Lista de obras - Mark S. Dillingham - Dominio Público Uruguay

A Single-Molecule Approach to Visualize the Unwinding Activity of DNA Helicases

artículo científico publicado en 2011

A dual-nuclease mechanism for DNA break processing by AddAB-type helicase-nucleases

artículo científico publicado en 2007

A molecular throttle: the recombination hotspot chi controls DNA translocation by the RecBCD helicase

artículo científico publicado en 2003

A new method for inferring hidden markov models from noisy time sequences

artículo científico publicado en 2012

A step backward in advancing DNA replication: rescue of stalled replication forks by RecG.

artículo científico publicado en 2001

AFM volumetric methods for the characterization of proteins and nucleic acids ⬇️

artículo científico publicado el 28 de febrero de 2013

Alteration of χ recognition by RecBCD reveals a regulated molecular latch and suggests a channel-bypass mechanism for biological control

artículo científico publicado en 2012

An iron-sulfur cluster is essential for the binding of broken DNA by AddAB-type helicase-nucleases

artículo científico publicado en 2009

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

scientific article published on 19 July 2021

Bipolar DNA translocation contributes to highly processive DNA unwinding by RecBCD enzyme

artículo científico publicado en 2005

Bulk and single-molecule analysis of a bacterial DNA2-like helicase-nuclease reveals a single-stranded DNA looping motor

artículo científico publicado en 2020

Chi hotspots trigger a conformational change in the helicase-like domain of AddAB to activate homologous recombination

artículo científico publicado en 2016

Crystal structure of RecBCD : a machine for processing DNA breaks

Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks

artículo científico publicado en 2004

Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism

artículo científico publicado en 1999

CtIP forms a tetrameric dumbbell-shaped particle which bridges complex DNA end structures for double-strand break repair

artículo científico publicado en 2019

DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase

artículo científico publicado en 1999

Demonstration of unidirectional single-stranded DNA translocation by PcrA helicase: measurement of step size and translocation speed

artículo científico publicado en 2000

Direct measurement of single-stranded DNA translocation by PcrA helicase using the fluorescent base analogue 2-aminopurine

artículo científico publicado en 2002

Directional Loading and Stimulation of PcrA Helicase by the Replication Initiator Protein RepD

artículo científico publicado en 2007

Engineering a reagentless biosensor for single-stranded DNA to measure real-time helicase activity in Bacillus

artículo científico publicado en 2014

Escherichia coli ribosomal protein L3 stimulates the helicase activity of the Bacillus stearothermophilus PcrA helicase.

artículo científico publicado en 1998

Fluorescent single-stranded DNA binding protein as a probe for sensitive, real-time assays of helicase activity

artículo científico publicado en 2008

Force determination in lateral magnetic tweezers combined with TIRF microscopy.

artículo científico publicado en 2018

Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus

artículo científico publicado en 2022

How to Build a DNA Unwinding Machine ⬇️

artículo científico publicado el 3 de julio de 2012

Human CtIP forms a tetrameric dumbbell-shaped particle which binds and bridges complex DNA end structures for double-strand break repair

Inhibiting translation elongation can aid genome duplication in Escherichia coli

artículo científico publicado en 2016

Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex

artículo científico publicado en 2012

Iron–sulphur clusters in nucleic acid processing enzymes ⬇️

artículo científico publicado el 12 de diciembre de 2011

Molecular determinants responsible for recognition of the single-stranded DNA regulatory sequence, χ, by RecBCD enzyme

artículo científico publicado en 2012

Monomeric PcrA helicase processively unwinds plasmid lengths of DNA in the presence of the initiator protein RepD.

artículo científico publicado en 2013

On the mechanism of recombination hotspot scanning during double-stranded DNA break resection

artículo científico publicado en 2013

ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements

artículo científico publicado en 2019

Probing DNA helicase kinetics with temperature-controlled magnetic tweezers

artículo científico publicado en 2014

Protein modification for single molecule fluorescence microscopy

scientific article published on 14 July 2008

RecBCD enzyme and the repair of double-stranded DNA breaks

artículo científico publicado en 2008

RecBCD enzyme is a bipolar DNA helicase

artículo científico publicado en 2003

Recombination Hotspots and Single-Stranded DNA Binding Proteins Couple DNA Translocation to DNA Unwinding by the AddAB Helicase-Nuclease

artículo científico publicado en 2011

Recombination hotspots attenuate the coupled ATPase and translocase activities of an AddAB-type helicase-nuclease

artículo científico publicado en 2014

Rep provides a second motor at the replisome to promote duplication of protein-bound DNA.

artículo científico publicado en 2009

Repercussions of DNA tracking by the type IC restriction endonuclease EcoR124I on linear, circular and catenated substrates.

artículo científico publicado en 1996

Replicative Helicases: A Staircase with a Twist

artículo científico publicado en 2006

Single molecule approaches to monitor the recognition and resection of double-stranded DNA breaks during homologous recombination

artículo científico publicado en 2014

Site-directed mutagenesis of motif III in PcrA helicase reveals a role in coupling ATP hydrolysis to strand separation.

artículo científico publicado en 1999

Specific and non-specific interactions of ParB with DNA: implications for chromosome segregation

artículo científico publicado en 2015

Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones

artículo científico publicado en 2016

Structural basis for translocation by AddAB helicase-nuclease and its arrest at χ sites

artículo científico publicado en 2014

Structure and mechanism of helicases and nucleic acid translocases

artículo científico publicado en 2007

Superfamily 1 helicases .

artículo científico

Superfamily I helicases as modular components of DNA-processing machines ⬇️

artículo científico publicado el 1 de abril de 2011

The 2B subdomain of Rep helicase links translocation along DNA with protein displacement

The AddAB helicase-nuclease catalyses rapid and processive DNA unwinding using a single Superfamily 1A motor domain

artículo científico publicado en 2010

The AddAB helicase/nuclease forms a stable complex with its cognate chi sequence during translocation.

artículo científico publicado en 2006

The conflict between DNA replication and transcription ⬇️

artículo científico publicado el 31 de mayo de 2012

The conserved C-terminus of the PcrA/UvrD helicase interacts directly with RNA polymerase

artículo científico publicado en 2013

The molecular basis of protein toxin HicA-dependent binding of the protein antitoxin HicB to DNA

artículo científico publicado en 2018

The processing of double-stranded DNA breaks for recombinational repair by helicase-nuclease complexes

artículo científico publicado en 2010

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere ⬇️

artículo científico publicado en 2017

The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase

artículo científico publicado en 2017

The unstructured C-terminal extension of UvrD interacts with UvrB, but is dispensable for nucleotide excision repair

artículo científico publicado en 2009

Translocation by the RecB motor is an absolute requirement for {chi}-recognition and RecA protein loading by RecBCD enzyme

artículo científico publicado en 2005

Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism.

artículo científico publicado en 2000

Using DNA as a fiducial marker to study SMC complex interactions with the atomic force microscope

artículo científico publicado en 2012

Visualizing helicases unwinding DNA at the single molecule level

artículo científico publicado en 2010

Lista de obras de Mark S. Dillingham

A Single-Molecule Approach to Visualize the Unwinding Activity of DNA Helicases

A dual-nuclease mechanism for DNA break processing by AddAB-type helicase-nucleases

A molecular throttle: the recombination hotspot chi controls DNA translocation by the RecBCD helicase

A new method for inferring hidden markov models from noisy time sequences

A step backward in advancing DNA replication: rescue of stalled replication forks by RecG.

AFM volumetric methods for the characterization of proteins and nucleic acids ⬇️

Alteration of χ recognition by RecBCD reveals a regulated molecular latch and suggests a channel-bypass mechanism for biological control

An iron-sulfur cluster is essential for the binding of broken DNA by AddAB-type helicase-nucleases

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

Bipolar DNA translocation contributes to highly processive DNA unwinding by RecBCD enzyme

Bulk and single-molecule analysis of a bacterial DNA2-like helicase-nuclease reveals a single-stranded DNA looping motor

Chi hotspots trigger a conformational change in the helicase-like domain of AddAB to activate homologous recombination

Crystal structure of RecBCD : a machine for processing DNA breaks

Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks

Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism

CtIP forms a tetrameric dumbbell-shaped particle which bridges complex DNA end structures for double-strand break repair

DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase

Demonstration of unidirectional single-stranded DNA translocation by PcrA helicase: measurement of step size and translocation speed

Direct measurement of single-stranded DNA translocation by PcrA helicase using the fluorescent base analogue 2-aminopurine

Directional Loading and Stimulation of PcrA Helicase by the Replication Initiator Protein RepD

Engineering a reagentless biosensor for single-stranded DNA to measure real-time helicase activity in Bacillus

Escherichia coli ribosomal protein L3 stimulates the helicase activity of the Bacillus stearothermophilus PcrA helicase.

Fluorescent single-stranded DNA binding protein as a probe for sensitive, real-time assays of helicase activity

Force determination in lateral magnetic tweezers combined with TIRF microscopy.

Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus

How to Build a DNA Unwinding Machine ⬇️

Human CtIP forms a tetrameric dumbbell-shaped particle which binds and bridges complex DNA end structures for double-strand break repair

Inhibiting translation elongation can aid genome duplication in Escherichia coli

Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex

Iron–sulphur clusters in nucleic acid processing enzymes ⬇️

Molecular determinants responsible for recognition of the single-stranded DNA regulatory sequence, χ, by RecBCD enzyme

Monomeric PcrA helicase processively unwinds plasmid lengths of DNA in the presence of the initiator protein RepD.

On the mechanism of recombination hotspot scanning during double-stranded DNA break resection

ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements

ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements

Probing DNA helicase kinetics with temperature-controlled magnetic tweezers

Protein modification for single molecule fluorescence microscopy

RecBCD enzyme and the repair of double-stranded DNA breaks

RecBCD enzyme is a bipolar DNA helicase

Recombination Hotspots and Single-Stranded DNA Binding Proteins Couple DNA Translocation to DNA Unwinding by the AddAB Helicase-Nuclease

Recombination hotspots attenuate the coupled ATPase and translocase activities of an AddAB-type helicase-nuclease

Rep provides a second motor at the replisome to promote duplication of protein-bound DNA.

Repercussions of DNA tracking by the type IC restriction endonuclease EcoR124I on linear, circular and catenated substrates.

Replicative Helicases: A Staircase with a Twist

Single molecule approaches to monitor the recognition and resection of double-stranded DNA breaks during homologous recombination

Site-directed mutagenesis of motif III in PcrA helicase reveals a role in coupling ATP hydrolysis to strand separation.

Specific and non-specific interactions of ParB with DNA: implications for chromosome segregation

Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones

Structural basis for translocation by AddAB helicase-nuclease and its arrest at χ sites

Structure and mechanism of helicases and nucleic acid translocases

Superfamily 1 helicases .

Superfamily I helicases as modular components of DNA-processing machines ⬇️

The 2B subdomain of Rep helicase links translocation along DNA with protein displacement

The AddAB helicase-nuclease catalyses rapid and processive DNA unwinding using a single Superfamily 1A motor domain

The AddAB helicase/nuclease forms a stable complex with its cognate chi sequence during translocation.

The conflict between DNA replication and transcription ⬇️

The conserved C-terminus of the PcrA/UvrD helicase interacts directly with RNA polymerase

The molecular basis of protein toxin HicA-dependent binding of the protein antitoxin HicB to DNA

The processing of double-stranded DNA breaks for recombinational repair by helicase-nuclease complexes

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere ⬇️

The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase

The unstructured C-terminal extension of UvrD interacts with UvrB, but is dispensable for nucleotide excision repair

Translocation by the RecB motor is an absolute requirement for {chi}-recognition and RecA protein loading by RecBCD enzyme

Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism.

Using DNA as a fiducial marker to study SMC complex interactions with the atomic force microscope

Visualizing helicases unwinding DNA at the single molecule level