Lista de obras - Michel Simon - Dominio Público Uruguay

A 4.2 kb upstream region of the human corneodesmosin gene directs site-specific expression in hair follicles and hyperkeratotic epidermis of transgenic mice

artículo científico publicado en 2004

A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin.

artículo científico publicado en 2010

Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis

artículo científico publicado en 2015

Alterations in the desquamation-related proteolytic cleavage of corneodesmosin and other corneodesmosomal proteins in psoriatic lesional epidermis

artículo científico publicado en 2008

An intronic enhancer driven by NF-κB contributes to transcriptional regulation of peptidylarginine deiminase type I gene in human keratinocytes.

artículo científico publicado en 2010

Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.

artículo científico publicado en 2014

Corneodesmosin, a Component of Epidermal Corneocyte Desmosomes, Displays Homophilic Adhesive Properties ⬇️

artículo científico publicado el 5 de diciembre de 2001

Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses.

scientific article published on May 2011

Corrigendum to: Defects of corneocyte structural proteins and epidermal barrier in atopic dermatitis.

artículo científico publicado en 2016

Crucial roles of MZF1 and Sp1 in the transcriptional regulation of the peptidylarginine deiminase type I gene (PADI1) in human keratinocytes.

artículo científico publicado en 2007

Defects of corneocyte structural proteins and epidermal barrier in atopic dermatitis

artículo científico publicado en 2015

Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin ⬇️

artículo científico publicado el 10 de febrero de 2013

Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases

scientific article published on 15 January 2020

Deimination and expression of peptidylarginine deiminases during cutaneous wound healing in mice

scientific article published on 01 May 2011

Deimination is regulated at multiple levels including auto-deimination of peptidylarginine deiminases.

artículo científico publicado en 2010

Deimination of Human Hornerin Enhances its Processing by Calpain-1 and its Cross-Linking by Transglutaminases

artículo científico publicado en 2016

Deimination of human filaggrin-2 promotes its proteolysis by calpain 1

scientific journal article

Deimination, Intermediate Filaments and Associated Proteins

artículo científico publicado en 2020

Effects of environmental skin stressors on filaggrin degradation products: importance for eczema

artículo científico publicado en 2018

Expression pattern of peptidylarginine deiminase in rat and human Schwann cells.

artículo científico publicado en 2008

Expression profile of cornified envelope structural proteins and keratinocyte differentiation-regulating proteins during skin barrier repair.

artículo científico publicado en 2012

Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice

artículo científico publicado en 2019

Filaggrin is expressed in the epithelial cells of the buccal mucosae

scientific article published on 24 September 2014

High TMEM45A expression is correlated to epidermal keratinization.

artículo científico publicado en 2014

Hornerin is a component of the epidermal cornified cell envelopes ⬇️

artículo científico publicado el 31 de enero de 2011

Hyaluronan Does Not Regulate Human Epidermal Keratinocyte Proliferation and Differentiation

artículo científico publicado en 2015

In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification

artículo científico publicado en 2015

In vivo quantification of epidermis pigmentation and dermis papilla density with reflectance confocal microscopy: variations with age and skin phototype ⬇️

artículo científico publicado el 1 de abril de 2012

Knockdown of filaggrin in a three-dimensional reconstructed human epidermis impairs keratinocyte differentiation

scientific article published on 13 June 2014

Lamellar bodies of human epidermis: proteomics characterization by high throughput mass spectrometry and possible involvement of CLIP-170 in their trafficking/secretion

artículo científico publicado en 2008

Latent class analysis categorises chronic hand eczema patients according to skin barrier impairment

scientific article published on 17 November 2019

Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte

artículo científico publicado en 2008

Long-range enhancer differentially regulated by c-Jun and JunD controls peptidylarginine deiminase-3 gene in keratinocytes.

artículo científico publicado en 2008

Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome

scientific journal article

NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes

artículo científico publicado en 2006

Nine procaspases are expressed in normal human epidermis, but only caspase-14 is fully processed

scientific article published on 01 March 2007

Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation

artículo científico publicado en 2007

Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis

artículo científico publicado en 2019

Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin.

artículo científico publicado en 2005

Peptidylarginine deiminase isoforms are differentially expressed in the anagen hair follicles and other human skin appendages

artículo científico publicado en 2005

Peptidylarginine deiminases and deiminated proteins at the epidermal barrier

artículo científico publicado en 2018

Peptidylarginine deiminases and deimination in biology and pathology: relevance to skin homeostasis.

artículo científico publicado en 2006

Positive change in hand care habits using therapeutic patient education in chronic hand eczema

scientific article published on 07 October 2019

Protease sensitivity of corneodesmosin variants encoded by the six more common CDSN haplotypes

artículo científico publicado en 2011

Rab11a Is Essential for Lamellar Body Biogenesis in the Human Epidermis.

artículo científico publicado en 2016

Refined Immunochemical Characterization in Healthy Dog Skin of the Epidermal Cornification Proteins, Filaggrin, and Corneodesmosin

scientific article published on 10 September 2018

Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors.

artículo científico publicado en 2005

Skin barrier in atopic dermatitis.

artículo científico

Stabilization of microtubules restores barrier function after cytokine-induced defects in reconstructed human epidermis

artículo científico publicado en 2018

Staphylococcus aureus density on lesional and nonlesional skin is strongly associated with disease severity in atopic dermatitis

artículo científico publicado en 2015

The 3′-UTR AACCins5874 in the stratum corneum chymotryptic enzyme gene (SCCE/KLK7), associated with atopic dermatitis; causes an increased mRNA expression without altering its stability

artículo científico publicado en 2011

The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity

artículo científico publicado en 2019

The Amino-Terminal Part of Human FLG2 Is a Component of Cornified Envelopes

scientific article published on 05 December 2018

The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations.

artículo científico publicado en 2005

Topographical and nano-mechanical characterization of native corneocytes using atomic force microscopy

artículo científico publicado en 2014

Update on peptidylarginine deiminases and deimination in skin physiology and severe human diseases.

artículo científico publicado en 2007

Update on the epidermal differentiation complex.

artículo científico publicado en 2012

Variant PADI3 in Central Centrifugal Cicatricial Alopecia

scientific article published on 13 February 2019

Lista de obras de Michel Simon

A 4.2 kb upstream region of the human corneodesmosin gene directs site-specific expression in hair follicles and hyperkeratotic epidermis of transgenic mice

A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin.

Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis

Alterations in the desquamation-related proteolytic cleavage of corneodesmosin and other corneodesmosomal proteins in psoriatic lesional epidermis

An intronic enhancer driven by NF-κB contributes to transcriptional regulation of peptidylarginine deiminase type I gene in human keratinocytes.

Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.

Corneodesmosin, a Component of Epidermal Corneocyte Desmosomes, Displays Homophilic Adhesive Properties ⬇️

Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses.

Corrigendum to: Defects of corneocyte structural proteins and epidermal barrier in atopic dermatitis.

Crucial roles of MZF1 and Sp1 in the transcriptional regulation of the peptidylarginine deiminase type I gene (PADI1) in human keratinocytes.

Defects of corneocyte structural proteins and epidermal barrier in atopic dermatitis

Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin ⬇️

Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases

Deimination and expression of peptidylarginine deiminases during cutaneous wound healing in mice

Deimination is regulated at multiple levels including auto-deimination of peptidylarginine deiminases.

Deimination of Human Hornerin Enhances its Processing by Calpain-1 and its Cross-Linking by Transglutaminases

Deimination of human filaggrin-2 promotes its proteolysis by calpain 1

Deimination, Intermediate Filaments and Associated Proteins

Effects of environmental skin stressors on filaggrin degradation products: importance for eczema

Expression pattern of peptidylarginine deiminase in rat and human Schwann cells.

Expression profile of cornified envelope structural proteins and keratinocyte differentiation-regulating proteins during skin barrier repair.

Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice

Filaggrin is expressed in the epithelial cells of the buccal mucosae

High TMEM45A expression is correlated to epidermal keratinization.

Hornerin is a component of the epidermal cornified cell envelopes ⬇️

Hyaluronan Does Not Regulate Human Epidermal Keratinocyte Proliferation and Differentiation

In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification

In vivo quantification of epidermis pigmentation and dermis papilla density with reflectance confocal microscopy: variations with age and skin phototype ⬇️

Knockdown of filaggrin in a three-dimensional reconstructed human epidermis impairs keratinocyte differentiation

Lamellar bodies of human epidermis: proteomics characterization by high throughput mass spectrometry and possible involvement of CLIP-170 in their trafficking/secretion

Latent class analysis categorises chronic hand eczema patients according to skin barrier impairment

Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte

Long-range enhancer differentially regulated by c-Jun and JunD controls peptidylarginine deiminase-3 gene in keratinocytes.

Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome

NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes

Nine procaspases are expressed in normal human epidermis, but only caspase-14 is fully processed

Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation

Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis

Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin.

Peptidylarginine deiminase isoforms are differentially expressed in the anagen hair follicles and other human skin appendages

Peptidylarginine deiminases and deiminated proteins at the epidermal barrier

Peptidylarginine deiminases and deimination in biology and pathology: relevance to skin homeostasis.

Positive change in hand care habits using therapeutic patient education in chronic hand eczema

Protease sensitivity of corneodesmosin variants encoded by the six more common CDSN haplotypes

Rab11a Is Essential for Lamellar Body Biogenesis in the Human Epidermis.

Refined Immunochemical Characterization in Healthy Dog Skin of the Epidermal Cornification Proteins, Filaggrin, and Corneodesmosin

Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors.

Skin barrier in atopic dermatitis.

Stabilization of microtubules restores barrier function after cytokine-induced defects in reconstructed human epidermis

Staphylococcus aureus density on lesional and nonlesional skin is strongly associated with disease severity in atopic dermatitis

The 3′-UTR AACCins5874 in the stratum corneum chymotryptic enzyme gene (SCCE/KLK7), associated with atopic dermatitis; causes an increased mRNA expression without altering its stability

The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity

The Amino-Terminal Part of Human FLG2 Is a Component of Cornified Envelopes

The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations.

Topographical and nano-mechanical characterization of native corneocytes using atomic force microscopy

Update on peptidylarginine deiminases and deimination in skin physiology and severe human diseases.

Update on the epidermal differentiation complex.

Variant PADI3 in Central Centrifugal Cicatricial Alopecia