Lista de obras - Stephane Angers - Dominio Público Uruguay

A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy

artículo científico publicado en 2021

A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion

artículo científico publicado en 2015

A bacterial acetyltransferase destroys plant microtubule networks and blocks secretion

artículo científico publicado en 2012

A novel assay for measurement of membrane-protein surface expression using a β-lactamase

artículo científico publicado en 2013

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.

artículo científico publicado en 2011

A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells

artículo científico publicado en 2018

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells

artículo científico publicado en 2017

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

artículo científico publicado en 2017

An aplysia dopamine1-like receptor: molecular and functional characterization

artículo científico publicado en 2005

Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.

artículo científico publicado en 1999

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

artículo científico publicado en 2003

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates

artículo científico publicado en 2015

Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells

artículo científico publicado en 2001

Ca(2+)/calmodulin-dependent protein kinase II interacts with group I metabotropic glutamate and facilitates receptor endocytosis and ERK1/2 signaling: role of β-amyloid

artículo científico publicado en 2015

Calcium-sensing receptor modulates cell adhesion and migration via integrins

scientific journal article

Constitutive Agonist-independent CCR5 Oligomerization and Antibody-mediated Clustering Occurring at Physiological Levels of Receptors

artículo científico publicado en 2002

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

scientific article published on 24 July 2020

Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)

artículo científico publicado en 2000

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

artículo científico publicado en 2002

Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins

artículo científico publicado en 2016

Emerging non-canonical functions for heterotrimeric G proteins in cellular signaling

artículo científico

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay

artículo científico publicado en 2016

Evasion of p53 and G2/M checkpoints are characteristic of Hh-driven basal cell carcinoma.

artículo científico publicado en 2013

Functional characterization of a novel serotonin receptor (5-HTap2) expressed in the CNS of Aplysia californica

artículo científico publicado en 2002

Functional significance of oligomerization of G-protein-coupled receptors.

artículo científico publicado en 2000

G protein betagamma subunits regulate cell adhesion through Rap1a and its effector Radil

artículo científico publicado en 2010

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

artículo científico publicado en 2016

Gli proteins in development and disease

artículo científico

Glutamate transporter coupling to Na,K-ATPase.

artículo científico publicado en 2009

Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling.

artículo científico publicado en 2015

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.

artículo científico publicado en 2018

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

artículo científico publicado en 2015

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

scientific article published on 23 September 2019

Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting

artículo científico publicado en 2004

IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers

artículo científico publicado en 2020

Identification of Novel Smoothened Ligands Using Structure-Based Docking

artículo científico publicado en 2016

Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells

artículo científico publicado en 2012

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression

artículo científico publicado en 2012

Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation

artículo científico publicado en 2011

Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1.

artículo científico publicado en 2009

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

artículo científico publicado en 2006

Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer

artículo científico publicado en 2002

New insights in the regulation of Rab GTPases by G protein-coupled receptors

artículo científico publicado en 2014

New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening

artículo científico publicado en 2008

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability

artículo científico publicado en 2013

Oligomeric size of the m2 muscarinic receptor in live cells as determined by quantitative fluorescence resonance energy transfer

artículo científico publicado en 2010

PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2.

artículo científico publicado en 2016

Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants

scientific journal article

Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells

artículo científico publicado en 2014

Proteomic analyses of protein complexes in the Wnt pathway

artículo científico publicado en 2008

Proximal events in Wnt signal transduction

artículo científico publicado en 2009

Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development

artículo científico publicado en 2014

Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development.

artículo científico publicado en 2013

Publisher Correction: A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells

artículo científico publicado en 2018

Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer

artículo científico publicado en 2002

Radil controls neutrophil adhesion and motility through β2-integrin activation

artículo científico publicado en 2012

Recovery of oligomers and cooperativity when monomers of the M2 muscarinic cholinergic receptor are reconstituted into phospholipid vesicles

artículo científico publicado en 2007

Reply: beyond receptor dimerization

artículo científico publicado en 2000

Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity

artículo científico publicado en 2016

SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex

artículo científico publicado en 2016

Scalable, FACS-Free Genome-Wide Phenotypic Screening

Separating the Anti-Inflammatory and Diabetogenic Effects of Glucocorticoids Through LXRβ Antagonism.

artículo científico publicado en 2017

Single molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival

scientific article published in 2021

Stepping stone: a cytohesin adaptor for membrane cytoskeleton restraint in the syncytial Drosophila embryo

artículo científico publicado en 2014

Systematic discovery and classification of human cell line essential genes

article

Systematic protein-protein interaction mapping for clinically relevant human GPCRs

artículo científico publicado en 2017

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

artículo científico publicado en 2019

Tandem affinity purification and identification of heterotrimeric g protein-associated proteins

artículo científico publicado en 2011

Tandem affinity purification to identify cytosolic and nuclear gβγ-interacting proteins

artículo científico publicado en 2015

The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS).

artículo científico publicado en 2002

The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity

artículo científico publicado en 2015

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

artículo científico publicado en 2006

The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling

artículo científico publicado en 2014

The Pseudomonas syringae type III effector HopF2 suppresses Arabidopsis stomatal immunity

artículo científico publicado en 2014

The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions

artículo científico publicado en 2013

The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling

artículo científico publicado en 2011

Ubiquitylation and activation of a Rab GTPase is promoted by a β₂AR-HACE1 complex.

artículo científico publicado en 2013

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.

artículo científico publicado en 2016

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

artículo científico publicado en 2007

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells

artículo científico publicado en 2019

Wnt signaling in development and tissue homeostasis

article

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

scientific journal article

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.

artículo científico publicado en 2016

Lista de obras de Stephane Angers

A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy

A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion

A bacterial acetyltransferase destroys plant microtubule networks and blocks secretion

A novel assay for measurement of membrane-protein surface expression using a β-lactamase

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.

A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

An aplysia dopamine1-like receptor: molecular and functional characterization

Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates

Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells

Ca(2+)/calmodulin-dependent protein kinase II interacts with group I metabotropic glutamate and facilitates receptor endocytosis and ERK1/2 signaling: role of β-amyloid

Calcium-sensing receptor modulates cell adhesion and migration via integrins

Constitutive Agonist-independent CCR5 Oligomerization and Antibody-mediated Clustering Occurring at Physiological Levels of Receptors

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins

Emerging non-canonical functions for heterotrimeric G proteins in cellular signaling

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay

Evasion of p53 and G2/M checkpoints are characteristic of Hh-driven basal cell carcinoma.

Functional characterization of a novel serotonin receptor (5-HTap2) expressed in the CNS of Aplysia californica

Functional significance of oligomerization of G-protein-coupled receptors.

G protein betagamma subunits regulate cell adhesion through Rap1a and its effector Radil

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

Gli proteins in development and disease

Glutamate transporter coupling to Na,K-ATPase.

Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling.

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting

IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers

Identification of Novel Smoothened Ligands Using Structure-Based Docking

Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression

Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation

Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1.

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer

New insights in the regulation of Rab GTPases by G protein-coupled receptors

New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability

Oligomeric size of the m2 muscarinic receptor in live cells as determined by quantitative fluorescence resonance energy transfer

PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2.

Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants

Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells

Proteomic analyses of protein complexes in the Wnt pathway

Proximal events in Wnt signal transduction

Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development

Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development.

Publisher Correction: A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells

Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer

Radil controls neutrophil adhesion and motility through β2-integrin activation

Recovery of oligomers and cooperativity when monomers of the M2 muscarinic cholinergic receptor are reconstituted into phospholipid vesicles

Reply: beyond receptor dimerization

Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity

SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex

Scalable, FACS-Free Genome-Wide Phenotypic Screening

Separating the Anti-Inflammatory and Diabetogenic Effects of Glucocorticoids Through LXRβ Antagonism.

Single molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival

Stepping stone: a cytohesin adaptor for membrane cytoskeleton restraint in the syncytial Drosophila embryo

Systematic discovery and classification of human cell line essential genes

Systematic protein-protein interaction mapping for clinically relevant human GPCRs

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

Tandem affinity purification and identification of heterotrimeric g protein-associated proteins

Tandem affinity purification to identify cytosolic and nuclear gβγ-interacting proteins

The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS).

The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling

The Pseudomonas syringae type III effector HopF2 suppresses Arabidopsis stomatal immunity

The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions

The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling

Ubiquitylation and activation of a Rab GTPase is promoted by a β₂AR-HACE1 complex.

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.