Lista de obras - Marcos R M Fontes - Dominio Público Uruguay

A calmodulin-like protein (LCALA) is a new Leishmania amazonensis candidate for telomere end-binding protein.

artículo científico publicado en 2017

A novel synthetic quinolinone inhibitor presents proteolytic and hemorrhagic inhibitory activities against snake venom metalloproteases.

artículo científico publicado en 2015

A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms

artículo científico

Alkylation of histidine residues of Bothrops jararacussu venom proteins and isolated phospholipases A2: a biotechnological tool to improve the production of antibodies

artículo científico publicado en 2014

An evaluation of 3-rhamnosylquercetin, a glycosylated form of quercetin, against the myotoxic and edematogenic effects of sPLA 2 from Crotalus durissus terrificus

artículo científico publicado en 2014

Analysis of Bothrops jararacussu venomous gland transcriptome focusing on structural and functional aspects: I--gene expression profile of highly expressed phospholipases A2.

artículo científico publicado en 2004

Anti-Metalloprotease P-I Single-Domain Antibodies: Tools for Next-Generation Snakebite Antivenoms

artículo científico publicado en 2022

Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

artículo científico publicado en 2020

Biochemical, functional, structural and phylogenetic studies on Intercro, a new isoform phospholipase A2 from Crotalus durissus terrificus snake venom.

artículo científico publicado en 2013

Biochemical, pharmacological and structural characterization of BmooMP-I, a new P-I metalloproteinase from Bothrops moojeni venom

artículo científico publicado en 2020

Biophysical characterization of interactions involving importin-alpha during nuclear import

artículo científico publicado en 2001

Biophysical studies suggest a new structural arrangement of crotoxin and provide insights into its toxic mechanism.

artículo científico publicado en 2017

BmajPLA2-II, a basic Lys49-phospholipase A2 homologue from Bothrops marajoensis snake venom with parasiticidal potential.

artículo científico publicado en 2017

Bothrops moojeni myotoxin-II, a Lys49-phospholipase A2 homologue: an example of function versatility of snake venom proteins

artículo científico publicado en 2006

Cloning and identification of a complete cDNA coding for a bactericidal and antitumoral acidic phospholipase A2 from Bothrops jararacussu venom

artículo científico publicado en 2004

Comparative structural studies on Lys49-phospholipases A(2) from Bothrops genus reveal their myotoxic site

artículo científico publicado en 2009

Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s

artículo científico publicado en 2010

Crotoxin: novel activities for a classic beta-neurotoxin.

artículo científico publicado en 2010

Crystal structure of a myotoxic Asp49-phospholipase A2 with low catalytic activity: Insights into Ca2+-independent catalytic mechanism

artículo científico publicado en 2008

Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative "myotoxic cluster".

artículo científico publicado en 2016

Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A2: quaternary structure and inhibition mechanism insights ⬇️

artículo científico publicado el 21 de noviembre de 2003

Crystallization and preliminary X-ray crystallographic analysis of importin-α from Neurospora crassa.

artículo científico publicado en 2014

Crystallization and preliminary X-ray diffraction analysis of a Lys49-phospholipase A2complexed with caffeic acid, a molecule with inhibitory properties against snake venoms ⬇️

artículo científico publicado el 22 de enero de 2011

Crystallization and preliminary X-ray diffraction analysis of a myotoxic Lys49-PLA2 from Bothrops jararacussu venom complexed with p-bromophenacyl bromide.

artículo científico publicado en 2006

Crystallization and preliminary X-ray diffraction analysis of a myotoxic phospholipase A(2) homologue from Bothrops neuwiedi pauloensis venom

artículo científico publicado en 1999

Crystallization and preliminary X-ray diffraction analysis of an acidic phospholipase A(2) complexed with p-bromophenacyl bromide and alpha-tocopherol inhibitors at 1.9- and 1.45-A resolution

artículo científico publicado en 2004

Crystallization and preliminary X-ray diffraction analysis of crotoxin B from Crotalus durissus collilineatus venom

artículo científico publicado en 2009

Crystallization and preliminary X-ray diffraction analysis of importin-alpha complexed with NLS peptidomimetics

artículo científico publicado en 2005

Crystallization and preliminary X-ray diffraction analysis of three myotoxic phospholipases A2 from Bothrops brazili venom.

artículo científico publicado en 2012

Crystallization and preliminary X-ray diffraction studies of BmooPLA2-I, a platelet-aggregation inhibitor and hypotensive phospholipase A2 from Bothrops moojeni venom.

artículo científico publicado en 2011

DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway

artículo científico publicado en 2017

Functional and structural studies of a Phospholipase A2-like protein complexed to zinc ions: Insights on its myotoxicity and inhibition mechanism.

artículo científico publicado en 2016

Geographic variations in the composition of myotoxins from Bothrops neuwiedi snake venoms: biochemical characterization and biological activity

scientific article published on 01 November 1998

Identification of continuous interaction sites in PLA(2)-based protein complexes by peptide arrays

artículo científico publicado en 2009

In Vivo genotoxicity of a commercial C.I. Disperse Red 1 dye

artículo científico publicado en 2018

In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum-infected red blood cells

artículo científico publicado en 2010

Influence of quaternary conformation on the biological activities of the Asp49-phospholipases A2s from snake venoms

scientific article published on 01 January 2009

Initiating Structural Studies Of Lys49-Pla2 Homologues Complexed With An Anionic Detergent, A Fatty Acid And A Natural Lipid ⬇️

artículo científico publicado el 1 de octubre de 2003

Insights on the structure of native CNF, an endogenous phospholipase A2 inhibitor from Crotalus durissus terrificus, the South American rattlesnake

artículo científico publicado en 2014

Isolation and biochemical characterization of a γ-type phospholipase A2 inhibitor from Crotalus durissus collilineatus snake serum.

artículo científico publicado en 2014

Molecular Components of the Neurospora crassa pH Signaling Pathway and Their Regulation by pH and the PAC-3 Transcription Factor

artículo científico publicado en 2016

Molecular and functional characterization of a new non-hemorrhagic metalloprotease from Bothrops jararacussu snake venom with antiplatelet activity

scientific article published on 22 October 2007

Molecular approaches for structural characterization of Bothrops L-amino acid oxidases with antiprotozoal activity: cDNA cloning, comparative sequence analysis, and molecular modeling.

artículo científico publicado en 2007

Molecular characterization and phylogenetic analysis of BjussuMP-I: a RGD-P-III class hemorrhagic metalloprotease from Bothrops jararacussu snake venom

artículo científico publicado en 2006

Molecular characterization of BjussuSP-I, a new thrombin-like enzyme with procoagulant and kallikrein-like activity isolated from Bothrops jararacussu snake venom

artículo científico publicado en 2007

Molecular cloning and biochemical characterization of a myotoxin inhibitor from Bothrops alternatus snake plasma.

artículo científico publicado en 2010

Molecular cloning and structural modelling of gamma-phospholipase A2 inhibitors from Bothrops atrox and Micrurus lemniscatus snakes.

artículo científico publicado en 2017

Neuromuscular paralysis by the basic phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage.

artículo científico publicado en 2017

Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by importin-α.

artículo científico publicado en 2017

PLA2-like proteins myotoxic mechanism: a dynamic model description

artículo científico publicado en 2017

Phylogenetic and structural studies of a novel equine papillomavirus identified from aural plaques.

artículo científico publicado en 2012

Preliminary X-ray crystallographic studies of BthTX-II, a myotoxic Asp49-phospholipase A2 with low catalytic activity from Bothrops jararacussu venom.

artículo científico publicado en 2006

Preliminary X-ray crystallographic studies of a Lys49-phospholipase A2 homologue from Bothrops pirajai venom complexed with p-bromo-phenacyl bromide and alpha-tocopherol inhibitors.

artículo científico publicado en 2007

Preliminary X-ray crystallographic studies of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom.

artículo científico publicado en 2007

Probing the Specificity of Binding to the Major Nuclear Localization Sequence-binding Site of Importin- Using Oriented Peptide Library Screening

artículo científico publicado en 2010

RPA-1 from Leishmania amazonensis (LaRPA-1) structurally differs from other eukaryote RPA-1 and interacts with telomeric DNA via its N-terminal OB-fold domain.

artículo científico publicado en 2014

Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi

artículo científico publicado en 2016

Replication Protein A-1 Has a Preference for the Telomeric G-rich Sequence in Trypanosoma cruzi.

artículo científico publicado en 2017

Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-α

artículo científico publicado en 2003

Rosmarinic acid, a new snake venom phospholipase A2 inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interaction

artículo científico publicado en 2005

SEQUENCE SLIDER: integration of structural and genetic data to characterize isoforms from natural sources

artículo científico publicado en 2022

Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A-like proteins using functional, structural and bioinformatics approaches

artículo científico publicado en 2019

Secreted Phospholipases A2 from Animal Venoms in Pain and Analgesia

artículo científico publicado en 2017

Snake venom phospholipase A2 inhibitors: medicinal chemistry and therapeutic potential

artículo científico publicado en 2007

Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids

artículo científico publicado en 2015

Structural Biology and Regulation of Protein Import into the Nucleus

artículo científico publicado en 2015

Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence

artículo científico publicado en 2016

Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA2 Inhibition

artículo científico publicado en 2011

Structural and evolutionary insights into endogenous alpha-phospholipase A2 inhibitors of Latin American pit vipers

artículo científico publicado en 2016

Structural and functional characterization of an acidic platelet aggregation inhibitor and hypotensive phospholipase A(2) from Bothrops jararacussu snake venom.

artículo científico publicado en 2002

Structural and functional characterization of neuwiedase, a nonhemorrhagic fibrin(ogen)olytic metalloprotease from Bothrops neuwiedi snake venom.

artículo científico

Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism.

artículo científico publicado en 2018

Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin.

artículo científico publicado en 2015

Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases A₂-like

artículo científico publicado en 2013

Structural and phylogenetic studies with MjTX-I reveal a multi-oligomeric toxin--a novel feature in Lys49-PLA2s protein class

artículo científico publicado en 2013

Structural and thermodynamic studies of the tobacco calmodulin-like rgs-CaM protein

artículo científico publicado en 2016

Structural bases for a complete myotoxic mechanism: crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom

artículo científico publicado en 2013

Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920)

scientific article published on 20 November 2019

Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha

artículo científico publicado en 2003

Structural basis of importin-α-mediated nuclear transport for Ku70 and Ku80

artículo científico publicado en 2011

Structural basis of nuclear import of flap endonuclease 1 (FEN1)

artículo científico publicado en 2012

Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins

scientific article published on 04 August 2018

Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin

artículo científico publicado en 2017

Structural insights for fatty acid binding in a Lys49-phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid

scientific article published on 01 February 2005

Structural studies with BnSP-7 reveal an atypical oligomeric conformation compared to phospholipases A2-like toxins

artículo científico publicado en 2017

Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A₂ class

artículo científico publicado en 2011

Structural-functional studies of animal toxins

artículo científico publicado en 2009

Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 A resolution

artículo científico publicado en 1995

Structure of BthA-I complexed with p-bromophenacyl bromide: possible correlations with lack of pharmacological activity.

artículo científico publicado en 2005

Structure of Importin-α from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal

artículo científico publicado en 2015

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization

artículo científico publicado en 2002

Transcriptionally active LTR retrotransposons in Eucalyptus genus are differentially expressed and insertionally polymorphic

artículo científico publicado en 2015

Triacontyl p-coumarate: an inhibitor of snake venom metalloproteinases

artículo científico publicado en 2012

cDNA sequence and molecular modeling of a nerve growth factor from Bothrops jararacussu venomous gland

artículo científico publicado en 2002

Lista de obras de Marcos R M Fontes

A calmodulin-like protein (LCALA) is a new Leishmania amazonensis candidate for telomere end-binding protein.

A novel synthetic quinolinone inhibitor presents proteolytic and hemorrhagic inhibitory activities against snake venom metalloproteases.

A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms

Alkylation of histidine residues of Bothrops jararacussu venom proteins and isolated phospholipases A2: a biotechnological tool to improve the production of antibodies

An evaluation of 3-rhamnosylquercetin, a glycosylated form of quercetin, against the myotoxic and edematogenic effects of sPLA 2 from Crotalus durissus terrificus

Analysis of Bothrops jararacussu venomous gland transcriptome focusing on structural and functional aspects: I--gene expression profile of highly expressed phospholipases A2.

Anti-Metalloprotease P-I Single-Domain Antibodies: Tools for Next-Generation Snakebite Antivenoms

Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

Biochemical, functional, structural and phylogenetic studies on Intercro, a new isoform phospholipase A2 from Crotalus durissus terrificus snake venom.

Biochemical, pharmacological and structural characterization of BmooMP-I, a new P-I metalloproteinase from Bothrops moojeni venom

Biophysical characterization of interactions involving importin-alpha during nuclear import

Biophysical studies suggest a new structural arrangement of crotoxin and provide insights into its toxic mechanism.

BmajPLA2-II, a basic Lys49-phospholipase A2 homologue from Bothrops marajoensis snake venom with parasiticidal potential.

Bothrops moojeni myotoxin-II, a Lys49-phospholipase A2 homologue: an example of function versatility of snake venom proteins

Cloning and identification of a complete cDNA coding for a bactericidal and antitumoral acidic phospholipase A2 from Bothrops jararacussu venom

Comparative structural studies on Lys49-phospholipases A(2) from Bothrops genus reveal their myotoxic site

Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s

Crotoxin: novel activities for a classic beta-neurotoxin.

Crystal structure of a myotoxic Asp49-phospholipase A2 with low catalytic activity: Insights into Ca2+-independent catalytic mechanism

Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative "myotoxic cluster".

Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A2: quaternary structure and inhibition mechanism insights ⬇️

Crystallization and preliminary X-ray crystallographic analysis of importin-α from Neurospora crassa.

Crystallization and preliminary X-ray diffraction analysis of a Lys49-phospholipase A2complexed with caffeic acid, a molecule with inhibitory properties against snake venoms ⬇️

Crystallization and preliminary X-ray diffraction analysis of a myotoxic Lys49-PLA2 from Bothrops jararacussu venom complexed with p-bromophenacyl bromide.

Crystallization and preliminary X-ray diffraction analysis of a myotoxic phospholipase A(2) homologue from Bothrops neuwiedi pauloensis venom

Crystallization and preliminary X-ray diffraction analysis of an acidic phospholipase A(2) complexed with p-bromophenacyl bromide and alpha-tocopherol inhibitors at 1.9- and 1.45-A resolution

Crystallization and preliminary X-ray diffraction analysis of crotoxin B from Crotalus durissus collilineatus venom

Crystallization and preliminary X-ray diffraction analysis of importin-alpha complexed with NLS peptidomimetics

Crystallization and preliminary X-ray diffraction analysis of three myotoxic phospholipases A2 from Bothrops brazili venom.

Crystallization and preliminary X-ray diffraction studies of BmooPLA2-I, a platelet-aggregation inhibitor and hypotensive phospholipase A2 from Bothrops moojeni venom.

DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway

Functional and structural studies of a Phospholipase A2-like protein complexed to zinc ions: Insights on its myotoxicity and inhibition mechanism.

Geographic variations in the composition of myotoxins from Bothrops neuwiedi snake venoms: biochemical characterization and biological activity

Identification of continuous interaction sites in PLA(2)-based protein complexes by peptide arrays

In Vivo genotoxicity of a commercial C.I. Disperse Red 1 dye

In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum-infected red blood cells

Influence of quaternary conformation on the biological activities of the Asp49-phospholipases A2s from snake venoms

Initiating Structural Studies Of Lys49-Pla2 Homologues Complexed With An Anionic Detergent, A Fatty Acid And A Natural Lipid ⬇️

Insights on the structure of native CNF, an endogenous phospholipase A2 inhibitor from Crotalus durissus terrificus, the South American rattlesnake

Isolation and biochemical characterization of a γ-type phospholipase A2 inhibitor from Crotalus durissus collilineatus snake serum.

Molecular Components of the Neurospora crassa pH Signaling Pathway and Their Regulation by pH and the PAC-3 Transcription Factor

Molecular and functional characterization of a new non-hemorrhagic metalloprotease from Bothrops jararacussu snake venom with antiplatelet activity

Molecular approaches for structural characterization of Bothrops L-amino acid oxidases with antiprotozoal activity: cDNA cloning, comparative sequence analysis, and molecular modeling.

Molecular characterization and phylogenetic analysis of BjussuMP-I: a RGD-P-III class hemorrhagic metalloprotease from Bothrops jararacussu snake venom

Molecular characterization of BjussuSP-I, a new thrombin-like enzyme with procoagulant and kallikrein-like activity isolated from Bothrops jararacussu snake venom

Molecular cloning and biochemical characterization of a myotoxin inhibitor from Bothrops alternatus snake plasma.

Molecular cloning and structural modelling of gamma-phospholipase A2 inhibitors from Bothrops atrox and Micrurus lemniscatus snakes.

Neuromuscular paralysis by the basic phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage.

Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by importin-α.

PLA2-like proteins myotoxic mechanism: a dynamic model description

Phylogenetic and structural studies of a novel equine papillomavirus identified from aural plaques.

Preliminary X-ray crystallographic studies of BthTX-II, a myotoxic Asp49-phospholipase A2 with low catalytic activity from Bothrops jararacussu venom.

Preliminary X-ray crystallographic studies of a Lys49-phospholipase A2 homologue from Bothrops pirajai venom complexed with p-bromo-phenacyl bromide and alpha-tocopherol inhibitors.

Preliminary X-ray crystallographic studies of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom.

Probing the Specificity of Binding to the Major Nuclear Localization Sequence-binding Site of Importin- Using Oriented Peptide Library Screening

RPA-1 from Leishmania amazonensis (LaRPA-1) structurally differs from other eukaryote RPA-1 and interacts with telomeric DNA via its N-terminal OB-fold domain.

Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi

Replication Protein A-1 Has a Preference for the Telomeric G-rich Sequence in Trypanosoma cruzi.

Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-α

Rosmarinic acid, a new snake venom phospholipase A2 inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interaction

SEQUENCE SLIDER: integration of structural and genetic data to characterize isoforms from natural sources

Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A-like proteins using functional, structural and bioinformatics approaches

Secreted Phospholipases A2 from Animal Venoms in Pain and Analgesia

Snake venom phospholipase A2 inhibitors: medicinal chemistry and therapeutic potential

Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids

Structural Biology and Regulation of Protein Import into the Nucleus

Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence

Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA2 Inhibition

Structural and evolutionary insights into endogenous alpha-phospholipase A2 inhibitors of Latin American pit vipers

Structural and functional characterization of an acidic platelet aggregation inhibitor and hypotensive phospholipase A(2) from Bothrops jararacussu snake venom.

Structural and functional characterization of neuwiedase, a nonhemorrhagic fibrin(ogen)olytic metalloprotease from Bothrops neuwiedi snake venom.

Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism.

Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin.

Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases A₂-like

Structural and phylogenetic studies with MjTX-I reveal a multi-oligomeric toxin--a novel feature in Lys49-PLA2s protein class

Structural and thermodynamic studies of the tobacco calmodulin-like rgs-CaM protein

Structural bases for a complete myotoxic mechanism: crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom

Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920)

Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha