Lista de obras - Sharon Dent - Dominio Público Uruguay

A two-way street: LSD1 regulates chromatin boundary formation in S. pombe and Drosophila.

artículo científico publicado en 2007

AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation

artículo científico publicado en 2014

ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.

artículo científico publicado en 2016

Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas

artículo científico publicado en 2011

Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36.

artículo científico publicado en 2012

Chromatin modifiers and remodellers: regulators of cellular differentiation

artículo científico publicado en 2013

Chromatin signaling to kinetochores: transregulation of Dam1 methylation by histone H2B ubiquitination

artículo científico publicado en 2011

Chromatin: receiver and quarterback for cellular signals

artículo científico publicado en 2013

Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells

artículo científico publicado en 2019

DANPOS: dynamic analysis of nucleosome position and occupancy by sequencing

artículo científico publicado en 2012

Developmental potential of Gcn5(-/-) embryonic stem cells in vivo and in vitro

artículo científico publicado en 2007

Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.

artículo científico publicado en 2017

Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia.

artículo científico publicado en 2015

Expanded complexity of unstable repeat diseases.

artículo científico

Functions of SAGA in development and disease

artículo científico publicado en 2014

Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1.

artículo científico publicado en 2014

Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis

artículo científico publicado en 2014

Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.

artículo científico publicado en 2009

Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model.

artículo científico publicado en 2011

Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2

artículo científico publicado en 2016

Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes

artículo científico publicado en 2018

Histone modifying enzymes and cancer: going beyond histones.

artículo científico publicado en 2005

Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease.

artículo científico publicado en 2012

Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia

artículo científico publicado en 2011

Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene

artículo científico publicado en 2015

KATapulting toward Pluripotency and Cancer

artículo científico publicado en 2016

KATs in cancer: functions and therapies

artículo científico publicado en 2015

Leucine-rich repeat containing 8A (LRRC8A)-dependent volume-regulated anion channel activity is dispensable for T-cell development and function.

artículo científico publicado en 2017

Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos

scientific journal article

Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia

artículo científico publicado en 2016

N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells.

artículo científico publicado en 2012

No Spt6, no nucleosomes, no activator required

artículo científico publicado en 2006

Physical and functional interaction of the yeast corepressor Tup1 with mRNA 5'-triphosphatase.

artículo científico publicado en 2003

Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos.

artículo científico publicado en 2008

Protein-arginine Methyltransferase 1 (PRMT1) Methylates Ash2L, a Shared Component of Mammalian Histone H3K4 Methyltransferase Complexes ⬇️

artículo científico publicado el 8 de abril de 2011

REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ

artículo científico publicado en 2015

Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation

artículo científico publicado en 2003

Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase

artículo científico publicado en 2010

Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation

artículo científico publicado en 2003

Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts.

artículo científico publicado en 2012

Sharon Dent: The unfolding SAGA of chromatin-modifying proteins

artículo científico publicado en 2016

Site-specific loss of acetylation upon phosphorylation of histone H3.

artículo científico publicado en 2002

Stabilization of the promoter nucleosomes in nucleosome-free regions by the yeast Cyc8-Tup1 corepressor.

artículo científico publicado en 2012

TGFβ-activated USP27X deubiquitinase regulates cell migration and chemoresistance via stabilization of Snail1

artículo científico publicado en 2018

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

artículo científico publicado en 2017

Targeting the SAGA and ATAC Transcriptional Coactivator Complexes in MYC-Driven Cancers

artículo científico publicado en 2020

The H2BK123Rgument.

artículo científico publicado en 2009

The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

artículo científico publicado en 2009

The Histone Acetyltransferase Gcn5 Positively Regulates T Cell Activation

artículo científico publicado en 2017

The Lysine Acetyltransferase GCN5 Is Required for iNKT Cell Development through EGR2 Acetylation

artículo científico publicado en 2017

The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation

artículo científico publicado en 2005

The role of chromatin modifiers in normal and malignant hematopoiesis

artículo científico

The role of deubiquitinating enzymes in chromatin regulation.

artículo científico publicado en 2010

Tousled-mediated activation of Aurora B kinase does not require Tousled kinase activity in vivo.

artículo científico publicado en 2008

Transcriptional activation of Myc-induced genes by Gcn5 promotes B-cell lymphomagenesis

artículo científico publicado en 2020

Transcriptional control: an activating role for arginine methylation.

artículo científico publicado en 2002

Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo.

artículo científico publicado en 2003

USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta

scientific article published on 22 February 2019

USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1

artículo científico publicado en 2011

USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B.

artículo científico publicado en 2016

Ubp8 and SAGA regulate Snf1 AMP kinase activity.

artículo científico publicado en 2011

Lista de obras de Sharon Dent

A two-way street: LSD1 regulates chromatin boundary formation in S. pombe and Drosophila.

AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation

ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.

Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas

Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36.

Chromatin modifiers and remodellers: regulators of cellular differentiation

Chromatin signaling to kinetochores: transregulation of Dam1 methylation by histone H2B ubiquitination

Chromatin: receiver and quarterback for cellular signals

Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells

DANPOS: dynamic analysis of nucleosome position and occupancy by sequencing

Developmental potential of Gcn5(-/-) embryonic stem cells in vivo and in vitro

Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.

Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia.

Expanded complexity of unstable repeat diseases.

Functions of SAGA in development and disease

Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1.

Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis

Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.

Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model.

Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2

Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes

Histone modifying enzymes and cancer: going beyond histones.

Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease.

Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia

Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene

KATapulting toward Pluripotency and Cancer

KATs in cancer: functions and therapies

Leucine-rich repeat containing 8A (LRRC8A)-dependent volume-regulated anion channel activity is dispensable for T-cell development and function.

Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos

Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia

N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells.

No Spt6, no nucleosomes, no activator required

Physical and functional interaction of the yeast corepressor Tup1 with mRNA 5'-triphosphatase.

Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos.

Protein-arginine Methyltransferase 1 (PRMT1) Methylates Ash2L, a Shared Component of Mammalian Histone H3K4 Methyltransferase Complexes ⬇️

REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ

Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation

Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase

Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation

Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts.

Sharon Dent: The unfolding SAGA of chromatin-modifying proteins

Site-specific loss of acetylation upon phosphorylation of histone H3.

Stabilization of the promoter nucleosomes in nucleosome-free regions by the yeast Cyc8-Tup1 corepressor.

TGFβ-activated USP27X deubiquitinase regulates cell migration and chemoresistance via stabilization of Snail1

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

Targeting the SAGA and ATAC Transcriptional Coactivator Complexes in MYC-Driven Cancers

The H2BK123Rgument.

The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

The Histone Acetyltransferase Gcn5 Positively Regulates T Cell Activation

The Lysine Acetyltransferase GCN5 Is Required for iNKT Cell Development through EGR2 Acetylation

The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation

The role of chromatin modifiers in normal and malignant hematopoiesis

The role of deubiquitinating enzymes in chromatin regulation.

Tousled-mediated activation of Aurora B kinase does not require Tousled kinase activity in vivo.

Transcriptional activation of Myc-induced genes by Gcn5 promotes B-cell lymphomagenesis

Transcriptional control: an activating role for arginine methylation.

Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo.

USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta

USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1

USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B.

Ubp8 and SAGA regulate Snf1 AMP kinase activity.