Lista de obras - Salvatore Guccione - Dominio Público Uruguay

3D-QSAR using 'multiconformer' alignment: the use of HASL in the analysis of 5-HT1A thienopyrimidinone ligands

scientific article published on 01 October 2000

4-Methyl-2-[N-(3,4-methylenedioxybenzylidene)hydrazino]thiazole and its reduction product, 4-methyl-2-[N-(3,4-methylenedioxybenzylidene)hydrazono]-4,5-dihydrothiazole.

artículo científico publicado en 2002

Building a model of interaction at the NK-2 receptors: Polycondensed heterocycles containing the pyrimidoindole skeleton

Combined NMR-crystallographic and modelling investigation of the inclusion of molsidomine into alpha-, beta- and gamma-cyclodextrins.

artículo científico publicado en 2005

Combining NMR and molecular modelling in a drug delivery context: investigation of the multi-mode inclusion of a new NPY-5 antagonist bromobenzenesulfonamide into beta-cyclodextrin

artículo científico publicado en 2004

Combining molecular modeling with experimental methodologies: mechanism of membrane permeation and accumulation of ofloxacin

artículo científico publicado en 2002

Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

Correction to Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

scholarly article published in Journal of Chemical Information and Modeling

Design, synthesis and binding properties of novel and selective 5-HT(3) and 5-HT(4) receptor ligands

artículo científico publicado en 2000

Design, synthesis and binding properties of novel and selective 5-HT3 and 5-HT4 receptor ligands

artículo científico publicado en 2001

Emerging antifungal azoles and effects on Magnaporthe grisea.

artículo científico publicado en 2006

Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids. I. Synthesis and biological evaluation of lipophilic conjugates of tranylcypromine

artículo científico publicado en 2005

Evaluation of imidazole-based compounds as heme oxygenase-1 inhibitors

artículo científico publicado en 2012

Heme oxygenase-2/adiponectin protein-protein interaction in metabolic syndrome.

artículo científico publicado en 2013

How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling.

artículo científico publicado en 2015

How to Choose the Suitable Template for Homology Modelling of GPCRs: 5-HT7 Receptor as a Test Case.

artículo científico publicado en 2016

Hydrophobic molecular similarity from MST fractional contributions to the octanol/water partition coefficient.

artículo científico publicado en 2005

Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity.

artículo científico publicado en 2015

Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis

artículo científico publicado en 2015

Interactions of imidazoline ligands with the active site of purified monoamine oxidase A

artículo científico publicado en 2007

Lipophilic conjugates of methotrexate with short-chain alkylamino acids as DHFR inhibitors. Synthesis, biological evaluation, and molecular modeling.

artículo científico publicado en 2004

Molecular properties of ibuprofen and its solid dispersions with Eudragit RL100 studied by solid-state nuclear magnetic resonance

artículo científico publicado en 2005

Multiconformational Method for Analyzing the Biological Activity of Molecular Structures

Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity.

artículo científico publicado en 2015

Novel Benzo[b]thiophene Derivatives as New Potential Antidepressants with Rapid Onset of Action

artículo científico publicado en 2011

Parameters for Irreversible Inactivation of Monoamine Oxidase

scientific article published on 13 December 2020

Pharmacological properties and biochemical mechanisms of μ-opioid receptor ligands might be due to different binding poses: MD Studies

scientific article published on 25 September 2020

Potential immunoregulatory role of heme oxygenase-1 in human milk: a combined biochemical and molecular modeling approach.

artículo científico publicado en 2009

Potential of aryl–urea–benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease

artículo científico publicado en 2015

Preparation, characterisation and photosensitivity studies of solid dispersions of diflunisal and Eudragit RS100 and RL100.

artículo científico publicado en 2001

Sequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonism

artículo científico publicado en 2014

Spectroscopic Investigation and Molecular Modeling on Porphyrin/PAMAM Supramolecular Adduct

Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases

scientific article published on 29 March 2006

Sulfonilamidothiopyrimidone and thiopyrimidone derivatives as selective COX-2 inhibitors: Synthesis, biological evaluation, and docking studies

artículo científico publicado en 2012

Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors

artículo científico publicado en 2002

Synthesis, benzodiazepine receptor binding and molecular modelling of isochromeno[4,3-c]pyrazol-5(1H)-one derivatives.

artículo científico publicado en 2012

TCP-FA4: a derivative of tranylcypromine showing improved blood-brain permeability.

artículo científico publicado en 2009

The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development.

scientific article published on January 2008

Theoretical calculations of the catalytic triad in short-chain alcohol dehydrogenases/reductases

artículo científico publicado en 2007

Lista de obras de Salvatore Guccione

3D-QSAR using 'multiconformer' alignment: the use of HASL in the analysis of 5-HT1A thienopyrimidinone ligands

4-Methyl-2-[N-(3,4-methylenedioxybenzylidene)hydrazino]thiazole and its reduction product, 4-methyl-2-[N-(3,4-methylenedioxybenzylidene)hydrazono]-4,5-dihydrothiazole.

Building a model of interaction at the NK-2 receptors: Polycondensed heterocycles containing the pyrimidoindole skeleton

Combined NMR-crystallographic and modelling investigation of the inclusion of molsidomine into alpha-, beta- and gamma-cyclodextrins.

Combining NMR and molecular modelling in a drug delivery context: investigation of the multi-mode inclusion of a new NPY-5 antagonist bromobenzenesulfonamide into beta-cyclodextrin

Combining molecular modeling with experimental methodologies: mechanism of membrane permeation and accumulation of ofloxacin

Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

Correction to Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

Design, synthesis and binding properties of novel and selective 5-HT(3) and 5-HT(4) receptor ligands

Design, synthesis and binding properties of novel and selective 5-HT3 and 5-HT4 receptor ligands

Emerging antifungal azoles and effects on Magnaporthe grisea.

Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids. I. Synthesis and biological evaluation of lipophilic conjugates of tranylcypromine

Evaluation of imidazole-based compounds as heme oxygenase-1 inhibitors

Heme oxygenase-2/adiponectin protein-protein interaction in metabolic syndrome.

How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling.

How to Choose the Suitable Template for Homology Modelling of GPCRs: 5-HT7 Receptor as a Test Case.

Hydrophobic molecular similarity from MST fractional contributions to the octanol/water partition coefficient.

Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity.

Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis

Interactions of imidazoline ligands with the active site of purified monoamine oxidase A

Lipophilic conjugates of methotrexate with short-chain alkylamino acids as DHFR inhibitors. Synthesis, biological evaluation, and molecular modeling.

Molecular properties of ibuprofen and its solid dispersions with Eudragit RL100 studied by solid-state nuclear magnetic resonance

Multiconformational Method for Analyzing the Biological Activity of Molecular Structures

Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity.

Novel Benzo[b]thiophene Derivatives as New Potential Antidepressants with Rapid Onset of Action

Parameters for Irreversible Inactivation of Monoamine Oxidase

Pharmacological properties and biochemical mechanisms of μ-opioid receptor ligands might be due to different binding poses: MD Studies

Potential immunoregulatory role of heme oxygenase-1 in human milk: a combined biochemical and molecular modeling approach.

Potential of aryl–urea–benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease

Preparation, characterisation and photosensitivity studies of solid dispersions of diflunisal and Eudragit RS100 and RL100.

Sequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonism

Spectroscopic Investigation and Molecular Modeling on Porphyrin/PAMAM Supramolecular Adduct

Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases

Sulfonilamidothiopyrimidone and thiopyrimidone derivatives as selective COX-2 inhibitors: Synthesis, biological evaluation, and docking studies

Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors

Synthesis, benzodiazepine receptor binding and molecular modelling of isochromeno[4,3-c]pyrazol-5(1H)-one derivatives.

TCP-FA4: a derivative of tranylcypromine showing improved blood-brain permeability.

The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development.

Theoretical calculations of the catalytic triad in short-chain alcohol dehydrogenases/reductases

Unforeseen alkylating effect of triethylorthoformate in the synthesis of pyrazolotriazolopyrimidine derivative