Lista de obras - Franca Zanardi - Dominio Público Uruguay

3-Alkenyl-2-silyloxyindoles in vinylogous Mannich reactions: synthesis of aminated indole-based scaffolds and products

artículo científico publicado en 2014

4-Aminoproline-based arginine-glycine-aspartate integrin binders with exposed ligation points: practical in-solution synthesis, conjugation and binding affinity evaluation.

artículo científico publicado en 2009

A one-pot entry to a novel 3-H-benzo[d]pyrazolo[1,5-b]isothiazole ring system

artículo científico publicado en 2006

Acetaldehyde Silyl Enol Ethers in Enantioselective Mukaiyama Aldol Reactions: Enzyme-Like Organocatalysis in Action

artículo científico publicado en 2019

Asymmetric total synthesis of 1-deoxy-7,8-di-epi-castanospermine.

artículo científico publicado en 2010

Bifunctional cinchona alkaloid/thiourea catalyzes direct and enantioselective vinylogous Michael addition of 3-alkylidene oxindoles to nitroolefins

artículo científico publicado en 2012

Catalytic, asymmetric hypervinylogous Mukaiyama aldol reactions of extended furan-based silyl enolates

scientific article published on 11 August 2011

Design, synthesis, and biological evaluation of novel cRGD-paclitaxel conjugates for integrin-assisted drug delivery.

artículo científico publicado en 2012

Diastereo- and enantioselective catalytic vinylogous Mukaiyama-Mannich reactions of pyrrole-based silyl dienolates with alkyl-substituted aldehydes

scientific article published on 22 November 2011

Diastereoselective synthesis of 4,5'-bis-proline compounds via reductive dimerization of N-acyloxyiminium ions

scientific article published on 31 January 2007

Discovery of subnanomolar arginine-glycine-aspartate-based alphaVbeta3/alphaVbeta5 integrin binders embedding 4-aminoproline residues.

artículo científico publicado en 2008

Efficacy of a Selective Binder of αVβ3 Integrin Linked to the Tyrosine Kinase Inhibitor Sunitinib in Ovarian Carcinoma Preclinical Models

artículo científico publicado en 2019

Enantioselective total synthesis of (1R,3S,4R,5R)-1-amino-4,5-dihydroxycyclopentane-1,3-dicarboxylic acid. A full-aldol access to carbaketose derivatives

artículo científico publicado en 2004

Enhancement of the uptake and cytotoxic activity of doxorubicin in cancer cells by novel cRGD-semipeptide-anchoring liposomes.

artículo científico publicado en 2014

Expeditious syntheses of sugar-modified nucleosides and collections thereof exploiting furan-, pyrrole-, and thiophene-based siloxy dienes

scientific article published on 01 January 1997

Exploiting the Distal Reactivity of Indolyl Methylenemalononitriles: An Asymmetric Organocatalyzed [4+2] Cycloaddition with Enals Enables the Assembly of Elusive Dihydrocarbazoles

artículo científico publicado en 2016

Exploring the vinylogous reactivity of cyclohexenylidene malononitriles: switchable regioselectivity in the organocatalytic asymmetric addition to enals giving highly enantioenriched carbabicyclic structures

artículo científico publicado en 2014

Grafting aminocyclopentane carboxylic acids onto the RGD tripeptide sequence generates low nanomolar alphaVbeta3/alphaVbeta5 integrin dual binders.

artículo científico publicado en 2005

Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines

artículo científico publicado en 2015

New Developments of the Principle of Vinylogy as Applied to π-Extended Enolate-Type Donor Systems

artículo científico publicado en 2020

New enantioselective entry to cycloheptane amino acid polyols

artículo científico publicado en 2006

Organocatalytic, Asymmetric Eliminative [4+2] Cycloaddition of Allylidene Malononitriles with Enals: Rapid Entry to Cyclohexadiene-Embedding Linear and Angular Polycycles.

artículo científico publicado en 2015

Parallel, Stereoselective Syntheses of both Enantiomers of Muricatacin and Their Sulfur and Nitrogen Relatives Using the Silyloxy Diene-Based Methodology

scientific article published on 01 June 1997

Pushing the boundaries of vinylogous reactivity: catalytic enantioselective mukaiyama aldol reactions of highly unsaturated 2-silyloxyindoles

artículo científico publicado en 2015

Streamlined, asymmetric synthesis of 8,4'-oxyneolignans

scientific article published on 01 October 2006

Synthesis of Novel c(AmpRGD)-Sunitinib Dual Conjugates as Molecular Tools Targeting the αvβ3 Integrin/VEGFR2 Couple and Impairing Tumor-Associated Angiogenesis

artículo científico publicado en 2016

Synthesis, structure and inhibitory activity of a stereoisomer of oseltamivir carboxylate

artículo científico publicado en 2014

Synthetic and analytical strategies for the quantification of phenyl-γ-valerolactone conjugated metabolites in human urine

artículo científico publicado en 2017

Targeting alphavbeta3 integrin: design and applications of mono- and multifunctional RGD-based peptides and semipeptides

scientific article published on January 2010

The Vinylogous Aldol Reaction: A Valuable, Yet Understated Carbon−Carbon Bond-Forming Maneuver

artículo científico publicado en 2000

The utility of furan-, pyrrole-, and thiophene-based 2-silyloxy dienes as demonstrated by modular synthesis of annonaceous acetogenin core units and their pyrrolidine and thiolane analogues

artículo científico publicado en 2000

The vinylogous aldol and related addition reactions: ten years of progress

scientific article published on 24 March 2011

Uncatalyzed, diastereoselective vinylogous Mukaiyama aldol reactions on aqueous media: pyrrole vs furan 2-silyloxy dienes.

artículo científico publicado en 2010

Variable strategy toward carbasugars and relatives. 1. Stereocontrolled synthesis of pseudo-beta-D-gulopyranose, pseudo-beta-D-xylofuranose, (pseudo-beta-D-gulopyranosyl)amine, and (pseudo-beta-D-xylofuranosyl)amine

artículo científico publicado en 2000

Variable strategy toward carbasugars and relatives. 2. Diversity-based synthesis of beta-D-xylo, beta-D-ribo, beta-L-arabino, and beta-L-lyxo 4a-carbafuranoses and (4a-carbafuranosyl)thiols

artículo científico publicado en 2001

Variable strategy toward carbasugars and relatives. 4. Viable access to (4a-carbapentofuranosyl)amines, (5a-carbahexopyranosyl)amines, and amino acids thereof

artículo científico publicado en 2002

Variable strategy toward carbasugars and relatives. 5.(1) Focus on preparation of chiral nonracemic medium-sized carbocycles.

artículo científico publicado en 2003

Variable strategy toward carbasugars and relatives. 6. Diastereoselective synthesis of 2-deoxy-2-amino-5a-carba-beta-L-mannopyranuronic acid and 2-deoxy-2-amino-5a-carba-beta-L-mannopyranose

artículo científico publicado en 2004

Vicarious silylative Mukaiyama aldol reaction: a vinylogous extension.

artículo científico publicado en 2008

anti-Selective, catalytic asymmetric vinylogous Mukaiyama Mannich reactions of pyrrole-based silyl dienolates with N-aryl aldimines

artículo científico publicado en 2011

Lista de obras de Franca Zanardi

3-Alkenyl-2-silyloxyindoles in vinylogous Mannich reactions: synthesis of aminated indole-based scaffolds and products

4-Aminoproline-based arginine-glycine-aspartate integrin binders with exposed ligation points: practical in-solution synthesis, conjugation and binding affinity evaluation.

A one-pot entry to a novel 3-H-benzo[d]pyrazolo[1,5-b]isothiazole ring system

Acetaldehyde Silyl Enol Ethers in Enantioselective Mukaiyama Aldol Reactions: Enzyme-Like Organocatalysis in Action

Asymmetric total synthesis of 1-deoxy-7,8-di-epi-castanospermine.

Bifunctional cinchona alkaloid/thiourea catalyzes direct and enantioselective vinylogous Michael addition of 3-alkylidene oxindoles to nitroolefins

Catalytic, asymmetric hypervinylogous Mukaiyama aldol reactions of extended furan-based silyl enolates

Design, synthesis, and biological evaluation of novel cRGD-paclitaxel conjugates for integrin-assisted drug delivery.

Diastereo- and enantioselective catalytic vinylogous Mukaiyama-Mannich reactions of pyrrole-based silyl dienolates with alkyl-substituted aldehydes

Diastereoselective synthesis of 4,5'-bis-proline compounds via reductive dimerization of N-acyloxyiminium ions

Discovery of subnanomolar arginine-glycine-aspartate-based alphaVbeta3/alphaVbeta5 integrin binders embedding 4-aminoproline residues.

Efficacy of a Selective Binder of αVβ3 Integrin Linked to the Tyrosine Kinase Inhibitor Sunitinib in Ovarian Carcinoma Preclinical Models

Enantioselective total synthesis of (1R,3S,4R,5R)-1-amino-4,5-dihydroxycyclopentane-1,3-dicarboxylic acid. A full-aldol access to carbaketose derivatives

Enhancement of the uptake and cytotoxic activity of doxorubicin in cancer cells by novel cRGD-semipeptide-anchoring liposomes.

Expeditious syntheses of sugar-modified nucleosides and collections thereof exploiting furan-, pyrrole-, and thiophene-based siloxy dienes

Exploiting the Distal Reactivity of Indolyl Methylenemalononitriles: An Asymmetric Organocatalyzed [4+2] Cycloaddition with Enals Enables the Assembly of Elusive Dihydrocarbazoles

Exploring the vinylogous reactivity of cyclohexenylidene malononitriles: switchable regioselectivity in the organocatalytic asymmetric addition to enals giving highly enantioenriched carbabicyclic structures

Grafting aminocyclopentane carboxylic acids onto the RGD tripeptide sequence generates low nanomolar alphaVbeta3/alphaVbeta5 integrin dual binders.

Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines

New Developments of the Principle of Vinylogy as Applied to π-Extended Enolate-Type Donor Systems

New enantioselective entry to cycloheptane amino acid polyols

Organocatalytic, Asymmetric Eliminative [4+2] Cycloaddition of Allylidene Malononitriles with Enals: Rapid Entry to Cyclohexadiene-Embedding Linear and Angular Polycycles.

Parallel, Stereoselective Syntheses of both Enantiomers of Muricatacin and Their Sulfur and Nitrogen Relatives Using the Silyloxy Diene-Based Methodology

Pushing the boundaries of vinylogous reactivity: catalytic enantioselective mukaiyama aldol reactions of highly unsaturated 2-silyloxyindoles

Streamlined, asymmetric synthesis of 8,4'-oxyneolignans

Synthesis of Novel c(AmpRGD)-Sunitinib Dual Conjugates as Molecular Tools Targeting the αvβ3 Integrin/VEGFR2 Couple and Impairing Tumor-Associated Angiogenesis

Synthesis, structure and inhibitory activity of a stereoisomer of oseltamivir carboxylate

Synthetic and analytical strategies for the quantification of phenyl-γ-valerolactone conjugated metabolites in human urine

Targeting alphavbeta3 integrin: design and applications of mono- and multifunctional RGD-based peptides and semipeptides

The Vinylogous Aldol Reaction: A Valuable, Yet Understated Carbon−Carbon Bond-Forming Maneuver

The utility of furan-, pyrrole-, and thiophene-based 2-silyloxy dienes as demonstrated by modular synthesis of annonaceous acetogenin core units and their pyrrolidine and thiolane analogues

The vinylogous aldol and related addition reactions: ten years of progress

Uncatalyzed, diastereoselective vinylogous Mukaiyama aldol reactions on aqueous media: pyrrole vs furan 2-silyloxy dienes.

Variable strategy toward carbasugars and relatives. 1. Stereocontrolled synthesis of pseudo-beta-D-gulopyranose, pseudo-beta-D-xylofuranose, (pseudo-beta-D-gulopyranosyl)amine, and (pseudo-beta-D-xylofuranosyl)amine

Variable strategy toward carbasugars and relatives. 2. Diversity-based synthesis of beta-D-xylo, beta-D-ribo, beta-L-arabino, and beta-L-lyxo 4a-carbafuranoses and (4a-carbafuranosyl)thiols

Variable strategy toward carbasugars and relatives. 4. Viable access to (4a-carbapentofuranosyl)amines, (5a-carbahexopyranosyl)amines, and amino acids thereof

Variable strategy toward carbasugars and relatives. 5.(1) Focus on preparation of chiral nonracemic medium-sized carbocycles.

Variable strategy toward carbasugars and relatives. 6. Diastereoselective synthesis of 2-deoxy-2-amino-5a-carba-beta-L-mannopyranuronic acid and 2-deoxy-2-amino-5a-carba-beta-L-mannopyranose

Vicarious silylative Mukaiyama aldol reaction: a vinylogous extension.

anti-Selective, catalytic asymmetric vinylogous Mukaiyama Mannich reactions of pyrrole-based silyl dienolates with N-aryl aldimines