Lista de obras - Lucas Bleicher - Dominio Público Uruguay

A new method bridging graph theory and residue co-evolutionary networks for specificity determinant positions detection

artículo científico publicado en 2019

CONAN: A web application to detect specificity determinants and functional sites by amino acids co-variation network analysis

scientific article published on 11 August 2020

Characterization of an Allosteric Pocket in Zika Virus NS2B-NS3 Protease

artículo científico publicado en 2022

Closed- and open-state models of human skeletal muscle sodium channel

artículo científico publicado en 2018

Coevolved Positions Represent Key Functional Properties in the Trypsin-Like Serine Proteases Protein Family

scientific article published on 16 January 2020

Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding

artículo científico publicado en 2010

Conservation analysis and decomposition of residue correlation networks in the phospholipase A2 superfamily (PLA2s): Insights into the structure-function relationships of snake venom toxins

artículo científico publicado en 2018

Coq7p relevant residues for protein activity and stability

artículo científico publicado en 2015

Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia)

artículo científico publicado en 2010

Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22

artículo científico publicado en 2009

Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism

artículo científico publicado en 2008

Crystal structure of yeast hexokinase PI in complex with glucose: A classical "induced fit" example revised

artículo científico publicado en 2008

Crystallization and preliminary crystallographic analysis of laminarinase from Rhodothermus marinus: a case of pseudomerohedral twinning.

artículo científico publicado en 2008

Crystallization and preliminary structural analysis of the giant haemoglobin fromGlossoscolex paulistusat 3.2 Å ⬇️

artículo científico publicado el 5 de noviembre de 2010

Glutantβase: a database for improving the rational design of glucose-tolerant β-glucosidases

artículo científico publicado en 2020

Her2p molecular modeling, mutant analysis and intramitochondrial localization.

artículo científico publicado en 2013

Identification of new bacteria harboring qnrS and aac(6')-Ib/cr and mutations possibly involved in fluoroquinolone resistance in raw sewage and activated sludge samples from a full-scale WWTP.

artículo científico publicado en 2016

Low-resolution structure and fluorescence anisotropy analysis of protein tyrosine phosphatase eta catalytic domain

artículo científico publicado en 2007

Mitochondrial ribosome bL34 mutants present diminished translation of cytochrome c oxidase subunits

artículo científico publicado en 2017

Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from Rhodothermus marinus and molecular dynamics simulations

artículo científico publicado en 2011

Novel Zn2+-binding Sites in Human Transthyretin: IMPLICATIONS FOR AMYLOIDOGENESIS AND RETINOL-BINDING PROTEIN RECOGNITION

artículo científico publicado en 2010

Novel arsenic-transforming bacteria and the diversity of their arsenic-related genes and enzymes arising from arsenic-polluted freshwater sediment

artículo científico publicado en 2017

Orphan nuclear receptor NGFI-B forms dimers with nonclassical interface.

artículo científico publicado en 2007

PFstats: A Network-Based Open Tool for Protein Family Analysis

scientific article published on 26 February 2018

Residue correlation networks in nuclear receptors reflect functional specialization and the formation of the nematode-specific P-box

artículo científico publicado en 2013

Sequence, structure and function relationships in flaviviruses as assessed by evolutive aspects of its conserved non-structural protein domains

artículo científico publicado en 2017

Site-directed mutagenesis and structural modeling of Coq10p indicate the presence of a tunnel for coenzyme Q6 binding

artículo científico publicado en 2010

Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae

artículo científico publicado en 2017

Structural and immunological characterization of a new nucleotidyltransferase-like antigen from Paracoccidioides brasiliensis

artículo científico publicado en 2019

Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms

artículo científico publicado en 2008

Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function

scientific article published on 19 May 2006

Systematic structural studies of iron superoxide dismutases from human parasites and a statistical coupling analysis of metal binding specificity

artículo científico publicado en 2009

Thyroxine-binding globulin deficiency due to a novel SERPINA7 mutation: Clinical characterization, analysis of X-chromosome inactivation pattern and protein structural modeling

scientific article published on 04 May 2018

Using amino acid correlation and community detection algorithms to identify functional determinants in protein families

artículo científico publicado en 2011

Lista de obras de Lucas Bleicher

A new method bridging graph theory and residue co-evolutionary networks for specificity determinant positions detection

CONAN: A web application to detect specificity determinants and functional sites by amino acids co-variation network analysis

Characterization of an Allosteric Pocket in Zika Virus NS2B-NS3 Protease

Closed- and open-state models of human skeletal muscle sodium channel

Coevolved Positions Represent Key Functional Properties in the Trypsin-Like Serine Proteases Protein Family

Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding

Conservation analysis and decomposition of residue correlation networks in the phospholipase A2 superfamily (PLA2s): Insights into the structure-function relationships of snake venom toxins

Coq7p relevant residues for protein activity and stability

Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia)

Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22

Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism

Crystal structure of yeast hexokinase PI in complex with glucose: A classical "induced fit" example revised

Crystallization and preliminary crystallographic analysis of laminarinase from Rhodothermus marinus: a case of pseudomerohedral twinning.

Crystallization and preliminary structural analysis of the giant haemoglobin fromGlossoscolex paulistusat 3.2 Å ⬇️

Glutantβase: a database for improving the rational design of glucose-tolerant β-glucosidases

Her2p molecular modeling, mutant analysis and intramitochondrial localization.

Identification of new bacteria harboring qnrS and aac(6')-Ib/cr and mutations possibly involved in fluoroquinolone resistance in raw sewage and activated sludge samples from a full-scale WWTP.

Low-resolution structure and fluorescence anisotropy analysis of protein tyrosine phosphatase eta catalytic domain

Mitochondrial ribosome bL34 mutants present diminished translation of cytochrome c oxidase subunits

Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from Rhodothermus marinus and molecular dynamics simulations

Novel Zn2+-binding Sites in Human Transthyretin: IMPLICATIONS FOR AMYLOIDOGENESIS AND RETINOL-BINDING PROTEIN RECOGNITION

Novel arsenic-transforming bacteria and the diversity of their arsenic-related genes and enzymes arising from arsenic-polluted freshwater sediment

Orphan nuclear receptor NGFI-B forms dimers with nonclassical interface.

PFstats: A Network-Based Open Tool for Protein Family Analysis

Residue correlation networks in nuclear receptors reflect functional specialization and the formation of the nematode-specific P-box

Sequence, structure and function relationships in flaviviruses as assessed by evolutive aspects of its conserved non-structural protein domains

Site-directed mutagenesis and structural modeling of Coq10p indicate the presence of a tunnel for coenzyme Q6 binding

Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae

Structural and immunological characterization of a new nucleotidyltransferase-like antigen from Paracoccidioides brasiliensis

Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms

Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function

Systematic structural studies of iron superoxide dismutases from human parasites and a statistical coupling analysis of metal binding specificity

Thyroxine-binding globulin deficiency due to a novel SERPINA7 mutation: Clinical characterization, analysis of X-chromosome inactivation pattern and protein structural modeling

Using amino acid correlation and community detection algorithms to identify functional determinants in protein families