Lista de obras - Johannes V. Swinnen - Dominio Público Uruguay

5-aminoimidazole-4-carboxamide riboside enhances effect of ionizing radiation in PC3 prostate cancer cells.

artículo científico publicado en 2011

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

artículo científico publicado en 2004

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

artículo científico publicado en 2023

ATP Citrate Lyase Knockdown Induces Growth Arrest and Apoptosis through Different Cell- and Environment-Dependent Mechanisms ⬇️

artículo científico publicado el 20 de junio de 2012

ATP-Citrate Lyase: A Key Player in Cancer Metabolism ⬇️

artículo científico publicado el 10 de julio de 2012

Aberrant activation of fatty acid synthesis suppresses primary cilium formation and distorts tissue development.

artículo científico publicado en 2010

An aged rat model of partial androgen deficiency: prevention of both loss of bone and lean body mass by low-dose androgen replacement

artículo científico publicado en 2000

Androgen activation of the sterol regulatory element-binding protein pathway: Current insights.

artículo científico publicado en 2006

Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA-binding protein in the rat.

artículo científico publicado en 1996

Androgens and spermatogenesis: lessons from transgenic mouse models.

artículo científico publicado en 2010

Androgens and the control of lipid metabolism in human prostate cancer cells.

artículo científico publicado en 1998

Androgens decrease and retinoids increase the expression of insulin-like growth factor-binding protein-3 in LNcaP prostatic adenocarcinoma cells

scientific article published on 01 September 1999

Androgens down-regulate the expression of the human homologue of paternally expressed gene-3 in the prostatic adenocarcinoma cell line LNCaP.

artículo científico publicado en 1999

Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway

artículo científico publicado en 2001

Androgens, lipogenesis and prostate cancer.

artículo científico publicado en 2004

Apparent coactivation due to interference of expression constructs with nuclear receptor expression

artículo científico publicado en 2000

Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment

artículo científico publicado en 2014

Characterization of the human secretory component gene promoter.

artículo científico publicado en 1997

Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells

scientific article published on 01 September 2007

Coactivation of an endogenous progesterone receptor by TIF2 in COS-7 cells

artículo científico publicado en 2002

Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells

artículo científico publicado en 2014

Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy

artículo científico publicado en 2004

Coordinate regulation of lipogenic gene expression by androgens: Evidence for a cascade mechanism involving sterol regulatory element binding proteins ⬇️

artículo científico publicado el 25 de noviembre de 1997

Cytokines derived from activated human mononuclear cells markedly stimulate transferrin secretion by cultured Sertoli cells

artículo científico publicado en 1996

De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation

artículo científico publicado en 2010

Do androgens control the uptake of 18F-FDG, 11C-choline and 11C-acetate in human prostate cancer cell lines?

artículo científico publicado en 2011

E2F activity is biphasically regulated by androgens in LNCaP cells

artículo científico publicado en 2001

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research.

artículo científico publicado en 2017

Early effects of Sertoli cell-selective androgen receptor ablation on testicular gene expression.

artículo científico publicado en 2009

Effects and characterization of paracrine factors produced by human prostate stromal cells in bioassays using rat Sertoli cells, LNCaP tumor cells, and cultured prostate epithelial cells

artículo científico publicado en 2001

Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells

artículo científico publicado en 2003

Evaluation of androgen-induced effects on the uptake of [18F]FDG, [11C]choline and [11C]acetate in an androgen-sensitive and androgen-independent prostate cancer xenograft model ⬇️

artículo científico publicado el 24 de abril de 2013

Expression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cells

artículo científico publicado en 2011

Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.

artículo científico publicado en 2003

Gelatinase A secretion and its control in peritubular and Sertoli cell cultures: effects of hormones, second messengers and inducers of cytokine production

article

Hepatosteatosis in peroxisome deficient liver despite increased β-oxidation capacity and impaired lipogenesis.

artículo científico publicado en 2011

Identification of Diazepam-binding Inhibitor/Acyl-CoA-binding Protein as a Sterol Regulatory Element-binding Protein-responsive Gene ⬇️

artículo científico publicado el 7 de agosto de 1998

Identification of the phosphatidic acid phosphatase type 2a isozyme as an androgen-regulated gene in the human prostatic adenocarcinoma cell line LNCaP

artículo científico publicado en 1998

Increased lipogenesis in cancer cells: new players, novel targets.

artículo científico publicado en 2006

Indirect mechanisms and cascades of androgen action.

artículo científico publicado en 1999

Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity.

artículo científico publicado en 2004

Insulin-Like Growth Factor–Type 1 Receptor Inhibitor NVP-AEW541 Enhances Radiosensitivity of PTEN Wild-Type but Not PTEN-Deficient Human Prostate Cancer Cells ⬇️

artículo científico publicado el 1 de septiembre de 2011

LNCaP prostatic adenocarcinoma cells derived from low and high passage numbers display divergent responses not only to androgens but also to retinoids

scientific article published on 01 August 1997

Lipidomics in drug development.

artículo científico

Lipogenesis and lipolysis: the pathways exploited by the cancer cells to acquire fatty acids

artículo científico publicado en 2013

Lipoprotein lipase links dietary fat to solid tumor cell proliferation.

artículo científico publicado en 2011

Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.

artículo científico publicado en 2006

Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype

artículo científico publicado en 2005

Molecular imaging of prostate cancer

artículo científico publicado en 2009

Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles

artículo científico publicado en 2015

Numeric definition of the clinical performance of the nested reverse transcription-PCR for detection of hematogenous epithelial cells and correction for specific mRNA of non-target cell origin as evaluated for prostate cancer cells

artículo científico publicado en 2003

Organotypic cultures of prepubertal mouse testes: a method to study androgen action in sertoli cells while preserving their natural environment.

artículo científico publicado en 2009

Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer.

artículo científico publicado en 2002

Predicting Clinical Efficacy of Vascular Disrupting Agents in Rodent Models of Primary and Secondary Liver Cancers: An Overview with Imaging-Histopathology Correlation

artículo científico publicado en 2020

Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3.

artículo científico publicado en 2015

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

artículo científico publicado en 2022

Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model

artículo científico publicado en 2006

Remodeling of phospholipid composition in colon cancer cells by 1α,25(OH)2D3 and its analogs.

artículo científico publicado en 2015

Retinoids stimulate lipid synthesis and accumulation in LNCaP prostatic adenocarcinoma cells

scientific article published on 01 December 1997

Role of the androgen receptor in skeletal homeostasis: the androgen-resistant testicular feminized male mouse model

artículo científico publicado en 2004

Selective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal development

artículo científico publicado en 2010

Selective activation of the fatty acid synthesis pathway in human prostate cancer

scientific article published on 01 October 2000

Squalene synthase, a determinant of Raft-associated cholesterol and modulator of cancer cell proliferation.

artículo científico publicado en 2007

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.

artículo científico publicado en 2018

Testosterone prevents orchidectomy-induced bone loss in estrogen receptor-alpha knockout mice

artículo científico publicado en 2001

The Effect of a Sertoli Cell-Selective Knockout of the Androgen Receptor on Testicular Gene Expression in Prepubertal Mice

article

The Transfer of Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma

artículo científico publicado en 2019

The estrogen receptor ligand ICI 182,780 does not impair the bone-sparing effects of testosterone in the young orchidectomized rat model

artículo científico publicado en 2002

The generation and use of recombinant extracellular vesicles as biological reference material

artículo científico publicado en 2019

The retinoblastoma protein-associated transcription repressor RBaK interacts with the androgen receptor and enhances its transcriptional activity.

artículo científico publicado en 2003

Transfection with steroid-responsive reporter constructs shows glucocorticoid rather than androgen responsiveness in cultured Sertoli cells

artículo científico publicado en 2006

Triiodothyronine modulates growth, secretory function and androgen receptor concentration in the prostatic carcinoma cell line LNCaP.

artículo científico publicado en 1995

Unique adenosine 3',5' cyclic monophosphate phosphodiesterase messenger ribonucleic acids in rat spermatogenic cells: evidence for differential gene expression during spermatogenesis

artículo científico publicado en 1992

Lista de obras de Johannes V. Swinnen

5-aminoimidazole-4-carboxamide riboside enhances effect of ionizing radiation in PC3 prostate cancer cells.

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

ATP Citrate Lyase Knockdown Induces Growth Arrest and Apoptosis through Different Cell- and Environment-Dependent Mechanisms ⬇️

ATP-Citrate Lyase: A Key Player in Cancer Metabolism ⬇️

Aberrant activation of fatty acid synthesis suppresses primary cilium formation and distorts tissue development.

An aged rat model of partial androgen deficiency: prevention of both loss of bone and lean body mass by low-dose androgen replacement

Androgen activation of the sterol regulatory element-binding protein pathway: Current insights.

Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA-binding protein in the rat.

Androgens and spermatogenesis: lessons from transgenic mouse models.

Androgens and the control of lipid metabolism in human prostate cancer cells.

Androgens decrease and retinoids increase the expression of insulin-like growth factor-binding protein-3 in LNcaP prostatic adenocarcinoma cells

Androgens down-regulate the expression of the human homologue of paternally expressed gene-3 in the prostatic adenocarcinoma cell line LNCaP.

Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway

Androgens, lipogenesis and prostate cancer.

Apparent coactivation due to interference of expression constructs with nuclear receptor expression

Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment

Characterization of the human secretory component gene promoter.

Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells

Coactivation of an endogenous progesterone receptor by TIF2 in COS-7 cells

Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells

Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy

Coordinate regulation of lipogenic gene expression by androgens: Evidence for a cascade mechanism involving sterol regulatory element binding proteins ⬇️

Cytokines derived from activated human mononuclear cells markedly stimulate transferrin secretion by cultured Sertoli cells

De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation

Do androgens control the uptake of 18F-FDG, 11C-choline and 11C-acetate in human prostate cancer cell lines?

E2F activity is biphasically regulated by androgens in LNCaP cells

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research.

Early effects of Sertoli cell-selective androgen receptor ablation on testicular gene expression.

Effects and characterization of paracrine factors produced by human prostate stromal cells in bioassays using rat Sertoli cells, LNCaP tumor cells, and cultured prostate epithelial cells

Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells

Evaluation of androgen-induced effects on the uptake of [18F]FDG, [11C]choline and [11C]acetate in an androgen-sensitive and androgen-independent prostate cancer xenograft model ⬇️

Expression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cells

Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.

Gelatinase A secretion and its control in peritubular and Sertoli cell cultures: effects of hormones, second messengers and inducers of cytokine production

Hepatosteatosis in peroxisome deficient liver despite increased β-oxidation capacity and impaired lipogenesis.

Identification of Diazepam-binding Inhibitor/Acyl-CoA-binding Protein as a Sterol Regulatory Element-binding Protein-responsive Gene ⬇️

Identification of the phosphatidic acid phosphatase type 2a isozyme as an androgen-regulated gene in the human prostatic adenocarcinoma cell line LNCaP

Increased lipogenesis in cancer cells: new players, novel targets.

Indirect mechanisms and cascades of androgen action.

Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity.

Insulin-Like Growth Factor–Type 1 Receptor Inhibitor NVP-AEW541 Enhances Radiosensitivity of PTEN Wild-Type but Not PTEN-Deficient Human Prostate Cancer Cells ⬇️

LNCaP prostatic adenocarcinoma cells derived from low and high passage numbers display divergent responses not only to androgens but also to retinoids

Lipidomics in drug development.

Lipogenesis and lipolysis: the pathways exploited by the cancer cells to acquire fatty acids

Lipoprotein lipase links dietary fat to solid tumor cell proliferation.

Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.

Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype

Molecular imaging of prostate cancer

Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles

Numeric definition of the clinical performance of the nested reverse transcription-PCR for detection of hematogenous epithelial cells and correction for specific mRNA of non-target cell origin as evaluated for prostate cancer cells

Organotypic cultures of prepubertal mouse testes: a method to study androgen action in sertoli cells while preserving their natural environment.

Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer.

Predicting Clinical Efficacy of Vascular Disrupting Agents in Rodent Models of Primary and Secondary Liver Cancers: An Overview with Imaging-Histopathology Correlation

Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3.

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model

Remodeling of phospholipid composition in colon cancer cells by 1α,25(OH)2D3 and its analogs.

Retinoids stimulate lipid synthesis and accumulation in LNCaP prostatic adenocarcinoma cells

Role of the androgen receptor in skeletal homeostasis: the androgen-resistant testicular feminized male mouse model

Selective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal development

Selective activation of the fatty acid synthesis pathway in human prostate cancer

Squalene synthase, a determinant of Raft-associated cholesterol and modulator of cancer cell proliferation.

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.

Testosterone prevents orchidectomy-induced bone loss in estrogen receptor-alpha knockout mice

The Effect of a Sertoli Cell-Selective Knockout of the Androgen Receptor on Testicular Gene Expression in Prepubertal Mice

The Transfer of Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma

The estrogen receptor ligand ICI 182,780 does not impair the bone-sparing effects of testosterone in the young orchidectomized rat model

The generation and use of recombinant extracellular vesicles as biological reference material

The retinoblastoma protein-associated transcription repressor RBaK interacts with the androgen receptor and enhances its transcriptional activity.

Transfection with steroid-responsive reporter constructs shows glucocorticoid rather than androgen responsiveness in cultured Sertoli cells

Triiodothyronine modulates growth, secretory function and androgen receptor concentration in the prostatic carcinoma cell line LNCaP.

Unique adenosine 3',5' cyclic monophosphate phosphodiesterase messenger ribonucleic acids in rat spermatogenic cells: evidence for differential gene expression during spermatogenesis