Lista de obras - Joao Relvas - Dominio Público Uruguay

BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype.

artículo científico publicado en 2009

Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance

artículo científico publicado en 2004

Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination.

artículo científico publicado en 2006

CNS integrins switch growth factor signalling to promote target-dependent survival

artículo científico publicado en 2002

Caveolin-1-mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype.

artículo científico publicado en 2017

Cdc42 and Rac1 Signaling Are Both Required for and Act Synergistically in the Correct Formation of Myelin Sheaths in the CNS

scientific article published on 01 October 2006

Collar occupancy: A new quantitative imaging tool for morphometric analysis of oligodendrocytes

artículo científico publicado en 2017

Daily alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior

scientific article published on 22 September 2020

Developmental regulation of alphav integrins produces functional changes in astrocyte behavior.

artículo científico publicado en 2001

Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage

artículo científico publicado en 2014

Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

scientific journal article

Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells

artículo científico publicado en 2014

Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation.

artículo científico publicado en 2017

Electrochemical Immunosensor for TNFα-Mediated Inflammatory Disease Screening

artículo científico publicado en 2019

Emerging Biosensing Technologies for Neuroinflammatory and Neurodegenerative Disease Diagnostics.

artículo científico publicado en 2018

Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development

artículo científico publicado en 2007

Evolvability of the actin cytoskeleton in oligodendrocytes during central nervous system development and aging

article

Expression of Rac1 alternative 3' UTRs is a cell specific mechanism with a function in dendrite outgrowth in cortical neurons

artículo científico publicado en 2017

Expression of dominant-negative and chimeric subunits reveals an essential role for beta1 integrin during myelination

artículo científico publicado en 2001

Extracellular environment contribution to astrogliosis-lessons learned from a tissue engineered 3D model of the glial scar

artículo científico publicado en 2015

Fluid ‘rope trick’ investigated

artículo científico publicado en 1998

Gelsolin is required for macrophage recruitment during remyelination of the peripheral nervous system

artículo científico publicado en 2010

Heterocellular Contacts with Mouse Brain Endothelial Cells Via Laminin and α6β1 Integrin Sustain Subventricular Zone (SVZ) Stem/Progenitor Cells Properties.

artículo científico publicado en 2016

Identification of New Interacting Partners for Atypical Rho GTPases: A SILAC-Based Approach

artículo científico publicado en 2012

Imbalance in habitual versus goal directed neural systems during symptom provocation in obsessive-compulsive disorder

artículo científico publicado en 2015

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system

scientific journal article

Jmy regulates oligodendrocyte differentiation via modulation of actin cytoskeleton dynamics

artículo científico publicado en 2018

Mechanical plasticity during oligodendrocyte differentiation and myelination

artículo científico publicado en 2017

Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells

artículo científico publicado en 2016

Microglia and alcohol meet at the crossroads: Microglia as critical modulators of alcohol neurotoxicity

artículo científico publicado en 2017

Modulation of oligodendrocyte differentiation and maturation by combined biochemical and mechanical cues

artículo científico publicado en 2016

Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells

artículo científico publicado en 2012

Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke.

artículo científico publicado en 2017

Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activation in Microglia and Hippocampal Neurons

scientific article published on 14 February 2020

Oligodendrocyte, Astrocyte, and Microglia Crosstalk in Myelin Development, Damage, and Repair

artículo científico publicado en 2016

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves

scientific journal article

Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4

artículo científico publicado en 2007

Profilin 1 is required for peripheral nervous system myelination.

artículo científico publicado en 2014

Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-α inhibitors

scientific journal article

Redox tuning of Ca2+ signaling in microglia drives glutamate release during hypoxia.

artículo científico publicado en 2018

Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia

artículo científico publicado en 2015

Regulation of neural progenitor proliferation and survival by beta1 integrins

artículo científico publicado en 2005

SCID mice containing muscle with human mitochondrial DNA mutations. An animal model for mitochondrial DNA defects.

artículo científico publicado en 1998

Small Rho GTPases are key regulators of peripheral nerve biology in health and disease.

artículo científico publicado en 2008

Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.

artículo científico publicado en 2009

Structure and function of a novel antioxidant peptide from the skin of tropical frogs

artículo científico publicado en 2017

TGF-?-treated microglia induce oligodendrocyte precursor cell chemotaxis through the HGF-c-Met pathway

artículo científico publicado en 2005

The ascorbate transporter SVCT2 to target microglia-dependent inflammation.

artículo científico publicado en 2017

The function of RhoGTPases in axon ensheathment and myelination

artículo científico publicado en 2008

The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool.

artículo científico publicado en 2011

Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia

scientific article published on 12 August 2016

c-Src deactivation by the polyphenol 3-O-caffeoylquinic acid abrogates reactive oxygen species-mediated glutamate release from microglia and neuronal excitotoxicity.

artículo científico publicado en 2014

c-Src function is necessary and sufficient for triggering microglial cell activation

artículo científico publicado en 2014

dMyc is required in retinal progenitors to prevent JNK-mediated retinal glial activation

artículo científico publicado en 2017

Lista de obras de Joao Relvas

BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype.

Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance

Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination.

CNS integrins switch growth factor signalling to promote target-dependent survival

Caveolin-1-mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype.

Cdc42 and Rac1 Signaling Are Both Required for and Act Synergistically in the Correct Formation of Myelin Sheaths in the CNS

Collar occupancy: A new quantitative imaging tool for morphometric analysis of oligodendrocytes

Daily alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior

Developmental regulation of alphav integrins produces functional changes in astrocyte behavior.

Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage

Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells

Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation.

Electrochemical Immunosensor for TNFα-Mediated Inflammatory Disease Screening

Emerging Biosensing Technologies for Neuroinflammatory and Neurodegenerative Disease Diagnostics.

Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development

Evolvability of the actin cytoskeleton in oligodendrocytes during central nervous system development and aging

Expression of Rac1 alternative 3' UTRs is a cell specific mechanism with a function in dendrite outgrowth in cortical neurons

Expression of dominant-negative and chimeric subunits reveals an essential role for beta1 integrin during myelination

Extracellular environment contribution to astrogliosis-lessons learned from a tissue engineered 3D model of the glial scar

Fluid ‘rope trick’ investigated

Gelsolin is required for macrophage recruitment during remyelination of the peripheral nervous system

Heterocellular Contacts with Mouse Brain Endothelial Cells Via Laminin and α6β1 Integrin Sustain Subventricular Zone (SVZ) Stem/Progenitor Cells Properties.

Identification of New Interacting Partners for Atypical Rho GTPases: A SILAC-Based Approach

Imbalance in habitual versus goal directed neural systems during symptom provocation in obsessive-compulsive disorder

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system

Jmy regulates oligodendrocyte differentiation via modulation of actin cytoskeleton dynamics

Mechanical plasticity during oligodendrocyte differentiation and myelination

Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells

Microglia and alcohol meet at the crossroads: Microglia as critical modulators of alcohol neurotoxicity

Modulation of oligodendrocyte differentiation and maturation by combined biochemical and mechanical cues

Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells

Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke.

Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activation in Microglia and Hippocampal Neurons

Oligodendrocyte, Astrocyte, and Microglia Crosstalk in Myelin Development, Damage, and Repair

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves

Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4

Profilin 1 is required for peripheral nervous system myelination.

Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-α inhibitors

Redox tuning of Ca2+ signaling in microglia drives glutamate release during hypoxia.

Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia

Regulation of neural progenitor proliferation and survival by beta1 integrins

SCID mice containing muscle with human mitochondrial DNA mutations. An animal model for mitochondrial DNA defects.

Small Rho GTPases are key regulators of peripheral nerve biology in health and disease.

Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.

Structure and function of a novel antioxidant peptide from the skin of tropical frogs

TGF-?-treated microglia induce oligodendrocyte precursor cell chemotaxis through the HGF-c-Met pathway

The ascorbate transporter SVCT2 to target microglia-dependent inflammation.

The function of RhoGTPases in axon ensheathment and myelination

The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool.

Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia

c-Src deactivation by the polyphenol 3-O-caffeoylquinic acid abrogates reactive oxygen species-mediated glutamate release from microglia and neuronal excitotoxicity.

c-Src function is necessary and sufficient for triggering microglial cell activation

dMyc is required in retinal progenitors to prevent JNK-mediated retinal glial activation