Lista de obras - Robert J. Geraghty - Dominio Público Uruguay

4,7-Disubstituted 7H-Pyrrolo[2,3-d]pyrimidines and Their Analogs as Antiviral Agents against Zika Virus

artículo científico publicado en 2021

5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus

artículo científico publicado en 2015

A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and pseudorabies virus

artículo científico publicado en 1998

A fluorescence-based high-throughput assay to identify inhibitors of tyrosylprotein sulfotransferase activity.

artículo científico publicado en 2016

A virus-binding hot spot on human angiotensin-converting enzyme 2 is critical for binding of two different coronaviruses

artículo científico publicado en 2011

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus

artículo científico publicado en 2012

Cell type-dependence for Vpu function

artículo científico publicado en 1994

Cellular expression of alphaherpesvirus gD interferes with entry of homologous and heterologous alphaherpesviruses by blocking access to a shared gD receptor

artículo científico publicado en 2000

Contributions of gD receptors and glycosaminoglycan sulfation to cell fusion mediated by herpes simplex virus 1.

artículo científico publicado en 2001

Design and synthesis of an activity-based protein profiling probe derived from cinnamic hydroxamic acid.

artículo científico publicado en 2015

Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor

artículo científico publicado en 1998

FRET-based assay using a three-way junction DNA substrate to identify inhibitors of human cytomegalovirus pUL89 endonuclease activity

scientific article published on 17 October 2018

Fluorescent peptide sensors for tyrosylprotein sulfotransferase activity

artículo científico publicado en 2014

Fusion activity of lipid-anchored envelope glycoproteins of herpes simplex virus type 1.

artículo científico publicado en 2004

HIV-1 particle release mediated by Vpu is distinct from that mediated by p6.

artículo científico publicado en 1996

Herpes Simplex Virus Glycoprotein D Can Bind to Poliovirus Receptor-Related Protein 1 or Herpesvirus Entry Mediator, Two Structurally Unrelated Mediators of Virus Entry ⬇️

artículo científico publicado el 1 de septiembre de 1998

Herpes simplex virus type 1 glycoprotein L mutants that fail to promote trafficking of glycoprotein H and fail to function in fusion can induce binding of glycoprotein L-dependent anti-glycoprotein H antibodies

artículo científico publicado en 2006

Herpes simplex virus type 1 mediates fusion through a hemifusion intermediate by sequential activity of glycoproteins D, H, L, and B

artículo científico publicado en 2007

Hydroxamic acids block replication of hepatitis C virus

artículo científico publicado en 2014

Hydroxypyridonecarboxylic Acids as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease

artículo científico publicado en 2018

Inhibition of Human Cytomegalovirus pUL89 Terminase Subunit Blocks Virus Replication and Genome Cleavage

artículo científico publicado en 2016

Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus

artículo científico publicado en 2012

Metal-chelating 3-hydroxypyrimidine-2,4-diones inhibit human cytomegalovirus pUL89 endonuclease activity and virus replication.

artículo científico publicado en 2018

Mutagenic analysis of herpes simplex virus type 1 glycoprotein L reveals the importance of an arginine-rich region for function.

artículo científico publicado en 2008

Mutations in the amino terminus of herpes simplex virus type 1 gL can reduce cell-cell fusion without affecting gH/gL trafficking.

artículo científico publicado en 2013

Nucleobases and corresponding nucleosides display potent antiviral activities against dengue virus possibly through viral lethal mutagenesis

artículo científico publicado en 2018

One-Pot Synthesis of 1-Hydroxyacridones from para-Quinols and ortho-Methoxycarbonylaryl Isocyanates

scientific article published on 27 February 2020

Structure activity relationship, 6-modified purine riboside analogues to activate hSTING, stimulator of interferon genes

artículo científico publicado en 2019

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus ⬇️

artículo científico publicado el 24 de octubre de 2011

The nectin-1alpha transmembrane domain, but not the cytoplasmic tail, influences cell fusion induced by HSV-1 glycoproteins.

artículo científico publicado en 2005

Use of chimeric nectin-1(HveC)-related receptors to demonstrate that ability to bind alphaherpesvirus gD is not necessarily sufficient for viral entry

scientific article published on 01 July 2001

Zika Virus Inhibitors Based on a 1,3-Disubstituted 1H-Pyrazolo[3,4-d]pyrimidine-amine Scaffold

artículo científico publicado en 2022

Lista de obras de Robert J. Geraghty

4,7-Disubstituted 7H-Pyrrolo[2,3-d]pyrimidines and Their Analogs as Antiviral Agents against Zika Virus

5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus

A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and pseudorabies virus

A fluorescence-based high-throughput assay to identify inhibitors of tyrosylprotein sulfotransferase activity.

A virus-binding hot spot on human angiotensin-converting enzyme 2 is critical for binding of two different coronaviruses

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus

Cell type-dependence for Vpu function

Cellular expression of alphaherpesvirus gD interferes with entry of homologous and heterologous alphaherpesviruses by blocking access to a shared gD receptor

Contributions of gD receptors and glycosaminoglycan sulfation to cell fusion mediated by herpes simplex virus 1.

Design and synthesis of an activity-based protein profiling probe derived from cinnamic hydroxamic acid.

Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor

FRET-based assay using a three-way junction DNA substrate to identify inhibitors of human cytomegalovirus pUL89 endonuclease activity

Fluorescent peptide sensors for tyrosylprotein sulfotransferase activity

Fusion activity of lipid-anchored envelope glycoproteins of herpes simplex virus type 1.

HIV-1 particle release mediated by Vpu is distinct from that mediated by p6.

Herpes Simplex Virus Glycoprotein D Can Bind to Poliovirus Receptor-Related Protein 1 or Herpesvirus Entry Mediator, Two Structurally Unrelated Mediators of Virus Entry ⬇️

Herpes simplex virus type 1 glycoprotein L mutants that fail to promote trafficking of glycoprotein H and fail to function in fusion can induce binding of glycoprotein L-dependent anti-glycoprotein H antibodies

Herpes simplex virus type 1 mediates fusion through a hemifusion intermediate by sequential activity of glycoproteins D, H, L, and B

Hydroxamic acids block replication of hepatitis C virus

Hydroxypyridonecarboxylic Acids as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease

Inhibition of Human Cytomegalovirus pUL89 Terminase Subunit Blocks Virus Replication and Genome Cleavage

Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus

Metal-chelating 3-hydroxypyrimidine-2,4-diones inhibit human cytomegalovirus pUL89 endonuclease activity and virus replication.

Mutagenic analysis of herpes simplex virus type 1 glycoprotein L reveals the importance of an arginine-rich region for function.

Mutations in the amino terminus of herpes simplex virus type 1 gL can reduce cell-cell fusion without affecting gH/gL trafficking.

Nucleobases and corresponding nucleosides display potent antiviral activities against dengue virus possibly through viral lethal mutagenesis

One-Pot Synthesis of 1-Hydroxyacridones from para-Quinols and ortho-Methoxycarbonylaryl Isocyanates

Structure activity relationship, 6-modified purine riboside analogues to activate hSTING, stimulator of interferon genes

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus ⬇️

The nectin-1alpha transmembrane domain, but not the cytoplasmic tail, influences cell fusion induced by HSV-1 glycoproteins.

Use of chimeric nectin-1(HveC)-related receptors to demonstrate that ability to bind alphaherpesvirus gD is not necessarily sufficient for viral entry

Zika Virus Inhibitors Based on a 1,3-Disubstituted 1H-Pyrazolo[3,4-d]pyrimidine-amine Scaffold