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Lista de obras de Dolors Colomer

4-Amino-2-arylamino-6-(2,6-dichlorophenyl)-pyrido[2,3-d]pyrimidin-7-(8H)-ones as BCR kinase inhibitors for B lymphoid malignancies.

artículo científico publicado en 2014

A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact.

artículo científico publicado en 2014

A certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real-time quantitative PCR

artículo científico publicado en 2014

A multicenter evaluation of comprehensive analysis of MLL translocations and fusion gene partners in acute leukemia using the MLL FusionChip device

artículo científico publicado en 2007

A new genetic abnormality leading to TP53 gene deletion in chronic lymphocytic leukaemia

article

A putative "hepitype" in the ATM gene associated with chronic lymphocytic leukemia risk

artículo científico publicado en 2011

A unifying hypothesis for PNMZL and PTFL: morphological variants with a common molecular profile

artículo científico publicado en 2022

Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes

artículo científico publicado en 2003

Activation of mitochondrial apoptotic pathway in mantle cell lymphoma: high sensitivity to mitoxantrone in cases with functional DNA-damage response genes

artículo científico publicado en 2004

Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma

artículo científico publicado en 2017

Acute myeloid leukemia with MLL rearrangements: clinicobiological features, prognostic impact and value of flow cytometry in the detection of residual leukemic cells.

artículo científico publicado en 2003

Acute myeloid leukemia with translocation (8;16)(p11;p13) and MYST3-CREBBP rearrangement harbors a distinctive microRNA signature targeting RET proto-oncogene.

artículo científico publicado en 2012

Allogeneic Stem-Cell Transplantation May Overcome the Adverse Prognosis of UnmutatedVHGene in Patients With Chronic Lymphocytic Leukemia

article published in 2005

An analysis of the kinetics of molecular response during the first trimester of treatment with nilotinib in newly diagnosed chronic myeloid leukemia patients in chronic phase.

artículo científico publicado en 2017

Anaplastic large-cell lymphoma with rapid evolution to leukemic phase

scientific article published on 01 October 1999

Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes

artículo científico publicado en 2013

B cell activation through CD40 and IL4R ligation modulates the response of chronic lymphocytic leukaemia cells to BAFF and APRIL.

artículo científico publicado en 2013

BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells.

artículo científico publicado en 2008

Bendamustine is effective in p53-deficient B-cell neoplasms and requires oxidative stress and caspase-independent signaling

artículo científico publicado en 2008

CD34+-enriched–CD19+-depleted autologous peripheral blood stem cell transplantation for chronic lymphoproliferative disorders

artículo científico publicado en 2002

CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic leukemia.

artículo científico publicado en 2015

CDK4andMDM2Gene Alterations Mainly Occur in Highly Proliferative and Aggressive Mantle Cell Lymphomas with Wild-typeINK4a/ARFLocus

article

CHK2-decreased protein expression and infrequent genetic alterations mainly occur in aggressive types of non-Hodgkin lymphomas

artículo científico publicado en 2002

CXCR5-Mediated Shaping of the Lymphoid Follicle in Chronic Lymphocytic Leukemia

artículo científico publicado en 2014

Cadherin-13, a mediator of calcium-dependent cell-cell adhesion, is silenced by methylation in chronic myeloid leukemia and correlates with pretreatment risk profile and cytogenetic response to interferon alfa

artículo científico publicado en 2003

Cellular Ontogeny and Hierarchy Influence the Reprogramming Efficiency of Human B Cells into Induced Pluripotent Stem Cells.

artículo científico publicado en 2016

Chimeric BCR/ABL gene detected by fluorescence in situ hybridization in three new cases of Philadelphia chromosome-negative chronic myelocytic leukemia.

artículo científico publicado en 2003

Chronic nonspherocytic hemolytic anemia (CNSHA) and glucose 6 phosphate dehydrogenase (G6PD) deficiency in a patient with familial amyloidotic polyneuropathy (FAP)

artículo científico publicado en 1989

Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis

artículo científico publicado en 2014

Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

artículo científico publicado en 2016

Clinical impact of the differentiation profile assessed by immunophenotyping in patients with diffuse large B-cell lymphoma

artículo científico publicado en 2003

Clinical significance of minimal residual disease, as assessed by different techniques, after stem cell transplantation for chronic lymphocytic leukemia.

artículo científico publicado en 2006

Clonal T-cell populations and increased risk for cytotoxic T-cell lymphomas in B-CLL patients: clinicopathologic observations and molecular analysis

artículo científico publicado en 2004

Clonal evolution in chronic lymphocytic leukemia: analysis of correlations with IGHV mutational status, NOTCH1 mutations and clinical significance

artículo científico publicado en 2013

Coding sequence and intron-exon junctions of the c-myb gene are intact in the chronic phase and blast crisis stages of chronic myeloid leukemia patients.

artículo científico publicado en 2006

Combined analysis of levels of serum B-cell activating factor and a proliferation-inducing ligand as predictor of disease progression in patients with chronic lymphocytic leukemia.

artículo científico publicado en 2011

Complement-mediated cell death induced by rituximab in B-cell lymphoproliferative disorders is mediated in vitro by a caspase-independent mechanism involving the generation of reactive oxygen species

artículo científico publicado en 2001

Congenital 6-phosphogluconate dehydrogenase (6PGD) deficiency associated with chronic hemolytic anemia in a Spanish family

scientific article published on 01 December 1996

Correlation between genetic polymorphisms of the hOCT1 and MDR1 genes and the response to imatinib in patients newly diagnosed with chronic-phase chronic myeloid leukemia.

artículo científico publicado en 2010

Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma

artículo científico publicado en 2012

Cytotoxic effects of B lymphocytes mediated by reactive oxygen species

artículo científico publicado en 2004

Detection of chromothripsis-like patterns with a custom array platform for chronic lymphocytic leukemia.

artículo científico publicado en 2015

Development and evaluation of a secondary reference panel for BCR-ABL1 quantification on the International Scale

scientific article published on 25 April 2016

Different clinical value of minimal residual disease after autologous and allogeneic stem cell transplantation for chronic lymphocytic leukemia

artículo científico publicado en 2002

Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations.

artículo científico publicado en 2012

Diffuse large B-cell lymphoma: clinical and biological characterization and outcome according to the nodal or extranodal primary origin

artículo científico publicado en 2005

Disruption of follicular dendritic cells-follicular lymphoma cross-talk by the pan-PI3K inhibitor BKM120 (Buparlisib).

artículo científico publicado en 2014

Dual targeting of MCL1 and NOXA as effective strategy for treatment of mantle cell lymphoma

artículo científico publicado en 2017

Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

artículo científico publicado en 2021

Early intervention during imatinib therapy in patients with newly diagnosed chronic-phase chronic myeloid leukemia: a study of the Spanish PETHEMA group

artículo científico publicado en 2010

Effect of TPA on fructose 2,6-bisphosphate levels and protein kinase C activity in B-chronic lymphocytic leukemia (B-CLL)

artículo científico publicado en 1991

Efficacy of lenalidomide in a patient with myelodysplastic syndrome with isolated del(5q) and JAK2V617F mutation.

artículo científico publicado en 2011

Elevated production of interleukin-6 is associated with a lower incidence of disease-related ischemic events in patients with giant-cell arteritis: angiogenic activity of interleukin-6 as a potential protective mechanism.

artículo científico publicado en 2003

Enhancement of fludarabine sensitivity by all-trans-retinoic acid in chronic lymphocytic leukemia cells

artículo científico publicado en 2011

Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia.

artículo científico publicado en 2012

Epstein-Barr virus negative clonal plasma cell proliferations and lymphomas in peripheral T-cell lymphomas: a phenomenon with distinctive clinicopathologic features

artículo científico publicado en 2007

Equilibrative nucleoside transporter-2 (hENT2) protein expression correlates with ex vivo sensitivity to fludarabine in chronic lymphocytic leukemia (CLL) cells

artículo científico publicado en 2005

Erythrocyte Fructose 2,6-Bisphosphate Content in Congenital Hemolytic Anemias

artículo científico publicado en 1991

Essential thrombocythemia in young individuals: frequency and risk factors for vascular events and evolution to myelofibrosis in 126 patients

artículo científico publicado en 2007

Establishment and validation of analytical reference panels for the standardization of quantitative BCR-ABL1 measurements on the international scale.

artículo científico publicado en 2013

Establishment of the first World Health Organization International Genetic Reference Panel for quantitation of BCR-ABL mRNA.

artículo científico publicado en 2010

Evaluation of a novel multiplex RT-qPCR assay for the quantification of leukemia-associated BCR-ABL1 translocation.

artículo científico publicado en 2015

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

artículo científico publicado en 2011

Expression and mutational analyses of KIT and PDGFR-alpha in sarcomatoid renal cell carcinoma.

artículo científico publicado en 2009

Favorable outcome of patients with acute myeloid leukemia harboring a low-allelic burden FLT3-ITD mutation and concomitant NPM1 mutation: relevance to post-remission therapy

artículo científico publicado en 2013

Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2003

Fludarabine, cyclophosphamide and mitoxantrone in the treatment of resistant or relapsed chronic lymphocytic leukaemia

artículo científico publicado en 2002

Fluorescent nucleoside derivatives as a tool for the detection of concentrative nucleoside transporter activity using confocal microscopy and flow cytometry.

artículo científico publicado en 2015

Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM.

artículo científico publicado en 2009

Gene expression profile and genomic changes in disease progression of early-stage chronic lymphocytic leukemia

article

Gene expression profiling of acute myeloid leukemia with translocation t(8;16)(p11;p13) and MYST3-CREBBP rearrangement reveals a distinctive signature with a specific pattern of HOX gene expression.

artículo científico publicado en 2006

Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics

artículo científico publicado en 2007

Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia

artículo científico publicado en 2008

Genomic and Gene Expression Profiling Defines Indolent Forms of Mantle Cell Lymphoma

article

Genomic complexity and IGHV mutational status are key predictors of outcome of chronic lymphocytic leukemia patients with TP53 disruption

artículo científico publicado en 2014

Genomic imbalances and patterns of karyotypic variability in mantle-cell lymphoma cell lines

artículo científico publicado en 2006

Genomic p16 abnormalities in the progression of chronic myeloid leukemia into blast crisis

artículo científico publicado en 2003

Hematopoietic stem cell transplantation in chronic lymphocytic leukemia: A report of 12 patients from a single institution

artículo científico publicado en 1998

Heterozygous pyruvate kinase deficiency and severe hemolytic anemia in a pregnant woman with concomitant, glucose-6-phosphate dehydrogenase deficiency.

artículo científico publicado en 1991

High clinical and molecular response rates with fludarabine, cyclophosphamide and mitoxantrone in previously untreated patients with advanced stage follicular lymphoma.

artículo científico publicado en 2008

High levels of chromosomal imbalances in typical and small-cell variants of T-cell prolymphocytic leukemia

artículo científico publicado en 2003

Human organic cation transporter 1 (hOCT1) as a mediator of bendamustine uptake and cytotoxicity in chronic lymphocytic leukemia (CLL) cells

artículo científico publicado en 2015

Identification of TIGAR in the equilibrative nucleoside transporter 2-mediated response to fludarabine in chronic lymphocytic leukemia cells

artículo científico publicado en 2008

Imatinib dose reduction in patients with chronic myeloid leukemia in sustained deep molecular response

artículo científico publicado en 2016

Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms

artículo científico publicado en 2005

Impact of genotype on leukaemic transformation in polycythaemia vera and essential thrombocythaemia

artículo científico publicado en 2017

Impact of the functional CD5 polymorphism A471V on the response of chronic lymphocytic leukaemia to conventional chemotherapy regimens

artículo científico publicado en 2016

Improved classification of leukemic B-cell lymphoproliferative disorders using a transcriptional and genetic classifier.

artículo científico publicado en 2017

In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts

artículo científico publicado en 2010

In vivo intratumoral Epstein-Barr virus replication is associated with XBP1 activation and early-onset post-transplant lymphoproliferative disorders with prognostic implications.

artículo científico publicado en 2014

Incidence and clinical significance of bcl-2/IgH rearrangements in follicular lymphoma.

artículo científico publicado en 2003

Increased incidence of acute myeloid leukemia after liver transplantation? Description of three new cases and review of the literature

artículo científico publicado en 2004

Increased platelet, leukocyte, and coagulation activation in primary myelofibrosis

artículo científico publicado en 2007

Independent origin of single and double mutations in the human glucose 6-phosphate dehydrogenase gene

artículo científico publicado en 1996

International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia.

artículo científico publicado en 2007

Involvement of protein kinase C and phosphatidylinositol 3-kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells.

artículo científico publicado en 2002

Laboratory recommendations for scoring deep molecular responses following treatment for chronic myeloid leukemia.

artículo científico publicado en 2015

Lack of association of CYP3A4-V polymorphism with the risk of treatment-related leukemia

artículo científico publicado en 2005

Lack of methylthioadenosine phosphorylase expression in mantle cell lymphoma is associated with shorter survival: implications for a potential targeted therapy

artículo científico publicado en 2006

Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.

artículo científico publicado en 2013

Long-term safety and outcome of fludarabine, cyclophosphamide and mitoxantrone (FCM) regimen in previously untreated patients with advanced follicular lymphoma: 12 years follow-up of a phase 2 trial

artículo científico publicado en 2017

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

artículo científico publicado en 2005

MYD88 L265P Mutations, But No Other Variants, Identify a Subpopulation of DLBCL Patients of Activated B-cell Origin, Extranodal Involvement, and Poor Outcome

artículo científico publicado en 2016

Mantle cell lymphoma in Taiwan: Clinicopathological and molecular study of 21 cases including one cyclin D1-negative tumor expressing cyclin D2

Mechanism of action and resistance to monoclonal antibody therapy

artículo científico publicado en 2003

MicroRNA expression, chromosomal alterations, and immunoglobulin variable heavy chain hypermutations in Mantle cell lymphomas.

artículo científico publicado en 2009

Mitoxantrone, a topoisomerase II inhibitor, induces apoptosis of B-chronic lymphocytic leukaemia cells

artículo científico publicado en 1998

Molecular biology in acute leukemia

artículo científico publicado en 2006

Molecular lymph node staging in bladder urothelial carcinoma: impact on survival.

artículo científico publicado en 2008

Molecular pathogenesis of mantle cell lymphoma

artículo científico publicado en 2012

Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biologic and clinical features

artículo científico publicado en 2012

Monosomy 7 with severe myelodysplasia developing during imatinib treatment of Philadelphia-positive chronic myeloid leukemia: Two cases with a different outcome

artículo científico publicado en 2007

Multiple recurrent chromosomal breakpoints in mantle cell lymphoma revealed by a combination of molecular cytogenetic techniques

artículo científico publicado en 2008

Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome

scientific article published on 29 April 2014

NF-kappaB as a therapeutic target in chronic lymphocytic leukemia

scientific article published on March 2010

NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome.

artículo científico publicado en 2012

NOTCH1 mutations in chronic lymphocytic leukemia with trisomy 12

NOTCH1, TP53, and MAP2K1 Mutations in Splenic Diffuse Red Pulp Small B-cell Lymphoma Are Associated With Progressive Disease

artículo científico publicado en 2015

Non-coding recurrent mutations in chronic lymphocytic leukaemia

artículo científico publicado en 2015

Non-nodal type of mantle cell lymphoma is a specific biological and clinical subgroup of the disease

artículo científico publicado en 2012

Nondeletional α-thalassemia: First description of αHphα and αNcoα mutations in a Spanish population

artículo científico publicado en 1996

Nonhepatosplenic γδ T-cell lymphomas represent a spectrum of aggressive cytotoxic T-cell lymphomas with a mainly extranodal presentation

artículo científico publicado en 2011

Notch1 signaling in NOTCH1-mutated mantle cell lymphoma depends on Delta-Like ligand 4 and is a potential target for specific antibody therapy

artículo científico publicado en 2019

Outcome of patients with acute promyelocytic leukemia failing to front-line treatment with all-trans retinoic acid and anthracycline-based chemotherapy (PETHEMA protocols LPA96 and LPA99): benefit of an early intervention

artículo científico publicado en 2007

Plasma cell and terminal B-cell differentiation in mantle cell lymphoma mainly occur in the SOX11-negative subtype

Platelet turnover, coagulation factors, and soluble markers of platelet and endothelial activation in essential thrombocythemia: Relationship with thrombosis occurrence andJAK2 V617F allele burden

artículo científico publicado en 2009

Prodigiosin induces apoptosis of B and T cells from B-cell chronic lymphocytic leukemia.

artículo científico publicado en 2003

Profile of polymorphisms of drug-metabolising enzymes and the risk of therapy-related leukaemia

artículo científico publicado en 2007

Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy

artículo científico publicado en 2011

Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia

artículo científico publicado en 2005

Pyrimidine 5′-Nucleotidase Acquired Deficiency in Beta-Thalassaemia: Involvement of Enzyme-SH Groups in the Inactivation Process

artículo científico publicado en 1990

Quantitative assessment of PML-RARa and BCR-ABL by two real-time PCR instruments: multiinstitutional laboratory trial.

artículo científico publicado en 2004

Rapid Diagnosis of Acute Promyelocytic Leukemia by Analyzing the Immunocytochemical Pattern of the PML Protein With the Monoclonal Antibody PG-M3

artículo científico publicado en 2000

Recurrent mutations of NOTCH genes in follicular lymphoma identify a distinctive subset of tumours.

artículo científico publicado en 2014

Refining the diagnosis and prognostic categorization of acute myeloid leukemia patients with an integrated use of cytogenetic and molecular studies

artículo científico publicado en 2012

Relationship between the 46/1 haplotype of the JAK2 gene and the JAK2 mutational status and allele burden, the initial findings, and the survival of patients with myelofibrosis.

artículo científico publicado en 2013

Risk-adapted treatment of acute promyelocytic leukemia with all-trans retinoic acid and anthracycline monochemotherapy: long-term outcome of the LPA 99 multicenter study by the PETHEMA Group.

artículo científico publicado en 2008

Role of calreticulin mutations in the aetiological diagnosis of splanchnic vein thrombosis

artículo científico publicado en 2014

SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype.

artículo científico publicado en 2009

SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma

artículo científico publicado en 2013

Selective BTK inhibition improves bendamustine therapy response and normalizes immune effector functions in chronic lymphocytic leukemia

artículo científico publicado en 2019

Selective testing for calreticulin gene mutations in patients with splanchnic vein thrombosis: A prospective cohort study

artículo científico publicado en 2017

Serial quantification of lymphoid and myeloid mixed chimerism using multiplex PCR amplification of short tandem repeat-markers predicts graft rejection and relapse, respectively, after allogeneic transplantation of CD34+ selected cells from peripher

artículo científico publicado en 2003

Simultaneous diagnosis of hairy cell leukemia and chronic lymphocytic leukemia/small lymphocytic lymphoma: a frequent association?

artículo científico publicado en 2002

Sorafenib inhibits cell migration and stroma-mediated bortezomib resistance by interfering B-cell receptor signaling and protein translation in mantle cell lymphoma

artículo científico publicado en 2012

Sorafenib targets BCR kinases and blocks migratory and microenvironmental survival signals in CLL cells.

artículo científico publicado en 2011

Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells

scientific article published on 15 October 2019

Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2002

Stem cell transplantation for chronic lymphocytic leukemia: different outcome after autologous and allogeneic transplantation and correlation with minimal residual disease status.

artículo científico publicado en 2001

Studies of complex Ph translocations in cases with chronic myelogenous leukemia and one with acute lymphoblastic leukemia

Study of hematopoietic chimerism following allogeneic peripheral blood stem cell transplantation using PCR amplification of short tandem repeats

artículo científico publicado en 1996

Surface adenosine deaminase. A novel B-cell marker in chronic lymphocytic leukemia

artículo científico publicado en 1995

Survival after progression in patients with follicular lymphoma: analysis of prognostic factors

artículo científico publicado en 2002

Survivin expression in the progression of chronic myeloid leukemia: a sequential study in 16 patients.

artículo científico publicado en 2005

Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma

artículo científico publicado en 2014

Targeting IRAK4 disrupts inflammatory pathways and delays tumor development in chronic lymphocytic leukemia

scientific article published on 13 June 2019

The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak

scientific article published on 16 January 2007

The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia

artículo científico publicado en 2016

The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma

artículo científico publicado en 2014

The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78

scientific article published on 24 November 2010

The Human CD38 Monoclonal Antibody Daratumumab Shows Antitumor Activity and Hampers Leukemia-Microenvironment Interactions in Chronic Lymphocytic Leukemia.

artículo científico publicado en 2016

The eNOS cofactor tetrahydrobiopterin improves endothelial dysfunction in livers of rats with CCl4 cirrhosis

artículo científico publicado en 2006

The expression of the endoplasmic reticulum stress sensor BiP/GRP78 predicts response to chemotherapy and determines the efficacy of proteasome inhibitors in diffuse large b-cell lymphoma

artículo científico publicado en 2011

The phosphatidylinositol-3-kinase inhibitor NVP-BKM120 overcomes resistance signals derived from microenvironment by regulating the Akt/FoxO3a/Bim axis in chronic lymphocytic leukemia cells

artículo científico publicado en 2013

The potential effect of gender in combination with common genetic polymorphisms of drug-metabolizing enzymes on the risk of developing acute leukemia

artículo científico publicado en 2007

The prognostic impact of minimal residual disease in patients with chronic lymphocytic leukemia requiring first-line therapy

artículo científico publicado en 2014

The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status

artículo científico publicado en 2005

The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells

artículo científico publicado en 2014

Tissue production of pro-inflammatory cytokines (IL-1beta, TNFalpha and IL-6) correlates with the intensity of the systemic inflammatory response and with corticosteroid requirements in giant-cell arteritis

artículo científico publicado en 2003

Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia

artículo científico publicado en 2013

Translocation of nucleoside analogs across the plasma membrane in hematologic malignancies

artículo científico

Type I MOZ/CBP (MYST3/CREBBP) is the most common chimeric transcript in acute myeloid leukemia with t(8;16)(p11;p13) translocation

artículo científico publicado en 2004

Tyrosinase mRNA in Blood of Patients With Melanoma Treated With Adjuvant Interferon

artículo científico publicado en 2002

Unlocking New Therapeutic Targets and Resistance Mechanisms in Mantle Cell Lymphoma

Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters

artículo científico publicado en 2011

ZAP-70 Expression in Normal Pro/Pre B Cells, Mature B Cells, and in B-Cell Acute Lymphoblastic Leukemia

artículo científico publicado en 2006

ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

artículo científico publicado en 2003

p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541.

artículo científico publicado en 2009

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