Lista de obras - Mattie Timmer - Dominio Público Uruguay

A divergent approach to the synthesis of iGb3 sugar and lipid analogues via a lactosyl 2-azido-sphingosine intermediate

scientific article published on 01 May 2014

A fast, efficient and stereoselective synthesis of hydroxy-pyrrolidines.

artículo científico publicado en 2010

A practical synthesis of gramicidin s and sugar amino Acid containing analogues.

artículo científico publicado en 2004

A short route toward chiral, polyhydroxylated indolizidines and quinolizidines

artículo científico publicado en 2003

Activation of type II NADH dehydrogenase by quinolinequinones mediates antitubercular cell death

artículo científico publicado en 2016

Agonistic or antagonistic mucosal-associated invariant T (MAIT) cell activity is determined by the 6-alkylamino substituent on uracil MR1 ligands

scientific article published on 09 April 2020

Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties

artículo científico publicado en 2016

An Expedient Synthesis of the Repeating Unit of the Acidic Polysaccharide of the Bacteriolytic Complex of Lysoamidase

artículo científico publicado en 2005

An efficient synthesis of a 6″-BODIPY-α-Galactosylceramide probe for monitoring α-Galactosylceramide uptake by cells

artículo científico publicado en 2019

An expeditious route to phosphorus heterocycles based on ring-closing metathesis

An improved synthesis of dansylated α-galactosylceramide and its use as a fluorescent probe for the monitoring of glycolipid uptake by cells

artículo científico publicado en 2011

An unusual reverse turn structure adopted by a furanoid sugar amino acid incorporated in gramicidin S.

artículo científico publicado en 2004

Applications and limitations of the I2-mediated carbamate annulation for the synthesis of piperidines: five- versus six-membered ring formation

artículo científico publicado en 2013

Az—a colourful azulene-derived protecting group

Bi-analyte SERS with isotopically edited dyes

scientific article published on 03 June 2008

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

artículo científico publicado en 2016

Carbohydrates as Versatile Platforms in the Construction of Small Compound Libraries

Carbohydrates as versatile platforms in the construction of small compound libraries

ChemInform Abstract: An Expeditious Route to Phosphorus Heterocycles Based on Ring-Closing Metathesis

ChemInform Abstract: Applications and Limitations of the I2-Mediated Carbamate Annulation for the Synthesis of Piperidines: Five- versus Six-Membered Ring Formation

ChemInform Abstract: Az - A Colorful Azulene-Derived Protecting Group

ChemInform Abstract: Chemical Tools for Studying the Biological Function of Glycolipids

ChemInform Abstract: I2-Mediated Carbamate Annulation: Scope and Application in the Synthesis of Aza-Sugars

ChemInform Abstract: Protecting-Group-Free Synthesis of Amines: Synthesis of Primary Amines from Aldehydes via Reductive Amination

ChemInform Abstract: Recent Developments in the Synthesis of Pyrrolidine-Containing Iminosugars

ChemInform Abstract: Stereocontrolled Synthesis of Fully Functionalized D-Glucosamine Monosaccharides via a Domino Nitro-Michael/Henry Reaction

ChemInform Abstract: Synthesis of Phosphorus Mono- and Bicycles by Catalytic Ring-Closing Metathesis

ChemInform Abstract: The Synthesis of Long-Chain α-Alkyl-β-hydroxy Esters Using Allylic Halides in a Frater-Seebach Alkylation

ChemInform Abstract: Total Synthesis of Aigialomycin D Using a Ramberg-Baecklund/RCM Strategy

ChemInform Abstract: Trehalose Glycolipids - Synthesis and Biological Activities

Chemical tools for studying the biological function of glycolipids

artículo científico

Claisen self-condensation/decarboxylation as the key steps in the synthesis of C2-symmetrical 1,7-dioxaspiro[5.5]undecanes

Cover Picture: Long-Chain Lipids Are Required for the Innate Immune Recognition of Trehalose Diesters by Macrophages (ChemBioChem 17/2011)

scientific article published in 2011

De Novo Synthesis of Aceric Acid and an Aceric Acid Building Block

scientific article published on 01 October 2006

De Novo Synthesis of Uronic Acid Building Blocks for Assembly of Heparin Oligosaccharides

artículo científico publicado en 2007

De-novo-Synthese von vollständig funktionalisierten Uronsäure-Monosacchariden

Development of a benzophenone and alkyne functionalised trehalose probe to study trehalose dimycolate binding proteins

artículo científico publicado en 2012

Diastereoselective Carbamate Annulation for the Synthesis of 2,5-Dideoxy-2,5-iminoglycitols

Discovery of lipids from B. longum subsp. infantis using whole cell MALDI analysis

artículo científico publicado en 2014

Endogenous and Exogenous CD1-Binding Glycolipids

article

Fabrication of three-dimensional scaffolds using precision extrusion deposition with an assisted cooling device

artículo científico publicado en 2011

Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors

artículo científico publicado en 2021

I2-mediated carbamate annulation: scope and application in the synthesis of azasugars

scientific article published on 23 March 2012

Identification and Biological Activity of Synthetic Macrophage Inducible C-Type Lectin Ligands

artículo científico publicado en 2017

Isolation and structural characterisation of the major glycolipids from Lactobacillus plantarum

artículo científico publicado en 2012

Lighting up sugars: fluorescent BODIPY–gluco-furanose and –septanose conjugates linked by direct B–O–C bonds

artículo científico publicado en 2016

Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine Adjuvants

artículo científico publicado en 2017

Long-Chain Lipids Are Required for the Innate Immune Recognition of Trehalose Diesters by Macrophages

scientific article published on 11 October 2011

MSU Crystals Enhance TDB-Mediated Inflammatory Macrophage IL-1β Secretion

scientific article published on 01 June 2019

Methyl 6-azido-6-de-oxy-α-d-galactoside

artículo científico publicado en 2011

Methyl 6-de-oxy-6-iodo-α-d-galactoside

artículo científico publicado en 2010

N,N-Bis(glycityl)amines as anti-cancer drugs

artículo científico publicado en 2016

N-(2-Acetamido-2-de-oxy-β-d-gluco-pyranos-yl)-N-(3-azido-prop-yl)-O-methyl-hydroxyl-amine

artículo científico publicado en 2016

On One Leg: Trehalose Monoesters Activate Macrophages in a Mincle-Dependent Manner

artículo científico publicado en 2014

Overexpression of Macrophage-Inducible C-Type Lectin Mincle Aggravates Proinflammatory Responses to Streptococcus pneumoniae with Fatal Outcome in Mice

artículo científico publicado en 2020

Probing glycomics

artículo científico publicado en 2007

Protecting-Group-Free Synthesis of Amines: Synthesis of Primary Amines from Aldehydes via Reductive Amination

scientific article published on 01 August 2010

Protecting-group-free synthesis of 2-deoxy-aza-sugars.

artículo científico publicado en 2009

Rapid synthesis of 1-deoxygalactonojirimycin using a carbamate annulation

Recent Developments in the Synthesis of Pyrrolidine-Containing Iminosugars

Recent Developments in the Synthesis of Pyrrolidine-Containing Iminosugars (Eur. J. Org. Chem. 9/2010)

Selective Cross-Metathesis of C-Allyl-glycosides

Selective Cross‐Metathesis ofC‐Allyl‐Glycosides

Short De Novo Synthesis of Fully Functionalized Uronic Acid Monosaccharides

artículo científico publicado en 2005

Species-Specific Activity of Glycolipid Ligands for Invariant NKT Cells

artículo científico publicado en 2012

Stereochemistry, lipid length and branching influences Mincle agonist activity of monoacylglycerides

artículo científico publicado en 2020

Stereocontrolled synthesis of fully functionalized D-glucosamine monosaccharides via a domino nitro-Michael/Henry reaction

artículo científico publicado en 2008

Stereoselective Strecker and Carbamate Annulation Methodology for the Synthesis of 1-Amino-1,2,5-trideoxy-2,5-imino-L-iditol

Stereoselective Total Synthesis of Aminoiminohexitols via Carbamate Annulation

artículo científico publicado en 2011

Synthesis and Biological Activity of the Lipoteichoic Acid Anchor fromStreptococcussp. DSM 8747

scientific article published on 11 October 2012

Synthesis and Hydrolytic Stability of N - and O -Methyloxyamine Linkers for the Synthesis of GlycoconjugatesSynthesis and Hydrolytic Stability of N - and O -Methyloxyamine Linkers for the Synthesis of Glycoconjugates

Synthesis and Investigation of Phthalazinones as Antitubercular Agents

scientific article published on 13 February 2019

Synthesis and anti-tuberculosis activity of glycitylamines

artículo científico publicado en 2015

Synthesis of Branched Trehalose Glycolipids and Their Mincle Agonist Activity

scientific article published on 12 June 2018

Synthesis of Functionalized Heterocycles via a Tandem Staudinger/Aza-Wittig/Ugi Multicomponent Reaction

Synthesis of functionalized heterocycles via a tandem Staudinger/aza-Wittig/Ugi multicomponent reaction

Synthesis of mycothiol conjugate analogues and evaluation of their antimycobacterial activity

artículo científico publicado en 2015

Synthesis of phosphorus mono- and bicycles by catalytic ring-closing metathesis

article published in 2001

Synthesis of α-Glucosyl Diacylglycerides as potential adjuvants for Streptococcus pneumoniae vaccines

scientific article published on 13 February 2020

The 'mirror-image' postulate as a guide to the selection and evaluation of pyrrolidines as α-l-fucosidase inhibitors

artículo científico publicado en 2012

The Ligands of C-Type Lectins

The Mincle ligand trehalose dibehenate differentially modulates M1-like and M2-like macrophage phenotype and function via Syk signaling.

artículo científico publicado en 2017

The Synthesis of Long-Chain α-Alkyl-β-Hydroxy Esters Using Allylic Halides in a Fráter-Seebach Alkylation

The Uptake of Trehalose Glycolipids by Macrophages Is Independent of Mincle

artículo científico publicado en 2015

The anti-cancer, anti-inflammatory and tuberculostatic activities of a series of 6,7-substituted-5,8-quinolinequinones.

artículo científico publicado en 2010

The co-administration of trehalose dibehenate and monosodium urate crystals promotes an anti-tumour phenotype in human-derived myeloid cells

artículo científico publicado en 2020

The effect of MR1 ligand glyco-analogues on mucosal-associated invariant T (MAIT) cell activation

scientific article published on 09 September 2019

The effects of trehalose glycolipid presentation on cytokine production by GM-CSF macrophages

artículo científico publicado en 2019

The modular synthesis of multivalent functionalised glycodendrons for the detection of lectins including DC-SIGN

artículo científico publicado en 2017

The rapid and facile synthesis of oxyamine linkers for the preparation of hydrolytically stable glycoconjugates.

artículo científico

The synthesis and evaluation of quinolinequinones as anti-mycobacterial agents

scientific article published on 01 June 2019

The use of a mannitol-derived fused oxacycle as a combinatorial scaffold

artículo científico publicado en 2003

The versatility of N-alkyl-methoxyamine bi-functional linkers for the preparation of glycoconjugates

artículo científico publicado en 2017

Total Synthesis Without Protecting Groups: Pyrrolidines and Cyclic Carbamates†

artículo científico publicado en 2009

Total synthesis of Lewis(X) using a late-stage crystalline intermediate

artículo científico

Total synthesis of aigialomycin D using a Ramberg-Bäcklund/RCM strategy

artículo científico publicado en 2009

Transformation of Glucose into a Novel Carbasugar Amino Acid Dipeptide Isostere

Transformation of Glucose into a Novel Carbasugar Amino Acid Dipeptide Isostere (IV)

Trehalose diesters, lipoteichoic acids and α-GalCer: using chemistry to understand immunology

artículo científico

Trehalose glycolipids--synthesis and biological activities

artículo científico

ortho-Substituted lipidated Brartemicin derivative shows promising Mincle-mediated adjuvant activity

scientific article published on 23 December 2019

Lista de obras de Mattie Timmer

A divergent approach to the synthesis of iGb3 sugar and lipid analogues via a lactosyl 2-azido-sphingosine intermediate

A fast, efficient and stereoselective synthesis of hydroxy-pyrrolidines.

A practical synthesis of gramicidin s and sugar amino Acid containing analogues.

A short route toward chiral, polyhydroxylated indolizidines and quinolizidines

Activation of type II NADH dehydrogenase by quinolinequinones mediates antitubercular cell death

Agonistic or antagonistic mucosal-associated invariant T (MAIT) cell activity is determined by the 6-alkylamino substituent on uracil MR1 ligands

Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties

An Expedient Synthesis of the Repeating Unit of the Acidic Polysaccharide of the Bacteriolytic Complex of Lysoamidase

An efficient synthesis of a 6″-BODIPY-α-Galactosylceramide probe for monitoring α-Galactosylceramide uptake by cells

An expeditious route to phosphorus heterocycles based on ring-closing metathesis

An improved synthesis of dansylated α-galactosylceramide and its use as a fluorescent probe for the monitoring of glycolipid uptake by cells

An unusual reverse turn structure adopted by a furanoid sugar amino acid incorporated in gramicidin S.

Applications and limitations of the I2-mediated carbamate annulation for the synthesis of piperidines: five- versus six-membered ring formation

Az—a colourful azulene-derived protecting group

Bi-analyte SERS with isotopically edited dyes

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

Carbohydrates as Versatile Platforms in the Construction of Small Compound Libraries

Carbohydrates as versatile platforms in the construction of small compound libraries

ChemInform Abstract: An Expeditious Route to Phosphorus Heterocycles Based on Ring-Closing Metathesis

ChemInform Abstract: Applications and Limitations of the I2-Mediated Carbamate Annulation for the Synthesis of Piperidines: Five- versus Six-Membered Ring Formation

ChemInform Abstract: Az - A Colorful Azulene-Derived Protecting Group

ChemInform Abstract: Chemical Tools for Studying the Biological Function of Glycolipids

ChemInform Abstract: I2-Mediated Carbamate Annulation: Scope and Application in the Synthesis of Aza-Sugars

ChemInform Abstract: Protecting-Group-Free Synthesis of Amines: Synthesis of Primary Amines from Aldehydes via Reductive Amination

ChemInform Abstract: Recent Developments in the Synthesis of Pyrrolidine-Containing Iminosugars

ChemInform Abstract: Stereocontrolled Synthesis of Fully Functionalized D-Glucosamine Monosaccharides via a Domino Nitro-Michael/Henry Reaction

ChemInform Abstract: Synthesis of Phosphorus Mono- and Bicycles by Catalytic Ring-Closing Metathesis

ChemInform Abstract: The Synthesis of Long-Chain α-Alkyl-β-hydroxy Esters Using Allylic Halides in a Frater-Seebach Alkylation

ChemInform Abstract: Total Synthesis of Aigialomycin D Using a Ramberg-Baecklund/RCM Strategy

ChemInform Abstract: Trehalose Glycolipids - Synthesis and Biological Activities

Chemical tools for studying the biological function of glycolipids

Claisen self-condensation/decarboxylation as the key steps in the synthesis of C2-symmetrical 1,7-dioxaspiro[5.5]undecanes

Cover Picture: Long-Chain Lipids Are Required for the Innate Immune Recognition of Trehalose Diesters by Macrophages (ChemBioChem 17/2011)

De Novo Synthesis of Aceric Acid and an Aceric Acid Building Block

De Novo Synthesis of Uronic Acid Building Blocks for Assembly of Heparin Oligosaccharides

De-novo-Synthese von vollständig funktionalisierten Uronsäure-Monosacchariden

Development of a benzophenone and alkyne functionalised trehalose probe to study trehalose dimycolate binding proteins

Diastereoselective Carbamate Annulation for the Synthesis of 2,5-Dideoxy-2,5-iminoglycitols

Discovery of lipids from B. longum subsp. infantis using whole cell MALDI analysis

Endogenous and Exogenous CD1-Binding Glycolipids

Fabrication of three-dimensional scaffolds using precision extrusion deposition with an assisted cooling device

Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors

I2-mediated carbamate annulation: scope and application in the synthesis of azasugars

Identification and Biological Activity of Synthetic Macrophage Inducible C-Type Lectin Ligands

Isolation and structural characterisation of the major glycolipids from Lactobacillus plantarum

Lighting up sugars: fluorescent BODIPY–gluco-furanose and –septanose conjugates linked by direct B–O–C bonds

Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine Adjuvants

Long-Chain Lipids Are Required for the Innate Immune Recognition of Trehalose Diesters by Macrophages

MSU Crystals Enhance TDB-Mediated Inflammatory Macrophage IL-1β Secretion

Methyl 6-azido-6-de-oxy-α-d-galactoside

Methyl 6-de-oxy-6-iodo-α-d-galactoside

N,N-Bis(glycityl)amines as anti-cancer drugs

N-(2-Acetamido-2-de-oxy-β-d-gluco-pyranos-yl)-N-(3-azido-prop-yl)-O-methyl-hydroxyl-amine

On One Leg: Trehalose Monoesters Activate Macrophages in a Mincle-Dependent Manner

Overexpression of Macrophage-Inducible C-Type Lectin Mincle Aggravates Proinflammatory Responses to Streptococcus pneumoniae with Fatal Outcome in Mice

Probing glycomics

Protecting-Group-Free Synthesis of Amines: Synthesis of Primary Amines from Aldehydes via Reductive Amination

Protecting-group-free synthesis of 2-deoxy-aza-sugars.

Rapid synthesis of 1-deoxygalactonojirimycin using a carbamate annulation

Recent Developments in the Synthesis of Pyrrolidine-Containing Iminosugars

Recent Developments in the Synthesis of Pyrrolidine-Containing Iminosugars (Eur. J. Org. Chem. 9/2010)

Selective Cross-Metathesis of C-Allyl-glycosides

Selective Cross‐Metathesis ofC‐Allyl‐Glycosides

Short De Novo Synthesis of Fully Functionalized Uronic Acid Monosaccharides

Species-Specific Activity of Glycolipid Ligands for Invariant NKT Cells

Stereochemistry, lipid length and branching influences Mincle agonist activity of monoacylglycerides

Stereocontrolled synthesis of fully functionalized D-glucosamine monosaccharides via a domino nitro-Michael/Henry reaction

Stereoselective Strecker and Carbamate Annulation Methodology for the Synthesis of 1-Amino-1,2,5-trideoxy-2,5-imino-L-iditol

Stereoselective Total Synthesis of Aminoiminohexitols via Carbamate Annulation

Synthesis and Biological Activity of the Lipoteichoic Acid Anchor fromStreptococcussp. DSM 8747

Synthesis and Hydrolytic Stability of N - and O -Methyloxyamine Linkers for the Synthesis of GlycoconjugatesSynthesis and Hydrolytic Stability of N - and O -Methyloxyamine Linkers for the Synthesis of Glycoconjugates

Synthesis and Investigation of Phthalazinones as Antitubercular Agents

Synthesis and anti-tuberculosis activity of glycitylamines

Synthesis of Branched Trehalose Glycolipids and Their Mincle Agonist Activity

Synthesis of Functionalized Heterocycles via a Tandem Staudinger/Aza-Wittig/Ugi Multicomponent Reaction

Synthesis of functionalized heterocycles via a tandem Staudinger/aza-Wittig/Ugi multicomponent reaction

Synthesis of mycothiol conjugate analogues and evaluation of their antimycobacterial activity

Synthesis of phosphorus mono- and bicycles by catalytic ring-closing metathesis

Synthesis of α-Glucosyl Diacylglycerides as potential adjuvants for Streptococcus pneumoniae vaccines