Lista de obras - Nacho Aguilo - Dominio Público Uruguay

A human dendritic cell-based in vitro model to assess Mycobacterium tuberculosis SO2 vaccine immunogenicity

artículo científico publicado en 2014

A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component

artículo científico publicado en 2014

Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance.

artículo científico publicado en 2018

Attenuated Mycobacterium tuberculosis SO2 vaccine candidate is unable to induce cell death.

artículo científico publicado en 2012

Autoimmune lymphoproliferative syndrome (ALPS) in a patient with a new germline Fas gene mutation

article

Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis.

artículo científico publicado en 2014

Breaking Transmission with Vaccines: The Case of Tuberculosis.

artículo científico publicado en 2017

Cell cycle regulation by FasL and Apo2L/TRAIL in human T-cell blasts. Implications for autoimmune lymphoproliferative syndromes

artículo científico publicado en 2008

Cytotoxicity of quinone drugs on highly proliferative human leukemia T cells: Reactive oxygen species generation and inactive shortened SOD1 isoform implications ⬇️

artículo científico publicado el 16 de mayo de 2012

ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis.

artículo científico publicado en 2009

ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question

artículo científico publicado en 2013

ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis

artículo científico publicado en 2013

Elucidating sources and roles of granzymes A and B during bacterial infection and sepsis

artículo científico publicado en 2014

Evaluation of the Mycobacterium tuberculosis SO2 vaccine using a natural tuberculosis infection model in goats.

artículo científico publicado en 2017

Evaluation of the immunogenicity and diagnostic interference caused by M. tuberculosis SO2 vaccination against tuberculosis in goats

artículo científico publicado en 2015

Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

artículo científico publicado en 2016

Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation.

artículo científico publicado en 2010

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

artículo científico publicado en 2015

Hyper-attenuated MTBVAC erp mutant protects against tuberculosis in mice

artículo científico publicado en 2014

IFNα signaling through PKC-θ is essential for antitumor NK cell function

artículo científico publicado en 2014

IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenuated BPZE1 vaccine

artículo científico publicado en 2018

Impaired anti-leukemic immune response in PKCtheta-deficient mice

artículo científico publicado en 2008

Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference

artículo científico publicado en 2020

Klebsiella pneumoniae survives within macrophages by avoiding delivery to lysosomes

artículo científico publicado en 2015

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

artículo científico publicado en 2015

MTBVAC from discovery to clinical trials in tuberculosis-endemic countries

artículo científico publicado en 2017

MTBVAC vaccine is safe, immunogenic and confers protective efficacy against Mycobacterium tuberculosis in newborn mice

artículo científico publicado en 2015

MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against in Mice

article

MTBVAC: Attenuating the Human Pathogen of Tuberculosis (TB) Toward a Promising Vaccine against the TB Epidemic.

artículo científico publicado en 2017

Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu,Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis

scientific journal article

Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion

artículo científico publicado en 2015

Mycobacterium tuberculosis infection prevents asthma and abrogates eosinophilopoiesis in an experimental model

artículo científico publicado en 2019

New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages

artículo científico publicado en 2018

Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

artículo científico publicado en 2010

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

artículo científico publicado en 2016

Protective immunity afforded by attenuated, PhoP-deficient Mycobacterium tuberculosis is associated with sustained generation of CD4+ T-cell memory

artículo científico publicado en 2011

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity ⬇️

artículo científico publicado el 5 de julio de 2012

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.

artículo científico publicado en 2009

Pulmonary Mycobacterium bovis BCG vaccination confers dose-dependent superior protection compared to that of subcutaneous vaccination

artículo científico publicado en 2014

Pulmonary but Not Subcutaneous Delivery of BCG Vaccine Confers Protection to Tuberculosis-Susceptible Mice by an Interleukin 17-Dependent Mechanism.

artículo científico publicado en 2015

Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis

artículo científico publicado en 2017

Recent developments in tuberculosis vaccines

article

The induction of Bim expression in human T-cell blasts is dependent on nonapoptotic Fas/CD95 signaling

artículo científico publicado en 2006

Therapeutic efficacy of the live-attenuated Mycobacterium tuberculosis vaccine, MTBVAC, in a preclinical model of bladder cancer.

artículo científico publicado en 2018

Vacunación frente a tuberculosis

artículo científico publicado en 2018

Lista de obras de Nacho Aguilo

A human dendritic cell-based in vitro model to assess Mycobacterium tuberculosis SO2 vaccine immunogenicity

A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component

Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance.

Attenuated Mycobacterium tuberculosis SO2 vaccine candidate is unable to induce cell death.

Autoimmune lymphoproliferative syndrome (ALPS) in a patient with a new germline Fas gene mutation

Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis.

Breaking Transmission with Vaccines: The Case of Tuberculosis.

Cell cycle regulation by FasL and Apo2L/TRAIL in human T-cell blasts. Implications for autoimmune lymphoproliferative syndromes

Cytotoxicity of quinone drugs on highly proliferative human leukemia T cells: Reactive oxygen species generation and inactive shortened SOD1 isoform implications ⬇️

ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis.

ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question

ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis

Elucidating sources and roles of granzymes A and B during bacterial infection and sepsis

Evaluation of the Mycobacterium tuberculosis SO2 vaccine using a natural tuberculosis infection model in goats.

Evaluation of the immunogenicity and diagnostic interference caused by M. tuberculosis SO2 vaccination against tuberculosis in goats

Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation.

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

Hyper-attenuated MTBVAC erp mutant protects against tuberculosis in mice

IFNα signaling through PKC-θ is essential for antitumor NK cell function

IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenuated BPZE1 vaccine

Impaired anti-leukemic immune response in PKCtheta-deficient mice

Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference

Klebsiella pneumoniae survives within macrophages by avoiding delivery to lysosomes

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

MTBVAC from discovery to clinical trials in tuberculosis-endemic countries

MTBVAC vaccine is safe, immunogenic and confers protective efficacy against Mycobacterium tuberculosis in newborn mice

MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against in Mice

MTBVAC: Attenuating the Human Pathogen of Tuberculosis (TB) Toward a Promising Vaccine against the TB Epidemic.

Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu,Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis

Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion

Mycobacterium tuberculosis infection prevents asthma and abrogates eosinophilopoiesis in an experimental model

New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages

Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Protective immunity afforded by attenuated, PhoP-deficient Mycobacterium tuberculosis is associated with sustained generation of CD4+ T-cell memory

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity ⬇️

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.

Pulmonary Mycobacterium bovis BCG vaccination confers dose-dependent superior protection compared to that of subcutaneous vaccination

Pulmonary but Not Subcutaneous Delivery of BCG Vaccine Confers Protection to Tuberculosis-Susceptible Mice by an Interleukin 17-Dependent Mechanism.

Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis

Recent developments in tuberculosis vaccines

The induction of Bim expression in human T-cell blasts is dependent on nonapoptotic Fas/CD95 signaling

Therapeutic efficacy of the live-attenuated Mycobacterium tuberculosis vaccine, MTBVAC, in a preclinical model of bladder cancer.

Vacunación frente a tuberculosis