Lista de obras - Ruud F Toonen - Dominio Público Uruguay

A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons

scientific article published on 01 May 2019

A closer look at FBXO41 as a Parkinson's disease risk factor

scientific article published on 06 September 2013

Automated analysis of neuronal morphology, synapse number and synaptic recruitment

artículo científico publicado en 2010

Automated quantification of cellular traffic in living cells.

artículo científico publicado en 2008

CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons

scientific journal article

CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons

artículo científico publicado en 2017

Ca(2+)-induced recruitment of the secretory vesicle protein DOC2B to the target membrane.

artículo científico publicado en 2004

CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles

artículo científico publicado en 2020

Correction: Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

artículo científico publicado en 2018

Crashpilot Underachieves due to Acetylation at the Nerve Terminal ⬇️

artículo científico publicado el 8 de diciembre de 2011

Deletion of Munc18-1 in 5-HT neurons results in rapid degeneration of the 5-HT system and early postnatal lethality.

artículo científico publicado en 2011

Dendritic position is a major determinant of presynaptic strength.

artículo científico publicado en 2012

Dense-core vesicle biogenesis and exocytosis in neurons lacking chromogranins A and B.

artículo científico publicado en 2017

Detection of silent cells, synchronization and modulatory activity in developing cellular networks

artículo científico publicado en 2015

Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons.

artículo científico publicado en 2017

Dissecting docking and tethering of secretory vesicles at the target membrane.

artículo científico publicado en 2006

Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25.

artículo científico publicado en 2017

Fbxo41 Promotes Disassembly of Neuronal Primary Cilia

artículo científico publicado en 2019

Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences

artículo científico publicado en 2015

Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.

artículo científico publicado en 2011

Homozygous STXBP1 variant causes encephalopathy and gain-of-function in synaptic transmission

artículo científico publicado en 2020

Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticity

artículo científico publicado en 2007

Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission

artículo científico publicado en 2013

Matrix-dependent local retention of secretory vesicle cargo in cortical neurons

artículo científico publicado en 2009

Multi-level characterization of balanced inhibitory-excitatory cortical neuron network derived from human pluripotent stem cells.

artículo científico publicado en 2017

Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles

artículo científico publicado en 2017

Munc18-1 expression levels control synapse recovery by regulating readily releasable pool size

scientific journal article

Munc18-1 in secretion: lonely Munc joins SNARE team and takes control.

artículo científico publicado en 2007

Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release

artículo científico publicado en 2014

Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission.

artículo científico publicado en 2012

Munc18-1 phosphorylation by protein kinase C potentiates vesicle pool replenishment in bovine chromaffin cells.

artículo científico publicado en 2006

Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming.

artículo científico publicado en 2007

Phosphorylation of synaptotagmin-1 controls a post-priming step in PKC-dependent presynaptic plasticity

artículo científico publicado en 2016

Pool size estimations for dense-core vesicles in mammalian CNS neurons

scientific article published on 05 September 2018

Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1.

artículo científico publicado en 2016

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

artículo científico publicado en 2018

Regulated exocytosis: merging ideas on fusing membranes.

artículo científico publicado en 2007

SALM1 controls synapse development by promoting F-actin/PIP2-dependent Neurexin clustering

scientific article published on 01 August 2019

SNAP-25 gene family members differentially support secretory vesicle fusion.

artículo científico publicado en 2017

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

artículo científico publicado en 2019

Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.

artículo científico publicado en 2012

Synaptic Effects of Munc18-1 Alternative Splicing in Excitatory Hippocampal Neurons

artículo científico publicado en 2015

The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators

scientific article published on 31 October 2019

The role of Rab3a in secretory vesicle docking requires association/dissociation of guanidine phosphates and Munc18-1.

artículo científico publicado en 2007

Tyrosine phosphorylation of Munc18-1 inhibits synaptic transmission by preventing SNARE assembly.

artículo científico publicado en 2017

Unfolded protein response activates glycogen synthase kinase-3 via selective lysosomal degradation.

artículo científico publicado en 2013

Vesicle trafficking: pleasure and pain from SM genes.

artículo científico publicado en 2003

Vesicular trafficking of semaphorin 3A is activity-dependent and differs between axons and dendrites.

artículo científico publicado en 2006

Vti Proteins: Beyond Endolysosomal Trafficking

artículo científico publicado en 2018

Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi

artículo científico publicado en 2018

Lista de obras de Ruud F Toonen

A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons

A closer look at FBXO41 as a Parkinson's disease risk factor

Automated analysis of neuronal morphology, synapse number and synaptic recruitment

Automated quantification of cellular traffic in living cells.

CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons

CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons

Ca(2+)-induced recruitment of the secretory vesicle protein DOC2B to the target membrane.

CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles

Correction: Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

Crashpilot Underachieves due to Acetylation at the Nerve Terminal ⬇️

Deletion of Munc18-1 in 5-HT neurons results in rapid degeneration of the 5-HT system and early postnatal lethality.

Dendritic position is a major determinant of presynaptic strength.

Dense-core vesicle biogenesis and exocytosis in neurons lacking chromogranins A and B.

Detection of silent cells, synchronization and modulatory activity in developing cellular networks

Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons.

Dissecting docking and tethering of secretory vesicles at the target membrane.

Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25.

Fbxo41 Promotes Disassembly of Neuronal Primary Cilia

Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences

Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.

Homozygous STXBP1 variant causes encephalopathy and gain-of-function in synaptic transmission

Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticity

Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission

Matrix-dependent local retention of secretory vesicle cargo in cortical neurons

Multi-level characterization of balanced inhibitory-excitatory cortical neuron network derived from human pluripotent stem cells.

Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles

Munc18-1 expression levels control synapse recovery by regulating readily releasable pool size

Munc18-1 in secretion: lonely Munc joins SNARE team and takes control.

Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release

Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission.

Munc18-1 phosphorylation by protein kinase C potentiates vesicle pool replenishment in bovine chromaffin cells.

Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming.

Phosphorylation of synaptotagmin-1 controls a post-priming step in PKC-dependent presynaptic plasticity

Pool size estimations for dense-core vesicles in mammalian CNS neurons

Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1.

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

Regulated exocytosis: merging ideas on fusing membranes.

SALM1 controls synapse development by promoting F-actin/PIP2-dependent Neurexin clustering

SNAP-25 gene family members differentially support secretory vesicle fusion.

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.

Synaptic Effects of Munc18-1 Alternative Splicing in Excitatory Hippocampal Neurons

The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators

The role of Rab3a in secretory vesicle docking requires association/dissociation of guanidine phosphates and Munc18-1.

Tyrosine phosphorylation of Munc18-1 inhibits synaptic transmission by preventing SNARE assembly.

Unfolded protein response activates glycogen synthase kinase-3 via selective lysosomal degradation.

Vesicle trafficking: pleasure and pain from SM genes.

Vesicular trafficking of semaphorin 3A is activity-dependent and differs between axons and dendrites.

Vti Proteins: Beyond Endolysosomal Trafficking

Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi