Lista de obras - Graça Porto - Dominio Público Uruguay

A Portuguese patient homozygous for the -25G>A mutation of the HAMP promoter shows evidence of steady-state transcription but fails to up-regulate hepcidin levels by iron

artículo científico publicado en 2005

A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts a less severe expression of hereditary hemochromatosis.

artículo científico publicado en 2008

A novel mutation in the CUB sequence of matriptase-2 (TMPRSS6) is implicated in iron-resistant iron deficiency anaemia -- response to Jaspers et al.

artículo científico publicado en 2012

A putative gene located at the MHC class I region around the D6S105 marker contributes to the setting of CD8+ T-lymphocyte numbers in humans.

artículo científico publicado en 2007

Accurate simultaneous quantification of liver steatosis and iron overload in diffuse liver diseases with MRI.

artículo científico publicado en 2017

Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils

artículo científico publicado en 2013

CAT53 and HFE alleles in Alzheimer's disease: a putative protective role of the C282Y HFE mutation

artículo científico publicado en 2009

Calreticulin Is Expressed on the Cell Surface of Activated Human Peripheral Blood T Lymphocytes in Association with Major Histocompatibility Complex Class I Molecules

artículo científico publicado en 1999

Co-selection of the H63D mutation and the HLA-A29 allele: a new paradigm of linkage disequilibrium?

artículo científico publicado en 2002

Comparative study between Hfe-/- and beta2m-/- mice: progression with age of iron status and liver pathology

scientific article published on 01 August 2006

Correction: Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis

artículo científico publicado en 2019

Decreased CD8-p561ck Activity in Peripheral Blood T-Lymphocytes from Patients with Hereditary Haemochromatosis

artículo científico publicado en 1994

EMQN best practice guidelines for the molecular genetic diagnosis of hereditary hemochromatosis (HH).

artículo científico publicado en 2015

Effects of highly conserved major histocompatibility complex (MHC) extended haplotypes on iron and low CD8+ T lymphocyte phenotypes in HFE C282Y homozygous hemochromatosis patients from three geographically distant areas

artículo científico publicado en 2013

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha

artículo científico publicado en 2008

Expression of iron-related proteins in feline and canine mammary gland reveals unexpected accumulation of iron

artículo científico publicado en 2017

Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation

artículo científico publicado en 2013

Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis

artículo científico publicado en 2016

HFE Related Hemochromatosis: Uncovering the Inextricable Link between Iron Homeostasis and the Immunological System

scientific article published on 22 August 2019

HFE Variants and the Expression of Iron-Related Proteins in Breast Cancer-Associated Lymphocytes and Macrophages

scientific article published on 27 December 2016

HFE mutations in the pathobiology of hemophilic arthropathy

artículo científico publicado en 2005

Hemochromatosis and pregnancy: iron stores in the Hfe-/- mouse are not reduced by multiple pregnancies.

artículo científico publicado en 2010

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

artículo científico publicado en 2017

Hepcidin messenger RNA expression in human lymphocytes

artículo científico publicado en 2010

Impact of a dengue outbreak experience in the preventive perceptions of the community from a temperate region: Madeira Island, Portugal.

artículo científico publicado en 2015

Inhibition of LOX by flavonoids: a structure-activity relationship study

artículo científico publicado en 2013

Insufficient referral for genetic counseling in the management of hereditary haemochromatosis in portugal: a study of perceptions of health professionals requesting HFE genotyping

artículo científico publicado en 2014

Interaction of polyacrylic acid coated and non-coated iron oxide nanoparticles with human neutrophils.

artículo científico publicado en 2013

Intracellular iron uptake is favored in Hfe-KO mouse primary chondrocytes mimicking an osteoarthritis-related phenotype

artículo científico publicado en 2019

Invariant Natural Killer T Cells are Reduced in Hereditary Hemochromatosis Patients

artículo científico publicado en 2014

Involvement of the major histocompatibility complex region in the genetic regulation of circulating CD8 T-cell numbers in humans.

artículo científico publicado en 2004

Iron homeostasis in breast cancer

artículo científico publicado en 2014

Iron overload in β2-microglobulin-deficient mice

artículo científico publicado en 1994

Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis

artículo científico publicado en 2018

Isolation and activation of human neutrophils in vitro. The importance of the anticoagulant used during blood collection

artículo científico publicado en 2008

Liver transplantation and anemia in familial amyloidosis ATTR V30M

scientific article published on 01 March 2007

Local iron homeostasis in the breast ductal carcinoma microenvironment

artículo científico publicado en 2016

Long-term treatment of anemia with recombinant human erythropoietin in familial amyloidosis TTR V30M.

artículo científico publicado en 2008

Low erythropoietin production in familial amyloidosis TTR V30M is not related with renal congophilic amyloid deposition. A clinicopathologic study of twelve cases.

artículo científico publicado en 2008

Low numbers of CD8+ T lymphocytes in hereditary haemochromatosis are explained by a decrease of the most mature CD8+ effector memory T cells.

artículo científico publicado en 2009

Low serum levels of prohepcidin, but not hepcidin-25, are related to anemia in familial amyloidosis TTR V30M.

artículo científico publicado en 2008

Low serum transferrin levels in HFE C282Y homozygous subjects are associated with low CD8+ T lymphocyte numbers

artículo científico publicado en 2005

Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivo

artículo científico publicado en 2015

Major histocompatibility complex class I associations in iron overload: evidence for a new link between the HFE H63D mutation, HLA-A29, and non-classical forms of hemochromatosis

artículo científico publicado en 1998

Modulation of human neutrophils' oxidative burst by flavonoids

artículo científico publicado en 2013

Nickel induces oxidative burst, NF-κB activation and interleukin-8 production in human neutrophils

artículo científico publicado en 2010

Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species

artículo científico publicado en 2013

Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin

scientific article published on 13 May 2019

Optimization of experimental settings for the analysis of human neutrophils oxidative burst in vitro

artículo científico publicado en 2009

Optimizing the management of hereditary haemochromatosis: the value of MRI R2* quantification to predict and monitor body iron stores.

artículo científico publicado en 2017

Physiological implications of NTBI uptake by T lymphocytes

artículo científico publicado en 2014

Polyacrylic acid coated and non-coated iron oxide nanoparticles are not genotoxic to human T lymphocytes

artículo científico publicado en 2015

Polyacrylic acid-coated and non-coated iron oxide nanoparticles induce cytokine activation in human blood cells through TAK1, p38 MAPK and JNK pro-inflammatory pathways.

artículo científico publicado en 2014

Prevalence of the C282Y and H63D mutations in the HFE gene in patients with hereditary haemochromatosis and in control subjects from Northern Germany

artículo científico publicado en 1998

Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals

artículo científico publicado en 2013

Protective role of calreticulin in HFE hemochromatosis

artículo científico publicado en 2007

Red blood cells inhibit activation-induced cell death and oxidative stress in human peripheral blood T lymphocytes.

artículo científico publicado en 2001

Red blood cells promote survival and cell cycle progression of human peripheral blood T cells independently of CD58/LFA-3 and heme compounds

artículo científico publicado en 2003

Red blood cells upregulate cytoprotective proteins and the labile iron pool in dividing human T cells despite a reduction in oxidative stress.

artículo científico publicado en 2003

Strengthening the perception-assessment tools for dengue prevention: a cross-sectional survey in a temperate region (Madeira, Portugal)

artículo científico publicado en 2014

T Cell Numbers Relate to Bone Involvement in Gaucher Disease

artículo científico publicado en 1999

T-Cell receptor repertoire in hereditary hemochromatosis: a study of 32 hemochromatosis patients and 274 healthy subjects

artículo científico publicado en 2001

The gel test: some problems and solutions

artículo científico publicado en 1992

The importance of the general practitioner as an information source for patients with hereditary haemochromatosis.

artículo científico publicado en 2014

Tissue iron quantification in chronic liver diseases using MRI shows a relationship between iron accumulation in liver, spleen, and bone marrow.

artículo científico publicado en 2017

Transferrin receptor 2 (TfR2) and HFE mutational analysis in non-C282Y iron overload: identification of a novel TfR2 mutation

artículo científico publicado en 2002

Trihydroxyflavones with antioxidant and anti-inflammatory efficacy

artículo científico publicado en 2012

Two novel mutations in the tmprss6 gene associated with iron-refractory iron-deficiency anaemia (irida) and partial expression in the heterozygous form

article

Zinc activates neutrophils' oxidative burst.

artículo científico publicado en 2009

Lista de obras de Graça Porto

A Portuguese patient homozygous for the -25G>A mutation of the HAMP promoter shows evidence of steady-state transcription but fails to up-regulate hepcidin levels by iron

A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts a less severe expression of hereditary hemochromatosis.

A novel mutation in the CUB sequence of matriptase-2 (TMPRSS6) is implicated in iron-resistant iron deficiency anaemia -- response to Jaspers et al.

A putative gene located at the MHC class I region around the D6S105 marker contributes to the setting of CD8+ T-lymphocyte numbers in humans.

Accurate simultaneous quantification of liver steatosis and iron overload in diffuse liver diseases with MRI.

Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils

CAT53 and HFE alleles in Alzheimer's disease: a putative protective role of the C282Y HFE mutation

Calreticulin Is Expressed on the Cell Surface of Activated Human Peripheral Blood T Lymphocytes in Association with Major Histocompatibility Complex Class I Molecules

Co-selection of the H63D mutation and the HLA-A29 allele: a new paradigm of linkage disequilibrium?

Comparative study between Hfe-/- and beta2m-/- mice: progression with age of iron status and liver pathology

Correction: Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis

Decreased CD8-p561ck Activity in Peripheral Blood T-Lymphocytes from Patients with Hereditary Haemochromatosis

EMQN best practice guidelines for the molecular genetic diagnosis of hereditary hemochromatosis (HH).

Effects of highly conserved major histocompatibility complex (MHC) extended haplotypes on iron and low CD8+ T lymphocyte phenotypes in HFE C282Y homozygous hemochromatosis patients from three geographically distant areas

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha

Expression of iron-related proteins in feline and canine mammary gland reveals unexpected accumulation of iron

Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation

Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis

HFE Related Hemochromatosis: Uncovering the Inextricable Link between Iron Homeostasis and the Immunological System

HFE Variants and the Expression of Iron-Related Proteins in Breast Cancer-Associated Lymphocytes and Macrophages

HFE mutations in the pathobiology of hemophilic arthropathy

Hemochromatosis and pregnancy: iron stores in the Hfe-/- mouse are not reduced by multiple pregnancies.

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

Hepcidin messenger RNA expression in human lymphocytes

Impact of a dengue outbreak experience in the preventive perceptions of the community from a temperate region: Madeira Island, Portugal.

Inhibition of LOX by flavonoids: a structure-activity relationship study

Insufficient referral for genetic counseling in the management of hereditary haemochromatosis in portugal: a study of perceptions of health professionals requesting HFE genotyping

Interaction of polyacrylic acid coated and non-coated iron oxide nanoparticles with human neutrophils.

Intracellular iron uptake is favored in Hfe-KO mouse primary chondrocytes mimicking an osteoarthritis-related phenotype

Invariant Natural Killer T Cells are Reduced in Hereditary Hemochromatosis Patients

Involvement of the major histocompatibility complex region in the genetic regulation of circulating CD8 T-cell numbers in humans.

Iron homeostasis in breast cancer

Iron overload in β2-microglobulin-deficient mice

Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis

Isolation and activation of human neutrophils in vitro. The importance of the anticoagulant used during blood collection

Liver transplantation and anemia in familial amyloidosis ATTR V30M

Local iron homeostasis in the breast ductal carcinoma microenvironment

Long-term treatment of anemia with recombinant human erythropoietin in familial amyloidosis TTR V30M.

Low erythropoietin production in familial amyloidosis TTR V30M is not related with renal congophilic amyloid deposition. A clinicopathologic study of twelve cases.

Low numbers of CD8+ T lymphocytes in hereditary haemochromatosis are explained by a decrease of the most mature CD8+ effector memory T cells.

Low serum levels of prohepcidin, but not hepcidin-25, are related to anemia in familial amyloidosis TTR V30M.

Low serum transferrin levels in HFE C282Y homozygous subjects are associated with low CD8+ T lymphocyte numbers

Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivo

Major histocompatibility complex class I associations in iron overload: evidence for a new link between the HFE H63D mutation, HLA-A29, and non-classical forms of hemochromatosis

Modulation of human neutrophils' oxidative burst by flavonoids

Nickel induces oxidative burst, NF-κB activation and interleukin-8 production in human neutrophils

Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species

Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin

Optimization of experimental settings for the analysis of human neutrophils oxidative burst in vitro

Optimizing the management of hereditary haemochromatosis: the value of MRI R2* quantification to predict and monitor body iron stores.

Physiological implications of NTBI uptake by T lymphocytes

Polyacrylic acid coated and non-coated iron oxide nanoparticles are not genotoxic to human T lymphocytes

Polyacrylic acid-coated and non-coated iron oxide nanoparticles induce cytokine activation in human blood cells through TAK1, p38 MAPK and JNK pro-inflammatory pathways.

Prevalence of the C282Y and H63D mutations in the HFE gene in patients with hereditary haemochromatosis and in control subjects from Northern Germany

Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals

Protective role of calreticulin in HFE hemochromatosis

Red blood cells inhibit activation-induced cell death and oxidative stress in human peripheral blood T lymphocytes.

Red blood cells promote survival and cell cycle progression of human peripheral blood T cells independently of CD58/LFA-3 and heme compounds

Red blood cells upregulate cytoprotective proteins and the labile iron pool in dividing human T cells despite a reduction in oxidative stress.

Strengthening the perception-assessment tools for dengue prevention: a cross-sectional survey in a temperate region (Madeira, Portugal)

T Cell Numbers Relate to Bone Involvement in Gaucher Disease

T-Cell receptor repertoire in hereditary hemochromatosis: a study of 32 hemochromatosis patients and 274 healthy subjects

The gel test: some problems and solutions

The importance of the general practitioner as an information source for patients with hereditary haemochromatosis.

Tissue iron quantification in chronic liver diseases using MRI shows a relationship between iron accumulation in liver, spleen, and bone marrow.

Transferrin receptor 2 (TfR2) and HFE mutational analysis in non-C282Y iron overload: identification of a novel TfR2 mutation

Trihydroxyflavones with antioxidant and anti-inflammatory efficacy

Two novel mutations in the tmprss6 gene associated with iron-refractory iron-deficiency anaemia (irida) and partial expression in the heterozygous form

Zinc activates neutrophils' oxidative burst.