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Lista de obras de Colin Dunstan

A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.

artículo científico publicado en 1999

A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases

artículo científico publicado en 2003

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women

artículo científico publicado en 2004

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women. 2004.

artículo científico publicado en 2005

A toxicity profile of osteoprotegerin in the cynomolgus monkey

artículo científico publicado en 2003

Accelerated bone resorption, due to dietary calcium deficiency, promotes breast cancer tumor growth in bone.

artículo científico publicado en 2007

Activation and promotion of adipose stem cells by tumour necrosis factor-α preconditioning for bone regeneration

artículo científico publicado en 2013

Activation of the pro-migratory bone morphogenetic protein receptor 1B gene in human MDA-MB-468 triple-negative breast cancer cells that over-express CYP2J2.

artículo científico

Adenoviral delivery of osteoprotegerin ameliorates bone resorption in a mouse ovariectomy model of osteoporosis

artículo científico publicado en 2001

Adult osteosclerosis

artículo científico publicado en 1983

Aluminium-related bone disease presenting with calcaneal stress fractures

artículo científico publicado en 1993

Aluminum and renal bone disease in Australia

artículo científico publicado en 1986

Baghdadite ceramics modulate the cross talk between human adipose stem cells and osteoblasts for bone regeneration

artículo científico publicado en 2013

Biphasic glucocorticoid-dependent regulation of Wnt expression and its inhibitors in mature osteoblastic cells

artículo científico publicado en 2009

Bone balance within a cortical BMU: local controls of bone resorption and formation.

artículo científico publicado en 2012

Bone death in hip fracture in the elderly

artículo científico publicado en 1990

Bone death in transient regional osteoporosis

artículo científico publicado en 1992

Bone growth is enhanced by novel bioceramic coatings on Ti alloy implants

artículo científico publicado en 2009

Bone loss after liver transplantation

artículo científico publicado en 1991

Bone metabolism in chronic renal failure

artículo científico publicado en 1982

Bone metabolism in idiopathic juvenile osteoporosis: a case report

artículo científico publicado en 1983

Bone metabolism in systemic mastocytosis. A case report

artículo científico publicado en 1981

Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts

scientific article published on 01 March 1997

Bone resorption caused by three periodontal pathogens in vivo in mice is mediated in part by prostaglandin.

artículo científico publicado en 1998

Bone resorption increases tumour growth in a mouse model of osteosclerotic breast cancer metastasis

scientific article published on 18 April 2008

Burning daylight: balancing vitamin D requirements with sensible sun exposure

artículo científico publicado en 2011

CXCL12/CXCR4 axis in tissue targeting and bone destruction in cancer and multiple myeloma

artículo científico publicado en 2009

Calcification in atherosclerosis: bone biology and chronic inflammation at the arterial crossroads.

artículo científico publicado en 2003

Cellular activity and signaling induced by osteoprotegerin in osteoclasts: involvement of receptor activator of nuclear factor kappaB ligand and MAPK.

artículo científico publicado en 2004

Characterisation of a novel light activated adhesive scaffold: Potential for device attachment.

artículo científico publicado en 2016

Characterization of osteoclast precursors in human blood

scientific article published on 01 November 2000

Clinical review 165: Markers of bone remodeling in metastatic bone disease.

artículo científico publicado en 2003

Colonic dendritic cells, intestinal inflammation, and T cell-mediated bone destruction are modulated by recombinant osteoprotegerin

artículo científico publicado en 2003

Combined treatment with PTH (1-34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats.

artículo científico publicado en 2005

Computational modeling of interactions between multiple myeloma and the bone microenvironment

artículo científico publicado en 2011

Correction: The 18 kDa Translocator Protein (Peripheral Benzodiazepine Receptor) Expression in the Bone of Normal, Osteoprotegerin or Low Calcium Diet Treated Mice.

artículo científico publicado en 2012

Correlates of osteoprotegerin levels in women and men.

artículo científico publicado en 2002

Corticosterone selectively targets endo-cortical surfaces by an osteoblast-dependent mechanism

artículo científico publicado en 2011

Direct crosstalk between cancer and osteoblast lineage cells fuels metastatic growth in bone via auto-amplification of IL-6 and RANKL signaling pathways.

artículo científico publicado en 2014

E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model

scientific article published on 01 September 1996

Effect of EstrogenversusTestosterone on Circulating Osteoprotegerin and Other Cytokine Levels in Normal Elderly Men

Effect of aluminum and parathyroid hormone on osteoblasts and bone mineralization in chronic renal failure.

artículo científico publicado en 1984

Effect of aluminum on normal and uremic rats: tissue distribution, vitamin D metabolites, and quantitative bone histology

artículo científico publicado en 1983

Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men.

artículo científico publicado en 2002

Effect of osteoprotegerin and pamidronate treatment in transgenic mice overexpressing human TNF.

artículo científico publicado en 2001

Effects of human tumor cell lines on local new bone formation in vivo

scientific article published on 01 February 1997

Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells

artículo científico publicado en 2001

Efficacy of novel synthetic bone substitutes in the reconstruction of large segmental bone defects in sheep tibiae

artículo científico publicado en 2016

Endogenous glucocorticoid signalling in osteoblasts is necessary to maintain normal bone structure in mice.

artículo científico publicado en 2009

Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells

artículo científico publicado en 1999

Evidence for anti-osteoporosis therapy in acute fracture situations--recommendations of a multidisciplinary workshop of the International Society for Fracture Repair

artículo científico publicado en 2009

Evidence that type I osteoporosis results from enhanced responsiveness of bone to estrogen deficiency.

artículo científico publicado en 2003

Fibroblast growth factor 23: a phosphatonin regulating phosphate homeostasis?

artículo científico publicado en 2004

Follicle-stimulating hormone increases bone mass in female mice

artículo científico publicado en 2010

Fracture behaviors of ceramic tissue scaffolds for load bearing applications.

artículo científico publicado en 2016

Genetic and hormonal control of bone volume, architecture, and remodeling in XXY mice

artículo científico publicado en 2010

Glucocorticoid-dependent Wnt signaling by mature osteoblasts is a key regulator of cranial skeletal development in mice

artículo científico publicado en 2009

Growth and dissemination of a newly-established murine B-cell lymphoma cell line is inhibited by multimeric YIGSR peptide.

artículo científico publicado en 1998

Growth retardation and renal osteodystrophy in children with chronic renal failure

scientific article published on 01 November 1983

Histomorphological and torque removal comparison of 6 mm orthodontic miniscrews with and without surface treatment in New Zealand rabbits

artículo científico publicado en 2015

Human amniotic tumor that induces new bone formation in vivo produces growth-regulatory activity in vitro for osteoblasts identified as an extended form of basic fibroblast growth factor

artículo científico publicado en 1996

Hypothesis: bones toughness arises from the suppression of elastic waves

artículo científico publicado en 2014

Immobilisation hypercalcemia

scientific article published on 01 January 1984

Immobilization hypercalcaemia due to low bone formation and responding to intravenous sodium sulphate

artículo científico publicado en 1986

Increased bone formation in osteocalcin-deficient mice.

artículo científico publicado en 1996

Inhibition of bone resorption, rather than direct cytotoxicity, mediates the anti-tumour actions of ibandronate and osteoprotegerin in a murine model of breast cancer bone metastasis.

artículo científico publicado en 2006

Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.

artículo científico publicado en 1997

Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells

artículo científico publicado en 1999

Isolated and combined inhibition of TNF-, IL-1 and RANKL-pathways in TNF-induced arthritis: effects on synovial inflammation, bone erosion and cartilage destruction

Lack of metabolic bone disease in patients with fracture of the femoral neck

scientific article published on 01 April 1981

Long-term experience with a calcium-thiazide treatment for Paget's disease of bone

artículo científico publicado en 1982

Mathematical modeling of postmenopausal osteoporosis and its treatment by the anti-catabolic drug denosumab.

artículo científico publicado en 2013

Measurement of osteoclasts and bone resorption by automated image analysis

artículo científico publicado en 1993

Mechanisms of disease: roles of OPG, RANKL and RANK in the pathophysiology of skeletal metastasis.

artículo científico publicado en 2006

Metabolic studies in kidney stone disease

artículo científico publicado en 1992

Mitogenic lectin concanavalin A induces calvarial bone formation in vivo via indomethacin-sensitive pathway

artículo científico publicado en 1997

Model structure and control of bone remodeling: a theoretical study.

artículo científico publicado en 2008

OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats

artículo científico publicado en 2001

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

scientific journal article

Osteoblast-targeted disruption of glucocorticoid signalling does not delay intramembranous bone healing.

artículo científico publicado en 2010

Osteoblasts mediate the adverse effects of glucocorticoids on fuel metabolism.

artículo científico publicado en 2012

Osteocyte death and hip fracture

artículo científico publicado en 1993

Osteoprotegerin ameliorates sciatic nerve crush induced bone loss

scientific article published on 01 July 2001

Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors

artículo científico publicado en 1999

Osteoprotegerin differentially regulates protease expression in osteoclast cultures

artículo científico publicado en 2002

Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis

artículo científico publicado en 2001

Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma

artículo científico publicado en 2001

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

artículo científico publicado en 1998

Osteoprotegerin mitigates tail suspension-induced osteopenia

scientific article published on 01 May 2000

Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy.

artículo científico publicado en 2000

Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines

artículo científico publicado en 1998

Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice

artículo científico publicado en 2003

Osteoprotegerin protects from generalized bone loss in TNF-transgenic mice.

artículo científico publicado en 2003

Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis

artículo científico publicado en 2002

Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis

artículo científico publicado en 2000

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

artículo científico publicado en 1997

Pathologic fracture due to severe osteomalacia following low-dose diphosphonate treatment of Paget's disease of bone

scientific article published on 01 June 1983

Priming Adipose Stem Cells with Tumor Necrosis Factor-Alpha Preconditioning Potentiates Their Exosome Efficacy for Bone Regeneration.

artículo científico publicado en 2017

Prurigo nodularis and aluminium overload in maintenance haemodialysis

artículo científico publicado en 1992

Quantitative bone histology in children with chronic renal failure

artículo científico publicado en 1982

Quantitative bone histology in end-stage renal failure

artículo científico publicado en 1980

Quantitative bone histology in the hypercalcemia of malignant disease

scientific article published on 01 December 1982

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

artículo científico publicado en 2000

RANK ligand

artículo científico publicado en 2006

Rationale for the role of osteoclast-like cells in arterial calcification

artículo científico publicado en 2002

Recovery from steroid-induced osteoporosis

artículo científico publicado en 1987

Regulation of osteoclast protease expression by RANKL.

artículo científico publicado en 2003

Repairing a critical-sized bone defect with highly porous modified and unmodified baghdadite scaffolds

artículo científico publicado en 2012

Role of mathematical modeling in bone fracture healing.

artículo científico publicado en 2012

Serum cathepsin K concentrations reflect osteoclastic activity in women with postmenopausal osteoporosis and patients with Paget's disease.

artículo científico publicado en 2006

Serum osteoprotegerin levels are increased in patients with advanced prostate cancer

artículo científico publicado en 2001

Serum osteoprotegerin levels in healthy controls and cancer patients

scientific article published on 01 July 2002

Sex Steroids, Not FSH, Influence Bone Mass

artículo científico publicado en 2006

Short-Term Exposure to Tumor Necrosis Factor-Alpha Enables Human Osteoblasts to Direct Adipose Tissue-Derived Mesenchymal Stem Cells into Osteogenic Differentiation ⬇️

artículo científico publicado el 6 de marzo de 2012

Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destruction

artículo científico publicado en 2004

Sphene ceramics for orthopedic coating applications: an in vitro and in vivo study.

artículo científico publicado en 2009

Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis

artículo científico publicado en 1999

Suramin suppresses hypercalcemia and osteoclastic bone resorption in nude mice bearing a human squamous cancer

scientific article published on 01 May 1995

Sustained antiresorptive effects after a single treatment with human recombinant osteoprotegerin (OPG): a pharmacodynamic and pharmacokinetic analysis in rats.

artículo científico publicado en 2003

Systemic administration of acidic fibroblast growth factor (FGF-1) prevents bone loss and increases new bone formation in ovariectomized rats

artículo científico publicado en 1999

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

scientific journal article

Targeting IL-6 and RANKL signaling inhibits prostate cancer growth in bone

artículo científico publicado en 2014

The 18 kDa translocator protein (peripheral benzodiazepine receptor) expression in the bone of normal, osteoprotegerin or low calcium diet treated mice

artículo científico publicado en 2012

The bone remodeling environment is a factor in breast cancer bone metastasis.

artículo científico publicado en 2010

The challenge of continuous exogenous glucocorticoid administration in mice.

artículo científico publicado en 2008

The determination of bone viability: a histochemical method for identification of lactate dehydrogenase activity in osteocytes in fresh calcified and decalcified sections of human bone

artículo científico publicado en 1982

The effect of a single dose of osteoprotegerin in postmenopausal women

artículo científico publicado en 2001

The effect of age on bone composition and viability in the femoral head

artículo científico publicado en 1985

The effect of long-term low-dose diphosphonate treatment on rat bone

artículo científico publicado en 1982

The effect of low-dose cyclical etidronate and calcium on bone mass in early postmenopausal women

artículo científico publicado en 1993

The effect of osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft

artículo científico publicado en 2004

The effectiveness of a soluble calcium preparation as a gut phosphate binder

artículo científico publicado en 1988

The effects of cytokines and growth factors on osteoblastic cells

artículo científico publicado en 1995

The effects of osteoprotegerin on the mechanical properties of rat bone

artículo científico publicado en 2001

The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated

artículo científico publicado en 2000

The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy.

artículo científico publicado en 2005

The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.

artículo científico publicado en 1999

The pathogenesis of idiopathic hypercalciuria: evidence for parathyroid hyperfunction.

artículo científico publicado en 1984

The pathogenesis of osteoarthritis of the hip. Evidence for primary osteocyte death

artículo científico publicado en 1987

The pathogenesis of renal osteodystrophy: role of vitamin D, aluminium, parathyroid hormone, calcium and phosphorus

The ratio of circulating osteoprotegerin to RANKL in early rheumatoid arthritis predicts later joint destruction

scientific article published on 01 June 2006

The receptor activator of nuclear factor-kappaB ligand inhibitor osteoprotegerin is a bone-protective agent in a rat model of chronic renal insufficiency and hyperparathyroidism.

artículo científico publicado en 2005

The role of the bone microenvironment in skeletal metastasis.

artículo científico publicado en 2012

The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.

artículo científico publicado en 2000

The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm

artículo científico publicado en 2017

Theoretical investigation of the role of the RANK-RANKL-OPG system in bone remodeling.

artículo científico publicado en 2009

Therapy insight: the risks and benefits of bisphosphonates for the treatment of tumor-induced bone disease.

artículo científico publicado en 2007

Transgenic disruption of glucocorticoid signaling in mature osteoblasts and osteocytes attenuates K/BxN mouse serum-induced arthritis in vivo.

artículo científico publicado en 2009

Treatment of Paget's disease of bone with a combination of intranasal salmon calcitonin and oral calcium and thiazide

artículo científico publicado en 1991

Treatment of childhood renal osteodystrophy with calcitriol or ergocalciferol

artículo científico publicado en 1985

Treatment of hemodialysis bone disease with 24,25-(OH)2D3 and 1,25-(OH)2D3 alone or in combination

artículo científico publicado en 1985

Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin

artículo científico publicado en 2002

Tumor necrosis factor enhances parathyroid hormone-related protein-induced hypercalcemia and bone resorption without inhibiting bone formation in vivo

artículo científico publicado en 1997

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

artículo científico publicado en 1999

Unique microstructural design of ceramic scaffolds for bone regeneration under load.

artículo científico publicado en 2013

Vitamin D deficiency promotes growth of MCF-7 human breast cancer in a rodent model of osteosclerotic bone metastasis

artículo científico publicado en 2010

Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis

artículo científico publicado en 2010

Vitamin D deficiency promotes prostate cancer growth in bone

artículo científico publicado en 2010

Vitamin D supplements and bone mineral density

Zirconium ions up-regulate the BMP/SMAD signaling pathway and promote the proliferation and differentiation of human osteoblasts

artículo científico publicado en 2015

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

artículo científico publicado en 1998

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