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Lista de obras de Wei-Guo Zhu

5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins

artículo científico publicado en 2011

5-Fluorouracil targets histone acetyltransferases p300/CBP in the treatment of colorectal cancer.

artículo científico publicado en 2017

5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation.

artículo científico publicado en 2004

A SIRT1-centered circuitry regulates breast cancer stemness and metastasis

artículo científico publicado en 2018

A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes.

artículo científico publicado en 2003

A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells

artículo científico publicado en 2017

ATM-mediated KDM2A phosphorylation is required for the DNA damage repair.

artículo científico publicado en 2015

Acetylation of 53BP1 dictates the DNA double strand break repair pathway.

artículo científico publicado en 2017

Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A

scientific article published on 01 May 2019

Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1).

artículo científico publicado en 2006

Advances in effector protein of histone methylation

artículo científico publicado en 2011

Advances in histone methyltransferases and histone demethylases

article

An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment

artículo científico

Angiotensin II reduces cardiac AdipoR1 expression through AT1 receptor/ROS/ERK1/2/c-Myc pathway

scientific journal article

Anti-neoplastic activity of the cytosolic FoxO1 results from autophagic cell death.

artículo científico publicado en 2010

Applications of post-translational modifications of FoxO family proteins in biological functions ⬇️

artículo científico publicado el 13 de junio de 2011

Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62.

artículo científico publicado en 2016

Autophagy process is associated with anti-neoplastic function.

scientific article published on 26 April 2011

Autophagy regulates DNA repair by modulating histone ubiquitination

artículo científico publicado en 2016

Autophagy substrate SQSTM1/p62 regulates chromatin ubiquitination during the DNA damage response

artículo científico publicado en 2016

Autophagy-deficient tumor cells rely on extracellular amino acids to survive upon glutamine deprivation

scientific article published on 04 August 2018

Biological function and regulation of histone and non-histone lysine methylation in response to DNA damage.

artículo científico publicado en 2016

Bone morphogenetic protein 3B silencing in non-small-cell lung cancer.

artículo científico publicado en 2004

C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex

scientific article published on 25 July 2019

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

artículo científico publicado en 2010

DNA Methylation in the Exon 1 Region and Complex Regulation of Twist1 Expression in Gastric Cancer Cells

artículo científico publicado en 2015

DNA damage and repair

artículo científico publicado en 2005

DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors.

artículo científico publicado en 2001

DNA methyltransferases: the role in regulation of gene expression and biological processes

article

Deficiency of hepatocystin induces autophagy through an mTOR-dependent pathway

artículo científico publicado en 2011

Dependence of induction of interphase death of Chinese hamster ovary cells exposed to accelerated heavy ions on linear energy transfer

article

Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair

artículo científico publicado en 2018

Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer

artículo científico publicado en 2017

EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin.

artículo científico publicado en 2011

Enhancement of hyperthermic killing in L5178Y cells by protease inhibitors

artículo científico publicado en 1995

Epigenetic modification of PKMζ rescues aging-related cognitive impairment.

artículo científico publicado en 2016

Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway

scientific journal article

Erratum: ATM-mediated KDM2A phosphorylation is required for the DNA damage repair

artículo científico publicado en 2016

Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer.

artículo científico publicado en 2004

FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway.

artículo científico publicado en 2012

Global methylation profiling of lung cancer identifies novel methylated genes

artículo científico publicado en 2001

Glucose-derived acetate and ACSS2 as key players in cisplatin resistance in bladder cancer

artículo científico publicado en 2018

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells

artículo científico publicado en 2008

HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration

scientific article published on 01 April 2020

Heat-induced modulation of lamin B content in two different cell lines

artículo científico publicado en 1999

Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter.

artículo científico publicado en 2008

Histone modifications in DNA damage response

artículo científico publicado en 2016

Identifying Human SIRT1 Substrates by Integrating Heterogeneous Information from Various Sources.

artículo científico publicado en 2017

Increased Amino Acid Uptake Supports Autophagy-Deficient Cell Survival upon Glutamine Deprivation

artículo científico publicado en 2018

Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells

artículo científico publicado en 2001

Kindlin 2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signalling

artículo científico publicado en 2012

Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model

artículo científico publicado en 2019

Lamin B is a prompt heat shock protein

artículo científico publicado en 1999

Linker Histone in Diseases.

artículo científico publicado en 2017

Long-term tumor resistance induced by laser photo-immunotherapy.

artículo científico publicado en 1999

Loss of FOXO1 Cooperates with TMPRSS2-ERG Overexpression to Promote Prostate Tumorigenesis and Cell Invasion

artículo científico publicado en 2017

Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice

artículo científico publicado en 2002

MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent manner

scientific article published on 07 December 2018

Mechanism of regulating deacetylase SIRT1 expression and activity

artículo científico publicado en 2010

Mechanisms controlling the anti-neoplastic functions of FoxO proteins.

artículo científico publicado en 2017

Methylation of FoxO3 regulates neuronal cell death ⬇️

artículo científico publicado el 1 de mayo de 2012

Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability

artículo científico publicado en 2013

Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter

artículo científico publicado en 2003

Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1).

artículo científico publicado en 2011

Molecular mechanisms of epigenetic regulators as activatable targets in cancer theranostics

artículo científico publicado en 2017

Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1.

artículo científico publicado en 2006

P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells.

artículo científico publicado en 2003

PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6.

artículo científico publicado en 2016

PCAF/GCN5-Mediated Acetylation of RPA1 Promotes Nucleotide Excision Repair

artículo científico publicado en 2017

PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment

artículo científico publicado en 2017

Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release

scientific article published on 30 January 2013

Phosphorylation of LSD1 by PLK1 promotes its chromatin release during mitosis.

scientific article published on 23 March 2017

Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53

artículo científico publicado en 2007

Post-irradiation exposure to HBSS enhances apoptosis in FM3A cells.

artículo científico publicado en 1998

Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2

scientific journal article

Promotion of Heat-Induced Apoptosis in FM3A Cells by Protease Inhibitors

artículo científico publicado en 1996

Quantitative proteome-based systematic identification of SIRT7 substrates.

artículo científico publicado en 2017

RT-PCR heteroduplex analysis permits differentiation of transgene and host gene expression in a transgenic animal model

article

Reduced expression of SET7/9, a histone mono-methyltransferase, is associated with gastric cancer progression

artículo científico publicado en 2015

Regulation of histone acetyltransferase TIP60 function by histone deacetylase 3.

artículo científico publicado en 2014

Regulation of p53 acetylation

Reply to Leithner et al.: Focus on phopshoenolpyruvate carboxykinase (PEPCK): a target of the p53-SIRT6-FoxO1 axis

artículo científico publicado en 2014

SET7/9 regulates cancer cell proliferation by influencing β-catenin stability

artículo científico publicado en 2015

SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation.

artículo científico publicado en 2017

SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism

scientific article published on 17 May 2019

SIRT4 regulates PTEN stability through IDE in response to cellular stresses

scientific article published on 16 January 2019

SIRT5, functions in cellular metabolism with a multiple enzymatic activities

artículo científico publicado en 2015

SIRT6 coordinates with CHD4 to promote chromatin relaxation and DNA repair

artículo científico publicado en 2020

SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis

artículo científico publicado en 2017

SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair

artículo científico publicado en 2019

Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins

artículo científico publicado en 2017

Sirtuin 7-mediated deacetylation of WD repeat domain 77 (WDR77) suppresses cancer cell growth by reducing WDR77/PRMT5 transmethylase complex activity

artículo científico publicado en 2018

Sirtuins in glucose and lipid metabolism.

artículo científico publicado en 2017

Sirtuins: Nodes Connecting Aging, Metabolism and Tumorigenesis ⬇️

artículo científico publicado el 1 de enero de 2014

Surf the post-translational modification network of p53 regulation

artículo científico publicado en 2012

Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice

artículo científico publicado en 2020

Systematic identification of Class I HDAC substrates.

artículo científico publicado en 2013

Targeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implications

artículo científico publicado en 2014

The Batten disease gene CLN3 confers resistance to endoplasmic reticulum stress induced by tunicamycin.

artículo científico publicado en 2014

The HDAC inhibitor depsipeptide transactivates the p53/p21 pathway by inducing DNA damage.

artículo científico publicado en 2011

The axis of MAPK1/3-XBP1u-FOXO1 controls autophagic dynamics in cancer cells ⬇️

artículo científico publicado el 20 de febrero de 2013

The changing face of HDAC inhibitor depsipeptide.

artículo científico publicado en 2009

The expression of chemokine receptors CXCR3 and CXCR4 in predicting postoperative tumour progression in stages I-II colon cancer: a retrospective study.

artículo científico publicado en 2014

The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells.

artículo científico publicado en 2003

The regulation of the autophagic network and its implications for human disease

artículo científico publicado en 2013

The role of histone acetyltransferase Tip60 in transcription and DNA damage response

artículo científico publicado en 2011

The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2

artículo científico publicado en 2015

Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses

artículo científico publicado en 2010

Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion.

artículo científico publicado en 2014

ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint

artículo científico publicado en 2019

Ubiquitin-like modifications in the DNA damage response

artículo científico publicado en 2017

Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis

artículo científico publicado en 2017

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

artículo científico publicado en 2013

ZD6474 induces growth arrest and apoptosis of GIST-T1 cells, which is enhanced by concomitant use of sunitinib

article

p53 cooperates with SIRT6 to regulate cardiolipin de novo biosynthesis

artículo científico publicado en 2018

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

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