Lista de obras - Changshun Shao - Dominio Público Uruguay

A human cell-based reporter detects microhomology-mediated end joining

artículo científico publicado en 2011

A missense mutation in SLC33A1, which encodes the acetyl-CoA transporter, causes autosomal-dominant spastic paraplegia (SPG42)

artículo científico publicado en 2008

A novel deletion mutation in GJB1 causes X-linked Charcot-Marie-Tooth disease in a Han Chinese family

artículo científico publicado en 2010

APRT: a versatile in vivo resident reporter of local mutation and loss of heterozygosity

scientific article published on 01 January 1996

Accelerated hepatocellular carcinoma development in CUL4B transgenic mice

artículo científico publicado en 2015

Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea

scientific article published on 26 August 2020

Altered gene expression in kidneys of mice with 2,8-dihydroxyadenine nephrolithiasis

artículo científico publicado en 2000

An osteopontin-integrin interaction plays a critical role in directing adipogenesis and osteogenesis by mesenchymal stem cells

scientific article published on February 2014

Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51.

artículo científico publicado en 2015

Automatic Classification of Label-Free Cells from Small Cell Lung Cancer and Poorly Differentiated Lung Adenocarcinoma with 2D Light Scattering Static Cytometry and Machine Learning

artículo científico publicado en 2018

Autophagy Contributes to the Maintenance of Genomic Integrity by Reducing Oxidative Stress

scientific article published on 25 August 2020

Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes

artículo científico publicado en 2019

Berberine induces oxidative DNA damage and impairs homologous recombination repair in ovarian cancer cells to confer increased sensitivity to PARP inhibition

artículo científico publicado en 2017

Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage.

artículo científico publicado en 2008

Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway.

artículo científico publicado en 2014

Berberine radiosensitizes human esophageal cancer cells by downregulating homologous recombination repair protein RAD51

artículo científico publicado en 2011

Brief report: interferon-gamma induces expansion of Lin(-)Sca-1(+)C-Kit(+) Cells.

artículo científico publicado en 2010

CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFα

artículo científico publicado en 2012

COVID-19 infection: the perspectives on immune responses

artículo científico publicado en 2020

CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis

artículo científico publicado en 2012

CRL4B interacts with and coordinates the SIN3A-HDAC complex to repress CDKN1A and drive cell cycle progression.

artículo científico publicado en 2014

CUL4B activates Wnt/β-catenin signalling in hepatocellular carcinoma by repressing Wnt antagonists.

artículo científico publicado en 2015

CUL4B contributes to cancer stemness by repressing tumor suppressor miR34a in colorectal cancer

scientific article published on 13 February 2020

CUL4B impedes stress-induced cellular senescence by dampening a p53-reactive oxygen species positive feedback loop

artículo científico publicado en 2014

CUL4B negatively regulates Toll-like receptor-triggered proinflammatory responses by repressing Pten transcription

scientific article published on 15 November 2019

CUL4B promotes replication licensing by up-regulating the CDK2-CDC6 cascade.

artículo científico publicado en 2013

Characterization of nuclear localization signal in the N terminus of CUL4B and its essential role in cyclin E degradation and cell cycle progression.

artículo científico publicado en 2009

Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage.

artículo científico publicado en 2013

Chromosome instability contributes to loss of heterozygosity in mice lacking p53

artículo científico publicado en 2000

Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression

artículo científico publicado en 2019

Differentiation of normal and leukemic cells by 2D light scattering label-free static cytometry

artículo científico publicado en 2016

Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress

artículo científico publicado en 2021

Dysregulation of the miR-194-CUL4B negative feedback loop drives tumorigenesis in non-small-cell lung carcinoma.

artículo científico publicado en 2017

Embryonic stem cells and somatic cells differ in mutation frequency and type

artículo científico publicado en 2002

Emerging predictors of the response to the blockade of immune checkpoints in cancer therapy

scientific article published on 12 July 2018

Exome sequencing reveals a heterozygous DLX5 mutation in a Chinese family with autosomal-dominant split-hand/foot malformation.

artículo científico publicado en 2014

Fibrotic liver microenvironment promotes Dll4 and SDF-1-dependent T-cell lineage development

scientific article published on 05 June 2019

GSH-dependent antioxidant defense contributes to the acclimation of colon cancer cells to acidic microenvironment

artículo científico publicado en 2016

HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genes

artículo científico publicado en 2011

HSD11B1 is upregulated synergistically by IFNγ and TNFα and mediates TSG-6 expression in human UC-MSCs

scientific article published on 20 April 2020

Harnessing tumor-associated macrophages as aids for cancer immunotherapy

scientific article published on 05 December 2019

Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks

artículo científico publicado en 2008

Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1.

artículo científico publicado en 2009

IFNγ and TNFα synergistically induce apoptosis of mesenchymal stem/stromal cells via the induction of nitric oxide

scientific article published on 11 January 2019

IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties

artículo científico publicado en 2019

Identification and functional analysis of a SLC33A1: c.339T>G (p.Ser113Arg) variant in the original SPG42 family

artículo científico publicado en 2015

Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases

scientific article published on 01 August 2018

In vivo loss of heterozygosity in T-cells of B6C3F1 Aprt(+/-) mice.

artículo científico publicado en 2000

Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer.

artículo científico publicado en 2018

Inhibition of DYRK1A-EGFR axis by p53-MDM2 cascade mediates the induction of cellular senescence

scientific article published on 25 March 2019

Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells

artículo científico

Irradiation induces cancer lung metastasis through activation of the cGAS-STING-CCL5 pathway in mesenchymal stromal cells

artículo científico publicado en 2020

Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation.

artículo científico publicado en 2015

Label-free light-sheet microfluidic cytometry for the automatic identification of senescent cells.

artículo científico publicado en 2018

Lack of CUL4B in Adipocytes Promotes PPARγ-Mediated Adipose Tissue Expansion and Insulin Sensitivity.

artículo científico publicado en 2016

Lack of CUL4B leads to increased abundance of GFAP-positive cells that is mediated by PTGDS in mouse brain.

artículo científico publicado en 2015

Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development

artículo científico publicado en 2012

Lack of interferon-γ receptor results in a microenvironment favorable for intestinal tumorigenesis

artículo científico publicado en 2016

Lessons learned from the blockade of immune checkpoints in cancer immunotherapy.

artículo científico publicado en 2018

Light-sheet-based 2D light scattering cytometry for label-free characterization of senescent cells.

artículo científico publicado en 2016

Localization of group IIc low molecular weight phospholipase A2 mRNA to meiotic cells in the mouse

artículo científico publicado en 1997

Loss of heterozygosity and point mutation at Aprt locus in T cells and fibroblasts of Pms2-/- mice

artículo científico publicado en 2002

Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3

artículo científico publicado en 2021

MIF produced by bone marrow-derived macrophages contributes to teratoma progression after embryonic stem cell transplantation

artículo científico publicado en 2012

MYC-regulated pseudogene HMGA1P6 promotes ovarian cancer malignancy via augmenting the oncogenic HMGA1/2

artículo científico publicado en 2020

Macrophages inhibit adipogenic differentiation of adipose tissue derived mesenchymal stem/stromal cells by producing pro-inflammatory cytokines

artículo científico publicado en 2020

Mesenchymal stem/stromal cells induce the generation of novel IL-10-dependent regulatory dendritic cells by SOCS3 activation.

artículo científico publicado en 2012

Mesenchymal stromal cells pretreated with pro-inflammatory cytokines promote skin wound healing through VEGFC-mediated angiogenesis

artículo científico publicado en 2020

Metadherin enhances the invasiveness of breast cancer cells by inducing epithelial to mesenchymal transition.

artículo científico publicado en 2011

MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma.

artículo científico publicado en 2012

Mitotic recombination is suppressed by chromosomal divergence in hybrids of distantly related mouse strains

artículo científico publicado en 2001

Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice.

artículo científico publicado en 1999

Mlh1 mediates tissue-specific regulation of mitotic recombination

scientific journal article

Modulation of DNA end joining by nuclear proteins

artículo científico publicado en 2005

Mutagenesis in vivo in T cells of p21-deficient mice

artículo científico publicado en 2009

Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation

artículo científico publicado en 2007

NANOG has a role in mesenchymal stem cells' immunomodulatory effect

artículo científico publicado en 2011

Neferine induces autophagy of human ovarian cancer cells via p38 MAPK/ JNK activation.

artículo científico publicado en 2016

Neferine, an alkaloid ingredient in lotus seed embryo, inhibits proliferation of human osteosarcoma cells by promoting p38 MAPK-mediated p21 stabilization.

artículo científico publicado en 2011

Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction

artículo científico publicado en 2014

Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma

artículo científico publicado en 2018

Pan-senescence transcriptome analysis identified RRAD as a marker and negative regulator of cellular senescence

artículo científico publicado en 2018

Prdx1 deficiency in mice promotes tissue specific loss of heterozygosity mediated by deficiency in DNA repair and increased oxidative stress

artículo científico publicado en 2012

Prenatal diagnosis of autosomal dominant hereditary spastic paraplegia (SPG42) caused by SLC33A1 mutation in a Chinese kindred.

artículo científico publicado en 2010

Radiation-induced genetic instability in vivo depends on p53 status

artículo científico publicado en 2002

Recurrence of the D100N mutation in a Chinese family with brachydactyly type A1: evidence for a mutational hot spot in the Indian hedgehog gene

scientific article published on 01 June 2007

Reduced apoptosis and increased deletion mutations at Aprt locus in vivo in mice exposed to repeated ionizing radiation

artículo científico publicado en 2007

Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks

artículo científico publicado en 2011

Resveratrol augments the canonical Wnt signaling pathway in promoting osteoblastic differentiation of multipotent mesenchymal cells.

artículo científico publicado en 2009

Resveratrol modulates angiogenesis through the GSK3β/β-catenin/TCF-dependent pathway in human endothelial cells

artículo científico publicado en 2010

Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells.

artículo científico publicado en 2017

Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations

artículo científico publicado en 2008

S113R mutation in SLC33A1 leads to neurodegeneration and augmented BMP signaling in a mouse model

artículo científico publicado en 2016

STC2 overexpression mediated by HMGA2 is a biomarker for aggressiveness of high-grade serous ovarian cancer.

artículo científico publicado en 2015

Sequential analysis of kidney stone formation in the Aprt knockout mouse

artículo científico publicado en 2001

Serum withdrawal up-regulates human SIRT1 gene expression in a p53-dependent manner.

artículo científico publicado en 2009

Skeletal muscle stem cells confer maturing macrophages anti-inflammatory properties through insulin-like growth factor-2

artículo científico publicado en 2020

Small scale genetic alterations contribute to increased mutability at the X-linked Hprt locus in vivo in Blm hypomorphic mice

artículo científico publicado en 2010

Somatic recombination redux.

artículo científico publicado en 2003

Specific deletion of TRAF3 in B lymphocytes leads to B-lymphoma development in mice.

artículo científico publicado en 2011

Splicing factor USP39 promotes ovarian cancer malignancy through maintaining efficient splicing of oncogenic HMGA2

artículo científico publicado en 2021

The CUL4B/AKT/β-Catenin Axis Restricts the Accumulation of Myeloid-Derived Suppressor Cells to Prohibit the Establishment of a Tumor-Permissive Microenvironment.

artículo científico publicado en 2015

The critical role of T cells in glucocorticoid-induced osteoporosis

artículo científico publicado en 2020

The tango of ROS and p53 in tissue stem cells.

artículo científico publicado en 2018

Tumor resident mesenchymal stromal cells endow naïve stromal cells with tumor-promoting properties

artículo científico publicado en 2013

Upregulation of IL-6 in CUL4B-deficient myeloid-derived suppressive cells increases the aggressiveness of cancer cells

scientific article published on 24 June 2019

Whole-exome sequencing identifies a variant in TMEM132E causing autosomal-recessive nonsyndromic hearing loss DFNB99.

artículo científico publicado en 2014

X-linked intellectual disability gene CUL4B targets Jab1/CSN5 for degradation and regulates bone morphogenetic protein signaling

artículo científico publicado en 2013

X-rays induce distinct patterns of somatic mutation in fetal versus adult hematopoietic cells

artículo científico publicado en 2007

Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression.

artículo científico publicado en 2014

miR-106a represses the Rb tumor suppressor p130 to regulate cellular proliferation and differentiation in high-grade serous ovarian carcinoma.

artículo científico publicado en 2013

miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma

artículo científico publicado en 2017

miR-17-5p and miR-106a are involved in the balance between osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells

artículo científico publicado en 2012

Lista de obras de Changshun Shao

A human cell-based reporter detects microhomology-mediated end joining

A missense mutation in SLC33A1, which encodes the acetyl-CoA transporter, causes autosomal-dominant spastic paraplegia (SPG42)

A novel deletion mutation in GJB1 causes X-linked Charcot-Marie-Tooth disease in a Han Chinese family

APRT: a versatile in vivo resident reporter of local mutation and loss of heterozygosity

Accelerated hepatocellular carcinoma development in CUL4B transgenic mice

Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea

Altered gene expression in kidneys of mice with 2,8-dihydroxyadenine nephrolithiasis

An osteopontin-integrin interaction plays a critical role in directing adipogenesis and osteogenesis by mesenchymal stem cells

Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51.

Automatic Classification of Label-Free Cells from Small Cell Lung Cancer and Poorly Differentiated Lung Adenocarcinoma with 2D Light Scattering Static Cytometry and Machine Learning

Autophagy Contributes to the Maintenance of Genomic Integrity by Reducing Oxidative Stress

Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes

Berberine induces oxidative DNA damage and impairs homologous recombination repair in ovarian cancer cells to confer increased sensitivity to PARP inhibition

Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage.

Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway.

Berberine radiosensitizes human esophageal cancer cells by downregulating homologous recombination repair protein RAD51

Brief report: interferon-gamma induces expansion of Lin(-)Sca-1(+)C-Kit(+) Cells.

CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFα

COVID-19 infection: the perspectives on immune responses

CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis

CRL4B interacts with and coordinates the SIN3A-HDAC complex to repress CDKN1A and drive cell cycle progression.

CUL4B activates Wnt/β-catenin signalling in hepatocellular carcinoma by repressing Wnt antagonists.

CUL4B contributes to cancer stemness by repressing tumor suppressor miR34a in colorectal cancer

CUL4B impedes stress-induced cellular senescence by dampening a p53-reactive oxygen species positive feedback loop

CUL4B negatively regulates Toll-like receptor-triggered proinflammatory responses by repressing Pten transcription

CUL4B promotes replication licensing by up-regulating the CDK2-CDC6 cascade.

Characterization of nuclear localization signal in the N terminus of CUL4B and its essential role in cyclin E degradation and cell cycle progression.

Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage.

Chromosome instability contributes to loss of heterozygosity in mice lacking p53

Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression

Differentiation of normal and leukemic cells by 2D light scattering label-free static cytometry

Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress

Dysregulation of the miR-194-CUL4B negative feedback loop drives tumorigenesis in non-small-cell lung carcinoma.

Embryonic stem cells and somatic cells differ in mutation frequency and type

Emerging predictors of the response to the blockade of immune checkpoints in cancer therapy

Exome sequencing reveals a heterozygous DLX5 mutation in a Chinese family with autosomal-dominant split-hand/foot malformation.

Fibrotic liver microenvironment promotes Dll4 and SDF-1-dependent T-cell lineage development

GSH-dependent antioxidant defense contributes to the acclimation of colon cancer cells to acidic microenvironment

HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genes

HSD11B1 is upregulated synergistically by IFNγ and TNFα and mediates TSG-6 expression in human UC-MSCs

Harnessing tumor-associated macrophages as aids for cancer immunotherapy

Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks

Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1.

IFNγ and TNFα synergistically induce apoptosis of mesenchymal stem/stromal cells via the induction of nitric oxide

IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties

Identification and functional analysis of a SLC33A1: c.339T>G (p.Ser113Arg) variant in the original SPG42 family

Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases

In vivo loss of heterozygosity in T-cells of B6C3F1 Aprt(+/-) mice.

Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer.

Inhibition of DYRK1A-EGFR axis by p53-MDM2 cascade mediates the induction of cellular senescence

Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells

Irradiation induces cancer lung metastasis through activation of the cGAS-STING-CCL5 pathway in mesenchymal stromal cells

Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation.

Label-free light-sheet microfluidic cytometry for the automatic identification of senescent cells.

Lack of CUL4B in Adipocytes Promotes PPARγ-Mediated Adipose Tissue Expansion and Insulin Sensitivity.

Lack of CUL4B leads to increased abundance of GFAP-positive cells that is mediated by PTGDS in mouse brain.

Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development

Lack of interferon-γ receptor results in a microenvironment favorable for intestinal tumorigenesis

Lessons learned from the blockade of immune checkpoints in cancer immunotherapy.

Light-sheet-based 2D light scattering cytometry for label-free characterization of senescent cells.

Localization of group IIc low molecular weight phospholipase A2 mRNA to meiotic cells in the mouse

Loss of heterozygosity and point mutation at Aprt locus in T cells and fibroblasts of Pms2-/- mice

Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3

MIF produced by bone marrow-derived macrophages contributes to teratoma progression after embryonic stem cell transplantation

MYC-regulated pseudogene HMGA1P6 promotes ovarian cancer malignancy via augmenting the oncogenic HMGA1/2

Macrophages inhibit adipogenic differentiation of adipose tissue derived mesenchymal stem/stromal cells by producing pro-inflammatory cytokines

Mesenchymal stem/stromal cells induce the generation of novel IL-10-dependent regulatory dendritic cells by SOCS3 activation.

Mesenchymal stromal cells pretreated with pro-inflammatory cytokines promote skin wound healing through VEGFC-mediated angiogenesis

Metadherin enhances the invasiveness of breast cancer cells by inducing epithelial to mesenchymal transition.

MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma.

Mitotic recombination is suppressed by chromosomal divergence in hybrids of distantly related mouse strains

Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice.

Mlh1 mediates tissue-specific regulation of mitotic recombination

Modulation of DNA end joining by nuclear proteins

Mutagenesis in vivo in T cells of p21-deficient mice

Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation

NANOG has a role in mesenchymal stem cells' immunomodulatory effect

Neferine induces autophagy of human ovarian cancer cells via p38 MAPK/ JNK activation.

Neferine, an alkaloid ingredient in lotus seed embryo, inhibits proliferation of human osteosarcoma cells by promoting p38 MAPK-mediated p21 stabilization.