Lista de obras - Ross D Hannan - Dominio Público Uruguay

A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells.

artículo científico publicado en 2011

A functional genetic screen defines the AKT-induced senescence signaling network

scientific article published on 08 July 2019

A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.

artículo científico publicado en 2013

A novel mouse model of atherosclerotic plaque instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling

artículo científico publicado en 2013

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes

artículo científico publicado en 2014

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

scientific article published on 22 January 2019

A specific role for AKT3 in the genesis of ovarian cancer through modulation of G(2)-M phase transition

artículo científico publicado en 2006

AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer

artículo científico publicado en 2011

AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-Myc B-cell lymphoma in vivo

artículo científico publicado en 2013

AKT-independent PI3-K signaling in cancer - emerging role for SGK3.

artículo científico publicado en 2013

Adenovirus-mediated delivery of relaxin reverses cardiac fibrosis

artículo científico publicado en 2007

Adrenergic agents, but not triiodo-L-thyronine induce c-fos and c-myc expression in the rat heart

artículo científico publicado en 1991

Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription

artículo científico publicado en 2016

An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF

artículo científico publicado en 2001

Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis

artículo científico publicado en 2013

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

scientific article published on 26 May 2020

Cardiac hypertrophy in vivo is associated with increased expression of the ribosomal gene transcription factor UBF.

artículo científico publicado en 2003

Cardiac hypertrophy: a matter of translation.

artículo científico publicado en 2003

Cardiovascular role of urotensin II: effect of chronic infusion in the rat.

artículo científico publicado en 2004

Cellular regulation of ribosomal DNA transcription:both rat and Xenopus UBF1 stimulate rDNA transcription in 3T3 fibroblasts

artículo científico publicado en 1999

Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere

artículo científico publicado en 2007

Chromatin organization and expression

artículo científico publicado en 2008

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

artículo científico publicado en 2015

Combined angiotensin and endothelin receptor blockade attenuates adverse cardiac remodeling post-myocardial infarction in the rat: possible role of transforming growth factor beta(1).

artículo científico publicado en 2001

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas

artículo científico publicado en 2013

Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor body

artículo científico publicado en 2014

Cross talk between corticosteroids and alpha-adrenergic signalling augments cardiomyocyte hypertrophy: a possible role for SGK1.

artículo científico publicado en 2006

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models

artículo científico publicado en 2015

Dysregulation of the basal RNA polymerase transcription apparatus in cancer

artículo científico

Expression of c-fos and related genes in the rat heart in response to norepinephrine.

artículo científico publicado en 1993

Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart

artículo científico publicado en 2013

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study

artículo científico publicado en 2019

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

artículo científico publicado en 2015

Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner

artículo científico publicado en 2010

Hfp, the Drosophila homolog of the mammalian c-myc transcriptional-repressor and tumor suppressor FIR, inhibits dmyc transcription and cell growth.

artículo científico publicado en 2011

Hijacking epidermal growth factor receptors by angiotensin II: new possibilities for understanding and treating cardiac hypertrophy.

artículo científico publicado en 2004

Identification of a mammalian RNA polymerase I holoenzyme containing components of the DNA repair/replication system.

artículo científico publicado en 1999

Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer.

artículo científico publicado en 2015

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

artículo científico publicado en 2017

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

artículo científico publicado en 2016

Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor

artículo científico publicado en 2002

Localization of c-myc protooncogene expression in the rat heart in vivo and in the isolated, perfused heart following treatment with norepinephrine

artículo científico publicado en 1994

MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

artículo científico publicado en 2004

Migration of Small Ribosomal Subunits on the 5' Untranslated Regions of Capped Messenger RNA

artículo científico publicado en 2019

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity

artículo científico publicado en 2015

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity.

artículo científico publicado en 2014

Proliferation of neointimal smooth muscle cells after arterial injury. Dependence on interactions between fibroblast growth factor receptor-2 and fibroblast growth factor-9

scientific journal article

Regulation of rDNA transcription factors during cardiomyocyte hypertrophy induced by adrenergic agents

scientific article published on 01 April 1995

Regulation of rDNA transcription in response to growth factors, nutrients and energy

artículo científico publicado en 2014

Regulation of ribosomal DNA transcription during contraction-induced hypertrophy of neonatal cardiomyocytes.

artículo científico publicado en 1996

Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression

artículo científico publicado en 2020

Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitors

artículo científico publicado en 2013

Targeting RNA polymerase I to treat MYC-driven cancer.

artículo científico publicado en 2014

Targeting RNA polymerase I transcription and the nucleolus for cancer therapy

artículo científico publicado en 2013

Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.

artículo científico publicado en 2010

Targeting the nucleolus for cancer-specific activation of p53.

artículo científico publicado en 2013

The 'Odd Pols' are even when it comes to controlling cell function. Conference on RNA Polymerases I and III.

artículo científico publicado en 2008

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

scientific article published on 11 November 2020

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35

artículo científico publicado en 2019

The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence

artículo científico publicado en 2012

The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy

artículo científico publicado en 2014

The renin-angiotensin system and cancer: old dog, new tricks.

artículo científico publicado en 2010

Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation

artículo científico publicado en 2008

Urotensin II promotes hypertrophy of cardiac myocytes via mitogen-activated protein kinases

artículo científico publicado en 2004

Urotensin II: the old kid in town.

artículo científico publicado en 2004

Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells

artículo científico publicado en 2014

Lista de obras de Ross D Hannan

A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells.

A functional genetic screen defines the AKT-induced senescence signaling network

A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.

A novel mouse model of atherosclerotic plaque instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

A specific role for AKT3 in the genesis of ovarian cancer through modulation of G(2)-M phase transition

AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer

AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-Myc B-cell lymphoma in vivo

AKT-independent PI3-K signaling in cancer - emerging role for SGK3.

Adenovirus-mediated delivery of relaxin reverses cardiac fibrosis

Adrenergic agents, but not triiodo-L-thyronine induce c-fos and c-myc expression in the rat heart

Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription

An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF

Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Cardiac hypertrophy in vivo is associated with increased expression of the ribosomal gene transcription factor UBF.

Cardiac hypertrophy: a matter of translation.

Cardiovascular role of urotensin II: effect of chronic infusion in the rat.

Cellular regulation of ribosomal DNA transcription:both rat and Xenopus UBF1 stimulate rDNA transcription in 3T3 fibroblasts

Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere

Chromatin organization and expression

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

Combined angiotensin and endothelin receptor blockade attenuates adverse cardiac remodeling post-myocardial infarction in the rat: possible role of transforming growth factor beta(1).

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas

Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor body

Cross talk between corticosteroids and alpha-adrenergic signalling augments cardiomyocyte hypertrophy: a possible role for SGK1.

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models

Dysregulation of the basal RNA polymerase transcription apparatus in cancer

Expression of c-fos and related genes in the rat heart in response to norepinephrine.

Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner

Hfp, the Drosophila homolog of the mammalian c-myc transcriptional-repressor and tumor suppressor FIR, inhibits dmyc transcription and cell growth.

Hijacking epidermal growth factor receptors by angiotensin II: new possibilities for understanding and treating cardiac hypertrophy.

Identification of a mammalian RNA polymerase I holoenzyme containing components of the DNA repair/replication system.

Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer.

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor

Localization of c-myc protooncogene expression in the rat heart in vivo and in the isolated, perfused heart following treatment with norepinephrine

MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

Migration of Small Ribosomal Subunits on the 5' Untranslated Regions of Capped Messenger RNA

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity.

Proliferation of neointimal smooth muscle cells after arterial injury. Dependence on interactions between fibroblast growth factor receptor-2 and fibroblast growth factor-9

Regulation of rDNA transcription factors during cardiomyocyte hypertrophy induced by adrenergic agents

Regulation of rDNA transcription in response to growth factors, nutrients and energy

Regulation of ribosomal DNA transcription during contraction-induced hypertrophy of neonatal cardiomyocytes.

Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression

Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitors

Targeting RNA polymerase I to treat MYC-driven cancer.

Targeting RNA polymerase I transcription and the nucleolus for cancer therapy

Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.

Targeting the nucleolus for cancer-specific activation of p53.

The 'Odd Pols' are even when it comes to controlling cell function. Conference on RNA Polymerases I and III.

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35

The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence

The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy

The renin-angiotensin system and cancer: old dog, new tricks.

Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation

Urotensin II promotes hypertrophy of cardiac myocytes via mitogen-activated protein kinases

Urotensin II: the old kid in town.

Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells