Lista de obras - Saskia Nijmeijer - Dominio Público Uruguay

7TM Domain Structure of Adhesion GPCRs

artículo científico publicado en 2016

A structural insight into the reorientation of transmembrane domains 3 and 5 during family A G protein-coupled receptor activation

artículo científico publicado en 2010

Adhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms

artículo científico publicado en 2015

Adhesion GPCRs in immunology

artículo científico publicado en 2016

Analysis of multiple histamine H₄ receptor compound classes uncovers Gαi protein- and β-arrestin2-biased ligands

artículo científico publicado en 2012

Bispyrimidines as potent histamine H(4) receptor ligands: delineation of structure-activity relationships and detailed H(4) receptor binding mode

artículo científico publicado en 2013

Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs

artículo científico publicado en 2016

Combinatorial Consensus Scoring for Ligand-Based Virtual Fragment Screening: A Comparative Case Study for Serotonin 5-HT(3)A, Histamine H(1), and Histamine H(4) Receptors

artículo científico publicado en 2015

Constitutive activity of the histamine H(1) receptor

artículo científico publicado en 2010

Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 98(3.36) of the human histamine H₄ receptor.

artículo científico publicado en 2013

Detailed analysis of biased histamine H₄ receptor signalling by JNJ 7777120 analogues

artículo científico publicado en 2013

Development of a profiling strategy for metabolic mixtures by combining chromatography and mass spectrometry with cell-based GPCR signaling

artículo científico publicado en 2012

Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H₄ and the ion channel serotonin 5-HT₃A.

artículo científico publicado en 2011

G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand?

artículo científico publicado en 2011

High-resolution metabolic profiling towards G protein-coupled receptors: rapid and comprehensive screening of histamine H₄ receptor ligands.

artículo científico publicado en 2012

Mapping histamine H4receptor–ligand binding modes

Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies

artículo científico publicado en 2011

Molecular pharmacology of histamine H4 receptors

artículo científico

Real-time visualization of heterotrimeric G protein Gq activation in living cells

artículo científico publicado en 2011

Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US28.

artículo científico publicado en 2009

Small and colorful stones make beautiful mosaics: fragment-based chemogenomics

artículo científico publicado en 2012

Structure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H4 receptor

The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Gαi proteins, and constitutively impairs CXCR4 functioning

artículo científico publicado en 2010

The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human Chemokines

artículo científico publicado en 2015

Triazole Ligands Reveal Distinct Molecular Features That Induce Histamine H4Receptor Affinity and Subtly Govern H4/H3Subtype Selectivity

artículo científico publicado en 2011

Viral hijacking of human receptors through heterodimerization

artículo científico publicado en 2008

Virtual Fragment Screening: Discovery of Histamine H3 Receptor Ligands Using Ligand-Based and Protein-Based Molecular Fingerprints

artículo científico publicado en 2012

Lista de obras de Saskia Nijmeijer

7TM Domain Structure of Adhesion GPCRs

A structural insight into the reorientation of transmembrane domains 3 and 5 during family A G protein-coupled receptor activation

Adhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms

Adhesion GPCRs in immunology

Analysis of multiple histamine H₄ receptor compound classes uncovers Gαi protein- and β-arrestin2-biased ligands

Bispyrimidines as potent histamine H(4) receptor ligands: delineation of structure-activity relationships and detailed H(4) receptor binding mode

Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs

Combinatorial Consensus Scoring for Ligand-Based Virtual Fragment Screening: A Comparative Case Study for Serotonin 5-HT(3)A, Histamine H(1), and Histamine H(4) Receptors

Constitutive activity of the histamine H(1) receptor

Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 98(3.36) of the human histamine H₄ receptor.

Detailed analysis of biased histamine H₄ receptor signalling by JNJ 7777120 analogues

Development of a profiling strategy for metabolic mixtures by combining chromatography and mass spectrometry with cell-based GPCR signaling

Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H₄ and the ion channel serotonin 5-HT₃A.

G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand?

High-resolution metabolic profiling towards G protein-coupled receptors: rapid and comprehensive screening of histamine H₄ receptor ligands.

Mapping histamine H4receptor–ligand binding modes

Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies

Molecular pharmacology of histamine H4 receptors

Real-time visualization of heterotrimeric G protein Gq activation in living cells

Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US28.

Small and colorful stones make beautiful mosaics: fragment-based chemogenomics

Structure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H4 receptor

The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Gαi proteins, and constitutively impairs CXCR4 functioning

The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human Chemokines

Triazole Ligands Reveal Distinct Molecular Features That Induce Histamine H4Receptor Affinity and Subtly Govern H4/H3Subtype Selectivity

Viral hijacking of human receptors through heterodimerization

Virtual Fragment Screening: Discovery of Histamine H3 Receptor Ligands Using Ligand-Based and Protein-Based Molecular Fingerprints