Lista de obras - Angelo Poletti - Dominio Público Uruguay

17-AAG increases autophagic removal of mutant androgen receptor in spinal and bulbar muscular atrophy.

artículo científico publicado en 2010

5 alpha-reductase activity in isolated and cultured neuronal and glial cells of the rat.

artículo científico publicado en 1990

5 alpha-reductase isozymes in the central nervous system

artículo científico publicado en 1998

5alpha-reductase isozymes and aromatase are differentially expressed and active in the androgen-independent human prostate cancer cell lines DU145 and PC3

scientific article published on 01 December 1999

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.

artículo científico publicado en 2016

A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae

artículo científico publicado en 1992

A presynaptically toxic secreted phospholipase A2 is internalized into motoneuron-like cells where it is rapidly translocated into the cytosol.

artículo científico publicado en 2008

A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases

artículo científico publicado en 2010

ALS-related misfolded protein management in motor neurons and muscle cells

artículo científico publicado en 2014

Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy.

artículo científico publicado en 2015

Aggregation and proteasome: the case of elongated polyglutamine aggregation in spinal and bulbar muscular atrophy.

artículo científico publicado en 2006

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins.

artículo científico publicado en 2011

Androgen 5-alpha-reductase type 2 is highly expressed and active in rat spinal cord motor neurones

artículo científico publicado en 2003

Androgen Metabolism in Different Target Tissues ⬇️

artículo científico publicado el 1 de enero de 1990

Androgen receptor activation by polychlorinated biphenyls: epigenetic effects mediated by the histone demethylase Jarid1b.

scientific article published on August 2013

Androgen regulates neuritin mRNA levels in an in vivo model of steroid-enhanced peripheral nerve regeneration

artículo científico publicado en 2008

Androgen regulation of axon growth and neurite extension in motoneurons

artículo científico publicado en 2008

Androgen-induced neurite outgrowth is mediated by neuritin in motor neurones.

artículo científico publicado en 2005

Androgens affect muscle, motor neuron, and survival in a mouse model of SOD1-related amyotrophic lateral sclerosis

article

Autophagic and Proteasomal Mediated Removal of Mutant Androgen Receptor in Muscle Models of Spinal and Bulbar Muscular Atrophy

scientific article published on 20 August 2019

BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch.

artículo científico publicado en 2014

C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation

artículo científico publicado en 2021

CAG repeat length in androgen receptor gene is not associated with amyotrophic lateral sclerosis.

artículo científico publicado en 2012

Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy.

artículo científico publicado en 2013

Combinatorial treatment for spinal muscular atrophy: An Editorial for 'Combined treatment with the histone deacetylase inhibitor LBH589 and a splice-switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atroph

artículo científico publicado en 2020

Concurrent AFG3L2 and SPG7 mutations associated with syndromic parkinsonism and optic atrophy with aberrant OPA1 processing and mitochondrial network fragmentation

artículo científico publicado en 2018

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.

artículo científico publicado en 2014

Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

artículo científico

Differential autophagy power in the spinal cord and muscle of transgenic ALS mice.

artículo científico publicado en 2013

Dihydrotestosterone decreases tumor necrosis factor-alpha and lipopolysaccharide-induced inflammatory response in human endothelial cells.

artículo científico publicado en 2005

Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells

scientific article published on 30 August 2018

Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: implication for protein aggregation and immune response.

artículo científico

Dysregulation of axonal transport and motorneuron diseases.

artículo científico publicado en 2011

Effect of postnatal starvation on the 5 alpha-reductase activity of the brain and of the isolated myelin membranes

artículo científico publicado en 1989

Effect of suramin on the biological activity of the two isoforms of the rat 5 alpha-reductase

artículo científico publicado en 1996

Enhanced Clearance of Neurotoxic Misfolded Proteins by the Natural Compound Berberine and Its Derivatives ⬇️

artículo científico publicado en 2020

Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol.

artículo científico publicado en 2010

Estrogens, Neuroinflammation, and Neurodegeneration.

artículo científico publicado en 2016

Exome sequencing identifies variants in two genes encoding the LIM-proteins NRAP and FHL1 in an Italian patient with BAG3 myofibrillar myopathy.

artículo científico publicado en 2016

FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

scientific article published on 01 April 2019

Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.

artículo científico publicado en 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

HSC70 expression is reduced in lymphomonocytes of sporadic ALS patients and contributes to TDP-43 accumulation

artículo científico publicado en 2019

Human adipose-derived mesenchymal stem cells as a new model of spinal and bulbar muscular atrophy.

artículo científico publicado en 2014

Identification of type 1 5alpha-reductase in myelin membranes of male and female rat brain

scientific journal article

Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly

artículo científico publicado en 2014

Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases.

artículo científico publicado en 2017

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

artículo científico publicado en 2018

Kinetic properties of the 5 alpha-reductase of testosterone in the purified myelin, in the subcortical white matter and in the cerebral cortex of the male rat brain

artículo científico publicado en 1990

Loss-of-function mutations in the SIGMAR1 gene cause distal hereditary motor neuropathy by impairing ER-mitochondria tethering and Ca2+ signalling

artículo científico publicado en 2016

Luteinizing hormone-releasing hormone agonists interfere with the stimulatory actions of epidermal growth factor in human prostatic cancer cell lines, LNCaP and DU 145

artículo científico publicado en 1996

Modulators of estrogen receptor inhibit proliferation and migration of prostate cancer cells.

artículo científico publicado en 2013

Multiple Roles of Transforming Growth Factor Beta in Amyotrophic Lateral Sclerosis

scientific article published on 16 June 2020

Muscle cells and motoneurons differentially remove mutant SOD1 causing familial amyotrophic lateral sclerosis

artículo científico publicado en 2011

Mutation of SOD1 in ALS: a gain of a loss of function

artículo científico publicado en 2007

Neuritin (cpg15) enhances the differentiating effect of NGF on neuronal PC12 cells

artículo científico publicado en 2007

Neuritin 1 promotes neuronal migration.

artículo científico publicado en 2012

Nuclear Phospho-SOD1 Protects DNA from Oxidative Stress Damage in Amyotrophic Lateral Sclerosis

artículo científico publicado en 2019

Pathological Proteins Are Transported by Extracellular Vesicles of Sporadic Amyotrophic Lateral Sclerosis Patients

artículo científico publicado en 2018

Polyglutamine tract expansion of the androgen receptor in a motoneuronal model of spinal and bulbar muscular atrophy.

artículo científico publicado en 2001

Post-translational modifications of expanded polyglutamine proteins: impact on neurotoxicity.

artículo científico publicado en 2009

Presence of 5alpha-reductase isozymes and aromatase in human prostate cancer cells and in benign prostate hyperplastic tissue.

artículo científico publicado en 1998

Proteasomal and autophagic degradative activities in spinal and bulbar muscular atrophy.

artículo científico publicado en 2010

Publisher Correction: Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.

artículo científico publicado en 2018

Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy

artículo científico publicado en 2017

Searching for the ideal SERM

scientific article published on 01 May 1999

Small heat shock proteins: multifaceted proteins with important implications for life

artículo científico publicado en 2019

Steroid binding and metabolism in the luteinizing hormone-releasing hormone-producing neuronal cell line GT1-1.

artículo científico publicado en 1994

Synergic prodegradative activity of Bicalutamide and trehalose on the mutant androgen receptor responsible for spinal and bulbar muscular atrophy

artículo científico publicado en 2014

Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells

artículo científico publicado en 2018

Testosterone 5 alpha-reductase activity in the rat brain is highly concentrated in white matter structures and in purified myelin sheaths of axons

artículo científico publicado en 1988

Testosterone metabolism in brain cells and membranes

artículo científico publicado en 1991

Testosterone metabolism in peripheral nerves: presence of the 5 alpha-reductase-3 alpha-hydroxysteroid-dehydrogenase enzymatic system in the sciatic nerve of adult and aged rats

artículo científico publicado en 1990

Tetracycline-regulated gene expression in the NSC-34-tTA cell line for investigation of motor neuron diseases.

artículo científico publicado en 2005

The 5 alpha-reductase activity of the subcortical white matter, the cerebral cortex, and the hypothalamus of the rat and of the mouse: possible sex differences and effect of castration

artículo científico publicado en 1987

The Regulation of the Small Heat Shock Protein B8 in Misfolding Protein Diseases Causing Motoneuronal and Muscle Cell Death

artículo científico publicado en 2019

The Role of Sex and Sex Hormones in Neurodegenerative Diseases

artículo científico publicado en 2020

The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.

artículo científico publicado en 2017

The Role of the Protein Quality Control System in SBMA.

artículo científico publicado en 2015

The anabolic/androgenic steroid nandrolone exacerbates gene expression modifications induced by mutant SOD1 in muscles of mice models of amyotrophic lateral sclerosis

artículo científico publicado en 2011

The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits tumor necrosis factor alpha and lipopolysaccharide induced inflammatory response in human endothelial cells and in mice aorta

artículo científico publicado en 2010

The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.

artículo científico publicado en 2016

The growing world of small heat shock proteins: from structure to functions

artículo científico publicado en 2017

The neurotoxicity of mutant proteins 20 years after the discovery of the first mutant gene involved in neurodegeneration. Foreword.

artículo científico publicado en 2012

The polyglutamine tract of androgen receptor: from functions to dysfunctions in motor neurons.

artículo científico publicado en 2004

The protein quality control system in motoneuron diseases

artículo científico publicado en 2015

The role of dynein mediated transport in the clearance of misfolded proteins responsible for motoneuron diseases

artículo científico publicado en 2015

The role of the polyglutamine tract in androgen receptor.

artículo científico publicado en 2007

The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases.

artículo científico publicado en 2017

The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells

artículo científico publicado en 2017

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).

artículo científico publicado en 2010

Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases

artículo científico publicado en 2016

Transforming growth factor beta 1 signaling is altered in the spinal cord and muscle of amyotrophic lateral sclerosis mice and patients

scientific article published on 10 July 2019

Transient Expression of the 5α-Reductase Type 2 Isozyme in the Rat Brain in Late Fetal and Early Postnatal Life1 ⬇️

artículo científico publicado el 1 de abril de 1998

Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration

scientific article published on 05 November 2018

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Angelo Poletti

17-AAG increases autophagic removal of mutant androgen receptor in spinal and bulbar muscular atrophy.

5 alpha-reductase activity in isolated and cultured neuronal and glial cells of the rat.

5 alpha-reductase isozymes in the central nervous system

5alpha-reductase isozymes and aromatase are differentially expressed and active in the androgen-independent human prostate cancer cell lines DU145 and PC3

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.

A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae

A presynaptically toxic secreted phospholipase A2 is internalized into motoneuron-like cells where it is rapidly translocated into the cytosol.

A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases

ALS-related misfolded protein management in motor neurons and muscle cells

Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy.

Aggregation and proteasome: the case of elongated polyglutamine aggregation in spinal and bulbar muscular atrophy.

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins.

Androgen 5-alpha-reductase type 2 is highly expressed and active in rat spinal cord motor neurones

Androgen Metabolism in Different Target Tissues ⬇️

Androgen receptor activation by polychlorinated biphenyls: epigenetic effects mediated by the histone demethylase Jarid1b.

Androgen regulates neuritin mRNA levels in an in vivo model of steroid-enhanced peripheral nerve regeneration

Androgen regulation of axon growth and neurite extension in motoneurons

Androgen-induced neurite outgrowth is mediated by neuritin in motor neurones.

Androgens affect muscle, motor neuron, and survival in a mouse model of SOD1-related amyotrophic lateral sclerosis

Autophagic and Proteasomal Mediated Removal of Mutant Androgen Receptor in Muscle Models of Spinal and Bulbar Muscular Atrophy

BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch.

C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation

CAG repeat length in androgen receptor gene is not associated with amyotrophic lateral sclerosis.

Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy.

Combinatorial treatment for spinal muscular atrophy: An Editorial for 'Combined treatment with the histone deacetylase inhibitor LBH589 and a splice-switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atroph

Concurrent AFG3L2 and SPG7 mutations associated with syndromic parkinsonism and optic atrophy with aberrant OPA1 processing and mitochondrial network fragmentation

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.

Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

Differential autophagy power in the spinal cord and muscle of transgenic ALS mice.

Dihydrotestosterone decreases tumor necrosis factor-alpha and lipopolysaccharide-induced inflammatory response in human endothelial cells.

Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells

Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: implication for protein aggregation and immune response.

Dysregulation of axonal transport and motorneuron diseases.

Effect of postnatal starvation on the 5 alpha-reductase activity of the brain and of the isolated myelin membranes

Effect of suramin on the biological activity of the two isoforms of the rat 5 alpha-reductase

Enhanced Clearance of Neurotoxic Misfolded Proteins by the Natural Compound Berberine and Its Derivatives ⬇️

Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol.

Estrogens, Neuroinflammation, and Neurodegeneration.

Exome sequencing identifies variants in two genes encoding the LIM-proteins NRAP and FHL1 in an Italian patient with BAG3 myofibrillar myopathy.

FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.

Guidelines for the use and interpretation of assays for monitoring autophagy

HSC70 expression is reduced in lymphomonocytes of sporadic ALS patients and contributes to TDP-43 accumulation

Human adipose-derived mesenchymal stem cells as a new model of spinal and bulbar muscular atrophy.

Identification of type 1 5alpha-reductase in myelin membranes of male and female rat brain

Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly

Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases.

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

Kinetic properties of the 5 alpha-reductase of testosterone in the purified myelin, in the subcortical white matter and in the cerebral cortex of the male rat brain

Loss-of-function mutations in the SIGMAR1 gene cause distal hereditary motor neuropathy by impairing ER-mitochondria tethering and Ca2+ signalling

Luteinizing hormone-releasing hormone agonists interfere with the stimulatory actions of epidermal growth factor in human prostatic cancer cell lines, LNCaP and DU 145

Modulators of estrogen receptor inhibit proliferation and migration of prostate cancer cells.

Multiple Roles of Transforming Growth Factor Beta in Amyotrophic Lateral Sclerosis

Muscle cells and motoneurons differentially remove mutant SOD1 causing familial amyotrophic lateral sclerosis

Mutation of SOD1 in ALS: a gain of a loss of function

Neuritin (cpg15) enhances the differentiating effect of NGF on neuronal PC12 cells

Neuritin 1 promotes neuronal migration.

Nuclear Phospho-SOD1 Protects DNA from Oxidative Stress Damage in Amyotrophic Lateral Sclerosis

Pathological Proteins Are Transported by Extracellular Vesicles of Sporadic Amyotrophic Lateral Sclerosis Patients

Polyglutamine tract expansion of the androgen receptor in a motoneuronal model of spinal and bulbar muscular atrophy.

Post-translational modifications of expanded polyglutamine proteins: impact on neurotoxicity.

Presence of 5alpha-reductase isozymes and aromatase in human prostate cancer cells and in benign prostate hyperplastic tissue.

Proteasomal and autophagic degradative activities in spinal and bulbar muscular atrophy.

Publisher Correction: Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.

Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy

Searching for the ideal SERM

Small heat shock proteins: multifaceted proteins with important implications for life

Steroid binding and metabolism in the luteinizing hormone-releasing hormone-producing neuronal cell line GT1-1.

Synergic prodegradative activity of Bicalutamide and trehalose on the mutant androgen receptor responsible for spinal and bulbar muscular atrophy

Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells

Testosterone 5 alpha-reductase activity in the rat brain is highly concentrated in white matter structures and in purified myelin sheaths of axons

Testosterone metabolism in brain cells and membranes

Testosterone metabolism in peripheral nerves: presence of the 5 alpha-reductase-3 alpha-hydroxysteroid-dehydrogenase enzymatic system in the sciatic nerve of adult and aged rats

Tetracycline-regulated gene expression in the NSC-34-tTA cell line for investigation of motor neuron diseases.

The 5 alpha-reductase activity of the subcortical white matter, the cerebral cortex, and the hypothalamus of the rat and of the mouse: possible sex differences and effect of castration

The Regulation of the Small Heat Shock Protein B8 in Misfolding Protein Diseases Causing Motoneuronal and Muscle Cell Death

The Role of Sex and Sex Hormones in Neurodegenerative Diseases

The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.

The Role of the Protein Quality Control System in SBMA.