Lista de obras - Jean-François Ghersi-Egea

A new aspect of the protective functions of the blood-brain barrier: activities of four drug-metabolizing enzymes in isolated rat brain microvessels

artículo científico publicado en 1988

A simple method for evaluation of superoxide radical production in neural cells under various culture conditions: application to hypoxia.

artículo científico publicado en 1995

Active transport at the blood-CSF barrier contributes to manganese influx into the brain

artículo científico publicado en 2011

Are blood-brain interfaces efficient in protecting the brain from reactive molecules?

artículo científico publicado en 2001

Barriers to Drug Distribution into the Perinatal and Postnatal Brain

artículo científico publicado en 2018

Blood-brain barrier dysfunction in disorders of the developing brain

artículo científico publicado en 2015

Blood-brain interfaces: relevance to cerebral drug metabolism.

artículo científico publicado en 1995

Brain barrier systems: a new frontier in metal neurotoxicological research

artículo científico publicado en 2003

Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain.

artículo científico publicado en 2012

Brain mitochondrial cytochrome P-450scc: Spectral and catalytic properties

scientific article published on 01 May 1987

Brain protection at the blood-cerebrospinal fluid interface involves a glutathione-dependent metabolic barrier mechanism

artículo científico publicado en 2006

Capacity of rat brain to metabolize m-dinitrobenzene: an in vitro study

artículo científico publicado el 1 de enero de 1997

Changes in the cerebrospinal fluid circulatory system of the developing rat: quantitative volumetric analysis and effect on blood-CSF permeability interpretation.

artículo científico publicado en 2015

Changes of cerebral gamma glutamyltransferase activities after treatment with exogenous inducers

artículo científico publicado en 1987

Choroid plexus controls brain availability of anti-HIV nucleoside analogs via pharmacologically inhibitable organic anion transporters

artículo científico publicado en 2003

Choroid plexus glutathione peroxidases are instrumental in protecting the brain fluid environment from hydroperoxides during postnatal development

scientific article published on 27 June 2018

Cimetidine inhibits cerebral and hepatic mitochondrial respiration in rat.

artículo científico publicado en 1986

Clinical Imaging of Choroid Plexus in Health and in Brain Disorders: A Mini-Review

article

Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier.

artículo científico publicado en 2012

Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics

artículo científico publicado en 1999

Detoxification systems, passive and specific transport for drugs at the blood-CSF barrier in normal and pathological situations.

artículo científico publicado en 2004

Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide

scientific article published on 12 April 2019

Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces

artículo científico publicado en 2008

Drug metabolism in in vitro organotypic and cellular models of mammalian central nervous system: activities of membrane-bound epoxide hydrolase and NADPH-cytochrome P-450 (c) reductase.

artículo científico publicado en 1998

Drug metabolizing enzymes in the brain and cerebral microvessels

artículo científico publicado en 1991

Drug metabolizing enzymes in the rat pituitary gland

artículo científico publicado el 1 de enero de 1992

Efflux transporters in blood-brain interfaces of the developing brain

artículo científico publicado en 2015

Electronic spin resonance detection of superoxide and hydroxyl radicals during the reductive metabolism of drugs by rat brain preparations and isolated cerebral microvessels

artículo científico publicado en 1998

Enzyme mediated superoxide radical formation initiated by exogenous molecules in rat brain preparations

artículo científico publicado en 1991

Ethoxyresorufin O-deethylase activity in rat brain subcellular fractions

artículo científico publicado en 1987

Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries

artículo científico publicado en 1996

Glutathione Conjugation at the Blood-CSF Barrier Efficiently Prevents Exposure of the Developing Brain Fluid Environment to Blood-Borne Reactive Electrophilic Substances.

artículo científico publicado en 2018

Histopathologic and ultrastructural features and claudin expression in papillary tumors of the pineal region: a multicenter analysis

scientific article published on 01 June 2012

Impairment of blood-cerebrospinal fluid barrier properties by retrovirus-activated T lymphocytes: reduction in cerebrospinal fluid-to-blood efflux of prostaglandin E2.

artículo científico publicado en 2005

In vitro evidence that beta-amyloid peptide 1-40 diffuses across the blood-brain barrier and affects its permeability.

artículo científico publicado en 2000

In vivo study of the elimination from rat brain of an intracerebrally formed xenobiotic metabolite, 1-naphthyl-beta-D-glucuronide

artículo científico publicado en 1991

Inducibility of rat brain drug-metabolizing enzymes

artículo científico publicado en 1987

Induction and immunological characterization of the uridine diphosphate-glucuronosyltransferase conjugating 1-naphthol in the rat choroid plexus.

artículo científico publicado en 1994

Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study

artículo científico publicado en 2015

Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs.

artículo científico publicado en 1994

Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach.

artículo científico publicado en 2013

Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54

artículo científico publicado en 2006

Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by bilirubin at the blood-CSF and blood-brain barriers in the Gunn rat.

artículo científico publicado en 2011

Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease

artículo científico publicado en 2018

Molecular characterization of circumventricular organs and third ventricle ependyma in the rat: potential markers for periventricular tumors.

artículo científico publicado en 2012

N-acetylcysteine inhibits bacterial lipopeptide-mediated neutrophil transmigration through the choroid plexus in the developing brain

scientific article published on 23 January 2020

NADPH:cytochrome P-450(c) reductase: biochemical characterization in rat brain and cultured neurons and evolution of activity during development.

artículo científico publicado en 1989

Nicotine raises the influx of permeable solutes across the rat blood-brain barrier with little or no capillary recruitment

artículo científico publicado en 1995

Novel routes to either racemic or enantiopure α-amino-(4-hydroxy-pyrrolidin-3-yl)acetic acid derivatives and biological evaluation of a new promising pharmacological scaffold

artículo científico publicado en 2015

P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) localize in the microvessels forming the blood-tumor barrier in ependymomas

artículo científico publicado en 2010

Posttraumatic invasion of monocytes across the blood-cerebrospinal fluid barrier

artículo científico publicado en 2011

Potential Pathways for CNS Drug Delivery Across the Blood-Cerebrospinal Fluid Barrier

artículo científico publicado en 2016

Pro-inflammatory cytokines modulate matrix metalloproteinase secretion and organic anion transport at the blood-cerebrospinal fluid barrier

artículo científico publicado en 2003

Prostaglandin E2 metabolism in rat brain: Role of the blood-brain interfaces

artículo científico publicado en 2008

Quantitative measurement of cerebral cytochrome P-450 by second derivative spectrophotometry

artículo científico publicado en 1987

Rapid distribution of intraventricularly administered sucrose into cerebrospinal fluid cisterns via subarachnoid velae in rat.

artículo científico publicado en 1996

Rat choroid plexuses contain myeloid progenitors capable of differentiation toward macrophage or dendritic cell phenotypes

artículo científico publicado en 2006

Regional brain variations of cytochrome oxidase activity and motor coordination in Lurcher mutant mice

artículo científico publicado en 1998

Rôles biologiques des éléments traces dans le cerveau – exemples du Zn et du Fe

artículo científico publicado en 2010

Subcellular distribution of cytochrome P-450 in the brain

artículo científico publicado en 1986

Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain

artículo científico publicado en 1993

Symposium overview: the role of glutathione in neuroprotection and neurotoxicity

artículo científico publicado en 1999

T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium

artículo científico publicado en 2016

The activity of 1-naphthol-UDP-glucuronosyltransferase in the brain

artículo científico publicado en 1987

The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher.

artículo científico publicado en 2015

The rapid flow of cerebrospinal fluid from ventricles to cisterns via subarachnoid velae in the normal rat

artículo científico publicado en 1997

The role of the choroid plexus in neutrophil invasion after traumatic brain injury.

artículo científico publicado en 2009

Toxic shock syndrome toxin-1 challenges the neuroprotective functions of the choroidal epithelium and induces neurotoxicity.

artículo científico publicado en 2006

Transport and metabolism at blood-brain interfaces and in neural cells: relevance to bilirubin-induced encephalopathy.

artículo científico publicado en 2012

Uridine diphosphate-glucuronosyltransferase activities in rat brain microsomes

artículo científico publicado en 1993

[The choroid plexuses: a dynamic interface between the blood and the cerebrospinal fluid]

scientific article published on 01 June 2005

Lista de obras de Jean-François Ghersi-Egea

A new aspect of the protective functions of the blood-brain barrier: activities of four drug-metabolizing enzymes in isolated rat brain microvessels

A simple method for evaluation of superoxide radical production in neural cells under various culture conditions: application to hypoxia.

Active transport at the blood-CSF barrier contributes to manganese influx into the brain

Are blood-brain interfaces efficient in protecting the brain from reactive molecules?

Barriers to Drug Distribution into the Perinatal and Postnatal Brain

Blood-brain barrier dysfunction in disorders of the developing brain

Blood-brain interfaces: relevance to cerebral drug metabolism.

Brain barrier systems: a new frontier in metal neurotoxicological research

Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain.

Brain mitochondrial cytochrome P-450scc: Spectral and catalytic properties

Brain protection at the blood-cerebrospinal fluid interface involves a glutathione-dependent metabolic barrier mechanism

Capacity of rat brain to metabolize m-dinitrobenzene: an in vitro study

Changes in the cerebrospinal fluid circulatory system of the developing rat: quantitative volumetric analysis and effect on blood-CSF permeability interpretation.

Changes of cerebral gamma glutamyltransferase activities after treatment with exogenous inducers

Choroid plexus controls brain availability of anti-HIV nucleoside analogs via pharmacologically inhibitable organic anion transporters

Choroid plexus glutathione peroxidases are instrumental in protecting the brain fluid environment from hydroperoxides during postnatal development

Cimetidine inhibits cerebral and hepatic mitochondrial respiration in rat.

Clinical Imaging of Choroid Plexus in Health and in Brain Disorders: A Mini-Review

Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier.

Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics

Detoxification systems, passive and specific transport for drugs at the blood-CSF barrier in normal and pathological situations.

Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide

Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces

Drug metabolism in in vitro organotypic and cellular models of mammalian central nervous system: activities of membrane-bound epoxide hydrolase and NADPH-cytochrome P-450 (c) reductase.

Drug metabolizing enzymes in the brain and cerebral microvessels

Drug metabolizing enzymes in the rat pituitary gland

Efflux transporters in blood-brain interfaces of the developing brain

Electronic spin resonance detection of superoxide and hydroxyl radicals during the reductive metabolism of drugs by rat brain preparations and isolated cerebral microvessels

Enzyme mediated superoxide radical formation initiated by exogenous molecules in rat brain preparations

Ethoxyresorufin O-deethylase activity in rat brain subcellular fractions

Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries

Glutathione Conjugation at the Blood-CSF Barrier Efficiently Prevents Exposure of the Developing Brain Fluid Environment to Blood-Borne Reactive Electrophilic Substances.

Histopathologic and ultrastructural features and claudin expression in papillary tumors of the pineal region: a multicenter analysis

Impairment of blood-cerebrospinal fluid barrier properties by retrovirus-activated T lymphocytes: reduction in cerebrospinal fluid-to-blood efflux of prostaglandin E2.

In vitro evidence that beta-amyloid peptide 1-40 diffuses across the blood-brain barrier and affects its permeability.

In vivo study of the elimination from rat brain of an intracerebrally formed xenobiotic metabolite, 1-naphthyl-beta-D-glucuronide

Inducibility of rat brain drug-metabolizing enzymes

Induction and immunological characterization of the uridine diphosphate-glucuronosyltransferase conjugating 1-naphthol in the rat choroid plexus.

Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study

Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs.

Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach.

Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54

Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by bilirubin at the blood-CSF and blood-brain barriers in the Gunn rat.

Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease

Molecular characterization of circumventricular organs and third ventricle ependyma in the rat: potential markers for periventricular tumors.

N-acetylcysteine inhibits bacterial lipopeptide-mediated neutrophil transmigration through the choroid plexus in the developing brain

NADPH:cytochrome P-450(c) reductase: biochemical characterization in rat brain and cultured neurons and evolution of activity during development.

Nicotine raises the influx of permeable solutes across the rat blood-brain barrier with little or no capillary recruitment

Novel routes to either racemic or enantiopure α-amino-(4-hydroxy-pyrrolidin-3-yl)acetic acid derivatives and biological evaluation of a new promising pharmacological scaffold

P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) localize in the microvessels forming the blood-tumor barrier in ependymomas

Posttraumatic invasion of monocytes across the blood-cerebrospinal fluid barrier

Potential Pathways for CNS Drug Delivery Across the Blood-Cerebrospinal Fluid Barrier

Pro-inflammatory cytokines modulate matrix metalloproteinase secretion and organic anion transport at the blood-cerebrospinal fluid barrier

Prostaglandin E2 metabolism in rat brain: Role of the blood-brain interfaces

Quantitative measurement of cerebral cytochrome P-450 by second derivative spectrophotometry

Rapid distribution of intraventricularly administered sucrose into cerebrospinal fluid cisterns via subarachnoid velae in rat.

Rat choroid plexuses contain myeloid progenitors capable of differentiation toward macrophage or dendritic cell phenotypes

Regional brain variations of cytochrome oxidase activity and motor coordination in Lurcher mutant mice

Rôles biologiques des éléments traces dans le cerveau – exemples du Zn et du Fe

Subcellular distribution of cytochrome P-450 in the brain

Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain

Symposium overview: the role of glutathione in neuroprotection and neurotoxicity

T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium

The activity of 1-naphthol-UDP-glucuronosyltransferase in the brain

The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher.

The rapid flow of cerebrospinal fluid from ventricles to cisterns via subarachnoid velae in the normal rat

The role of the choroid plexus in neutrophil invasion after traumatic brain injury.

Toxic shock syndrome toxin-1 challenges the neuroprotective functions of the choroidal epithelium and induces neurotoxicity.

Transport and metabolism at blood-brain interfaces and in neural cells: relevance to bilirubin-induced encephalopathy.

Uridine diphosphate-glucuronosyltransferase activities in rat brain microsomes

[The choroid plexuses: a dynamic interface between the blood and the cerebrospinal fluid]