Lista de obras - Tally Largent-milnes - Dominio Público Uruguay

17-β-Estradiol induces spreading depression and pain behavior in alert female rats

artículo científico publicado en 2017

A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain.

artículo científico publicado en 2018

A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction

artículo científico publicado en 2019

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss

artículo científico publicado en 2010

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors

artículo científico publicado en 2015

A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists

artículo científico publicado en 2008

Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E₂ in the spinal cord

artículo científico publicado en 2011

Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents

scientific article published on 13 April 2020

Acute visceral pain relief mediated by A3AR agonists in rats: involvement of N-type voltage-gated calcium channels

artículo científico publicado en 2020

An underrepresented majority: A systematic review utilizing allodynic criteria to examine the present scarcity of discrete animal models for episodic migraine

artículo científico publicado en 2020

Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain

artículo científico publicado en 2016

Animal Models for the Study of Bone-Derived Pain

scientific article published on 01 January 2019

Animal models for opioid addiction drug discovery

artículo científico publicado en 2014

Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects.

artículo científico publicado en 2013

Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats

artículo científico publicado en 2014

Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain

scientific article published on 26 July 2018

Cerebral arteriolar and neurovascular dysfunction after chemically-induced menopause in mice

artículo científico publicado en 2022

Chronic morphine exposure potentiates p-glycoprotein trafficking from nuclear reservoirs in cortical rat brain microvessels.

artículo científico publicado en 2018

Continuous Remote Ischemic Conditioning Attenuates Cognitive and Motor Deficits From Moderate Traumatic Brain Injury.

artículo científico publicado en 2018

DAGLα Inhibition as a Non-invasive and Translational Model of Episodic Headache

scientific article published in 2021

Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives

artículo científico publicado en 2015

Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands

artículo científico publicado en 2015

Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain

artículo científico publicado en 2015

Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies

artículo científico publicado en 2011

Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists

artículo científico publicado en 2013

Effect of Centruroides antivenom on reversal of methamphetamine-induced hyperkinesis and hyperthermia in rats

artículo científico publicado en 2017

Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations

artículo científico publicado en 2015

External QX-314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV1.

artículo científico publicado en 2014

Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake

artículo científico publicado en 2020

Glial neuroimmune signaling in opioid reward

artículo científico publicado en 2019

Heat shock protein 90 inhibitors block the anti-nociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models

scientific article published on 10 April 2020

Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats

artículo científico publicado en 2011

Long-lasting antinociceptive effects of green light in acute and chronic pain in rats.

artículo científico publicado en 2017

Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery.

artículo científico publicado en 2018

Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors

artículo científico publicado en 2008

Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain

artículo científico publicado en 2011

Oxycodone plus ultra-low-dose naltrexone attenuates neuropathic pain and associated mu-opioid receptor-Gs coupling

artículo científico publicado en 2008

Peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain

scientific article published on 01 September 2018

Physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons

artículo científico publicado en 2014

Recently patented and promising ORL-1 ligands: where have we been and where are we going?

artículo científico publicado en 2010

Remote ischemic conditioning preserves cognition and motor coordination in a mouse model of traumatic brain injury

artículo científico publicado en 2017

Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist

artículo científico publicado en 2012

Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats

artículo científico publicado en 2021

Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain

scientific article published on 08 May 2019

Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance.

artículo científico publicado en 2010

Structure-Activity Relationships of [des-Arg7]Dynorphin A Analogues at the κ Opioid Receptor

artículo científico publicado en 2016

Sustained morphine-mediated pain sensitization and antinociceptive tolerance are blocked by intrathecal treatment with Raf-1-selective siRNA.

artículo científico publicado en 2010

Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists

artículo científico publicado en 2016

Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects

artículo científico publicado en 2020

Tachykinin NK₁ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation

artículo científico publicado en 2012

Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation

artículo científico publicado en 2017

Temperature differentially facilitates spontaneous but not evoked glutamate release from cranial visceral primary afferents

artículo científico publicado en 2015

The Effects of Repeated Morphine Treatment on the Endogenous Cannabinoid System in the Ventral Tegmental Area

artículo científico publicado en 2021

The cystine/glutamate antiporter system xc- drives breast tumor cell glutamate release and cancer-induced bone pain

artículo científico publicado en 2016

Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities

scientific article published on 02 July 2013

Use of Animal Models in Understanding Cancer-induced Bone Pain

artículo científico publicado en 2015

Lista de obras de Tally Largent-milnes

17-β-Estradiol induces spreading depression and pain behavior in alert female rats

A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain.

A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors

A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists

Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E₂ in the spinal cord

Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents

Acute visceral pain relief mediated by A3AR agonists in rats: involvement of N-type voltage-gated calcium channels

An underrepresented majority: A systematic review utilizing allodynic criteria to examine the present scarcity of discrete animal models for episodic migraine

Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain

Animal Models for the Study of Bone-Derived Pain

Animal models for opioid addiction drug discovery

Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects.

Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats

Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain

Cerebral arteriolar and neurovascular dysfunction after chemically-induced menopause in mice

Chronic morphine exposure potentiates p-glycoprotein trafficking from nuclear reservoirs in cortical rat brain microvessels.

Continuous Remote Ischemic Conditioning Attenuates Cognitive and Motor Deficits From Moderate Traumatic Brain Injury.

DAGLα Inhibition as a Non-invasive and Translational Model of Episodic Headache

Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives

Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands

Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain

Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies

Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists

Effect of Centruroides antivenom on reversal of methamphetamine-induced hyperkinesis and hyperthermia in rats

Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations

External QX-314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV1.

Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake

Glial neuroimmune signaling in opioid reward

Heat shock protein 90 inhibitors block the anti-nociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models

Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats

Long-lasting antinociceptive effects of green light in acute and chronic pain in rats.

Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery.

Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors

Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain

Oxycodone plus ultra-low-dose naltrexone attenuates neuropathic pain and associated mu-opioid receptor-Gs coupling

Peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain

Physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons

Recently patented and promising ORL-1 ligands: where have we been and where are we going?

Remote ischemic conditioning preserves cognition and motor coordination in a mouse model of traumatic brain injury

Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist

Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats

Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain

Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance.

Structure-Activity Relationships of [des-Arg7]Dynorphin A Analogues at the κ Opioid Receptor

Sustained morphine-mediated pain sensitization and antinociceptive tolerance are blocked by intrathecal treatment with Raf-1-selective siRNA.

Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists

Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects

Tachykinin NK₁ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation

Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation

Temperature differentially facilitates spontaneous but not evoked glutamate release from cranial visceral primary afferents

The Effects of Repeated Morphine Treatment on the Endogenous Cannabinoid System in the Ventral Tegmental Area

The cystine/glutamate antiporter system xc- drives breast tumor cell glutamate release and cancer-induced bone pain

Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities

Use of Animal Models in Understanding Cancer-induced Bone Pain