Lista de obras - Alison E. Ashcroft - Dominio Público Uruguay

5-Methylthiopentose: a new substituent on lipoarabinomannan in Mycobacterium tuberculosis

artículo científico publicado en 2002

A comparison of the electromechanical properties of structurally diverse proteins by molecular dynamics simulation

artículo científico publicado en 2013

A comparison of the folding characteristics of free and ribosome-tethered polypeptide chains using limited proteolysis and mass spectrometry ⬇️

artículo científico publicado en 2015

A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3. ⬇️

artículo científico publicado en 2013

Amphipathic polymers enable the study of functional membrane proteins in the gas phase ⬇️

artículo científico publicado en 2012

Amphipols outperform dodecylmaltoside micelles in stabilizing membrane protein structure in the gas phase ⬇️

artículo científico publicado en 2014

An in vivo platform for identifying inhibitors of protein aggregation ⬇️

artículo científico publicado en 2015

An in vivo platform to select and evolve aggregation-resistant proteins

scientific article published on 14 April 2020

Analysis of amyloid nanostructures using photo-cross-linking: in situ comparison of three widely used photo-cross-linkers ⬇️

artículo científico

Assembly Pathway of Hepatitis B Core Virus-like Particles from Genetically Fused Dimers ⬇️

artículo científico publicado en 2015

Capillary filling of miniaturized sources for electrospray mass spectrometry

Changes in protein structure monitored by use of gas-phase hydrogen/deuterium exchange

artículo científico publicado en 2015

Characterization of Amyloid Oligomers by Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry (ESI-IMS-MS).

artículo científico publicado en 2016

Co-populated conformational ensembles of beta2-microglobulin uncovered quantitatively by electrospray ionization mass spectrometry ⬇️

artículo científico publicado en 2004

Conformational flexibility within the nascent polypeptide-associated complex enables its interactions with structurally diverse client proteins. ⬇️

artículo científico publicado en 2018

Considerations in experimental and theoretical collision cross-section measurements of small molecules using travelling wave ion mobility spectrometry-mass spectrometry

article

Control of domain swapping in bovine odorant-binding protein

artículo científico publicado en 2002

Covalent cross-linking within supramolecular peptide structures.

artículo científico publicado en 2012

Critical concentrations of beta-sheet peptide self-assembly quantified directly by nanoelectrospray ionization mass spectrometry

artículo científico publicado en 2008

Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation

artículo científico publicado en 2013

De novo sequencing of short interfering ribonucleic acids facilitated by use of tandem mass spectrometry with ion mobility spectrometry

artículo científico publicado en 2013

Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies

artículo científico publicado en 2009

Defining topological features of membrane proteins by nanoelectrospray ionisation mass spectrometry

artículo científico publicado en 2010

Determining the topology of virus assembly intermediates using ion mobility spectrometry-mass spectrometry

artículo científico publicado en 2010

Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry.

artículo científico publicado en 2006

Does either the gastrointestinal peptide PYY or the neuropeptide NPY bind aluminium?

artículo científico publicado en 2003

Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism

artículo científico publicado en 2006

Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics ⬇️

artículo científico publicado en 2007

ESI-IMS-MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules ⬇️

artículo científico publicado en 2015

Effect of sequence variation on the mechanical response of amyloid fibrils probed by steered molecular dynamics simulation

artículo científico publicado en 2012

Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding ⬇️

artículo científico publicado en 2017

Elongated oligomers in beta2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry

artículo científico publicado en 2010

Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo ⬇️

artículo científico publicado en 2016

Engineering thermal stability in RNA phage capsids via disulphide bonds

artículo científico publicado en 2005

Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion ⬇️

artículo científico publicado en 2015

Expanding the repertoire of amyloid polymorphs by co-polymerization of related protein precursors

artículo científico publicado en 2013

FPOP-LC-MS/MS Suggests Differences in Interaction Sites of Amphipols and Detergents with Outer Membrane Proteins ⬇️

artículo científico publicado en 2016

HDX-ESI-MS reveals enhanced conformational dynamics of the amyloidogenic protein beta(2)-microglobulin upon release from the MHC-1.

artículo científico publicado en 2008

Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin ⬇️

artículo científico publicado en 2017

Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1. ⬇️

artículo científico publicado en 2017

Inducing protein aggregation by extensional flow ⬇️

artículo científico publicado en 2017

Insights into the consequences of co-polymerisation in the early stages of IAPP and Aβ peptide assembly from mass spectrometry ⬇️

artículo científico publicado en 2015

Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry ⬇️

artículo científico publicado en 2013

Insights into virus capsid assembly from non-covalent mass spectrometry

artículo científico publicado en 2008

Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients

artículo científico publicado en 2020

Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS. ⬇️

artículo científico publicado en 2017

Investigating the structural properties of amyloid-like fibrils formed in vitro from beta2-microglobulin using limited proteolysis and electrospray ionisation mass spectrometry.

artículo científico publicado en 2006

Ion mobility spectrometry-mass spectrometry defines the oligomeric intermediates in amylin amyloid formation and the mode of action of inhibitors ⬇️

artículo científico publicado en 2013

Large-scale production and structural and biophysical characterizations of the human hepatitis B virus polymerase

artículo científico publicado en 2013

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM. ⬇️

artículo científico publicado en 2016

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein ⬇️

artículo científico

Long-Range Conformational Changes in Monoclonal Antibodies Revealed Using FPOP-LC-MS/MS

scientific article published on 13 November 2019

Mass spectrometric methods to analyze the structural organization of macromolecular complexes

artículo científico

Mass spectrometry and the amyloid problem--how far can we go in the gas phase?

artículo científico publicado en 2010

Mechanisms of parasite-induced sex reversal in Gammarus duebeni

artículo científico publicado en 2004

Metals accelerate the formation and direct the structure of amyloid fibrils of NAC.

artículo científico publicado en 2005

Molecular dissection of membrane-transport proteins: mass spectrometry and sequence determination of the galactose-H+ symport protein, GalP, of Escherichia coli and quantitative assay of the incorporation of [ring-2-13C]histidine and (15)NH(3).

artículo científico publicado en 2002

Molecular dynamics simulations of mechanical failure in polymorphic arrangements of amyloid fibrils containing structural defects ⬇️

artículo científico publicado en 2013

Monitoring copopulated conformational states during protein folding events using electrospray ionization-ion mobility spectrometry-mass spectrometry

artículo científico publicado en 2007

Monitoring oligomer formation from self-aggregating amylin peptides using ESI-IMS-MS

Mutational analysis of the ability of resveratrol to inhibit amyloid formation by islet amyloid polypeptide: critical evaluation of the importance of aromatic-inhibitor and histidine-inhibitor interactions

artículo científico publicado en 2015

N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

artículo científico publicado en 2012

Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization ⬇️

artículo científico publicado en 2013

On the quaternary association of the type III secretion system HrcQB-C protein: experimental evidence differentiates among the various oligomerization models

artículo científico publicado en 2009

Probing bunyavirus N protein oligomerisation using mass spectrometry

artículo científico publicado en 2014

Protein and peptide identification: the rôle of mass spectrometry in proteomics ⬇️

artículo científico publicado el 1 de abril de 2003

Protein destabilisation by ruthenium(II) tris-bipyridine based protein-surface mimetics

artículo científico publicado en 2013

Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives

artículo científico publicado en 2010

RNA Packing Specificity and Folding during Assembly of the Bacteriophage MS2

scholarly article by Ottar Rolfsson et al published 2008 in Computational and Mathematical Methods in Medicine

RNA-induced conformational changes in a viral coat protein studied by hydrogen/deuterium exchange mass spectrometry

artículo científico publicado en 2010

Real-time measurement of myosin-nucleotide noncovalent complexes by electrospray ionization mass spectrometry

artículo científico publicado en 2007

Recent developments in electrospray ionisation mass spectrometry: noncovalently bound protein complexes

artículo científico publicado en 2005

Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein

artículo científico publicado en 2009

Scanning conformational space with a library of stereo- and regiochemically diverse aminoglycoside derivatives: the discovery of new ligands for RNA hairpin sequences

artículo científico publicado en 2007

Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry-mass spectrometry ⬇️

artículo científico publicado en 2014

Second order rate constants of donor-strand exchange reveal individual amino acid residues important in determining the subunit specificity of pilus biogenesis ⬇️

artículo científico publicado en 2011

Selective protein-surface sensing using ruthenium(II) tris(bipyridine) complexes

artículo científico publicado en 2010

Separation of beta2-microglobulin conformers by high-field asymmetric waveform ion mobility spectrometry (FAIMS) coupled to electrospray ionisation mass spectrometry.

artículo científico publicado en 2004

Skp is a multivalent chaperone of outer-membrane proteins ⬇️

artículo científico publicado en 2016

Small molecule probes of protein aggregation ⬇️

artículo científico publicado en 2017

Structural analysis of Bacillus subtilis SPP1 phage helicase loader protein G39P

artículo científico publicado en 2003

Structural determinants of polymerization reactivity of the P pilus adaptor subunit PapF

artículo científico publicado en 2008

Structural plasticity and noncovalent substrate binding in the GroEL apical domain. A study using electrospay ionization mass spectrometry and fluorescence binding studies ⬇️

artículo científico publicado en 2002

Structure and dynamics of oligomeric intermediates in β2-microglobulin self-assembly

artículo científico

Synthesis, characterization and applications of a perdeuterated amphipol

artículo científico publicado en 2014

Systematic analysis of the use of amphipathic polymers for studies of outer membrane proteins using mass spectrometry ⬇️

artículo científico publicado en 2015

The effect of dimethylbiguanide on thrombin activity, FXIII activation, fibrin polymerization, and fibrin clot formation

artículo científico publicado en 2002

The feeding tube of cyst nematodes: characterisation of protein exclusion ⬇️

artículo científico publicado en 2014

The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry

artículo científico publicado en 2013

The impact of viral RNA on assembly pathway selection.

artículo científico publicado en 2010

The opening of the SPP1 bacteriophage tail, a prevalent mechanism in Gram-positive-infecting siphophages

artículo científico publicado en 2011

The role of chaperone-subunit usher domain interactions in the mechanism of bacterial pilus biogenesis revealed by ESI-MS.

artículo científico publicado en 2012

The role of conformational flexibility in β2-microglobulin amyloid fibril formation at neutral pH. ⬇️

artículo científico publicado en 2012

The role of ion mobility spectrometry-mass spectrometry in the analysis of protein reference standards

artículo científico publicado en 2013

The use of electrospray mass spectrometry to determine speciation in a dynamic combinatorial library for anion recognition ⬇️

artículo científico publicado en 2012

Thermodynamic origins of protein folding, allostery, and capsid formation in the human hepatitis B virus core protein

artículo científico publicado en 2013

Topological Dissection of the Membrane Transport Protein Mhp1 Derived from Cysteine Accessibility and Mass Spectrometry ⬇️

artículo científico publicado en 2017

Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation

artículo científico publicado en 2008

Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers ⬇️

artículo científico publicado en 2017

Understanding quinone cofactor biogenesis in methylamine dehydrogenase through novel cofactor generation

artículo científico publicado en 2003

Unraveling lactococcal phage baseplate assembly by mass spectrometry

artículo científico

Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry ⬇️

artículo científico publicado en 2008

Using hydroxyl radical footprinting to explore the free energy landscape of protein folding. ⬇️

artículo científico publicado en 2015

Using ion mobility spectrometry-mass spectrometry to decipher the conformational and assembly characteristics of the hepatitis B capsid protein ⬇️

artículo científico publicado en 2013

Viral genomic single-stranded RNA directs the pathway toward a T=3 capsid

artículo científico publicado en 2009

Widespread, routine occurrence of pharmaceuticals in sewage effluent, combined sewer overflows and receiving waters ⬇️

artículo científico publicado en 2016

Lista de obras de Alison E. Ashcroft

5-Methylthiopentose: a new substituent on lipoarabinomannan in Mycobacterium tuberculosis

A comparison of the electromechanical properties of structurally diverse proteins by molecular dynamics simulation

A comparison of the folding characteristics of free and ribosome-tethered polypeptide chains using limited proteolysis and mass spectrometry ⬇️

A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3. ⬇️

Amphipathic polymers enable the study of functional membrane proteins in the gas phase ⬇️

Amphipols outperform dodecylmaltoside micelles in stabilizing membrane protein structure in the gas phase ⬇️

An in vivo platform for identifying inhibitors of protein aggregation ⬇️

An in vivo platform to select and evolve aggregation-resistant proteins

Analysis of amyloid nanostructures using photo-cross-linking: in situ comparison of three widely used photo-cross-linkers ⬇️

Assembly Pathway of Hepatitis B Core Virus-like Particles from Genetically Fused Dimers ⬇️

Capillary filling of miniaturized sources for electrospray mass spectrometry

Changes in protein structure monitored by use of gas-phase hydrogen/deuterium exchange

Characterization of Amyloid Oligomers by Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry (ESI-IMS-MS).

Co-populated conformational ensembles of beta2-microglobulin uncovered quantitatively by electrospray ionization mass spectrometry ⬇️

Conformational flexibility within the nascent polypeptide-associated complex enables its interactions with structurally diverse client proteins. ⬇️

Considerations in experimental and theoretical collision cross-section measurements of small molecules using travelling wave ion mobility spectrometry-mass spectrometry

Control of domain swapping in bovine odorant-binding protein

Covalent cross-linking within supramolecular peptide structures.

Critical concentrations of beta-sheet peptide self-assembly quantified directly by nanoelectrospray ionization mass spectrometry

Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation

De novo sequencing of short interfering ribonucleic acids facilitated by use of tandem mass spectrometry with ion mobility spectrometry

Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies

Defining topological features of membrane proteins by nanoelectrospray ionisation mass spectrometry

Determining the topology of virus assembly intermediates using ion mobility spectrometry-mass spectrometry

Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry.

Does either the gastrointestinal peptide PYY or the neuropeptide NPY bind aluminium?

Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism

Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics ⬇️

ESI-IMS-MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules ⬇️

Effect of sequence variation on the mechanical response of amyloid fibrils probed by steered molecular dynamics simulation

Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding ⬇️

Elongated oligomers in beta2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry

Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo ⬇️

Engineering thermal stability in RNA phage capsids via disulphide bonds

Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion ⬇️

Expanding the repertoire of amyloid polymorphs by co-polymerization of related protein precursors

FPOP-LC-MS/MS Suggests Differences in Interaction Sites of Amphipols and Detergents with Outer Membrane Proteins ⬇️

HDX-ESI-MS reveals enhanced conformational dynamics of the amyloidogenic protein beta(2)-microglobulin upon release from the MHC-1.

Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin ⬇️

Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1. ⬇️

Inducing protein aggregation by extensional flow ⬇️

Insights into the consequences of co-polymerisation in the early stages of IAPP and Aβ peptide assembly from mass spectrometry ⬇️

Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry ⬇️

Insights into virus capsid assembly from non-covalent mass spectrometry

Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients

Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS. ⬇️

Investigating the structural properties of amyloid-like fibrils formed in vitro from beta2-microglobulin using limited proteolysis and electrospray ionisation mass spectrometry.

Ion mobility spectrometry-mass spectrometry defines the oligomeric intermediates in amylin amyloid formation and the mode of action of inhibitors ⬇️

Large-scale production and structural and biophysical characterizations of the human hepatitis B virus polymerase

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM. ⬇️

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein ⬇️

Long-Range Conformational Changes in Monoclonal Antibodies Revealed Using FPOP-LC-MS/MS

Mass spectrometric methods to analyze the structural organization of macromolecular complexes

Mass spectrometry and the amyloid problem--how far can we go in the gas phase?

Mechanisms of parasite-induced sex reversal in Gammarus duebeni

Metals accelerate the formation and direct the structure of amyloid fibrils of NAC.

Molecular dissection of membrane-transport proteins: mass spectrometry and sequence determination of the galactose-H+ symport protein, GalP, of Escherichia coli and quantitative assay of the incorporation of [ring-2-13C]histidine and (15)NH(3).

Molecular dynamics simulations of mechanical failure in polymorphic arrangements of amyloid fibrils containing structural defects ⬇️

Monitoring copopulated conformational states during protein folding events using electrospray ionization-ion mobility spectrometry-mass spectrometry

Monitoring oligomer formation from self-aggregating amylin peptides using ESI-IMS-MS

Mutational analysis of the ability of resveratrol to inhibit amyloid formation by islet amyloid polypeptide: critical evaluation of the importance of aromatic-inhibitor and histidine-inhibitor interactions

N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization ⬇️

On the quaternary association of the type III secretion system HrcQB-C protein: experimental evidence differentiates among the various oligomerization models

Probing bunyavirus N protein oligomerisation using mass spectrometry

Protein and peptide identification: the rôle of mass spectrometry in proteomics ⬇️

Protein destabilisation by ruthenium(II) tris-bipyridine based protein-surface mimetics

Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives

RNA Packing Specificity and Folding during Assembly of the Bacteriophage MS2

RNA-induced conformational changes in a viral coat protein studied by hydrogen/deuterium exchange mass spectrometry

Real-time measurement of myosin-nucleotide noncovalent complexes by electrospray ionization mass spectrometry

Recent developments in electrospray ionisation mass spectrometry: noncovalently bound protein complexes

Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein

Scanning conformational space with a library of stereo- and regiochemically diverse aminoglycoside derivatives: the discovery of new ligands for RNA hairpin sequences

Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry-mass spectrometry ⬇️

Second order rate constants of donor-strand exchange reveal individual amino acid residues important in determining the subunit specificity of pilus biogenesis ⬇️

Selective protein-surface sensing using ruthenium(II) tris(bipyridine) complexes

Separation of beta2-microglobulin conformers by high-field asymmetric waveform ion mobility spectrometry (FAIMS) coupled to electrospray ionisation mass spectrometry.

Skp is a multivalent chaperone of outer-membrane proteins ⬇️