Lista de obras - Lindsay Tulloch - Dominio Público Uruguay

A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

scientific journal article

Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.

artículo científico publicado en 2018

Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis

artículo científico publicado en 2008

Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors

artículo científico publicado en 2016

Direct and indirect approaches to identify drug modes of action.

artículo científico publicado en 2017

Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development

artículo científico publicado en 2008

Diversity oriented syntheses of fused pyrimidines designed as potential antifolates

artículo científico publicado en 2009

Greasing the wheels or a spanner in the works? Regulation of the cardiac sodium pump by palmitoylation.

artículo científico publicado en 2018

High-resolution structures ofTrypanosoma bruceipteridine reductase ligand complexes inform on the placement of new molecular entities in the active site of a potential drug target

artículo científico publicado en 2010

Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.

artículo científico publicado en 2014

One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening

artículo científico publicado en 2009

Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues.

artículo científico publicado en 2017

Regulation of the cardiac Na(+) pump by palmitoylation of its catalytic and regulatory subunits.

artículo científico

Regulation of the cardiac sodium pump

artículo científico publicado en 2013

Robust neutralising activity and activation of neutrophil cytotoxic responses mediated by antibodies targeting the HTLV-1 envelope glycoprotein

artículo científico publicado en 2011

Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins

artículo científico publicado en 2017

Structure and reactivity of Trypanosoma brucei pteridine reductase: inhibition by the archetypal antifolate methotrexate

artículo científico publicado en 2006

Structure of recombinantLeishmania donovanipteridine reductase reveals a disordered active site ⬇️

artículo científico publicado en 2011

Structure ofStaphylococcus aureus1,4-dihydroxy-2-naphthoyl-CoA synthase (MenB) in complex with acetoacetyl-CoA

artículo científico publicado en 2007

Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases

artículo científico publicado en 2010

Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase

artículo científico publicado en 2019

Sulphate removal induces a major conformational change in Leishmania mexicana pyruvate kinase in the crystalline state

artículo científico publicado en 2008

The inhibitory effect of phospholemman on the sodium pump requires its palmitoylation.

artículo científico publicado en 2011

The trypanosome alternative oxidase: a potential drug target?

artículo científico publicado en 2016

Lista de obras de Lindsay Tulloch

A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.

Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis

Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors

Direct and indirect approaches to identify drug modes of action.

Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development

Diversity oriented syntheses of fused pyrimidines designed as potential antifolates

Greasing the wheels or a spanner in the works? Regulation of the cardiac sodium pump by palmitoylation.

High-resolution structures ofTrypanosoma bruceipteridine reductase ligand complexes inform on the placement of new molecular entities in the active site of a potential drug target

Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.

One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening

Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues.

Regulation of the cardiac Na(+) pump by palmitoylation of its catalytic and regulatory subunits.

Regulation of the cardiac sodium pump

Robust neutralising activity and activation of neutrophil cytotoxic responses mediated by antibodies targeting the HTLV-1 envelope glycoprotein

Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins

Structure and reactivity of Trypanosoma brucei pteridine reductase: inhibition by the archetypal antifolate methotrexate

Structure of recombinantLeishmania donovanipteridine reductase reveals a disordered active site ⬇️

Structure ofStaphylococcus aureus1,4-dihydroxy-2-naphthoyl-CoA synthase (MenB) in complex with acetoacetyl-CoA

Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases

Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase

Sulphate removal induces a major conformational change in Leishmania mexicana pyruvate kinase in the crystalline state

The inhibitory effect of phospholemman on the sodium pump requires its palmitoylation.

The trypanosome alternative oxidase: a potential drug target?