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Lista de obras de Moira O'bryan

A de novo paradigm for male infertility

artículo científico publicado en 2022

A framework for high-resolution phenotyping of candidate male infertility mutants: from human to mouse

scientific article published on 04 April 2020

A missense mutation in the transcription factor ETV5 leads to sterility, increased embryonic and perinatal death, postnatal growth restriction, renal asymmetry and polydactyly in the mouse

artículo científico publicado en 2013

A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.

artículo científico publicado en 2017

A novel germ cell protein, SPIF (sperm PKA interacting factor), is essential for the formation of a PKA/TCP11 complex that undergoes conformational and phosphorylation changes upon capacitation

scientific journal article

A novel protein, sperm head and tail associated protein (SHTAP), interacts with cysteine-rich secretory protein 2 (CRISP2) during spermatogenesis in the mouse

artículo científico publicado en 2009

A repository of ENU mutant mouse lines and their potential for male fertility research

artículo científico publicado en 2005

Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo

artículo científico publicado en 2008

Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype

artículo científico publicado en 2009

An essential role for katanin p80 and microtubule severing in male gamete production

artículo científico publicado en 2012

An optimised STAPUT method for the purification of mouse spermatocyte and spermatid populations

artículo científico publicado en 2019

CBE1 Is a Manchette- and Mitochondria-Associated Protein With a Potential Role in Somatic Cell Proliferation

scientific article published on 01 November 2019

CRISP2 Is a Regulator of Multiple Aspects of Sperm Function and Male Fertility

artículo científico publicado en 2019

Cell-specific expression of betaC-activin in the rat reproductive tract, adrenal and liver

artículo científico publicado en 2004

Cellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction

artículo científico publicado en 2008

Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling.

artículo científico publicado en 2018

Changes in circulating and testicular levels of inhibin A and B and activin A during postnatal development in the rat.

artículo científico publicado en 2004

Changes in sperm methylation profile: a potential cause of infertility and a handle to monitor improvements in genetic and lifestyle interactions

artículo científico publicado en 2015

Characterization of gametogenetin 1 (GGN1) and its potential role in male fertility through the interaction with the ion channel regulator, cysteine-rich secretory protein 2 (CRISP2) in the sperm tail

artículo científico publicado en 2008

Claudin-11 and connexin-43 display altered spatial patterns of organization in men with primary seminiferous tubule failure compared with controls

artículo científico publicado en 2013

Clinical Review#: State of the art for genetic testing of infertile men.

artículo científico publicado en 2010

Cloning and regulation of the rat activin betaE subunit

artículo científico publicado en 2000

Constitutive expression of prostaglandin-endoperoxide synthase 2 by somatic and spermatogenic cells is responsible for prostaglandin E2 production in the adult rat testis

artículo científico publicado en 2007

Context-specific behavioural changes induced by exposure to an androgenic endocrine disruptor

scientific article published on 30 January 2019

Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice

scientific journal article

Copy number variation associated with meiotic arrest in idiopathic male infertility

artículo científico publicado en 2014

Cysteine-rich secretory protein 2 binds to mitogen-activated protein kinase kinase kinase 11 in mouse sperm

artículo científico publicado en 2007

Cysteine-rich secretory protein 4 is an inhibitor of transient receptor potential M8 with a role in establishing sperm function

scientific journal article

Cysteine-rich secretory proteins are not exclusively expressed in the male reproductive tract

artículo científico publicado en 2008

Cytokine profiles in the testes of rats treated with lipopolysaccharide reveal localized suppression of inflammatory responses

artículo científico publicado en 2005

DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes.

artículo científico publicado en 2012

DNMT3L is a regulator of X chromosome compaction and post-meiotic gene transcription

artículo científico publicado en 2011

Deficiency of the Tbc1d21 gene causes male infertility with morphological abnormalities of the sperm mitochondria and flagellum in mice

scientific article published on 25 September 2020

Deletion of the Parkin co-regulated gene causes defects in ependymal ciliary motility and hydrocephalus in the quakingviable mutant mouse

artículo científico publicado en 2010

Development of hydrocephalus in mice lacking SOCS7.

scholarly article

Differential effects of dexamethasone treatment on lipopolysaccharide-induced testicular inflammation and reproductive hormone inhibition in adult rats.

artículo científico publicado en 2001

Differential expression of clusterin in inducible models of apoptosis

artículo científico publicado en 1992

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring.

artículo científico publicado en 2016

Endometrial CRISP3 is regulated throughout the mouse estrous and human menstrual cycle and facilitates adhesion and proliferation of endometrial epithelial cells

artículo científico publicado en 2015

Epididymal cysteine-rich secretory proteins are required for epididymal sperm maturation and optimal sperm function

artículo científico publicado en 2018

Epigenetic regulation in male germ cells

artículo científico publicado en 2008

Eukaryotic expression, purification and structure/function analysis of native, recombinant CRISP3 from human and mouse

artículo científico publicado en 2014

Exome sequencing reveals novel causes as well as new candidate genes for human globozoospermia

scientific article published on 01 January 2020

Exome sequencing reveals variants in known and novel candidate genes for severe sperm motility disorders

artículo científico publicado en 2021

Expression and Localization of Activin Subunits and Follistatins in Tissues from Men with High Grade Prostate Cancer ⬇️

artículo científico publicado el 1 de noviembre de 1997

Expression and purification of recombinant mouse CRISP4 using a baculovirus system

scientific article published on 20 November 2019

Expression of ciliated bronchial epithelium 1 during human spermatogenesis

artículo científico publicado en 2017

Expression of katanin p80 in human spermatogenesis

artículo científico publicado en 2016

Expression of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor in normal and inflamed rat testis

artículo científico publicado en 2002

Expression patterns of HENMT1 and PIWIL1 in human testis: implications for transposon expression.

artículo científico publicado en 2017

FGFR-1 [corrected] signaling is involved in spermiogenesis and sperm capacitation

artículo científico publicado en 2005

Fat aussie--a new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis

scientific journal article

GGN1 in the testis and ovary and its variance within the Australian fertile and infertile male population.

artículo científico publicado en 2010

GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse

scientific article published on 31 October 2019

GSK3 inhibition, but not epigenetic remodeling, mediates efficient derivation of germline embryonic stem cells from nonobese diabetic mice

artículo científico publicado en 2018

Generation of stable pluripotent stem cells from NOD mouse tail-tip fibroblasts

artículo científico publicado en 2011

Genetic screening of infertile men.

artículo científico publicado en 2004

Genetic variants in the ETV5 gene in fertile and infertile men with nonobstructive azoospermia associated with Sertoli cell-only syndrome.

artículo científico publicado en 2012

Genetic variants in the RABL2A gene in fertile and oligoasthenospermic infertile men.

artículo científico publicado en 2014

Genetic variants in the human glucocorticoid-induced leucine zipper (GILZ) gene in fertile and infertile men.

artículo científico publicado en 2013

Genome-wide ENU mutagenesis for the discovery of novel male fertility regulators

artículo científico publicado en 2010

Germ cell arrest associated with aSETX mutation in ataxia oculomotor apraxia type 2

scientific article published on 09 January 2019

Glioma pathogenesis-related 1-like 1 is testis enriched, dynamically modified, and redistributed during male germ cell maturation and has a potential role in sperm-oocyte binding

scientific journal article

Glucocorticoid-induced leucine zipper (GILZ) regulates testicular FOXO1 activity and spermatogonial stem cell (SSC) function

artículo científico publicado en 2013

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.

artículo científico publicado en 2015

Haploid male germ cells-the Grand Central Station of protein transport

scientific article published on 21 April 2020

Health and fertility of ICSI-conceived young men: study protocol

scientific article published on 03 October 2020

Human sperm NADH and NADPH diaphorase cytochemistry: correlation with sperm motility.

artículo científico publicado en 1998

Human sperm associated antigen 4 (SPAG4) is a potential cancer marker

artículo científico publicado en 2003

Human sperm endothelial nitric oxide synthase expression: correlation with sperm motility

artículo científico publicado en 1998

Identification of a novel apolipoprotein, ApoN, in ovarian follicular fluid

scientific journal article

Identification of a novel testis-specific member of the phosphatidylethanolamine binding protein family, pebp-2

scientific journal article

Identification of a rat testis-specific gene encoding a potential rat outer dense fibre protein ⬇️

artículo científico publicado el 1 de julio de 1998

Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse

artículo científico publicado en 2008

Immunohistochemical Localization of Endothelial Nitric Oxide Synthase in Human Testis, Epididymis, and Vas Deferens Suggests a Possible Role for Nitric Oxide in Spermatogenesis, Sperm Maturation, and Programmed Cell Death1

artículo científico publicado en 1996

Impact of the widespread pharmaceutical pollutant fluoxetine on behaviour and sperm traits in a freshwater fish

artículo científico publicado en 2018

In vivo evidence that RBM5 is a tumour suppressor in the lung

artículo científico publicado en 2017

Inflammatory networks in the control of spermatogenesis : chronic inflammation in an immunologically privileged tissue?

artículo científico publicado en 2008

Interviews with andrologists (part 2). Interview by Katja Wolski

artículo científico publicado en 2006

Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human sperm-oocyte recognition.

artículo científico publicado en 2012

Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae

artículo científico publicado en 2011

KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility

artículo científico publicado en 2012

KATNB1 in the human testis and its genetic variants in fertile and oligoasthenoteratozoospermic infertile men.

artículo científico publicado en 2014

Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse.

artículo científico publicado en 2017

LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility

scientific journal article

LRGUK1 is part of a multiprotein complex required for manchette function and male fertility

artículo científico publicado en 2016

Long-term follow-up of ICSI-conceived offspring compared with spontaneously conceived offspring: a systematic review of health outcomes beyond the neonatal period

article

Long-term follow-up of intra-cytoplasmic sperm injection-conceived offspring compared with in vitro fertilization-conceived offspring: a systematic review of health outcomes beyond the neonatal period.

artículo científico publicado en 2017

Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse

scientific journal article

Loss of the nuclear receptor corepressor SLIRP compromises male fertility

artículo científico publicado en 2013

Meeting Review: Joint Prince Henry's Institute of Medical Research and Monash Institute of Reproduction and Development Symposium - Reproductive Genomics

artículo científico publicado en 2002

Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis.

artículo científico publicado en 2005

Microtubules and spermatogenesis

artículo científico publicado en 2014

Modifiers of epigenetic reprogramming show paternal effects in the mouse.

artículo científico publicado en 2007

Molecular analysis of the PArkin co-regulated gene and association with male infertility

artículo científico publicado en 2009

Motility induced changes in viscosity of suspensions of swimming microbes in extensional flows

artículo científico publicado en 2015

Mouse models as tools in fertility research and male-based contraceptive development.

artículo científico publicado en 2010

Mouse models for genes involved in impaired spermatogenesis.

artículo científico publicado en 2006

Mouse models in male fertility research

artículo científico publicado en 2010

Mutations in the Katnb1 gene cause left-right asymmetry and heart defects

artículo científico publicado en 2017

N-ethyl-N-nitrosourea (ENU) mutagenesis and male fertility research.

artículo científico publicado en 2006

Need for standardization and confirmation of STS deletions on the Y chromosome

artículo científico publicado en 2008

Nitric oxide synthase activity in human seminal plasma

artículo científico publicado en 2001

Normal live birth after testicular sperm extraction and intracytoplasmic sperm injection in variant primary ciliary dyskinesia with completely immotile sperm and structurally abnormal sperm tails

artículo científico publicado en 2011

PLAG1 deficiency impairs spermatogenesis and sperm motility in mice.

artículo científico publicado en 2017

PURIFICATION AND CELLULAR LOCALIZATION OF β2-MICROGLOBULIN IN THE TESTIS

scientific article published on 01 January 1997

Phenotypic variation within European carriers of the Y-chromosomal gr/gr deletion is independent of Y-chromosomal background.

artículo científico publicado en 2008

Phenotyping male infertility in the mouse: how to get the most out of a 'non-performer'

artículo científico publicado en 2009

Polymorphisms in the human cysteine-rich secretory protein 2 (CRISP2) gene in Australian men.

artículo científico publicado en 2008

Proteomic and functional analysis of human sperm detergent resistant membranes.

artículo científico publicado en 2011

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

artículo científico publicado en 2012

RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State

artículo científico publicado en 2016

RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility

artículo científico publicado en 2013

Rare mutations in the complement regulatory gene CSMD1 are associated with male and female infertility

scientific article published on 11 October 2019

Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

scientific article published on 20 September 2018

Regulation of Germ Cell and Sertoli Cell Development by Activin, Follistatin, and FSH

article

SOX30 is required for male fertility in mice

artículo científico publicado en 2017

SP-40,40 is an inhibitor of C5b-6-initiated haemolysis

artículo científico publicado en 1989

Sox8 and Sertoli-cell Function

article

Sox8 is a critical regulator of adult Sertoli cell function and male fertility

scientific journal article

Spermiation: The process of sperm release

artículo científico publicado en 2011

TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction

scientific article published on 01 June 2011

The CAP superfamily: cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins--roles in reproduction, cancer, and immune defense

artículo científico publicado en 2008

The Y chromosome gr/gr subdeletion is associated with male infertility

article

The antidepressant fluoxetine alters mechanisms of pre- and post-copulatory sexual selection in the eastern mosquitofish (Gambusia holbrooki).

artículo científico publicado en 2018

The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling

artículo científico publicado en 2005

The cytoskeleton in spermatogenesis

scientific article published on 01 February 2019

The functions of CAP superfamily proteins in mammalian fertility and disease

artículo científico publicado en 2020

The generation of live offspring from vitrified oocytes

artículo científico publicado en 2011

The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors.

artículo científico publicado en 2005

The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis

scientific journal article

The response of testicular leukocytes to lipopolysaccharide-induced inflammation: further evidence for heterogeneity of the testicular macrophage population

artículo científico publicado en 2002

The role of cysteine-rich secretory proteins in male fertility

artículo científico publicado en 2010

The testis and epididymis are productively infected by SIV and SHIV in juvenile macaques during the post-acute stage of infection

artículo científico publicado en 2007

The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice

scientific journal article

Tpx-1 is a component of the outer dense fibers and acrosome of rat spermatozoa

artículo científico publicado en 2001

Uncoupling of transcription and translation of Fanconi anemia (FANC) complex proteins during spermatogenesis

artículo científico publicado en 2014

Utilising the resources of the International Knockout Mouse Consortium: the Australian experience

artículo científico

Validation and application of a novel integrated genetic screening method to a cohort of 1,112 men with idiopathic azoospermia or severe oligozoospermia

artículo científico publicado en 2017

Vinclozolin exposure in utero induces postpubertal prostatitis and reduces sperm production via a reversible hormone-regulated mechanism

scientific journal article

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