Lista de obras - Christian Ducho - Dominio Público Uruguay

A biomimetic domino reaction for the concise synthesis of capreomycidine and epicapreomycidine

artículo científico publicado en 2012

Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase.

artículo científico publicado en 2012

Amino acid motifs in natural products: synthesis of O-acylated derivatives of (2S,3S)-3-hydroxyleucine

artículo científico publicado en 2014

Aminoribosylated Analogues of Muraymycin Nucleoside Antibiotics

Analogues of Muraymycin Nucleoside Antibiotics with Epimeric Uridine-Derived Core Structures

scientific article published on 03 November 2018

Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471. ⬇️

artículo científico publicado en 2018

Aryl-substituted and benzo-annulated cyc/osal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate--correlation of structure, hydrolysis properties and anti-HIV activity

artículo científico publicado en 2002

Benzyl-functionalized cycloSal-d4T monophosphates

artículo científico publicado en 2001

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.

artículo científico publicado en 2010

Cellular Targeting of Oligonucleotides by Conjugation with Small Molecules

artículo científico publicado en 2020

Convergence leads to success: total synthesis of the complex nonribosomal peptide polytheonamide B

artículo científico publicado en 2010

Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

article

Enhanced Stability of DNA Oligonucleotides with Partially Zwitterionic Backbone Structures in Biological Media

article published in 2018

Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics

scientific article published on 24 May 2018

Enzymatically Cleavable siRNA Prodrugs: a New Paradigm for the Intracellular Delivery of RNA-Based Therapeutics

artículo científico publicado en 2015

Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics

artículo científico publicado en 2018

Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship

artículo científico publicado en 2004

Lead structures for new antibacterials: stereocontrolled synthesis of a bioactive muraymycin analogue.

artículo científico publicado en 2014

Mechanism of action of the uridyl peptide antibiotics: an unexpected link to a protein-protein interaction site in translocase MraY.

artículo científico publicado en 2014

Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit

scientific article published on 19 December 2019

NAA-modified DNA oligonucleotides with zwitterionic backbones: stereoselective synthesis of A-T phosphoramidite building blocks

artículo científico publicado en 2015

Natural Products at Work: Structural Insights into Inhibition of the Bacterial Membrane Protein MraY.

artículo científico publicado en 2016

Non-inhibition of acetylcholinesterase by cycloSal nucleotides

artículo científico publicado en 2003

Novel 5'-deoxy nucleosyl amino acid scaffolds for the synthesis of muraymycin analogues

artículo científico publicado en 2010

Novel cyclosal nucleotides with reduced inhibitory potency toward human butyrylcholinesterase

scientific article published on 01 January 2005

Oligonucleotide analogues with cationic backbone linkages.

artículo científico publicado en 2018

Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction

artículo científico publicado en 2017

Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis

artículo científico publicado en 2020

Specific, Sensitive, and Quantitative Detection of HER-2 mRNA Breast Cancer Marker by Fluorescent Light-Up Hybridization Probes

scientific article published on 31 March 2020

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases

artículo científico publicado en 2011

Stereoselective Synthesis of Uridine-Derived Nucleosyl Amino Acids

artículo científico publicado en 2011

Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor

artículo científico publicado en 2013

Synthesis and properties of DNA oligonucleotides with a zwitterionic backbone structure

artículo científico publicado en 2014

Synthesis of regio- and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis.

artículo científico publicado en 2009

The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.

artículo científico publicado en 2015

The bacterial cell envelope as delimiter of anti-infective bioavailability - An in vitro permeation model of the Gram-negative bacterial inner membrane.

artículo científico publicado en 2016

The enzymes of β-lactam biosynthesis

artículo científico publicado en 2013

Thioester Hydrolysis and CC Bond Formation by Carboxymethylproline Synthase from the Crotonase Superfamily

artículo científico publicado en 2008

Total Synthesis of Dansylated Park's Nucleotide for High-Throughput MraY Assays.

artículo científico publicado en 2016

cycloSal-d4TMP pronucleotides structural variations, mechanistic insights and antiviral activity.

artículo científico publicado en 2002

Lista de obras de Christian Ducho

A biomimetic domino reaction for the concise synthesis of capreomycidine and epicapreomycidine

Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase.

Amino acid motifs in natural products: synthesis of O-acylated derivatives of (2S,3S)-3-hydroxyleucine

Aminoribosylated Analogues of Muraymycin Nucleoside Antibiotics

Analogues of Muraymycin Nucleoside Antibiotics with Epimeric Uridine-Derived Core Structures

Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471. ⬇️

Aryl-substituted and benzo-annulated cyc/osal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate--correlation of structure, hydrolysis properties and anti-HIV activity

Benzyl-functionalized cycloSal-d4T monophosphates

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.

Cellular Targeting of Oligonucleotides by Conjugation with Small Molecules

Convergence leads to success: total synthesis of the complex nonribosomal peptide polytheonamide B

Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

Enhanced Stability of DNA Oligonucleotides with Partially Zwitterionic Backbone Structures in Biological Media

Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics

Enzymatically Cleavable siRNA Prodrugs: a New Paradigm for the Intracellular Delivery of RNA-Based Therapeutics

Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics

Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship

Lead structures for new antibacterials: stereocontrolled synthesis of a bioactive muraymycin analogue.

Mechanism of action of the uridyl peptide antibiotics: an unexpected link to a protein-protein interaction site in translocase MraY.

Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit

NAA-modified DNA oligonucleotides with zwitterionic backbones: stereoselective synthesis of A-T phosphoramidite building blocks

Natural Products at Work: Structural Insights into Inhibition of the Bacterial Membrane Protein MraY.

Non-inhibition of acetylcholinesterase by cycloSal nucleotides

Novel 5'-deoxy nucleosyl amino acid scaffolds for the synthesis of muraymycin analogues

Novel cyclosal nucleotides with reduced inhibitory potency toward human butyrylcholinesterase

Oligonucleotide analogues with cationic backbone linkages.

Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction

Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis

Specific, Sensitive, and Quantitative Detection of HER-2 mRNA Breast Cancer Marker by Fluorescent Light-Up Hybridization Probes

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases

Stereoselective Synthesis of Uridine-Derived Nucleosyl Amino Acids

Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor

Synthesis and properties of DNA oligonucleotides with a zwitterionic backbone structure

Synthesis of regio- and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis.

The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.

The bacterial cell envelope as delimiter of anti-infective bioavailability - An in vitro permeation model of the Gram-negative bacterial inner membrane.

The enzymes of β-lactam biosynthesis

Thioester Hydrolysis and CC Bond Formation by Carboxymethylproline Synthase from the Crotonase Superfamily

Total Synthesis of Dansylated Park's Nucleotide for High-Throughput MraY Assays.

cycloSal-d4TMP pronucleotides structural variations, mechanistic insights and antiviral activity.