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Lista de obras de Daniel J Sargent

A 2-Stage Phase II Design with Direct Assignment Option in Stage II for Initial Marker Validation ⬇️

artículo científico publicado el 14 de junio de 2012

A Bayesian dose-finding design incorporating toxicity data from multiple treatment cycles

artículo científico publicado en 2016

A comparison of laparoscopically assisted and open colectomy for colon cancer

scientific article published on 01 May 2004

A false-discovery-rate-based loss framework for selection of interactions

artículo científico publicado en 2008

A general framework for random effects survival analysis in the Cox proportional hazards setting

artículo científico publicado en 1998

A new graphic for quality adjusted life years (Q-TWiST) survival analysis: the Q-TWiST plot

artículo científico publicado en 2002

A phase I study of radiation therapy and twice-weekly gemcitabine and cisplatin in patients with locally advanced pancreatic cancer

artículo científico publicado en 2003

A phase II flexible screening design allowing for interim analysis and comparison with historical control

artículo científico publicado en 2013

A pilot study of high-dose intraarterial cisplatin chemotherapy with concomitant accelerated radiotherapy for patients with previously untreated T4 and selected patients with T3N0-N3M0 squamous cell carcinoma of the upper aerodigestive tract

artículo científico publicado en 2005

A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients

artículo científico publicado en 2001

A prospective randomized trial comparing standard pancreatoduodenectomy with pancreatoduodenectomy with extended lymphadenectomy in resectable pancreatic head adenocarcinoma

scientific article published on 01 October 2005

A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer.

artículo científico publicado en 2003

A review of phase II trial designs for initial marker validation.

artículo científico publicado en 2013

A three-outcome design for phase II clinical trials.

artículo científico publicado en 2001

Achieving sufficient accrual to address the primary endpoint in phase III clinical trials from U.S. Cooperative Oncology Groups

artículo científico publicado en 2011

Acute diarrhea during adjuvant therapy for rectal cancer: a detailed analysis from a randomized intergroup trial

artículo científico publicado en 2002

Acute treatment-related diarrhea during postoperative adjuvant therapy for high-risk rectal carcinoma.

artículo científico publicado en 1998

Adaptive adjustment of the randomization ratio using historical control data

artículo científico publicado en 2013

Adjuvant therapy for colon cancer--the pace quickens

artículo científico publicado en 2005

Adverse-event rates: journals versus databases

artículo científico publicado en 2007

All-Comers versus Enrichment Design Strategy in Phase II Trials ⬇️

artículo científico publicado el 1 de abril de 2011

Alterations in cell proliferation and apoptosis in colon cancers with microsatellite instability.

artículo científico publicado en 2007

Alternate endpoints for screening phase II studies.

artículo científico publicado en 2009

Alternative end points to evaluate a therapeutic strategy in advanced colorectal cancer: evaluation of progression-free survival, duration of disease control, and time to failure of strategy--an Aide et Recherche en Cancerologie Digestive Group Stud

artículo científico publicado en 2011

An adaptive dose-finding design incorporating both toxicity and efficacy

artículo científico publicado en 2006

An adaptive phase I design for identifying a biologically optimal dose for dual agent drug combinations

artículo científico publicado en 2007

Application of tumor measurement-based metrics in the real world

artículo científico publicado en 2013

Assessing the measure of a new drug: is survival the only thing that matters?

artículo científico publicado en 2008

Association between disease-free survival and overall survival when survival is prolonged after recurrence in patients receiving cytotoxic adjuvant therapy for colon cancer: simulations based on the 20,800 patient ACCENT data set

artículo científico publicado en 2009

Association of age with survival in patients with metastatic colorectal cancer: analysis from the ARCAD Clinical Trials Program

artículo científico publicado en 2014

Association of obesity with DNA mismatch repair status and clinical outcome in patients with stage II or III colon carcinoma participating in NCCTG and NSABP adjuvant chemotherapy trials

artículo científico publicado en 2011

Association study of the let-7 miRNA-complementary site variant in the 3' untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 Clinical Trial).

artículo científico publicado en 2014

Associations between cigarette smoking status and colon cancer prognosis among participants in North Central Cancer Treatment Group Phase III Trial N0147

artículo científico publicado en 2013

Associations between plasma insulin-like growth factor proteins and C-peptide and quality of life in patients with metastatic colorectal cancer

artículo científico publicado en 2005

Bayesian Adaptive Trial Design for a Newly Validated Surrogate Endpoint ⬇️

artículo científico publicado el 12 de agosto de 2011

Bayesian adjusted R2 for the meta-analytic evaluation of surrogate time-to-event endpoints in clinical trials

artículo científico publicado en 2011

Bayesian variable selection with joint modeling of categorical and survival outcomes: an application to individualizing chemotherapy treatment in advanced colorectal cancer

artículo científico publicado en 2009

Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis

artículo científico publicado en 2010

Benefits and adverse events in younger versus older patients receiving adjuvant chemotherapy for colon cancer: findings from the Adjuvant Colon Cancer Endpoints data set

artículo científico publicado en 2012

Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE)

scientific article published on 14 October 2008

Body mass index at diagnosis and survival among colon cancer patients enrolled in clinical trials of adjuvant chemotherapy

artículo científico publicado en 2013

CAUSAL EFFECTS OF TREATMENTS FOR INFORMATIVE MISSING DATA DUE TO PROGRESSION/DEATH ⬇️

artículo científico publicado el 1 de septiembre de 2010

Calibration of quality-adjusted life years for oncology clinical trials.

artículo científico publicado en 2013

Causal assessment of surrogacy in a meta-analysis of colorectal cancer trials

artículo científico publicado en 2011

Center-Within-Trial Versus Trial-Level Evaluation of Surrogate Endpoints

artículo científico publicado en 2014

Challenges to accrual predictions to phase III cancer clinical trials: a survey of study chairs and lead statisticians of 248 NCI-sponsored trials

artículo científico publicado en 2011

Characterization of antigen processing machinery and Survivin expression in tonsillar squamous cell carcinoma

scientific article published on 01 May 2003

Clinical implications of microsatellite instability in sporadic colon cancers

scientific article published on July 2009

Clinical predictors of severe cetuximab-induced rash: observations from 933 patients enrolled in north central cancer treatment group study N0147.

artículo científico publicado en 2009

Clinical trial designs for predictive biomarker validation: one size does not fit all.

artículo científico publicado en 2009

Clinical trial designs for predictive biomarker validation: theoretical considerations and practical challenges.

artículo científico publicado en 2009

Clinical trial designs for predictive marker validation in cancer treatment trials

artículo científico publicado en 2005

Clinical trial designs for prospective validation of biomarkers

artículo científico publicado en 2005

Clinical trials data collection: when less is more

artículo científico publicado en 2010

Commensurate Priors for Incorporating Historical Information in Clinical Trials Using General and Generalized Linear Models

artículo científico publicado en 2012

Comparative effectiveness of oxaliplatin vs non-oxaliplatin-containing adjuvant chemotherapy for stage III colon cancer

artículo científico publicado en 2012

Comparison of FOLFIRI with or without cetuximab in patients with resected stage III colon cancer; NCCTG (Alliance) intergroup trial N0147.

artículo científico publicado en 2013

Comparison of continuous versus categorical tumor measurement-based metrics to predict overall survival in cancer treatment trials

artículo científico publicado en 2011

Comparison of error rates in single-arm versus randomized phase II cancer clinical trials

artículo científico publicado en 2010

Comparison of histopathology and RT-qPCR amplification of guanylyl cyclase C for detection of colon cancer metastases in lymph nodes

artículo científico publicado en 2010

Cost implications of new treatments for advanced colorectal cancer.

artículo científico publicado en 2009

Cost-effectiveness projections of oxaliplatin and infusional fluorouracil versus irinotecan and bolus fluorouracil in first-line therapy for metastatic colorectal carcinoma

artículo científico publicado en 2005

Curative potential of multimodality therapy for locally recurrent rectal cancer.

artículo científico publicado en 2003

Current Use and Surgical Efficacy of Laparoscopic Colectomy in Colon Cancer ⬇️

artículo científico publicado el 24 de abril de 2013

Current issues in oncology drug development, with a focus on Phase II trials

artículo científico publicado en 2009

DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy.

artículo científico publicado en 2011

Dealing with a deluge of data: an assessment of adverse event data on North Central Cancer Treatment Group trials

artículo científico publicado en 2005

Decrease in cranial nerve complications after radiosurgery for acoustic neuromas: a prospective study of dose and volume

article

Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer

artículo científico publicado en 2010

Definition of disease-free survival: this is my truth–show me yours

artículo científico publicado en 2005

Designing a randomized clinical trial to evaluate personalized medicine: a new approach based on risk prediction ⬇️

artículo científico publicado el 1 de diciembre de 2010

Development and Independent Validation of a Prognostic Assay for Stage II Colon Cancer Using Formalin-Fixed Paraffin-Embedded Tissue

artículo científico publicado en 2011

Disease-free survival as a surrogate for overall survival in adjuvant trials of gastric cancer: a meta-analysis

artículo científico publicado en 2013

Disease-free survival in colon cancer: still relevant after all these years!

artículo científico publicado en 2013

Disease-free survival versus overall survival as a primary end point for adjuvant colon cancer studies: individual patient data from 20,898 patients on 18 randomized trials

artículo científico publicado en 2005

Drug rechallenge and treatment beyond progression--implications for drug resistance.

artículo científico publicado en 2013

Duffy-Santner confidence intervals for the two-stage three-outcome design

artículo científico publicado en 2006

Early detection of toxicity and adjustment of ongoing clinical trials: the history and performance of the North Central Cancer Treatment Group's real-time toxicity monitoring program

artículo científico publicado en 2002

Early stopping for benefit in National Cancer Institute-sponsored randomized Phase III trials: the system is working

artículo científico publicado en 2009

Effect of Oxaliplatin, Fluorouracil, and Leucovorin With or Without Cetuximab on Survival Among Patients With Resected Stage III Colon Cancer ⬇️

artículo científico publicado el 4 de abril de 2012

Efficacy and quality-of-life data are related in a phase II trial of oral chemotherapy in previously untreated patients with metastatic colorectal carcinoma

artículo científico publicado en 2002

End points for adjuvant therapy trials: has the time come to accept disease-free survival as a surrogate end point for overall survival?

artículo científico publicado en 2006

End points for colon cancer adjuvant trials: observations and recommendations based on individual patient data from 20,898 patients enrolled onto 18 randomized trials from the ACCENT Group

artículo científico publicado en 2007

Enhanced therapeutic potential of adoptive immunotherapy by in vitro CD28/4-1BB costimulation of tumor-reactive T cells against a poorly immunogenic, major histocompatibility complex class I-negative A9P melanoma

artículo científico publicado en 2000

Evaluation of alternate categorical tumor metrics and cut points for response categorization using the RECIST 1.1 data warehouse

artículo científico publicado en 2014

Evaluation of guanylyl cyclase C lymph node status for colon cancer staging and prognosis.

artículo científico publicado en 2011

Evaluation of the optimal number of lesions needed for tumor evaluation using the response evaluation criteria in solid tumors: a north central cancer treatment group investigation.

artículo científico publicado en 2009

Evaluation of the value of attribution in the interpretation of adverse event data: a North Central Cancer Treatment Group and American College of Surgeons Oncology Group investigation

artículo científico publicado en 2010

Evidence for cure by adjuvant therapy in colon cancer: observations based on individual patient data from 20,898 patients on 18 randomized trials

artículo científico publicado en 2009

Exploring and validating surrogate endpoints in colorectal cancer

scientific article published on 20 January 2008

Exploring racial differences in outcome and treatment for metastatic colorectal cancer: results from a large prospective observational cohort study (BRiTE).

artículo científico publicado en 2011

Exploring the statistical and clinical impact of two interim analyses on the Phase II design with option for direct assignment

artículo científico publicado en 2014

FDG-PET lymphoma demonstration project invitational workshop

scientific article published on 01 March 2007

FOLFOX for stage II colon cancer? A commentary on the recent FDA approval of oxaliplatin for adjuvant therapy of stage III colon cancer

artículo científico publicado en 2005

Failure of bevacizumab in early-stage colon cancer ⬇️

artículo científico publicado el 30 de noviembre de 2010

Family history of colorectal cancer and its impact on survival in patients with resected stage III colon cancer: results from NCCTG Trial N0147 (Alliance).

artículo científico publicado en 2017

Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741

artículo científico publicado en 2008

From isolated hypotheses to connected practical studies: statisticians' role in a seamless targeted therapy development

artículo científico publicado en 2012

Functional and clinical significance of variants localized to 8q24 in colon cancer

artículo científico publicado en 2009

Gemcitabine and oxaliplatin for metastatic pancreatic adenocarcinoma: a North Central Cancer Treatment Group phase II study.

artículo científico publicado en 2003

Gemcitabine and oxaliplatin for patients with advanced or metastatic pancreatic cancer: a North Central Cancer Treatment Group (NCCTG) phase I study

artículo científico publicado en 2002

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis

artículo científico publicado en 2014

Germline variation in colorectal risk Loci does not influence treatment effect or survival in metastatic colorectal cancer.

artículo científico publicado en 2014

Hierarchical commensurate and power prior models for adaptive incorporation of historical information in clinical trials.

artículo científico publicado en 2011

Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors

artículo científico publicado en 2002

Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis.

artículo científico publicado en 2004

Impact of T and N substage on survival and disease relapse in adjuvant rectal cancer: a pooled analysis.

artículo científico publicado en 2002

Impact of complete response to chemotherapy on overall survival in advanced colorectal cancer: results from Intergroup N9741.

artículo científico publicado en 2007

Impact of young age on treatment efficacy and safety in advanced colorectal cancer: a pooled analysis of patients from nine first-line phase III chemotherapy trials

artículo científico publicado en 2011

Incorporation of Biomarker Assessment in Novel Clinical Trial Designs: Personalizing Brain Tumor Treatments ⬇️

artículo científico publicado el 1 de febrero de 2011

Individual patient data analysis to assess modifications to the RECIST criteria.

artículo científico publicado en 2008

Innovative estimation of survival using log-normal survival modelling on ACCENT database.

artículo científico publicado en 2013

Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma

artículo científico publicado en 2009

Intraoperative radiotherapy for head and neck and skull base cancer

scientific article published on 01 March 2003

Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer

artículo científico publicado en 2002

Isolated loss of PMS2 expression in colorectal cancers: frequency, patient age, and familial aggregation

artículo científico publicado en 2005

Issues in clinical trial design for tumor marker studies

artículo científico publicado en 2002

KRAS codon 12 and 13 mutations in relation to disease-free survival in BRAF-wild-type stage III colon cancers from an adjuvant chemotherapy trial (N0147 alliance).

artículo científico publicado en 2014

Laparoscopic colectomy for cancer is not inferior to open surgery based on 5-year data from the COST Study Group trial

artículo científico publicado en 2007

Laparoscopically assisted vs open colectomy for colon cancer: a meta-analysis

artículo científico publicado en 2007

Long-term follow-up and individual item analysis of quality of life assessments related to laparoscopic-assisted colectomy in the COST trial 93-46-53 (INT 0146)

scientific article published on 31 March 2011

Long-term survivors of metastatic colorectal cancer treated with systemic chemotherapy alone: a North Central Cancer Treatment Group review of 3811 patients, N0144.

artículo científico publicado en 2009

Meta-analysis for surrogacy: accelerated failure time models and semicompeting risks modeling

artículo científico publicado en 2011

Meta-analysis for the evaluation of surrogate endpoints in cancer clinical trials.

artículo científico publicado en 2009

Microsatellite instability accounts for tumor site-related differences in clinicopathologic variables and prognosis in human colon cancers

artículo científico publicado en 2006

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.

artículo científico publicado en 2017

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.

artículo científico publicado en 2017

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology.

artículo científico publicado en 2017

Molecular diagnostics: assays, tissues, progress, and pitfalls

artículo científico publicado en 2003

Molecular pathways: microsatellite instability in colorectal cancer: prognostic, predictive, and therapeutic implications

artículo científico publicado en 2012

Mortality associated with daily bolus 5-fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin: results from Intergroup Trial N9741.

artículo científico publicado en 2004

Multi-state models for colon cancer recurrence and death with a cured fraction

artículo científico publicado en 2013

NCCTG Study N9741: leveraging learning from an NCI Cooperative Group phase III trial.

artículo científico publicado en 2009

New insights into the evaluation of randomized controlled trials for rare diseases over a long-term research horizon: a simulation study

artículo científico publicado en 2016

New lessons from "old" chemotherapy in colorectal cancer

artículo científico publicado en 2008

New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

artículo científico publicado en 2009

New treatment options for colorectal cancer

artículo científico publicado en 2004

Obesity is an independent prognostic variable in colon cancer survivors

artículo científico publicado en 2010

On Bayesian methods of exploring qualitative interactions for targeted treatment.

artículo científico publicado en 2012

Optimising the design of phase II oncology trials: the importance of randomisation

artículo científico publicado en 2008

Outcomes among black patients with stage II and III colon cancer receiving chemotherapy: an analysis of ACCENT adjuvant trials

artículo científico publicado en 2011

Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line

artículo científico publicado en 2005

Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase II study

artículo científico publicado en 2005

Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: results from North American Gastrointestinal Intergroup Trial N9741.

artículo científico publicado en 2010

Phase III noninferiority trial comparing irinotecan with oxaliplatin, fluorouracil, and leucovorin in patients with advanced colorectal carcinoma previously treated with fluorouracil: N9841.

artículo científico publicado en 2009

Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: results of intergroup protocol 0130.

artículo científico publicado en 2004

Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741.

artículo científico publicado en 2008

Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: who benefits and by how much?

artículo científico publicado en 2004

Pooled analysis of safety and efficacy of oxaliplatin plus fluorouracil/leucovorin administered bimonthly in elderly patients with colorectal cancer

artículo científico publicado en 2006

Pooled safety and efficacy analysis examining the effect of performance status on outcomes in nine first-line treatment trials using individual data from patients with metastatic colorectal cancer

artículo científico publicado en 2009

Postoperative surveillance recommendations for early stage colon cancer based on results from the clinical outcomes of surgical therapy trial.

artículo científico publicado en 2009

Predicting treatment effect from surrogate endpoints and historical trials: an extrapolation involving probabilities of a binary outcome or survival to a specific time

artículo científico publicado en 2011

Prediction of radial distance of extraprostatic extension from pretherapy factors

artículo científico publicado en 2007

Predictive biomarker validation in practice: lessons from real trials

artículo científico publicado en 2010

Predictive biomarkers in colorectal cancer: usage, validation, and design in clinical trials.

artículo científico

Preliminary evaluation of factors associated with premature trial closure and feasibility of accrual benchmarks in phase III oncology trials

artículo científico publicado en 2010

Priorities in colorectal cancer research: recommendations from the Gastrointestinal Scientific Leadership Council of the Coalition of Cancer Cooperative Groups.

artículo científico publicado en 2007

Proapoptotic Bad and Bid protein expression predict survival in stages II and III colon cancers

artículo científico publicado en 2008

Prognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR status

artículo científico publicado en 2009

Prognostic impact of FoxP3+ regulatory T cells in relation to CD8+ T lymphocyte density in human colon carcinomas

artículo científico publicado en 2012

Prognostic impact of bim, puma, and noxa expression in human colon carcinomas.

artículo científico publicado en 2008

Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients

artículo científico publicado en 2006

Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer.

artículo científico publicado en 2008

Prognostic value of proliferation, apoptosis, defective DNA mismatch repair, and p53 overexpression in patients with resected Dukes' B2 or C colon cancer: a North Central Cancer Treatment Group Study

artículo científico publicado en 2004

Progression-free survival as a surrogate for overall survival in advanced/recurrent gastric cancer trials: a meta-analysis

scientific article published on 09 October 2013

Progression-free survival is a surrogate for survival in advanced colorectal cancer

artículo científico publicado en 2007

Racial differences in advanced colorectal cancer outcomes and pharmacogenetics: a subgroup analysis of a large randomized clinical trial.

artículo científico publicado en 2009

Random effects survival models gave a better understanding of heterogeneity in individual patient data meta-analyses.

artículo científico publicado en 2005

Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: a North American Intergroup Tri

artículo científico publicado en 2006

Randomized phase II clinical trials

artículo científico publicado en 2014

Randomized phase II designs.

artículo científico publicado en 2009

Randomized phase II trials: inevitable or inadvisable?

artículo científico publicado en 2010

Randomized phase II trials: time for a new era in clinical trial design

artículo científico publicado en 2010

Recommendation for caution with irinotecan, fluorouracil, and leucovorin for colorectal cancer

artículo científico publicado en 2001

Refining multimodal therapy for rectal cancer

artículo científico publicado en 2001

Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial

artículo científico publicado en 2013

Rejoinder for “Meta‐analysis for Surrogacy: Accelerated Failure Time Models and Semicompeting Risks Modeling” ⬇️

artículo científico publicado el 13 de junio de 2011

Research outcomes and recommendations for the assessment of progression in cancer clinical trials from a PhRMA working group.

artículo científico publicado en 2011

Response-independent survival benefit in metastatic colorectal cancer: a comparative analysis of N9741 and AVF2107.

artículo científico publicado en 2008

Revised TN categorization for colon cancer based on national survival outcomes data

artículo científico publicado en 2009

Revised tumor and node categorization for rectal cancer based on surveillance, epidemiology, and end results and rectal pooled analysis outcomes

artículo científico publicado en 2009

Robust Bayesian approaches for clinical trial monitoring

artículo científico publicado en 1996

Role of chemotherapy for advanced/recurrent gastric cancer: An individual-patient-data meta-analysis ⬇️

artículo científico publicado el 24 de enero de 2013

Role of sensitivity analyses in assessing progression-free survival in late-stage oncology trials

artículo científico publicado en 2009

Sample size and design considerations for phase II clinical trials with correlated observations

artículo científico publicado en 1999

Single agent fluorouracil for first-line treatment of advanced colorectal cancer as standard?

scientific article published on 01 July 2007

Sound footing or slippery slope? The value of secondary analyses of randomized trials

scientific article published on 01 August 2007

Statistical Considerations for the Next Generation of Clinical Trials ⬇️

artículo científico publicado el 1 de agosto de 2011

Statistical issues in the validation of prognostic, predictive, and surrogate biomarkers

artículo científico publicado en 2013

Substitution of oral fluoropyrimidines for infusional fluorouracil with radiotherapy: how much data do we need?

artículo científico publicado en 2004

Surgical quality surrogates do not predict colon cancer survival in the setting of technical credentialing: a report from the prospective COST trial

artículo científico publicado en 2013

Surrogate endpoint validation: statistical elegance versus clinical relevance.

artículo científico publicado en 2008

Survival following recurrence in stage II and III colon cancer: findings from the ACCENT data set.

artículo científico publicado en 2008

Survival is not a good outcome for randomized trials with effective subsequent therapies.

artículo científico publicado en 2011

Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment

artículo científico publicado en 2004

Swallow function in patients before and after intra-arterial chemoradiation

scientific article published on 01 March 2003

Systematic review of statistical methods used in molecular marker studies in cancer

artículo científico publicado en 2008

Systemic therapy for elderly patients with gastrointestinal cancer.

artículo científico publicado en 2011

Taking the long view: how to design a series of Phase III trials to maximize cumulative therapeutic benefit ⬇️

artículo científico publicado el 8 de mayo de 2012

Testing of evaluation bias for progression free survival endpoint in oncology clinical trials

artículo científico publicado en 2016

The ARCAD Clinical Trials Program: An Update and Invitation ⬇️

artículo científico publicado el 2 de febrero de 2012

The ARCAD advanced colorectal cancer database--open for business

scientific article published on 21 November 2011

The IDEA (International Duration Evaluation of Adjuvant Chemotherapy) Collaboration: Prospective Combined Analysis of Phase III Trials Investigating Duration of Adjuvant Therapy with the FOLFOX (FOLFOX4 or Modified FOLFOX6) or XELOX (3 versus 6 [...]

artículo científico publicado en 2013

The IDEA Collaboration: Prospective Combined Analysis of Phase III Trials Investigating Duration of Adjuvant Therapy with the FOLFOX Regimen for Patients with Stage III Colon Cancer: Current Status

artículo científico publicado en 2014

The components of progression as explanatory variables for overall survival in the Response Evaluation Criteria in Solid Tumours 1.1 database.

artículo científico publicado en 2014

The design of phase II clinical trials testing cancer therapeutics: consensus recommendations from the clinical trial design task force of the national cancer institute investigational drug steering committee

artículo científico publicado en 2010

The predictive and prognostic value of sex in early-stage colon cancer: a pooled analysis of 33,345 patients from the ACCENT database

artículo científico publicado en 2013

The radial distance of extraprostatic extension of prostate carcinoma: implications for prostate brachytherapy

artículo científico publicado en 1999

The role of response evaluation criteria in solid tumour in anticancer treatment evaluation: results of a survey in the oncology community.

artículo científico publicado en 2013

Thymidylate synthase expression in colon carcinomas with microsatellite instability

artículo científico publicado en 2006

Time to initiation of adjuvant chemotherapy and survival in colorectal cancer

Toward Efficient Trials in Colorectal Cancer: The ARCAD Clinical Trials Program

artículo científico publicado en 2009

Treatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841.

artículo científico publicado en 2011

Tumor status at 12 weeks predicts survival in advanced colorectal cancer: findings from NCCTG N9741

artículo científico publicado en 2011

Updated efficacy and toxicity analysis of irinotecan and oxaliplatin (IROX) : intergroup trial N9741 in first-line treatment of metastatic colorectal cancer

artículo científico publicado en 2007

Use of intraoperative electron beam radiotherapy in the management of retroperitoneal soft tissue sarcomas

artículo científico publicado en 2002

Using cure models and multiple imputation to utilize recurrence as an auxiliary variable for overall survival.

artículo científico publicado en 2011

Validation of novel imaging methodologies for use as cancer clinical trial end-points

artículo científico publicado en 2008

Vitamin D status in patients with stage IV colorectal cancer: findings from Intergroup trial N9741.

artículo científico publicado en 2011

Women experience greater toxicity with fluorouracil-based chemotherapy for colorectal cancer

artículo científico publicado en 2002

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