Lista de obras - Wanting Jiao - Dominio Público Uruguay

A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase.

artículo científico publicado en 2017

A single amino acid substitution uncouples catalysis and allostery in an essential biosynthetic enzyme in Mycobacterium tuberculosis

artículo científico publicado en 2020

Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2

artículo científico publicado en 2019

An extended β7α7 substrate-binding loop is essential for efficient catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase

artículo científico publicado en 2011

Arg314 is essential for catalysis by N-acetyl neuraminic acid synthase from Neisseria meningitidis

artículo científico publicado en 2013

Change in Heat Capacity for Enzyme Catalysis Determines Temperature Dependence of Enzyme Catalyzed Rates

artículo científico publicado en 2017

Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates

artículo científico publicado en 2013

Conformational interdomain flexibility in a bacterial α-isopropylmalate synthase is necessary for leucine biosynthesis

artículo científico publicado en 2023

Crystal structure of type II NADH:quinone oxidoreductase from Caldalkalibacillus thermarum with an improved resolution of 2.15 Å.

artículo científico publicado en 2017

Diverse allosteric componentry and mechanisms control entry into aromatic metabolite biosynthesis

artículo científico publicado en 2020

Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery

artículo científico publicado en 2012

Hinge Twists and Population Shifts Deliver Regulated Catalysis for ATP-PRT in Histidine Biosynthesis

scientific article published on 09 April 2019

Molecular modeling studies of peptide inhibitors highlight the importance of conformational prearrangement for inhibition of calpain

artículo científico publicado en 2010

New tripeptide-based macrocyclic calpain inhibitors formed by N-alkylation of histidine

artículo científico publicado en 2012

Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based design

artículo científico publicado en 2011

Precise Positioning of Water Is Critical for Hydrolysis Catalyzed by 5′-Methylthioadenosine Nucleosidase

artículo científico publicado en 2022

Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using ᴅ-Amino Acids

artículo científico publicado en 2016

Probing the determinants of phosphorylated sugar-substrate binding for human sialic acid synthase

scientific article published on 19 September 2014

Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis

artículo científico publicado en 2017

Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors

artículo científico publicado en 2018

Structure, mechanism and inhibition of anthranilate phosphoribosyltransferase

artículo científico publicado en 2023

Substrate-mediated control of the conformation of an ancillary domain delivers a competent catalytic site for N-acetylneuraminic acid synthase

Synergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis

artículo científico publicado en 2010

Synthesis and evaluation of dual site inhibitors of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase

artículo científico publicado en 2011

Synthesis of sulfamide analogues of deoxthymidine monophosphate as potential inhibitors of mycobacterial cell wall biosynthesis

artículo científico publicado en 2018

The Use of Molecular Modelling to Study Enzymic Action ⬇️

2011 doctoral thesis by Wanting Jiao at University of Canterbury

Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis

artículo científico publicado en 2013

Using a combination of computational and experimental techniques to understand the molecular basis for protein allostery

artículo científico publicado en 2012

‘Tethering’ fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase

artículo científico publicado en 2018

Lista de obras de Wanting Jiao

A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase.

A single amino acid substitution uncouples catalysis and allostery in an essential biosynthetic enzyme in Mycobacterium tuberculosis

Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2

An extended β7α7 substrate-binding loop is essential for efficient catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase

Arg314 is essential for catalysis by N-acetyl neuraminic acid synthase from Neisseria meningitidis

Change in Heat Capacity for Enzyme Catalysis Determines Temperature Dependence of Enzyme Catalyzed Rates

Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates

Conformational interdomain flexibility in a bacterial α-isopropylmalate synthase is necessary for leucine biosynthesis

Crystal structure of type II NADH:quinone oxidoreductase from Caldalkalibacillus thermarum with an improved resolution of 2.15 Å.

Diverse allosteric componentry and mechanisms control entry into aromatic metabolite biosynthesis

Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery

Hinge Twists and Population Shifts Deliver Regulated Catalysis for ATP-PRT in Histidine Biosynthesis

Molecular modeling studies of peptide inhibitors highlight the importance of conformational prearrangement for inhibition of calpain

New tripeptide-based macrocyclic calpain inhibitors formed by N-alkylation of histidine

Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based design

Precise Positioning of Water Is Critical for Hydrolysis Catalyzed by 5′-Methylthioadenosine Nucleosidase

Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using ᴅ-Amino Acids

Probing the determinants of phosphorylated sugar-substrate binding for human sialic acid synthase

Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis

Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors

Structure, mechanism and inhibition of anthranilate phosphoribosyltransferase

Substrate-mediated control of the conformation of an ancillary domain delivers a competent catalytic site for N-acetylneuraminic acid synthase

Synergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis

Synthesis and evaluation of dual site inhibitors of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase

Synthesis of sulfamide analogues of deoxthymidine monophosphate as potential inhibitors of mycobacterial cell wall biosynthesis

The Use of Molecular Modelling to Study Enzymic Action ⬇️

Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis

Using a combination of computational and experimental techniques to understand the molecular basis for protein allostery

‘Tethering’ fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase