Lista de obras - Aengus Mac Sweeney - Dominio Público Uruguay

Crystal structure of delta-chymotrypsin bound to a peptidyl chloromethyl ketone inhibitor

artículo científico publicado en 2000

Crystallization and preliminary crystallographic analysis of an NADH oxidase that functions in peroxide reduction in Thermus aquaticus YT-1.

artículo científico publicado en 1999

Discovery and structure-based optimization of adenain inhibitors.

artículo científico publicado en 2014

Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases

scientific article published on 19 February 2020

Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria

artículo científico publicado en 2019

High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrolidine

artículo científico publicado en 2003

Insights into the regulatory mechanism for caspase-8 activation

scientific journal article

Modified microbatch and seeding in protein crystallization experiments.

artículo científico publicado en 2003

Practical aspects of using the microbatch method in screening conditions for protein crystallization

artículo científico publicado en 2004

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

artículo científico publicado en 2019

Small-molecule factor D inhibitors targeting the alternative complement pathway

artículo científico publicado en 2016

Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases

artículo científico publicado en 2008

Structure-based design and optimization of potent inhibitors of the adenoviral protease

artículo científico publicado en 2015

The 1.15A crystal structure of the Staphylococcus aureus methionyl-aminopeptidase and complexes with triazole based inhibitors

artículo científico publicado en 2003

The advantages of using a modified microbatch method for rapid screening of protein crystallization conditions

artículo científico publicado en 2003

The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation

artículo científico publicado en 2005

The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms.

artículo científico publicado en 2018

Using natural seeding material to generate nucleation in protein crystallization experiments

artículo científico publicado en 2003

Lista de obras de Aengus Mac Sweeney

Crystal structure of delta-chymotrypsin bound to a peptidyl chloromethyl ketone inhibitor

Crystallization and preliminary crystallographic analysis of an NADH oxidase that functions in peroxide reduction in Thermus aquaticus YT-1.

Discovery and structure-based optimization of adenain inhibitors.

Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases

Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria

High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrolidine

Insights into the regulatory mechanism for caspase-8 activation

Modified microbatch and seeding in protein crystallization experiments.

Practical aspects of using the microbatch method in screening conditions for protein crystallization

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Small-molecule factor D inhibitors targeting the alternative complement pathway

Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases

Structure-based design and optimization of potent inhibitors of the adenoviral protease

The 1.15A crystal structure of the Staphylococcus aureus methionyl-aminopeptidase and complexes with triazole based inhibitors

The advantages of using a modified microbatch method for rapid screening of protein crystallization conditions

The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation

The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms.

Using natural seeding material to generate nucleation in protein crystallization experiments