Lista de obras - John Fazakerley - Dominio Público Uruguay

A new index of agonal state for neurological disease

artículo científico publicado en 2011

A single amino acid change in the nuclear localization sequence of the nsP2 protein affects the neurovirulence of Semliki Forest virus

artículo científico publicado en 2002

A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication

artículo científico publicado en 2013

Ability of the Encephalitic Arbovirus Semliki Forest Virus To Cross the Blood-Brain Barrier Is Determined by the Charge of the E2 Glycoprotein

artículo científico publicado en 2015

Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs.

artículo científico publicado en 2003

Advances in dissecting mosquito innate immune responses to arbovirus infection

artículo científico publicado en 2009

Antiviral RNA interference responses induced by Semliki Forest virus infection of mosquito cells: characterization, origin, and frequency-dependent functions of virus-derived small interfering RNAs

artículo científico publicado en 2010

Antiviral responses of arthropod vectors: an update on recent advances

artículo científico publicado en 2014

Attenuation of bunyavirus replication by rearrangement of viral coding and noncoding sequences

artículo científico publicado en 2005

Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon.

artículo científico publicado en 2002

CNS gene therapy applications of the Semliki Forest virus 1 vector are limited by neurotoxicity

artículo científico publicado en 2006

Cell-to-Cell Spread of the RNA Interference Response Suppresses Semliki Forest Virus (SFV) Infection of Mosquito Cell Cultures and Cannot Be Antagonized by SFV

artículo científico publicado en 2009

Characterization of the cellular and cytokine response in the central nervous system following Semliki Forest virus infection

artículo científico publicado en 1997

Coinfection of tick cell lines has variable effects on replication of intracellular bacterial and viral pathogens

artículo científico publicado en 2014

Computer analysis suggests a role for signal sequences in processing polyproteins of enveloped RNA viruses and as a mechanism of viral fusion

artículo científico publicado en 1989

Cyclosporin, blood-brain barrier, and multiple sclerosis

artículo científico publicado en 1985

Cyclosporine enhances virally induced T-cell-mediated demyelination. The effect of cyclosporine on a demyelinating virus infection

artículo científico publicado en 1987

Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines

artículo científico publicado en 2012

Differences in Processing Determinants of Nonstructural Polyprotein and in the Sequence of Nonstructural Protein 3 Affect Neurovirulence of Semliki Forest Virus

artículo científico publicado en 2015

Differential expression of erythroid genes in prion disease.

artículo científico publicado en 2007

Following Acute Encephalitis, Semliki Forest Virus is Undetectable in the Brain by Infectivity Assays but Functional Virus RNA Capable of Generating Infectious Virus Persists for Life ⬇️

artículo científico publicado en 2018

Gene expression analysis in distinct regions of the central nervous system during the development of SSBP/1 sheep scrapie

artículo científico publicado en 2010

Gene expression profiling of the preclinical scrapie-infected hippocampus

artículo científico publicado en 2005

Gene silencing in tick cell lines using small interfering or long double-stranded RNA.

artículo científico publicado en 2012

Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection ⬇️

artículo científico publicado en 2016

Identification of up-regulated genes by array analysis in scrapie-infected mouse brains.

artículo científico publicado en 2004

In Semliki Forest virus encephalitis, antibody rapidly clears infectious virus and is required to eliminate viral material from the brain, but is not required to generate lesions of demyelination

artículo científico publicado en 2008

In memoriam--Richard M. Elliott (1954-2015)

artículo científico publicado en 2015

In response to pathogens, glial cells dynamically and differentially regulate Toll-like receptor gene expression

artículo científico publicado en 2005

Inducible cytokine gene expression in the brain in the ME7/CV mouse model of scrapie is highly restricted, is at a strikingly low level relative to the degree of gliosis and occurs only late in disease

artículo científico publicado en 2003

Induction and suppression of tick cell antiviral RNAi responses by tick-borne flaviviruses

artículo científico publicado en 2014

Innate immune response gene expression profiles of N9 microglia are pathogen-type specific

artículo científico publicado en 2006

Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus

artículo científico publicado en 2007

Investigation of frequency of active Borna disease virus infection in Scottish blood donors

artículo científico publicado en 2004

Ixodes scapularis and Ixodes ricinus tick cell lines respond to infection with tick-borne encephalitis virus: transcriptomic and proteomic analysis

artículo científico publicado en 2015

Knockdown of piRNA pathway proteins results in enhanced Semliki Forest virus production in mosquito cells

artículo científico publicado en 2013

Lyssavirus infection activates interferon gene expression in the brain

artículo científico publicado en 2006

Modelling the within-host dynamics of the foot-and-mouth disease virus in cattle.

artículo científico publicado en 2012

Multiple sclerosis, viruses and glycolipids

artículo científico publicado en 1986

Neurons and oligodendrocytes in the mouse brain differ in their ability to replicate Semliki Forest virus

artículo científico publicado en 2008

Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice

artículo científico publicado en 2013

PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response

artículo científico publicado en 2009

Pathogenesis of Dugbe virus infection in wild-type and interferon-deficient mice

artículo científico publicado en 2006

Pathogenesis of Semliki Forest virus encephalitis

artículo científico publicado en 2002

Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus

artículo científico publicado en 2012

Prime-boost immunization strategies against Chikungunya virus

artículo científico publicado en 2014

Properties of non-structural protein 1 of Semliki Forest virus and its interference with virus replication

artículo científico publicado en 2008

RNA integrity in post mortem human variant Creutzfeldt-Jakob disease (vCJD) and control brain tissue.

artículo científico

Replication of the A7(74) strain of Semliki Forest virus is restricted in neurons

artículo científico publicado en 1993

Semliki Forest virus nonstructural protein 2 is involved in suppression of the type I interferon response

artículo científico publicado en 2007

Semliki Forest virus strongly reduces mosquito host defence signaling

artículo científico publicado en 2008

Semliki forest virus-induced endoplasmic reticulum stress accelerates apoptotic death of mammalian cells

artículo científico publicado en 2010

Superinfection Exclusion in Mosquitoes and Its Potential as an Arbovirus Control Strategy

artículo científico publicado en 2020

The PI capsid region of Theiler's virus controls replication in mouse glial cell cultures

artículo científico publicado en 1997

The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system

artículo científico publicado en 1992

The limited fragmentation of porcine haemolytic immunoglobulin M. Evidence that haemolytic activity depends on the number of Fab arms that can attach to the erythrocyte surface

scientific article published on 01 May 1982

The type I interferon system protects mice from Semliki Forest virus by preventing widespread virus dissemination in extraneural tissues, but does not mediate the restricted replication of avirulent virus in central nervous system neurons

artículo científico publicado en 2007

Tick cell lines for study of Crimean-Congo hemorrhagic fever virus and other arboviruses

artículo científico publicado en 2011

Transneuronal spread of Semliki Forest virus in the developing mouse olfactory system is determined by neuronal maturity

artículo científico publicado en 1998

Virus tropism, distribution, persistence and pathology in the corpus callosum of the Semliki Forest virus-infected mouse brain: a novel system to study virus-oligodendrocyte interactions

artículo científico publicado en 2006

Viruses selectively upregulate Toll-like receptors in the central nervous system

artículo científico publicado en 2005

Lista de obras de John Fazakerley

A new index of agonal state for neurological disease

A single amino acid change in the nuclear localization sequence of the nsP2 protein affects the neurovirulence of Semliki Forest virus

A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication

Ability of the Encephalitic Arbovirus Semliki Forest Virus To Cross the Blood-Brain Barrier Is Determined by the Charge of the E2 Glycoprotein

Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs.

Advances in dissecting mosquito innate immune responses to arbovirus infection

Antiviral RNA interference responses induced by Semliki Forest virus infection of mosquito cells: characterization, origin, and frequency-dependent functions of virus-derived small interfering RNAs

Antiviral responses of arthropod vectors: an update on recent advances

Attenuation of bunyavirus replication by rearrangement of viral coding and noncoding sequences

Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon.

CNS gene therapy applications of the Semliki Forest virus 1 vector are limited by neurotoxicity

Cell-to-Cell Spread of the RNA Interference Response Suppresses Semliki Forest Virus (SFV) Infection of Mosquito Cell Cultures and Cannot Be Antagonized by SFV

Characterization of the cellular and cytokine response in the central nervous system following Semliki Forest virus infection

Coinfection of tick cell lines has variable effects on replication of intracellular bacterial and viral pathogens

Computer analysis suggests a role for signal sequences in processing polyproteins of enveloped RNA viruses and as a mechanism of viral fusion

Cyclosporin, blood-brain barrier, and multiple sclerosis

Cyclosporine enhances virally induced T-cell-mediated demyelination. The effect of cyclosporine on a demyelinating virus infection

Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines

Differences in Processing Determinants of Nonstructural Polyprotein and in the Sequence of Nonstructural Protein 3 Affect Neurovirulence of Semliki Forest Virus

Differential expression of erythroid genes in prion disease.

Following Acute Encephalitis, Semliki Forest Virus is Undetectable in the Brain by Infectivity Assays but Functional Virus RNA Capable of Generating Infectious Virus Persists for Life ⬇️

Gene expression analysis in distinct regions of the central nervous system during the development of SSBP/1 sheep scrapie

Gene expression profiling of the preclinical scrapie-infected hippocampus

Gene silencing in tick cell lines using small interfering or long double-stranded RNA.

Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection ⬇️

Identification of up-regulated genes by array analysis in scrapie-infected mouse brains.

In Semliki Forest virus encephalitis, antibody rapidly clears infectious virus and is required to eliminate viral material from the brain, but is not required to generate lesions of demyelination

In memoriam--Richard M. Elliott (1954-2015)

In response to pathogens, glial cells dynamically and differentially regulate Toll-like receptor gene expression

Inducible cytokine gene expression in the brain in the ME7/CV mouse model of scrapie is highly restricted, is at a strikingly low level relative to the degree of gliosis and occurs only late in disease

Induction and suppression of tick cell antiviral RNAi responses by tick-borne flaviviruses

Innate immune response gene expression profiles of N9 microglia are pathogen-type specific

Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus

Investigation of frequency of active Borna disease virus infection in Scottish blood donors

Ixodes scapularis and Ixodes ricinus tick cell lines respond to infection with tick-borne encephalitis virus: transcriptomic and proteomic analysis

Knockdown of piRNA pathway proteins results in enhanced Semliki Forest virus production in mosquito cells

Lyssavirus infection activates interferon gene expression in the brain

Modelling the within-host dynamics of the foot-and-mouth disease virus in cattle.

Multiple sclerosis, viruses and glycolipids

Neurons and oligodendrocytes in the mouse brain differ in their ability to replicate Semliki Forest virus

Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice

PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response

Pathogenesis of Dugbe virus infection in wild-type and interferon-deficient mice

Pathogenesis of Semliki Forest virus encephalitis

Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus

Prime-boost immunization strategies against Chikungunya virus

Properties of non-structural protein 1 of Semliki Forest virus and its interference with virus replication

RNA integrity in post mortem human variant Creutzfeldt-Jakob disease (vCJD) and control brain tissue.

Replication of the A7(74) strain of Semliki Forest virus is restricted in neurons

Semliki Forest virus nonstructural protein 2 is involved in suppression of the type I interferon response

Semliki Forest virus strongly reduces mosquito host defence signaling

Semliki forest virus-induced endoplasmic reticulum stress accelerates apoptotic death of mammalian cells

Superinfection Exclusion in Mosquitoes and Its Potential as an Arbovirus Control Strategy

The PI capsid region of Theiler's virus controls replication in mouse glial cell cultures

The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system

The limited fragmentation of porcine haemolytic immunoglobulin M. Evidence that haemolytic activity depends on the number of Fab arms that can attach to the erythrocyte surface

The type I interferon system protects mice from Semliki Forest virus by preventing widespread virus dissemination in extraneural tissues, but does not mediate the restricted replication of avirulent virus in central nervous system neurons

Tick cell lines for study of Crimean-Congo hemorrhagic fever virus and other arboviruses

Transneuronal spread of Semliki Forest virus in the developing mouse olfactory system is determined by neuronal maturity

Virus tropism, distribution, persistence and pathology in the corpus callosum of the Semliki Forest virus-infected mouse brain: a novel system to study virus-oligodendrocyte interactions

Viruses selectively upregulate Toll-like receptors in the central nervous system