Lista de obras - Denis Furling - Dominio Público Uruguay

A defective Krab-domain zinc-finger transcription factor contributes to altered myogenesis in myotonic dystrophy type 1

artículo científico publicado en 2013

Abnormal prostaglandin E2 production blocks myogenic differentiation in myotonic dystrophy

artículo científico publicado en 2011

Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy

artículo científico publicado en 2015

Activation of the interferon type I response rather than autophagy contributes to myogenesis inhibition in congenital DM1 myoblasts

artículo científico publicado en 2018

Altered signal transduction pathways and induction of autophagy in human myotonic dystrophy type 1 myoblasts

artículo científico publicado en 2010

Analysis of exonic regions involved in nuclear localization, splicing activity, and dimerization of Muscleblind-like-1 isoforms

artículo científico publicado en 2011

Association Between Mutation Size and Cardiac Involvement in Myotonic Dystrophy Type 1: An Analysis of the DM1-Heart Registry

artículo científico

CRISPR/Cas9-Induced (CTG⋅CAG)n Repeat Instability in the Myotonic Dystrophy Type 1 Locus: Implications for Therapeutic Genome Editing.

artículo científico publicado en 2017

Cells of Matter-In Vitro Models for Myotonic Dystrophy.

artículo científico publicado en 2018

Changes in myotonic dystrophy protein kinase levels and muscle development in congenital myotonic dystrophy

artículo científico publicado en 2003

Decreased levels of myotonic dystrophy protein kinase (DMPK) and delayed differentiation in human myotonic dystrophy myoblasts

scientific article published on 01 November 2001

Defective mRNA in myotonic dystrophy accumulates at the periphery of nuclear splicing speckles

artículo científico publicado en 2007

Defective satellite cells in congenital myotonic dystrophy

artículo científico publicado en 2001

Development and Validation of a New Scoring System to Predict Survival in Patients With Myotonic Dystrophy Type 1.

artículo científico publicado en 2018

Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy.

artículo científico publicado en 2017

Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle

artículo científico publicado en 2016

Effect of constitutive inactivation of the myostatin gene on the gain in muscle strength during postnatal growth in two murine models

artículo científico publicado en 2016

Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells

artículo científico publicado en 2018

Endogenous TWIST expression and differentiation are opposite during human muscle development

artículo científico publicado en 2011

Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle.

artículo científico publicado en 2011

Extended Amplification In Vitro and Replicative Senescence: Key Factors Implicated in the Success of Human Myoblast Transplantation

artículo científico publicado en 2003

Gain of RNA function in pathological cases: Focus on myotonic dystrophy.

artículo científico publicado en 2011

High Risk of Fatal and Nonfatal Venous Thromboembolism in Myotonic Dystrophy

artículo científico publicado en 2018

High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines

artículo científico publicado en 2013

Human circulating AC133+ stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle

IGF-1 induces human myotube hypertrophy by increasing cell recruitment

scientific article published on 01 September 2004

IL-13 mediates the recruitment of reserve cells for fusion during IGF-1-induced hypertrophy of human myotubes

artículo científico publicado en 2007

Immortalized Skin Fibroblasts Expressing Conditional MyoD as a Renewable and Reliable Source of Converted Human Muscle Cells to Assess Therapeutic Strategies for Muscular Dystrophies: Validation of an Exon-Skipping Approach to Restore Dystrophin in D

scholarly article by Soraya Chaouch published in July 2009

Immortalized human myotonic dystrophy muscle cell lines to assess therapeutic compounds.

artículo científico publicado en 2017

Immunocytochemical localization of seleno-glutathione peroxidase in the adult mouse brain

artículo científico publicado en 1996

Impairment of synaptic transmission by transient hypoxia in hippocampal slices: improved recovery in glutathione peroxidase transgenic mice

artículo científico publicado en 2000

Improvement of Dystrophic Muscle Fragility by Short-Term Voluntary Exercise through Activation of Calcineurin Pathway in mdx Mice

artículo científico publicado en 2018

In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin

artículo científico publicado en 2015

In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts

article

L'IGF-1 induit une augmentation de la taille et du contenu en myosine des myotubes humains

Large CTG repeats trigger p16-dependent premature senescence in myotonic dystrophy type 1 muscle precursor cells

scientific article published on 26 February 2009

Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins

artículo científico publicado en 2016

Mechanical Overloading Increases Maximal Force and Reduces Fragility in Hind Limb Skeletal Muscle from Mdx Mouse

artículo científico publicado en 2015

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

artículo científico publicado en 2011

Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy

artículo científico publicado en 2011

Molecular, physiological, and motor performance defects in DMSXL mice carrying >1,000 CTG repeats from the human DM1 locus

artículo científico publicado en 2012

Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle

artículo científico publicado en 2008

MyoD transcription factor induces myogenesis by inhibiting Twist-1 through miR-206

scientific article published on 13 August 2015

Myocytes from congenital myotonic dystrophy display abnormal Na+ channel activities

article

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

artículo científico publicado en 2010

New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats

artículo científico publicado en 2011

Nuclear protein spreading: implication for pathophysiology of neuromuscular diseases.

artículo científico publicado en 2014

Pluripotent Stem Cell-Based Drug Screening Reveals Cardiac Glycosides as Modulators of Myotonic Dystrophy Type 1

artículo científico publicado en 2018

Potassium currents in human myogenic cells from healthy and congenital myotonic dystrophy foetuses

artículo científico publicado en 2009

Precise small-molecule recognition of a toxic CUG RNA repeat expansion.

artículo científico publicado en 2016

Progressive skeletal muscle weakness in transgenic mice expressing CTG expansions is associated with the activation of the ubiquitin–proteasome pathway

artículo científico publicado en 2010

RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1

artículo científico publicado en 2014

Replicative aging down-regulates the myogenic regulatory factors in human myoblasts.

artículo científico publicado en 2008

Satellite cell dysfunction contributes to the progressive muscle atrophy in myotonic dystrophy type 1.

artículo científico publicado en 2009

Selective silencing of mutated mRNAs in DM1 by using modified hU7-snRNAs

artículo científico publicado en 2010

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

artículo científico publicado en 2016

Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation

artículo científico publicado en 2011

Targeting deregulated AMPK/mTORC1 pathways improves muscle function in myotonic dystrophy type I.

scientific article published on 09 January 2017

Therapeutic Approaches for Dominant Muscle Diseases: Highlight on Myotonic Dystrophy

artículo científico publicado en 2015

Transplantation of Human Myoblasts in SCID Mice as a Potential Muscular Model for Myotonic Dystrophy

article

Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy.

artículo científico publicado en 2009

Viral vector producing antisense RNA restores myotonic dystrophy myoblast functions

artículo científico publicado en 2003

rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences.

artículo científico publicado en 2018

Lista de obras de Denis Furling

A defective Krab-domain zinc-finger transcription factor contributes to altered myogenesis in myotonic dystrophy type 1

Abnormal prostaglandin E2 production blocks myogenic differentiation in myotonic dystrophy

Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy

Activation of the interferon type I response rather than autophagy contributes to myogenesis inhibition in congenital DM1 myoblasts

Altered signal transduction pathways and induction of autophagy in human myotonic dystrophy type 1 myoblasts

Analysis of exonic regions involved in nuclear localization, splicing activity, and dimerization of Muscleblind-like-1 isoforms

Association Between Mutation Size and Cardiac Involvement in Myotonic Dystrophy Type 1: An Analysis of the DM1-Heart Registry

CRISPR/Cas9-Induced (CTG⋅CAG)n Repeat Instability in the Myotonic Dystrophy Type 1 Locus: Implications for Therapeutic Genome Editing.

Cells of Matter-In Vitro Models for Myotonic Dystrophy.

Changes in myotonic dystrophy protein kinase levels and muscle development in congenital myotonic dystrophy

Decreased levels of myotonic dystrophy protein kinase (DMPK) and delayed differentiation in human myotonic dystrophy myoblasts

Defective mRNA in myotonic dystrophy accumulates at the periphery of nuclear splicing speckles

Defective satellite cells in congenital myotonic dystrophy

Development and Validation of a New Scoring System to Predict Survival in Patients With Myotonic Dystrophy Type 1.

Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy.

Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle

Effect of constitutive inactivation of the myostatin gene on the gain in muscle strength during postnatal growth in two murine models

Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells

Endogenous TWIST expression and differentiation are opposite during human muscle development

Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle.

Extended Amplification In Vitro and Replicative Senescence: Key Factors Implicated in the Success of Human Myoblast Transplantation

Gain of RNA function in pathological cases: Focus on myotonic dystrophy.

High Risk of Fatal and Nonfatal Venous Thromboembolism in Myotonic Dystrophy

High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines

Human circulating AC133+ stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle

IGF-1 induces human myotube hypertrophy by increasing cell recruitment

IL-13 mediates the recruitment of reserve cells for fusion during IGF-1-induced hypertrophy of human myotubes

Immortalized Skin Fibroblasts Expressing Conditional MyoD as a Renewable and Reliable Source of Converted Human Muscle Cells to Assess Therapeutic Strategies for Muscular Dystrophies: Validation of an Exon-Skipping Approach to Restore Dystrophin in D

Immortalized human myotonic dystrophy muscle cell lines to assess therapeutic compounds.

Immunocytochemical localization of seleno-glutathione peroxidase in the adult mouse brain

Impairment of synaptic transmission by transient hypoxia in hippocampal slices: improved recovery in glutathione peroxidase transgenic mice

Improvement of Dystrophic Muscle Fragility by Short-Term Voluntary Exercise through Activation of Calcineurin Pathway in mdx Mice

In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin

In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts

L'IGF-1 induit une augmentation de la taille et du contenu en myosine des myotubes humains

Large CTG repeats trigger p16-dependent premature senescence in myotonic dystrophy type 1 muscle precursor cells

Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins

Mechanical Overloading Increases Maximal Force and Reduces Fragility in Hind Limb Skeletal Muscle from Mdx Mouse

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy

Molecular, physiological, and motor performance defects in DMSXL mice carrying >1,000 CTG repeats from the human DM1 locus

Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle

MyoD transcription factor induces myogenesis by inhibiting Twist-1 through miR-206

Myocytes from congenital myotonic dystrophy display abnormal Na+ channel activities

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats

Nuclear protein spreading: implication for pathophysiology of neuromuscular diseases.

Pluripotent Stem Cell-Based Drug Screening Reveals Cardiac Glycosides as Modulators of Myotonic Dystrophy Type 1

Potassium currents in human myogenic cells from healthy and congenital myotonic dystrophy foetuses

Precise small-molecule recognition of a toxic CUG RNA repeat expansion.

Progressive skeletal muscle weakness in transgenic mice expressing CTG expansions is associated with the activation of the ubiquitin–proteasome pathway

RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1

Replicative aging down-regulates the myogenic regulatory factors in human myoblasts.

Satellite cell dysfunction contributes to the progressive muscle atrophy in myotonic dystrophy type 1.

Selective silencing of mutated mRNAs in DM1 by using modified hU7-snRNAs

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation

Targeting deregulated AMPK/mTORC1 pathways improves muscle function in myotonic dystrophy type I.

Therapeutic Approaches for Dominant Muscle Diseases: Highlight on Myotonic Dystrophy

Transplantation of Human Myoblasts in SCID Mice as a Potential Muscular Model for Myotonic Dystrophy

Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy.

Viral vector producing antisense RNA restores myotonic dystrophy myoblast functions

rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences.