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Lista de obras de Fumihiko Hakuno

Constitutive expression of insulin receptor substrate (IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblasts

artículo científico publicado en 2011

Differential subcellular localization of insulin receptor substrates depends on C-terminal regions and importin beta

artículo científico publicado en 2008

Distinct modes of activation of phosphatidylinositol 3-kinase in response to cyclic adenosine 3', 5'-monophosphate or insulin-like growth factor I play different roles in regulation of cyclin D1 and p27Kip1 in FRTL-5 cells.

artículo científico publicado en 2008

Enhanced oxidative stress in GH-transgenic rat and acromegaly in humans

artículo científico publicado en 2012

Growth hormone (GH) or insulin-like growth factor (IGF)-I represses 11beta-hydroxysteroid dehydrogenase type 1 (HSD1) mRNA expression in 3T3-L1 cells and its activity in their homogenates.

artículo científico publicado en 2009

HSP90 interacting with IRS-2 is involved in cAMP-dependent potentiation of IGF-I signals in FRTL-5 cells

scientific journal article

Insulin receptor substrate-1 (IRS-1) forms a ribonucleoprotein complex associated with polysomes

artículo científico publicado en 2013

Insulin receptor substrate-3 functions as transcriptional activator in the nucleus

scientific journal article

Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity

artículo científico publicado en 2010

Insulin receptor substrates form high-molecular-mass complexes that modulate their availability to insulin/insulin-like growth factor-I receptor tyrosine kinases.

artículo científico publicado en 2010

Insulin-Like Growth Factor-l Potentiates Protein Synthesis Induced by Thyrotropin in FRTL-5 Cells: Comparison of Induction of Protein Synthesis and DNA Synthesis

artículo científico publicado el 1 de abril de 1998

Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs

artículo científico publicado en 2012

KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells.

artículo científico publicado en 2011

Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression

artículo científico publicado en 2004

Nexilin, a cardiomyopathy-associated F-actin binding protein, binds and regulates IRS1 signaling in skeletal muscle cells

artículo científico publicado en 2013

Novel missense mutation in the IGF-I receptor L2 domain results in intrauterine and postnatal growth retardation.

artículo científico publicado en 2012

Novel repressor regulates insulin sensitivity through interaction with Foxo1

artículo científico publicado en 2012

PKCα suppresses 7,12-dimethylbenz[a]anthracene-induced skin tumor formation

artículo científico publicado en 2012

PKCη promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 mRNA through suppression of JNK/c-Jun signaling under stress conditions

artículo científico publicado el 19 de mayo de 2011

Paraquat-induced oxidative stress represses phosphatidylinositol 3-kinase activities leading to impaired glucose uptake in 3T3-L1 adipocytes.

artículo científico publicado en 2010

Phosphatidylinositol 3-Kinase-Binding Protein, PI3KAP/XB130, Is Required for cAMP-induced Amplification of IGF Mitogenic Activity in FRTL-5 Thyroid Cells

artículo científico publicado el 11 de abril de 2012

Phosphatidylinositol 3-kinase (PI3K) activity bound to insulin-like growth factor-I (IGF-I) receptor, which is continuously sustained by IGF-I stimulation, is required for IGF-I-induced cell proliferation.

artículo científico publicado en 2012

The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation

artículo científico publicado en 2013

The novel roles of liver for compensation of insulin resistance in human growth hormone transgenic rats

artículo científico publicado en 2006