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Lista de obras de Diethard Mattanovich

1,3-Propanediol production from glycerol with Lactobacillus diolivorans

artículo científico publicado en 2012

16 years research on lactic acid production with yeast - ready for the market?

scientific article published on January 2010

A gene optimization strategy that enhances production of fully functional P-glycoprotein in Pichia pastoris

artículo científico publicado en 2011

A multi-level study of recombinant Pichia pastoris in different oxygen conditions.

artículo científico publicado en 2010

A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii

artículo científico publicado en 2018

A yeast for all seasons - Is Pichia pastoris a suitable chassis organism for future bioproduction?

artículo científico publicado en 2018

Accurate quantification of the redox-sensitive GSH/GSSG ratios in the yeast Pichia pastoris by HILIC-MS/MS.

artículo científico publicado en 2012

Adaptive laboratory evolution -- principles and applications for biotechnology

artículo científico

Amino-acid sequence comparison of nepovirus coat proteins

artículo científico publicado en 1992

An efficient tool for metabolic pathway construction and gene integration for Aspergillus niger.

artículo científico publicado en 2017

Analysis of the structure-function relationship of the S-layer protein SbsC of Bacillus stearothermophilus ATCC 12980 by producing truncated forms.

artículo científico publicado en 2001

Applications of cell sorting in biotechnology

artículo científico publicado en 2006

Assessing viability and cell-associated product of recombinant protein producing Pichia pastoris with flow cytometry

artículo científico publicado en 2003

Bacterial expression and refolding of human trypsinogen.

artículo científico publicado en 2004

Biochemistry of microbial itaconic acid production

artículo científico publicado en 2013

Biomarkers allow detection of nutrient limitations and respective supplementation for elimination in Pichia pastoris fed-batch cultures.

artículo científico publicado en 2017

Biosynthesis of vitamin C by yeast leads to increased stress resistance

artículo científico publicado en 2007

CRISPR/Cas9-Mediated Homology-Directed Genome Editing in Pichia pastoris

scientific article published on 01 January 2019

Characterization of methanol utilization negative Pichia pastoris for secreted protein production: New cultivation strategies for current and future applications

artículo científico publicado en 2020

Characterizing MttA as a mitochondrial cis-aconitic acid transporter by metabolic engineering

artículo científico publicado en 2016

Cloning, disruption and protein secretory phenotype of the GAS1 homologue of Pichia pastoris.

artículo científico publicado en 2006

Coat protein mediated resistance to Plum Pox Virus in Nicotiana clevelandii and N. benthamiana

artículo científico publicado en 1992

Complete genome sequence and transcriptome regulation of the pentose utilizing yeast Sugiyamaella lignohabitans.

artículo científico publicado en 2016

Corrigendum: Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

artículo científico publicado en 2016

Creation of stable heterothallic strains of Komagataella phaffii enables dissection of mating gene regulation.

artículo científico publicado en 2017

Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function.

artículo científico publicado en 2016

Detection and Elimination of Cellular Bottlenecks in Protein-Producing Yeasts

scientific article published on 01 January 2019

Detection of the trans activity of the plum pox virus NIa-like protease in infected plants

artículo científico publicado en 1990

Directed gene copy number amplification in Pichia pastoris by vector integration into the ribosomal DNA locus.

artículo científico publicado en 2009

Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous carboxylesterase only in protease deficient Pichia pastoris.

artículo científico publicado en 2017

Disruption of vacuolar protein sorting components of the HOPS complex leads to enhanced secretion of recombinant proteins in Pichia pastoris

scientific article published on 03 July 2019

Divergent genetic control of protein solubility and conformational quality in Escherichia coli

artículo científico publicado en 2007

Downscaling screening cultures in a multifunctional bioreactor array-on-a-chip for speeding up optimization of yeast-based lactic acid bioproduction

scientific article published on 19 March 2020

Early screening for anti-plum pox virus monoclonal antibodies with different epitope specificities by means of gold-labelled immunosorbent electron microscopy

artículo científico publicado en 1988

Editorial: metabolic modeling in biotechnology and medical research

artículo científico publicado en 2013

Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line

artículo científico publicado en 2005

Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris

artículo científico publicado en 2004

Engineering of Pichia pastoris for improved production of antibody fragments.

artículo científico publicado en 2006

Engineering of alcohol dehydrogenase 2 hybrid-promoter architectures in Pichia pastoris to enhance recombinant protein expression on ethanol

artículo científico publicado en 2019

Engineering of biotin-prototrophy in Pichia pastoris for robust production processes

artículo científico publicado en 2010

Engineering of bottlenecks in Rhizopus oryzae lipase production in Pichia pastoris using the nitrogen source-regulated FLD1 promoter

scientific article published on 01 September 2009

Engineering of protein folding and secretion-strategies to overcome bottlenecks for efficient production of recombinant proteins

artículo científico

Engineering of the citrate exporter protein enables high citric acid production in Aspergillus niger

scientific article published on 13 December 2018

Enhanced glutathione production by evolutionary engineering of Saccharomyces cerevisiae strains.

artículo científico publicado en 2015

Expression of the plum pox virus coat protein region in Escherichia coli

artículo científico publicado en 1989

Flow Cytometric Analysis of Metabolic Stress Effects Due to Recombinant Plasmids and Proteins in Escherichia coli Production Strains

article

Flow cytometric analysis of bacterial physiology during induction of foreign protein synthesis in recombinant Escherichia coli cells

artículo científico publicado en 1998

Functional inclusion bodies produced in the yeast Pichia pastoris.

artículo científico publicado en 2016

Gas Chromatography-Quadrupole Time-of-Flight Mass Spectrometry-Based Determination of Isotopologue and Tandem Mass Isotopomer Fractions of Primary Metabolites for (13)C-Metabolic Flux Analysis.

artículo científico publicado en 2015

Genetic engineering of Lactobacillus diolivorans.

artículo científico publicado en 2013

Genome sequence of the ruminal bacterium Megasphaera elsdenii

artículo científico

Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris.

artículo científico publicado en 2009

Genome-scale analysis of library sorting (GALibSo): Isolation of secretion enhancing factors for recombinant protein production in Pichia pastoris

artículo científico publicado en 2010

Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production.

artículo científico publicado en 2010

GoldenPiCS: a Golden Gate-derived modular cloning system for applied synthetic biology in the yeast Pichia pastoris

artículo científico publicado en 2017

Heading for an economic industrial upgrading of crude glycerol from biodiesel production to 1,3-propanediol by Lactobacillus diolivorans.

artículo científico publicado en 2013

High level expression of a promising anti-idiotypic antibody fragment vaccine against HIV-1 in Pichia pastoris

article

Hypoxic fed-batch cultivation of Pichia pastoris increases specific and volumetric productivity of recombinant proteins

artículo científico publicado en 2008

Identification and characterization of the Komagataella phaffii mating pheromone genes.

artículo científico publicado en 2018

Identification and deletion of the major secreted protein of Pichia pastoris

artículo científico publicado en 2012

Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation

artículo científico publicado en 2014

Impact of glutathione metabolism on zinc homeostasis in Saccharomyces cerevisiae.

artículo científico publicado en 2017

Implications of evolutionary engineering for growth and recombinant protein production in methanol-based growth media in the yeast Pichia pastoris.

artículo científico publicado en 2017

Improvement of lactic acid production in Saccharomyces cerevisiae by cell sorting for high intracellular pH.

artículo científico publicado en 2006

In Pichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response.

artículo científico publicado en 2014

Increased dosage of AOX1 promoter-regulated expression cassettes leads to transcription attenuation of the methanol metabolism in Pichia pastoris

artículo científico publicado en 2017

Increasing pentose phosphate pathway flux enhances recombinant protein production in Pichia pastoris.

scientific article published on 28 March 2016

Induction and measurement of UPR and osmotic stress in the yeast Pichia pastoris.

artículo científico publicado en 2011

Induction without methanol: novel regulated promoters enable high-level expression in Pichia pastoris.

artículo científico publicado en 2013

Influence of growth temperature on the production of antibody Fab fragments in different microbes: a host comparative analysis.

artículo científico publicado en 2010

Integrative Analysis of -Omics Data: A Method Comparison

artículo científico publicado en 2013

Interlaboratory comparison for quantitative primary metabolite profiling in Pichia pastoris

artículo científico publicado en 2013

Intracellular interactome of secreted antibody Fab fragment in Pichia pastoris reveals its routes of secretion and degradation

artículo científico publicado en 2012

Intracellular pH distribution in Saccharomyces cerevisiae cell populations, analyzed by flow cytometry

artículo científico publicado en 2005

Kinetics studies for the optimization of recombinant protein formation.

artículo científico publicado en 1996

Komagataella phaffii YPS1-5 encodes the alpha-factor degrading protease Bar1

scientific article published on 06 May 2020

Lactate production yield from engineered yeasts is dependent from the host background, the lactate dehydrogenase source and the lactate export.

artículo científico publicado en 2006

Macromolecular and elemental composition analysis and extracellular metabolite balances of Pichia pastoris growing at different oxygen levels.

artículo científico publicado en 2009

Mass spectrometry based analysis of nucleotides, nucleosides, and nucleobases--application to feed supplements

artículo científico publicado en 2012

Measurement uncertainty of isotopologue fractions in fluxomics determined via mass spectrometry.

artículo científico publicado en 2013

Metabolic engineering of Pichia pastoris.

artículo científico publicado en 2018

Metabolic profiling of amino acids in cellular samples via zwitterionic sub-2 μm particle size HILIC-MS/MS and a uniformly 13C labeled internal standard.

artículo científico publicado en 2013

Metabolomics integrated elementary flux mode analysis in large metabolic networks.

artículo científico publicado en 2015

Metabolomics of Pichia pastoris: impact of buffering conditions on the kinetics and nature of metabolite loss during quenching

artículo científico publicado en 2017

Metabolomics sampling of Pichia pastoris revisited: rapid filtration prevents metabolite loss during quenching.

artículo científico publicado en 2015

Methanol regulated yeast promoters: production vehicles and toolbox for synthetic biology.

artículo científico publicado en 2015

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

artículo científico publicado en 2015

Microbe Profile: Komagataella phaffii: a methanol devouring biotech yeast formerly known as Pichia pastoris

artículo científico publicado en 2020

Microbial organic acid production as carbon dioxide sink

artículo científico publicado en 2017

Microbial production of 1,3-propanediol.

scientific article published on January 2008

Microbial production of organic acids: expanding the markets.

artículo científico publicado en 2008

Microscale Perfusion-based Cultivation for Pichia pastoris Clone Screening Enables Accelerated and Optimized Recombinant Protein Production Processes

scientific article published on 15 September 2020

Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production

artículo científico publicado en 2014

Modeling and measuring intracellular fluxes of secreted recombinant protein in Pichia pastoris with a novel 34S labeling procedure ⬇️

artículo científico publicado el 26 de junio de 2011

Monitoring intracellular redox conditions in the endoplasmic reticulum of living yeasts

artículo científico publicado en 2010

Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions

artículo científico publicado en 2007

Multistep processing of the secretion leader of the extracellular protein Epx1 in Pichia pastoris and implications for protein localization.

artículo científico publicado en 2015

Non-genetic impact factors on chronological lifespan and stress resistance of baker's yeast

artículo científico publicado en 2016

Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays.

artículo científico publicado en 2008

Old obstacles and new horizons for microbial chemical production

artículo científico

Open access to sequence: browsing the Pichia pastoris genome

artículo científico publicado en 2009

Optimization of recombinant gene expression in Escherichia coli.

artículo científico publicado en 1996

Optimization of recombinant protein expression level in Escherichia coli by flow cytometry and cell sorting

artículo científico publicado en 2002

Organic acids from lignocellulose: Candida lignohabitans as a new microbial cell factory.

artículo científico publicado en 2015

Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion.

artículo científico publicado en 2014

Oxidative protein folding and unfolded protein response elicit differing redox regulation in endoplasmic reticulum and cytosol of yeast.

artículo científico publicado en 2012

Pichia pastoris Aft1--a novel transcription factor, enhancing recombinant protein secretion

artículo científico publicado en 2014

Pichia pastoris Exhibits High Viability and a Low Maintenance Energy Requirement at Near-Zero Specific Growth Rates.

scientific article published on 20 May 2016

Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level.

artículo científico publicado en 2015

Pichia pastoris secretes recombinant proteins less efficiently than Chinese hamster ovary cells but allows higher space-time yields for less complex proteins

artículo científico publicado en 2014

Production of recombinant proteins and metabolites in yeasts: when are these systems better than bacterial production systems?

artículo científico publicado en 2010

Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview

artículo científico publicado en 2008

Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris ⬇️

artículo científico publicado el 3 de noviembre de 2011

Quo vadis? The challenges of recombinant protein folding and secretion in Pichia pastoris

artículo científico publicado en 2015

Recombinant expression of alliin lyase from garlic (Allium sativum) in bacteria and yeasts

artículo científico publicado en 1998

Recombinant protein production 6 (Vienna, February 2011).

artículo científico publicado en 2011

Recombinant protein production 6: a comparative view on host physiology

scientific article published on 13 October 2011

Recombinant protein production in the new Millennium

artículo científico publicado en 2007

Recombinant protein production in yeasts

artículo científico publicado en 2005

Recombinant protein production in yeasts

scientific article published on 01 January 2012

Recombinant protein production in yeasts.

artículo científico publicado en 2004

Regeneration of transgenic plants of Prunus armeniaca containing the coat protein gene of Plum Pox Virus

artículo científico publicado en 1992

Reverse engineering of protein secretion by uncoupling of cell cycle phases from growth

artículo científico publicado en 2011

S-layer gene sbsC of Bacillus stearothermophilus ATCC 12980: molecular characterization and heterologous expression in Escherichia coli

artículo científico publicado en 2000

Sample preparation workflow for the liquid chromatography tandem mass spectrometry based analysis of nicotinamide adenine dinucleotide phosphate cofactors in yeast

artículo científico publicado en 2014

Six novel constitutive promoters for metabolic engineering of Aspergillus niger

artículo científico publicado en 2012

Stopping the DNA polymerase activity at a specific site with a dideoxyoligonucleotide: selective labelling of single stranded circular DNA

artículo científico publicado en 1989

Stress in recombinant protein producing yeasts.

artículo científico publicado en 2004

Superior protein titers in half the fermentation time: Promoter and process engineering for the glucose-regulated GTH1 promoter of Pichia pastoris

artículo científico publicado en 2018

Systems biotechnology for protein production in Pichia pastoris.

artículo científico publicado en 2017

Systems metabolic engineering, industrial biotechnology and microbial cell factories

artículo científico publicado en 2012

Systems-level organization of yeast methylotrophic lifestyle.

artículo científico publicado en 2015

Targeting enzymes to the right compartment: metabolic engineering for itaconic acid production by Aspergillus niger.

artículo científico publicado en 2013

The Degree and Length of O-glycosylation of Recombinant Proteins Produced in Pichia Pastoris Depends on the Nature of the Protein and the Process Type

scientific article published on 25 September 2020

The bud tip is the cellular hot spot of protein secretion in yeasts

artículo científico publicado en 2016

The effect of temperature on the proteome of recombinant Pichia pastoris

artículo científico publicado en 2009

The impact of ERAD on recombinant protein secretion in Pichia pastoris (syn Komagataella spp.).

artículo científico publicado en 2018

The impact of oxygen on the transcriptome of recombinant S. cerevisiae and P. pastoris - a comparative analysis.

artículo científico publicado en 2011

The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO2

artículo científico publicado en 2019

The lipidome and proteome of microsomes from the methylotrophic yeast Pichia pastoris

artículo científico publicado en 2014

The metabolic growth limitations of petite cells lacking the mitochondrial genome

artículo científico publicado en 2021

The response to unfolded protein is involved in osmotolerance of Pichia pastoris.

artículo científico publicado en 2010

The scientific impact of microbial cell factories.

artículo científico publicado en 2008

The secretome of Pichia pastoris in fed-batch cultivations is largely independent of the carbon source but changes quantitatively over cultivation time

artículo científico publicado en 2019

The vitamin-sensitive promoter PTHI11 enables pre-defined autonomous induction of recombinant protein production in Pichia pastoris.

artículo científico publicado en 2016

Transcriptional engineering of the glyceraldehyde-3-phosphate dehydrogenase promoter for improved heterologous protein production in Pichia pastoris.

artículo científico publicado en 2017

Transcriptomics-based identification of novel factors enhancing heterologous protein secretion in yeasts.

artículo científico publicado en 2007

U13C cell extract of Pichia pastoris--a powerful tool for evaluation of sample preparation in metabolomics

scientific article published on 22 October 2012

Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics.

artículo científico

Versatile modeling and optimization of fed batch processes for the production of secreted heterologous proteins with Pichia pastoris

artículo científico publicado en 2006

Yeast biotechnology: teaching the old dog new tricks.

artículo científico publicado en 2014

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