Lista de obras - Daniel Jun - Dominio Público Uruguay

7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment.

artículo científico publicado en 2015

A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication

artículo científico publicado en 2016

A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun-poisoned rats

scientific article published on 01 June 2007

A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats

artículo científico publicado en 2008

Acetylcholinesterase Inhibitors and Drugs Acting on Muscarinic Receptors- Potential Crosstalk of Cholinergic Mechanisms During Pharmacological Treatment

artículo científico publicado en 2016

Acetylcholinesterases--the structural similarities and differences

artículo científico publicado en 2007

Activity of cholinesterases in a young and healthy middle-European population: Relevance for toxicology, pharmacology and clinical praxis

artículo científico publicado en 2017

Amperometric Biosensors for Real Time Assays of Organophosphates

artículo científico publicado en 2008

An attempt to assess functionally minimal acetylcholinesterase activity necessary for survival of rats intoxicated with nerve agents.

artículo científico publicado en 2008

Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment

scientific article published on 17 March 2020

Bis-pyridiumaldoxime reactivators connected with CH2O(CH2)n OCH2 linkers between pyridinium rings and their reactivity against VX

artículo científico publicado en 2006

Bispyridinium oximes as antidotal treatment of cyclosarin poisoning-in vitro and in vivo testing

artículo científico publicado en 2005

Bisquaternary oximes as reactivators of tabun-inhibited human brain cholinesterases: an in vitro study

artículo científico publicado en 2007

Changes of acetylcholinesterase activity in different rat brain areas following intoxication with nerve agents: biochemical and histochemical study

artículo científico publicado en 2006

Changes of cholinesterase activities in the rat blood and brain after sarin intoxication pretreated with butyrylcholinesterase

artículo científico publicado en 2007

Characterization of the anticholinergic properties of obidoxime; functional examinations of the rat atria and the urinary bladder.

artículo científico publicado en 2010

Cholinergic properties of new 7-methoxytacrine-donepezil derivatives.

artículo científico publicado en 2014

Cholinesterase and Prolyl Oligopeptidase Inhibitory Activities of Alkaloids from Argemone platyceras (Papaveraceae).

artículo científico

Cholinesterase biosensor construction - a review.

artículo científico publicado en 2008

Cholinesterase reactivators: the fate and effects in the organism poisoned with organophosphates/nerve agents

artículo científico publicado en 2007

Comparison of ability of some oximes to reactivate sarin-inhibited brain acetylcholinesterase from different species

artículo científico publicado en 2005

Comparison of in vitro potency of oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited acetylcholinesterase in various parts of pig brain

artículo científico publicado en 2005

Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats

artículo científico publicado en 2007

Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo

scientific article published on 01 December 2005

Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro

artículo científico publicado en 2007

Cytotoxicity of acetylcholinesterase reactivators evaluated in vitro and its relation to their structure.

artículo científico publicado en 2018

DPPH Radical Scavenging Activity of Several Naturally Occurring Coumarins and Their Synthesized Analogs Measured by the SIA Method

artículo científico publicado en 2008

Daphnia intoxicated by nerve agent tabun can be treated using human antidotes.

artículo científico publicado en 2007

Design and synthesis of new bis-pyridinium oxime reactivators for acetylcholinesterase inhibited by organophosphorous nerve agents

artículo científico publicado en 2005

Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203).

artículo científico publicado en 2007

Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.

artículo científico publicado en 2015

Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.

artículo científico publicado en 2017

Effect of acetylcholinesterase oxime-type reactivators K-48 and HI-6 on human liver microsomal cytochromes P450 in vitro.

artículo científico publicado en 2009

Effect of some acetylcholinesterase reactivators on human platelet aggregation in vitro

artículo científico publicado en 2006

Effective bisquaternary reactivators of tabun-inhibited AChE.

artículo científico publicado en 2005

Efficacy and dosing of antidotes applied to Daphnia intoxicated by nerve agent tabun ⬇️

artículo científico publicado el 8 de junio de 2008

Erratum to “The influence of simvastatin, atorvastatin and high-cholesterol diet on acetylcholinesterase activity, amyloid beta and cholesterol synthesis in rat brain” [Steroids 74(January (1)) (2009) 13–19]

scholarly article published in Steroids

Evaluation of natural antioxidants of Leuzea carthamoides as a result of a screening study of 88 plant extracts from the European Asteraceae and Cichoriaceae

scientific article published on 01 April 2008

Evaluation of natural substances from Evolvulus alsinoides L. with the purpose of determining their antioxidant potency

scientific article published on 01 August 2008

Evaluation of reactivation test in anaesthetized dogs with experimental intoxication with nerve agents

artículo científico publicado en 2006

Evaluation of the antioxidant activity of several naturally occurring coumarins and their synthesized analogues by "ferric reducing antioxidant power" assay.

artículo científico publicado en 2013

Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors

scientific article published on 19 August 2019

Fluctuation in the ergosterol and deoxynivalenol content in barley and malt during malting process

artículo científico publicado en 2010

Hyaluronidase: its effects on HI-6 dichloride and dimethanesulphonate pharmacokinetic profile in pigs

artículo científico publicado en 2013

Improvement of acetylcholinesterase-based assay for organophosphates in way of identification by reactivators

artículo científico publicado en 2008

In Vitro Comparison of Two Most Promising H-Oximes (HI-6 and HLö-7) and Currently Commercially Available Reactivators Pralidoxime and Obidoxime in Reactivation of Cyclosarin-Inhibited Human Cholinesterases.

artículo científico publicado en 2008

In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier

scientific article published on 05 April 2019

In vitro antiplatelet activity of flavonoids from Leuzea carthamoides

artículo científico publicado en 2008

In vitro evaluation of acetylcholinesterase reactivators as potential antidotes against tabun nerve agent poisonings

artículo científico publicado en 2006

In vitro oxime-assisted reactivation of paraoxon-inhibited human acetylcholinesterase and butyrylcholinesterase.

artículo científico publicado en 2009

In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase

artículo científico publicado en 2006

In vitro reactivation of trichlorfon-inhibited butyrylcholinesterase using HI-6, obidoxime, pralidoxime and K048.

artículo científico publicado en 2009

In vitro reactivation potency of some acetylcholinesterase reactivators against sarin- and cyclosarin-induced inhibitions

artículo científico publicado en 2005

Inhibition of blood cholinesterases following intoxication with VX and its derivatives.

artículo científico publicado en 2007

Isoquinoline Alkaloids from Fumaria officinalis L. and Their Biological Activities Related to Alzheimer's Disease.

artículo científico publicado en 2016

Isoquinoline alkaloids as prolyl oligopeptidase inhibitors.

artículo científico publicado en 2015

Methylacridinium and its cholinergic properties.

artículo científico publicado en 2009

Molecular modeling studies on the interactions of aflatoxin B1 and its metabolites with the peripheral anionic site of human acetylcholinesterase

artículo científico publicado en 2018

Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

artículo científico publicado en 2007

Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase

artículo científico publicado en 2008

New antioxidant flavonoid isolated from Leuzea carthamoides.

artículo científico publicado en 2010

New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin

artículo científico publicado en 2006

Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation.

artículo científico publicado en 2017

Novel acetylcholinesterase reactivator K112 and its cholinergic properties.

artículo científico publicado en 2010

Novel bisquaternary oximes--reactivation of acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon

artículo científico publicado en 2009

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

artículo científico publicado en 2007

Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents.

artículo científico publicado en 2011

Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase.

artículo científico publicado en 2010

Phosphatidylinositol 3-Kinase (PI3K) and phosphatidylinositol 3-kinase-related kinase (PIKK) inhibitors: importance of the morpholine ring

artículo científico publicado en 2014

Photometric microplate assay for estimation of the efficacy of paraoxon-inhibited acetylcholinesterase reactivation

artículo científico publicado en 2008

Potency of five structurally different acetylcholinesterase reactivators to reactivate human brain cholinesterases inhibited by cyclosarin

artículo científico publicado en 2007

Potency of new structurally different oximes to reactivate cyclosarin-inhibited human brain acetylcholinesterases

artículo científico publicado en 2006

Potency of novel oximes to reactivate sarin inhibited human cholinesterases.

artículo científico publicado en 2008

Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro

artículo científico publicado en 2008

Preparation and characterization of methoxy polyethylene glycol-conjugated phosphotriesterase as a potential catalytic bioscavenger against organophosphate poisoning

artículo científico publicado en 2010

Preparation of benzalkonium salts differing in the length of a side alkyl chain

artículo científico publicado en 2007

Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium/isoquinolinium non-symmetrical bisquaternary cholinesterase inhibitors.

artículo científico publicado en 2013

Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning

scientific article published on 18 August 2006

Profiling donepezil template into multipotent hybrids with antioxidant properties

artículo científico publicado en 2018

Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006-2016).

artículo científico publicado en 2017

Prolyl oligopeptidase and its role in the organism: attention to the most promising and clinically relevant inhibitors

artículo científico

Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase

artículo científico publicado en 2010

RP-HPLC determination of the lipophilicity of bispyridinium reactivators of acetylcholinesterase bearing a but-2-ene connecting linker

artículo científico publicado en 2008

Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes

artículo científico publicado en 2008

Reactivation of VX-inhibited AChE by novel oximes having two oxygen atoms in the linker.

artículo científico publicado en 2010

Reactivation of human brain homogenate cholinesterases inhibited by Tabun using newly developed oximes K117 and K127.

artículo científico publicado en 2009

Russian VX: inhibition and reactivation of acetylcholinesterase compared with VX agent.

artículo científico publicado en 2006

SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides.

artículo científico publicado en 2016

Simple validated method of LC-MS/MS determination of BZ agent in rat plasma samples

artículo científico publicado en 2020

Simultaneous determination of malondialdehyde and 3-nitrotyrosine in cultured human hepatoma cells by liquid chromatography-mass spectrometry

scientific article published on 21 August 2018

Small Molecules Targeting Ataxia Telangiectasia and Rad3-Related (ATR) Kinase: An Emerging way to Enhance Existing Cancer Therapy

artículo científico publicado en 2016

Surface screening, molecular modeling and in vitro studies on the interactions of aflatoxin M1 and human enzymes acetyl- and butyrylcholinesterase

artículo científico publicado en 2019

Synthesis and Decontamination Effect on Chemical and Biological Agents of Benzoxonium-Like Salts

artículo científico publicado en 2021

Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy

artículo científico publicado en 2019

Synthesis and in vitro evaluation of N-(Bromobut-3-en-2-yl)-7-methoxy-1,2,3,4-tetrahydroacridin-9-amine as a cholinesterase inhibitor with regard to Alzheimer's disease treatment.

artículo científico publicado en 2010

Synthesis of (2E)-2-methyl-3-(4-([4-(quinolin-2-ylmethoxy)phenyl]sulfanyl)phenyl)prop-2-enoic acid (VUFB 20609) and 2-methyl-3-(4-([4-(quinolin-2-ylmethoxy)phenyl]sulfanyl)phenyl)propanoic acid (VUFB 20584) as potential antileukotrienic agents.

artículo científico publicado en 2004

Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

artículo científico publicado en 2005

Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

artículo científico publicado en 2007

Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

artículo científico publicado en 2006

Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase

artículo científico publicado en 2008

Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

artículo científico publicado en 2005

Synthesis, antimicrobial evaluation and molecular modeling of 5-hydroxyisoquinolinium salt series; the effect of the hydroxyl moiety

artículo científico publicado en 2016

Synthesis, in vitro acetylcholinesterase inhibitory activity and molecular docking of new acridine-coumarin hybrids

scientific article published on 07 June 2017

Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators

scientific article published on 01 December 2020

Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity.

artículo científico publicado en 2015

Targeted synthesis of 1-(4-hydroxyiminomethylpyridinium)-3-pyridiniumpropane dibromide--a new nerve agent reactivator.

artículo científico publicado en 2007

Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules.

artículo científico publicado en 2016

The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators

artículo científico publicado en 2016

The effect of oxime reactivators on muscarinic receptors: functional and binding examinations

artículo científico publicado en 2011

The influence of acetylcholinesterase reactivators on selected hepatic functions in rats

artículo científico publicado en 2008

The influence of simvastatin, atorvastatin and high-cholesterol diet on acetylcholinesterase activity, amyloid beta and cholesterol synthesis in rat brain

artículo científico publicado en 2008

The interaction of standard oxime reactivators with hemicholinium-3 sensitive choline carriers

artículo científico publicado en 2012

The reactivating and therapeutic efficacy of oximes to counteract Russian VX poisonings

artículo científico publicado en 2006

The summary on non-reactivation cholinergic properties of oxime reactivators: the interaction with muscarinic and nicotinic receptors ⬇️

artículo científico publicado el 21 de noviembre de 2012

Time-course changes of acetylcholinesterase activity in blood and some tissues in rats after intoxication by Russian VX.

artículo científico publicado en 2009

Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction.

artículo científico publicado en 2007

Trithiocyanurate complexes of iron, manganese and nickel and their anticholinesterase activity.

artículo científico publicado en 2014

Two step synthesis of a non-symmetric acetylcholinesterase reactivator

artículo científico publicado en 2007

Universality of Oxime K203 for Reactivation of Nerve Agent-Inhibited AChE

artículo científico publicado en 2015

Why acetylcholinesterase reactivators do not work in butyrylcholinesterase

artículo científico publicado en 2010

Lista de obras de Daniel Jun

7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment.

A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication

A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun-poisoned rats

A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats

Acetylcholinesterase Inhibitors and Drugs Acting on Muscarinic Receptors- Potential Crosstalk of Cholinergic Mechanisms During Pharmacological Treatment

Acetylcholinesterases--the structural similarities and differences

Activity of cholinesterases in a young and healthy middle-European population: Relevance for toxicology, pharmacology and clinical praxis

Amperometric Biosensors for Real Time Assays of Organophosphates

An attempt to assess functionally minimal acetylcholinesterase activity necessary for survival of rats intoxicated with nerve agents.

Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment

Bis-pyridiumaldoxime reactivators connected with CH2O(CH2)n OCH2 linkers between pyridinium rings and their reactivity against VX

Bispyridinium oximes as antidotal treatment of cyclosarin poisoning-in vitro and in vivo testing

Bisquaternary oximes as reactivators of tabun-inhibited human brain cholinesterases: an in vitro study

Changes of acetylcholinesterase activity in different rat brain areas following intoxication with nerve agents: biochemical and histochemical study

Changes of cholinesterase activities in the rat blood and brain after sarin intoxication pretreated with butyrylcholinesterase

Characterization of the anticholinergic properties of obidoxime; functional examinations of the rat atria and the urinary bladder.

Cholinergic properties of new 7-methoxytacrine-donepezil derivatives.

Cholinesterase and Prolyl Oligopeptidase Inhibitory Activities of Alkaloids from Argemone platyceras (Papaveraceae).

Cholinesterase biosensor construction - a review.

Cholinesterase reactivators: the fate and effects in the organism poisoned with organophosphates/nerve agents

Comparison of ability of some oximes to reactivate sarin-inhibited brain acetylcholinesterase from different species

Comparison of in vitro potency of oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited acetylcholinesterase in various parts of pig brain

Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats

Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo

Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro

Cytotoxicity of acetylcholinesterase reactivators evaluated in vitro and its relation to their structure.

DPPH Radical Scavenging Activity of Several Naturally Occurring Coumarins and Their Synthesized Analogs Measured by the SIA Method

Daphnia intoxicated by nerve agent tabun can be treated using human antidotes.

Design and synthesis of new bis-pyridinium oxime reactivators for acetylcholinesterase inhibited by organophosphorous nerve agents

Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203).

Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.

Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.

Effect of acetylcholinesterase oxime-type reactivators K-48 and HI-6 on human liver microsomal cytochromes P450 in vitro.

Effect of some acetylcholinesterase reactivators on human platelet aggregation in vitro

Effective bisquaternary reactivators of tabun-inhibited AChE.

Efficacy and dosing of antidotes applied to Daphnia intoxicated by nerve agent tabun ⬇️

Erratum to “The influence of simvastatin, atorvastatin and high-cholesterol diet on acetylcholinesterase activity, amyloid beta and cholesterol synthesis in rat brain” [Steroids 74(January (1)) (2009) 13–19]

Evaluation of natural antioxidants of Leuzea carthamoides as a result of a screening study of 88 plant extracts from the European Asteraceae and Cichoriaceae

Evaluation of natural substances from Evolvulus alsinoides L. with the purpose of determining their antioxidant potency

Evaluation of reactivation test in anaesthetized dogs with experimental intoxication with nerve agents

Evaluation of the antioxidant activity of several naturally occurring coumarins and their synthesized analogues by "ferric reducing antioxidant power" assay.

Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors

Fluctuation in the ergosterol and deoxynivalenol content in barley and malt during malting process

Hyaluronidase: its effects on HI-6 dichloride and dimethanesulphonate pharmacokinetic profile in pigs

Improvement of acetylcholinesterase-based assay for organophosphates in way of identification by reactivators

In Vitro Comparison of Two Most Promising H-Oximes (HI-6 and HLö-7) and Currently Commercially Available Reactivators Pralidoxime and Obidoxime in Reactivation of Cyclosarin-Inhibited Human Cholinesterases.

In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier

In vitro antiplatelet activity of flavonoids from Leuzea carthamoides

In vitro evaluation of acetylcholinesterase reactivators as potential antidotes against tabun nerve agent poisonings

In vitro oxime-assisted reactivation of paraoxon-inhibited human acetylcholinesterase and butyrylcholinesterase.

In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase

In vitro reactivation of trichlorfon-inhibited butyrylcholinesterase using HI-6, obidoxime, pralidoxime and K048.

In vitro reactivation potency of some acetylcholinesterase reactivators against sarin- and cyclosarin-induced inhibitions

Inhibition of blood cholinesterases following intoxication with VX and its derivatives.

Isoquinoline Alkaloids from Fumaria officinalis L. and Their Biological Activities Related to Alzheimer's Disease.

Isoquinoline alkaloids as prolyl oligopeptidase inhibitors.

Methylacridinium and its cholinergic properties.

Molecular modeling studies on the interactions of aflatoxin B1 and its metabolites with the peripheral anionic site of human acetylcholinesterase

Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase

New antioxidant flavonoid isolated from Leuzea carthamoides.

New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin

Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation.

Novel acetylcholinesterase reactivator K112 and its cholinergic properties.

Novel bisquaternary oximes--reactivation of acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents.

Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase.

Phosphatidylinositol 3-Kinase (PI3K) and phosphatidylinositol 3-kinase-related kinase (PIKK) inhibitors: importance of the morpholine ring

Photometric microplate assay for estimation of the efficacy of paraoxon-inhibited acetylcholinesterase reactivation

Potency of five structurally different acetylcholinesterase reactivators to reactivate human brain cholinesterases inhibited by cyclosarin

Potency of new structurally different oximes to reactivate cyclosarin-inhibited human brain acetylcholinesterases

Potency of novel oximes to reactivate sarin inhibited human cholinesterases.

Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro

Preparation and characterization of methoxy polyethylene glycol-conjugated phosphotriesterase as a potential catalytic bioscavenger against organophosphate poisoning

Preparation of benzalkonium salts differing in the length of a side alkyl chain

Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium/isoquinolinium non-symmetrical bisquaternary cholinesterase inhibitors.

Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning

Profiling donepezil template into multipotent hybrids with antioxidant properties