Lista de obras - Malcolm Lyon - Dominio Público Uruguay

A general method for the detection and mapping of submicrogram quantities of glycosaminoglycan oligosaccharides on polyacrylamide gels by sequential staining with azure A and ammoniacal silver

artículo científico publicado en 1990

A new map of glycosaminoglycan and C3b binding sites on factor H

artículo científico publicado en 2008

A new model for the domain structure of heparan sulfate based on the novel specificity of K5 lyase.

artículo científico publicado en 2004

A rapid purification of bovine testicular hyaluronidase by chromatography on dermatan sulphate-substituted 1,6-diaminohexane--sepharose 4B.

artículo científico publicado en 1981

A simplified and sensitive fluorescent method for disaccharide analysis of both heparan sulfate and chondroitin/dermatan sulfates from biological samples

artículo científico publicado en 2008

An evaluation of cytosolic erythrocyte carbonic anhydrase and catalase in carcinoma patients: An elevation of carbonic anhydrase activity

artículo científico publicado en 2006

Binding of endostatin to endothelial heparan sulphate shows a differential requirement for specific sulphates.

artículo científico publicado en 2003

Binding of perlecan to transthyretin qin vitro ⬇️

artículo científico publicado el 15 de septiembre de 1997

Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion

scientific article published on 01 November 1998

Characterization and binding activity of the chondroitin/dermatan sulfate chain from Endocan, a soluble endothelial proteoglycan

artículo científico publicado en 2010

Conformation of glycosaminoglycans by ion mobility mass spectrometry and molecular modelling

artículo científico publicado en 2005

DMT-MM mediated functionalisation of the non-reducing end of glycosaminoglycans

artículo científico publicado en 2007

Determination of the Disaccharide Composition of Glycosaminoglycans: Comparison of Chemical and Enzymatic Scission

article

Disease-associated sequence variations congregate in a polyanion recognition patch on human factor H revealed in three-dimensional structure

artículo científico publicado en 2006

Distinct substrate specificities of bacterial heparinases against N-unsubstituted glucosamine residues in heparan sulfate

artículo científico publicado en 2005

Elucidation of the structural features of heparan sulfate important for interaction with the Hep-2 domain of fibronectin.

artículo científico

Endocan or endothelial cell specific molecule-1 (ESM-1): a potential novel endothelial cell marker and a new target for cancer therapy.

artículo científico publicado en 2005

Fibroblast Growth Factor-2 Stimulation of p42/44MAPKPhosphorylation and IκB Degradation Is Regulated by Heparan Sulfate/Heparin in Rat Mammary Fibroblasts

artículo científico publicado en 2000

HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

artículo científico publicado en 2006

Heparan Sulfate

Heparan sulfate undergoes specific structural changes during the progression from human colon adenoma to carcinoma in vitro

artículo científico publicado en 1998

Heparan sulphate-degrading endoglycosidase in liver plasma membranes ⬇️

artículo científico publicado en 1988

Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes

artículo científico publicado en 2002

Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfate

artículo científico publicado en 1998

Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways.

artículo científico publicado en 2001

Hepatocyte growth factor/scatter factor: a heparan sulphate-binding pleiotropic growth factor

scientific article published on 01 May 1994

Highly sensitive sequencing of the sulfated domains of heparan sulfate.

artículo científico publicado en 1999

Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains

artículo científico publicado en 2007

Interaction of human β-defensin 2 (HBD2) with glycosaminoglycans.

artículo científico publicado en 2010

Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density.

artículo científico publicado en 2007

Isolation and characterization of high-buoyant-density proteoglycans from bovine femoral-head cartilage.

artículo científico publicado en 1983

Isolation and characterization of the integral glycosaminoglycan constituents of human amyloid A and monoclonal light-chain amyloid fibrils.

artículo científico publicado en 1991

Lysine and arginine side chains in glycosaminoglycan-protein complexes investigated by NMR, cross-linking, and mass spectrometry: a case study of the factor H-heparin interaction.

artículo científico

Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration

artículo científico publicado en 2009

Novel heparin/heparan sulfate mimics as inhibitors of HGF/SF-induced MET activation

artículo científico publicado en 2007

Patterns of sulphation in heparan sulphate: polymorphism based on a common structural theme

scientific article (publication date: April 1992)

Preparation of heparin/heparan sulfate oligosaccharides with internal N-unsubstituted glucosamine residues for functional studies

artículo científico publicado en 2011

Proteoglycans

Proteoglycans of human T lymphocytes: differences between helper and suppressor subsets

article

Purification and partial characterization of the major cell-associated heparan sulphate proteoglycan of rat liver ⬇️

artículo científico publicado el 15 de enero de 1991

Quantitative and qualitative alterations of heparan sulfate in fibrogenic liver diseases and hepatocellular cancer

artículo científico publicado en 2010

Residual dipolar coupling investigation of a heparin tetrasaccharide confirms the limited effect of flexibility of the iduronic acid on the molecular shape of heparin

artículo científico publicado en 2009

Specific chemical modifications of link protein and their effect on binding to hyaluronate and cartilage proteoglycan

artículo científico publicado en 1986

Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism

artículo científico publicado en 2007

The binding properties of minimal oligosaccharides reveal a common heparan sulfate/dermatan sulfate-binding site in hepatocyte growth factor/scatter factor that can accommodate a wide variety of sulfation patterns

artículo científico publicado en 2008

The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue.

artículo científico publicado en 2007

The interaction of the transforming growth factor-betas with heparin/heparan sulfate is isoform-specific.

artículo científico publicado en 1997

The interactions of hepatocyte growth factor/scatter factor and its NK1 and NK2 variants with glycosaminoglycans using a modified gel mobility shift assay. Elucidation of the minimal size of binding and activatory oligosaccharides

artículo científico publicado en 2004

The isolation of membrane proteoglycans

artículo científico publicado en 1993

The mode of action of heparan and dermatan sulfates in the regulation of hepatocyte growth factor/scatter factor

artículo científico publicado en 2002

The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse

scientific journal article

The synthesis of proteoglycans by human T lymphocytes

artículo científico publicado en 1990

Lista de obras de Malcolm Lyon

A general method for the detection and mapping of submicrogram quantities of glycosaminoglycan oligosaccharides on polyacrylamide gels by sequential staining with azure A and ammoniacal silver

A new map of glycosaminoglycan and C3b binding sites on factor H

A new model for the domain structure of heparan sulfate based on the novel specificity of K5 lyase.

A rapid purification of bovine testicular hyaluronidase by chromatography on dermatan sulphate-substituted 1,6-diaminohexane--sepharose 4B.

A simplified and sensitive fluorescent method for disaccharide analysis of both heparan sulfate and chondroitin/dermatan sulfates from biological samples

An evaluation of cytosolic erythrocyte carbonic anhydrase and catalase in carcinoma patients: An elevation of carbonic anhydrase activity

Binding of endostatin to endothelial heparan sulphate shows a differential requirement for specific sulphates.

Binding of perlecan to transthyretin qin vitro ⬇️

Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion

Characterization and binding activity of the chondroitin/dermatan sulfate chain from Endocan, a soluble endothelial proteoglycan

Conformation of glycosaminoglycans by ion mobility mass spectrometry and molecular modelling

DMT-MM mediated functionalisation of the non-reducing end of glycosaminoglycans

Determination of the Disaccharide Composition of Glycosaminoglycans: Comparison of Chemical and Enzymatic Scission

Disease-associated sequence variations congregate in a polyanion recognition patch on human factor H revealed in three-dimensional structure

Distinct substrate specificities of bacterial heparinases against N-unsubstituted glucosamine residues in heparan sulfate

Elucidation of the structural features of heparan sulfate important for interaction with the Hep-2 domain of fibronectin.

Endocan or endothelial cell specific molecule-1 (ESM-1): a potential novel endothelial cell marker and a new target for cancer therapy.

Fibroblast Growth Factor-2 Stimulation of p42/44MAPKPhosphorylation and IκB Degradation Is Regulated by Heparan Sulfate/Heparin in Rat Mammary Fibroblasts

HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

Heparan Sulfate

Heparan sulfate undergoes specific structural changes during the progression from human colon adenoma to carcinoma in vitro

Heparan sulphate-degrading endoglycosidase in liver plasma membranes ⬇️

Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes

Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfate

Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways.

Hepatocyte growth factor/scatter factor: a heparan sulphate-binding pleiotropic growth factor

Highly sensitive sequencing of the sulfated domains of heparan sulfate.

Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains

Interaction of human β-defensin 2 (HBD2) with glycosaminoglycans.

Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density.

Isolation and characterization of high-buoyant-density proteoglycans from bovine femoral-head cartilage.

Isolation and characterization of the integral glycosaminoglycan constituents of human amyloid A and monoclonal light-chain amyloid fibrils.

Lysine and arginine side chains in glycosaminoglycan-protein complexes investigated by NMR, cross-linking, and mass spectrometry: a case study of the factor H-heparin interaction.

Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration

Novel heparin/heparan sulfate mimics as inhibitors of HGF/SF-induced MET activation

Patterns of sulphation in heparan sulphate: polymorphism based on a common structural theme

Preparation of heparin/heparan sulfate oligosaccharides with internal N-unsubstituted glucosamine residues for functional studies

Proteoglycans

Proteoglycans of human T lymphocytes: differences between helper and suppressor subsets

Purification and partial characterization of the major cell-associated heparan sulphate proteoglycan of rat liver ⬇️

Quantitative and qualitative alterations of heparan sulfate in fibrogenic liver diseases and hepatocellular cancer

Residual dipolar coupling investigation of a heparin tetrasaccharide confirms the limited effect of flexibility of the iduronic acid on the molecular shape of heparin

Specific chemical modifications of link protein and their effect on binding to hyaluronate and cartilage proteoglycan

Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism

The binding properties of minimal oligosaccharides reveal a common heparan sulfate/dermatan sulfate-binding site in hepatocyte growth factor/scatter factor that can accommodate a wide variety of sulfation patterns

The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue.

The interaction of the transforming growth factor-betas with heparin/heparan sulfate is isoform-specific.

The interactions of hepatocyte growth factor/scatter factor and its NK1 and NK2 variants with glycosaminoglycans using a modified gel mobility shift assay. Elucidation of the minimal size of binding and activatory oligosaccharides

The isolation of membrane proteoglycans

The mode of action of heparan and dermatan sulfates in the regulation of hepatocyte growth factor/scatter factor

The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse

The synthesis of proteoglycans by human T lymphocytes