico publicado en 2003

UMD (Universal Mutation Database): 2005 update

artículo científico publicado en 2005

Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan

scientific article published on 01 July 2019

Versatile analysis of multiple macromolecular interactions by SPR imaging: application to p53 and DNA interaction

artículo científico publicado en 2004

Very low incidence of p53 antibodies in adult non-Hodgkin's lymphoma and multiple myeloma

artículo científico publicado en 1998

When mutant p53 plays hide and seek: a new challenge for diagnosis and therapy?

artículo científico publicado en 2008

Xenopus laevis p53 protein: sequence-specific DNA binding, transcriptional regulation and oligomerization are evolutionarily conserved.

artículo científico publicado en 1995

[44 .PMS2 (post meiotic segregation increased, S. cerevisiae 2]

scientific article published on 01 April 2001

[BLM (RCQL2) or Bloom Syndrome]

artículo científico publicado en 2001

[Bcl2-associated X protein]

artículo científico publicado en 2001

[Card no. 32: ATM (Ataxia Telangiectasia Mutated)]

artículo científico publicado en 2000

[Case No. 36: E-cadherin (uvomorulin or CDH1]

scientific article published on 01 September 2000

[Case No. 37: hdm2 (mdm2 in mice)]

scientific article published on 01 September 2000

[Chart 48: FANCG/XRCC9 (type G Fanconi's anemia)]

scientific article published on 01 December 2001

[Chart no 45 - WRN (RCQL3)]

scientific article published on 01 June 2001

[Chart no. 30: FANCA (Fanconi's anemia type A). Repair gene?]

artículo científico publicado en 1999

[File no. 40. DNA polymerase n (Pol H) in hRad30A. Repair gene]

artículo científico publicado en 2000

[File no. 41. VHL (von Hippel-Lindau). Tumor suppressor gene]

scientific article published on 01 November 2000

[File no.47: CMYC]

scientific article published on 01 November 2001

[Genes & cancer. Card no. 28: PTEN (MMAC, TEP-1) (phosphatase and tensin homolog deleted on chromosome 10)]

artículo científico publicado en 1999

[Genes and cancer. NBS1 (Nijmegen breakage syndrome). Repair gene]

artículo científico publicado en 1999

[Genetics and cancer: fundamental and clinical aspects]

artículo científico publicado en 2001

[Ha-ras, N-ras et Ki-ras]

scientific article published on 01 February 2001

[INK4a-ARF (MTS1) or inhibitor of CDK-alternating reading frame (multiple tumor suppressor gene)]

scientific article published on 01 July 1999

[Immunochemistry and genotype analysis of tumors. Second part: What future for the molecular diagnosis of tumors?]

scientific article published on 01 April 2002

[Li-Fraumeni syndrome and germ-line mutations of the p53 gene]

artículo científico publicado en 1994

[P53 antibodies: a new method for the analysis of alterations of the p53 gene: application to breast cancer]

scientific article published on 01 April 1996

[P53 tumor suppressor gene]

scientific article published on 01 February 1993

[PML (promyelocytic leukemia). Oncogene]

artículo científico publicado en 1999

[PTPC (Patched). Tumor suppressor gene]

artículo científico publicado en 1999

[Perspectives of practical application for studies of gene p53]

artículo científico publicado en 1994

[Record no. 22: Beta-catenin]

artículo científico publicado en 1999

[Record no. 23: hMLH1]

scientific article published on 01 March 1999

[Record no. 34: hSNF5/INI1 (SMARCB1)]

scientific article published on 01 April 2000

[Record no. 38: TGFBR2 (type II TGFbeta receptor)]

artículo científico publicado en 2000

[Record no. 39: p53 (TP53)]

scientific article published on 01 October 2000

[Role of the p53 gene in human malignant tumors. A major discovery in oncology]

scientific article published on 01 December 1993

[The p53 gene and protein in bronchial carcinogenesis:from biological to clinical aspects]

artículo científico publicado en 1994

[Tumor suppressor p53 gene: a potential target for cancer therapy?]

artículo científico publicado en 1997

[p53 and Rb, clinical and therapeutic perspectives]

scientific article published on 01 January 1993

[p53 mutations and resistance to chemotherapy: a stab in the back for p73?].

artículo científico publicado en 2003

p53 Website and analysis of p53 gene mutations in human cancer: Forging a link between epidemiology and carcinogenesis

article

p53 alterations in human cancer: more questions than answers.

artículo científico publicado en 2007

p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series.

artículo científico publicado en 2000

p53 antibodies in the saliva of patients with squamous cell carcinoma of the oral cavity

artículo científico publicado en 1998

p53 antibodies in the sera of lung cancer patients: comparison with p53 mutation in the tumour tissue

scientific article published on 01 June 1995

p53 gene alterations in human hematological malignancies: a review

artículo científico publicado en 1991

p53 gene mutation: software and database

artículo científico publicado en 1998

p53 gene mutation: software and database.

artículo científico publicado en 1996

p53 immunolabeling in archival paraffin-embedded tissues: optimal protocol based on microwave heating for eight antibodies on lung carcinomas.

artículo científico

p53 mutation as a genetic trait of typical medullary breast carcinoma

artículo científico publicado en 1999

p53 mutations and resistance to chemotherapy: A stab in the back for p73 ⬇️

artículo científico publicado el 1 de abril de 2003

p53 mutations in BRCA1-associated familial breast cancer

artículo científico publicado en 1998

p53-dependent pathway of radio-induced apoptosis is altered in Fanconi anemia

artículo científico publicado en 1995

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