Lista de obras - Jiří Klimeš - Dominio Público Uruguay

A model of natural degradation of 17-α-ethinylestradiol in surface water and identification of degradation products by GC-MS.

artículo científico publicado en 2017

An innovative approach to the analysis of 3-[4-(2-methylpropyl)phenyl]propanoic acid as an impurity of ibuprofen on a carbon-coated zirconia stationary phase.

artículo científico publicado en 2009

Combination of molecular modeling and quantitative structure-activity relationship analysis in the study of antimycobacterial activity of pyridine derivatives

artículo científico publicado en 2000

Comparison of different stationary phases for bioanalytical studies of biologically active compounds

artículo científico publicado en 2006

Determination of ibuprofen in erythrocytes and plasma by high performance liquid chromatography

artículo científico publicado en 1995

Determination of lipophilicity of novel potential antituberculotic agents using HPLC on monolithic stationary phase and theoretical calculations

artículo científico publicado en 2008

Development and validation of HPLC-DAD methods for the analysis of two novel iron chelators with potent anti-cancer activity

artículo científico publicado en 2006

Development of LC-MS/MS method for the simultaneous analysis of the cardioprotective drug dexrazoxane and its metabolite ADR-925 in isolated cardiomyocytes and cell culture medium

artículo científico publicado en 2012

Development of an LC-MS/MS method for analysis of interconvertible Z/E isomers of the novel anticancer agent, Bp4eT.

artículo científico publicado en 2010

Development of high-performance liquid chromatographic determination of salicylaldehyde isonicotinoyl hydrazone in rabbit plasma and application of this method to an in vivo study

artículo científico publicado en 2005

Dinaciclib, a cyclin-dependent kinase inhibitor, is a substrate of human ABCB1 and ABCG2 and an inhibitor of human ABCC1 in vitro.

artículo científico publicado en 2015

Disposition study of a new potential antineoplastic agent dimefluron in rats using high-performance liquid chromatography with ultraviolet and mass spectrometric detection.

artículo científico publicado en 2005

HPLC determination of a novel aroylhydrazone iron chelator (o-108) in rabbit plasma and its application to a pilot pharmacokinetic study

artículo científico publicado en 2006

HPLC evaluation of diclofenac in transdermal therapeutic preparations

artículo científico publicado en 2001

HPLC methods for determination of two novel thiosemicarbazone anti-cancer drugs (N4mT and Dp44mT) in plasma and their application to in vitro plasma stability of these agents

artículo científico publicado en 2008

HPLC study of glimepiride under hydrolytic stress conditions

artículo científico publicado en 2004

HPLC study on stability of pyridoxal isonicotinoyl hydrazone.

artículo científico publicado en 2005

HPLC-DAD and MS/MS analysis of novel drug candidates from the group of aromatic hydrazones revealing the presence of geometric isomers

artículo científico publicado en 2007

High-performance liquid chromatographic assay for ibuprofen in whole blood using solid-phase extraction

artículo científico publicado en 1994

High-performance liquid chromatographic determination of terguride in solid dosage forms and plasma

scientific article published on 01 January 1995

High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples

artículo científico publicado en 2007

Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites--the cardioprotectant dexrazoxane as a model case.

artículo científico publicado en 2010

Identification of in vitro metabolites of the novel anti-tumor thiosemicarbazone, DpC, using ultra-high performance liquid chromatography–quadrupole-time-of-flight mass spectrometry

artículo científico publicado en 2012

Investigation of the stability of aromatic hydrazones in plasma and related biological material.

artículo científico publicado en 2008

LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT.

artículo científico publicado en 2012

LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)

artículo científico publicado en 2014

Microcolumn high-performance liquid chromatographic assay for doxycycline in isolated alveolar macrophages

artículo científico publicado en 1999

Olomoucine II, but not purvalanol A, is transported by breast cancer resistance protein (ABCG2) and P-glycoprotein (ABCB1)

artículo científico publicado en 2013

Optimization of HPLC chromatographic conditions for determination of Transkarbam 12 and its degradation products

artículo científico publicado en 2006

Photochemical stability of nimesulide.

artículo científico publicado en 2003

Placental passage of olomoucine II, but not purvalanol A, is affected by p-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2) and multidrug resistance-associated proteins (ABCCs).

artículo científico publicado en 2015

Potential employment of non-silica-based stationary phases in pharmaceutical analysis

artículo científico publicado en 2007

Preliminary pharmaceutico-analytical evaluation of transkarbam 12 using liquid chromatography

artículo científico publicado en 2006

Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: application to a pilot pharmacokinetic study in rats

artículo científico publicado en 2013

Stability of ramipril in the solvents of different pH.

artículo científico publicado en 2005

The influence of a carbon layer deposited on a zirconia surface on the retention of polar analytes in an organic rich mobile phase

scientific article published on 27 December 2011

The retention behaviour of polar compounds on zirconia based stationary phases under hydrophilic interaction liquid chromatography conditions

artículo científico publicado en 2011

Titania-based stationary phase in separation of ondansetron and its related compounds.

artículo científico publicado en 2007

Use of chiral liquid chromatography for the evaluation of stereospecificity in the carbonyl reduction of potential benzo[c]fluorene antineoplastics benfluron and dimefluron in various species.

artículo científico publicado en 2004

Use of different stationary phases for separation of isoniazid, its metabolites and vitamin B6 forms

artículo científico publicado en 2011

Use of the zirconia-based stationary phase for separation of ibuprofen and its impurities

artículo científico publicado en 2005

Using of HPLC coupled with coulometric detector for the determination of biotin in pharmaceuticals.

artículo científico publicado en 2007

Utilization of zirconia stationary phase as a tool in drug control.

artículo científico publicado en 2005

Zirconia--a stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography

artículo científico publicado en 2014

Lista de obras de Jiří Klimeš

A model of natural degradation of 17-α-ethinylestradiol in surface water and identification of degradation products by GC-MS.

An innovative approach to the analysis of 3-[4-(2-methylpropyl)phenyl]propanoic acid as an impurity of ibuprofen on a carbon-coated zirconia stationary phase.

Combination of molecular modeling and quantitative structure-activity relationship analysis in the study of antimycobacterial activity of pyridine derivatives

Comparison of different stationary phases for bioanalytical studies of biologically active compounds

Determination of ibuprofen in erythrocytes and plasma by high performance liquid chromatography

Determination of lipophilicity of novel potential antituberculotic agents using HPLC on monolithic stationary phase and theoretical calculations

Development and validation of HPLC-DAD methods for the analysis of two novel iron chelators with potent anti-cancer activity

Development of LC-MS/MS method for the simultaneous analysis of the cardioprotective drug dexrazoxane and its metabolite ADR-925 in isolated cardiomyocytes and cell culture medium

Development of an LC-MS/MS method for analysis of interconvertible Z/E isomers of the novel anticancer agent, Bp4eT.

Development of high-performance liquid chromatographic determination of salicylaldehyde isonicotinoyl hydrazone in rabbit plasma and application of this method to an in vivo study

Dinaciclib, a cyclin-dependent kinase inhibitor, is a substrate of human ABCB1 and ABCG2 and an inhibitor of human ABCC1 in vitro.

Disposition study of a new potential antineoplastic agent dimefluron in rats using high-performance liquid chromatography with ultraviolet and mass spectrometric detection.

HPLC determination of a novel aroylhydrazone iron chelator (o-108) in rabbit plasma and its application to a pilot pharmacokinetic study

HPLC evaluation of diclofenac in transdermal therapeutic preparations

HPLC methods for determination of two novel thiosemicarbazone anti-cancer drugs (N4mT and Dp44mT) in plasma and their application to in vitro plasma stability of these agents

HPLC study of glimepiride under hydrolytic stress conditions

HPLC study on stability of pyridoxal isonicotinoyl hydrazone.

HPLC-DAD and MS/MS analysis of novel drug candidates from the group of aromatic hydrazones revealing the presence of geometric isomers

High-performance liquid chromatographic assay for ibuprofen in whole blood using solid-phase extraction

High-performance liquid chromatographic determination of terguride in solid dosage forms and plasma

High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples

Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites--the cardioprotectant dexrazoxane as a model case.

Identification of in vitro metabolites of the novel anti-tumor thiosemicarbazone, DpC, using ultra-high performance liquid chromatography–quadrupole-time-of-flight mass spectrometry

Investigation of the stability of aromatic hydrazones in plasma and related biological material.

LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT.

LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)

Microcolumn high-performance liquid chromatographic assay for doxycycline in isolated alveolar macrophages

Olomoucine II, but not purvalanol A, is transported by breast cancer resistance protein (ABCG2) and P-glycoprotein (ABCB1)

Optimization of HPLC chromatographic conditions for determination of Transkarbam 12 and its degradation products

Photochemical stability of nimesulide.

Placental passage of olomoucine II, but not purvalanol A, is affected by p-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2) and multidrug resistance-associated proteins (ABCCs).

Potential employment of non-silica-based stationary phases in pharmaceutical analysis

Preliminary pharmaceutico-analytical evaluation of transkarbam 12 using liquid chromatography

Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: application to a pilot pharmacokinetic study in rats

Stability of ramipril in the solvents of different pH.

The influence of a carbon layer deposited on a zirconia surface on the retention of polar analytes in an organic rich mobile phase

The retention behaviour of polar compounds on zirconia based stationary phases under hydrophilic interaction liquid chromatography conditions

Titania-based stationary phase in separation of ondansetron and its related compounds.

Use of chiral liquid chromatography for the evaluation of stereospecificity in the carbonyl reduction of potential benzo[c]fluorene antineoplastics benfluron and dimefluron in various species.

Use of different stationary phases for separation of isoniazid, its metabolites and vitamin B6 forms

Use of the zirconia-based stationary phase for separation of ibuprofen and its impurities

Using of HPLC coupled with coulometric detector for the determination of biotin in pharmaceuticals.

Utilization of zirconia stationary phase as a tool in drug control.

Zirconia--a stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography