Filtros de búsqueda

Lista de obras de Marc Foretz

5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

artículo científico publicado en 2006

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

artículo científico publicado en 2006

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo

artículo científico publicado en 2014

A functional role for AMPK in female fertility and endometrial regeneration

scientific article published on 01 December 2018

A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy

scientific article published on 03 October 2006

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators.

artículo científico publicado en 2014

AMP-activated Protein Kinase As a Target For Pathogens: Friends Or Foes?

scientific article published on 16 April 2015

AMP-activated Protein Kinase Deficiency Blocks the Hypoxic Ventilatory Response and Thus Precipitates Hypoventilation and Apnea.

artículo científico publicado en 2015

AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.

artículo científico publicado en 2009

AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes

artículo científico publicado en 1998

AMP-activated protein kinase inhibits transforming growth factor-beta-induced Smad3-dependent transcription and myofibroblast transdifferentiation.

artículo científico publicado en 2008

AMP-activated protein kinase mediates myogenin expression and myogenesis via histone deacetylase 5

scientific journal article

AMP-activated protein kinase phosphorylates R5/PTG, the glycogen targeting subunit of the R5/PTG-protein phosphatase 1 holoenzyme, and accelerates its down-regulation by the laforin-malin complex

artículo científico publicado en 2009

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase.

artículo científico publicado en 2012

AMP-activated protein kinase suppresses matrix metalloproteinase-9 expression in mouse embryonic fibroblasts

artículo científico publicado en 2011

AMP-activated protein kinase α1 but not α2 catalytic subunit potentiates myogenin expression and myogenesis

scientific article published on 16 September 2013

AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol

artículo científico publicado en 2009

AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside

artículo científico publicado en 2007

AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

artículo científico publicado en 2019

AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo

scholarly article by Marc Foretz published in September 2018

AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development.

artículo científico publicado en 2018

AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs

artículo científico publicado en 2015

AMPK activation by oncogenesis is required to maintain cancer cell proliferation in astrocytic tumors

artículo científico publicado en 2013

AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes

artículo científico publicado en 2013

AMPK and TBC1D1 Regulate Muscle Glucose Uptake After - But Not During - Exercise and Contraction

scientific article published on 22 April 2019

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B.

artículo científico publicado en 2016

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity

scientific article published on 20 March 2014

AMPK in skeletal muscle function and metabolism.

artículo científico publicado en 2017

AMPK inhibition in health and disease

artículo científico publicado en 2010

AMPK is not required for the effect of metformin on the inhibition of BMP6-induced hepcidin gene expression in hepatocytes.

artículo científico publicado en 2017

AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR

scientific article published on 19 August 2019

AMPK regulates circadian rhythms in a tissue- and isoform-specific manner

artículo científico publicado en 2011

AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis

artículo científico publicado en 2016

AMPK: Lessons from transgenic and knockout animals

artículo científico publicado en 2009

AMPKα is essential for acute exercise-induced gene responses but not for exercise training-induced adaptations in mouse skeletal muscle.

artículo científico publicado en 2015

AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression

artículo científico publicado en 2013

AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration

artículo científico publicado en 2013

AMPKα1-LDH pathway regulates muscle stem cell self-renewal by controlling metabolic homeostasis.

artículo científico publicado en 2017

AMPKα1: a glucose sensor that controls CD8 T-cell memory

artículo científico publicado en 2013

Abnormal metabolism flexibility in response to high palmitate concentrations in myotubes derived from obese type 2 diabetic patients

artículo científico publicado en 2010

Activation of 5'-AMP-activated kinase with diabetes drug metformin induces casein kinase Iepsilon (CKIepsilon)-dependent degradation of clock protein mPer2.

artículo científico publicado en 2007

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

artículo científico publicado en 2006

Activation of AMPK for a Break in Hepatic Lipid Accumulation and Circulating Cholesterol.

artículo científico publicado en 2018

Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.

artículo científico publicado en 2015

Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice.

artículo científico publicado en 2017

Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells

artículo científico publicado en 2014

Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling

artículo científico publicado en 2011

Animal Models to Study AMPK.

artículo científico publicado en 2016

Antagonistic control of muscle cell size by AMPK and mTORC1.

artículo científico publicado en 2011

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

artículo científico publicado en 2016

Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

scientific article published on 30 August 2016

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

artículo científico publicado en 2013

Borrelia burgdorferi Sensu Stricto, a Bacterial Species "Made in the U.S.A."?

artículo científico publicado el 1 de octubre de 1997

Bypassing AMPK Phosphorylation

artículo científico publicado en 2014

Cellular and molecular mechanisms of metformin: an overview

artículo científico publicado en 2012

Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates

artículo científico publicado en 2019

Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

artículo científico publicado en 2015

Connection between cardiac vascular permeability, myocardial edema, and inflammation during sepsis: role of the α1AMP-activated protein kinase isoform

artículo científico publicado en 2013

Coordinated maintenance of muscle cell size control by AMP-activated protein kinase

artículo científico publicado en 2010

Correction: Liver AMP-Activated Protein Kinase Is Unnecessary for Gluconeogenesis but Protects Energy State during Nutrient Deprivation

artículo científico publicado en 2017

Corrigendum: SIKs control osteocyte responses to parathyroid hormone

artículo científico publicado en 2017

Endospanin1 affects oppositely body weight regulation and glucose homeostasis by differentially regulating central leptin signaling

artículo científico publicado en 2016

Endothelial α1AMPK modulates angiotensin II-mediated vascular inflammation and dysfunction

artículo científico publicado en 2019

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK.

artículo científico publicado en 2016

Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding

artículo científico publicado en 2006

Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle

scientific article published on 25 July 2018

Expanding roles for AMPK in skeletal muscle plasticity

artículo científico

Expression of Uncoupling Protein 3 and GLUT4 Gene in Skeletal Muscle of Preterm Newborns: Possible Control by AMP-Activated Protein Kinase

article

Finely-tuned regulation of AMP-activated protein kinase (AMPK) is crucial for human adult erythropoiesis

artículo científico publicado en 2018

From cancer to diabetes treatment : the tumor suppressor LKB1 as a new pharmacological target

artículo científico publicado en 2006

Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk

artículo científico publicado en 2016

Glucose availability but not changes in pancreatic hormones sensitizes hepatic AMPK activity during nutritional transition in rodents

artículo científico publicado en 2020

Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons

artículo científico publicado en 2010

Haptoglobin is degraded by iron in C57BL/6 mice: a possible link with endoplasmic reticulum stress

artículo científico publicado en 2007

Hepatic glucose sensing is required to preserve β cell glucose competence

artículo científico publicado en 2013

Hepatic peroxisome proliferator-activated receptor γ coactivator 1α and hepcidin are coregulated in fasted/refed states in mice

artículo científico publicado en 2012

IL-15 improves skeletal muscle oxidative metabolism and glucose uptake in association with increased respiratory chain supercomplex formation and AMPK pathway activation

artículo científico publicado en 2018

Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype

scientific journal article

Important role for AMPKalpha1 in limiting skeletal muscle cell hypertrophy

artículo científico publicado en 2009

Inactivation of AMPKα1 induces asthenozoospermia and alters spermatozoa morphology

artículo científico publicado en 2012

Increased FAT/CD36 cycling and lipid accumulation in myotubes derived from obese type 2 diabetic patients

artículo científico publicado en 2011

Inhibition of mitochondrial complex 1 by the S6K1 inhibitor PF-4708671 partly contributes to its glucose metabolic effects in muscle and liver cells

artículo científico publicado en 2019

Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.

artículo científico publicado en 2000

Intestinal Epithelial AMPK Deficiency Causes Delayed Colonic Epithelial Repair in DSS-Induced Colitis

artículo científico publicado en 2022

Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice

artículo científico publicado en 2008

Intramyocellular lipid accumulation is associated with permanent relocation ex vivo and in vitro of fatty acid translocase (FAT)/CD36 in obese patients

artículo científico publicado en 2010

Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

artículo científico publicado en 2016

LKB1 and AMPK regulate synaptic remodeling in old age

artículo científico publicado en 2014

LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia

artículo científico publicado en 2015

Leishmania infantum modulates host macrophage mitochondrial metabolism by hijacking the SIRT1-AMPK axis

artículo científico publicado en 2015

Lipoprotein internalisation induced by oncogenic AMPK activation is essential to maintain glioblastoma cell growth

artículo científico publicado en 2014

Liver AMP-Activated Protein Kinase Is Unnecessary for Gluconeogenesis but Protects Energy State during Nutrient Deprivation

artículo científico publicado en 2017

Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin

artículo científico publicado en 2006

Lkb1 suppresses amino acid-driven gluconeogenesis in the liver

artículo científico publicado en 2020

Loss of hepatic AMP-activated protein kinase impedes the rate of glycogenolysis but not gluconeogenic fluxes in exercising mice

artículo científico publicado en 2017

Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3

scientific journal article

Maintenance of red blood cell integrity by AMP-activated protein kinase alpha1 catalytic subunit

artículo científico publicado en 2010

Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

artículo científico publicado en 2007

Mechanism of action of compound-13: an α1-selective small molecule activator of AMPK

artículo científico publicado en 2014

Mechanism of inhibition of hepatic glucose production by metformin: a new concept for an old remedy

artículo científico publicado en 2010

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR

artículo científico publicado en 2019

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR

artículo científico publicado en 2019

Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status

artículo científico publicado en 2011

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

artículo científico publicado en 2010

Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation

scientific article published on 23 January 2020

Metformin: from mechanisms of action to therapies

artículo científico publicado en 2014

Mitochondrial fission and remodelling contributes to muscle atrophy.

artículo científico publicado en 2010

Modifying the Dietary Carbohydrate-to-Protein Ratio Alters the Postprandial Macronutrient Oxidation Pattern in Liver of AMPK-Deficient Mice

artículo científico publicado en 2017

Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate

artículo científico publicado en 2015

Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice

scientific article published on 25 September 2020

Myeloid-Restricted AMPKα1 Promotes Host Immunity and Protects against IL-12/23p40-Dependent Lung Injury during Hookworm Infection.

artículo científico publicado en 2016

Nervous glucose sensing regulates postnatal β cell proliferation and glucose homeostasis

artículo científico publicado en 2013

New promises for metformin: advances in the understanding of its mechanisms of action

artículo científico publicado en 2014

Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK.

artículo científico publicado en 2015

Overexpression of AMP-activated protein kinase or protein kinase D prevents lipid-induced insulin resistance in cardiomyocytes

artículo científico publicado en 2012

PPARγ contributes to PKM2 and HK2 expression in fatty liver

artículo científico publicado en 2012

PRKAA1/AMPKα1 is required for autophagy-dependent mitochondrial clearance during erythrocyte maturation

artículo científico publicado en 2014

Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain

artículo científico publicado en 2006

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

article

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

artículo científico publicado en 2013

Polyunsaturated fatty acids inhibit fatty acid synthase and spot-14-protein gene expression in cultured rat hepatocytes by a peroxidative mechanism.

artículo científico publicado en 1999

Proglucagon Promoter Cre-Mediated AMPK Deletion in Mice Increases Circulating GLP-1 Levels and Oral Glucose Tolerance.

artículo científico publicado en 2016

Regulation of hepatic metabolism by AMPK

artículo científico publicado el 14 de octubre de 2010

Revisiting the mechanisms of metformin action in the liver

artículo científico

Régulation du métabolisme énergétique par l’AMPK

artículo científico publicado en 2006

S6 kinase deletion suppresses muscle growth adaptations to nutrient availability by activating AMP kinase

artículo científico publicado en 2007

SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes

artículo científico publicado en 2015

SIKs control osteocyte responses to parathyroid hormone

artículo científico publicado en 2016

Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential

scientific article published on 24 August 2018

Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential: (Trends Endocrinol. Metab. 29, 723-735, 2018)

artículo científico publicado en 2019

Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling

scientific article published on 01 December 2019

Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver

artículo científico publicado en 2005

Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality.

artículo científico publicado en 2016

Specific deletion of AMP-activated protein kinase (α1AMPK) in murine oocytes alters junctional protein expression and mitochondrial physiology

artículo científico publicado en 2015

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

artículo científico publicado en 1999

Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription

article

Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver

artículo científico publicado en 2006

TIM-4 glycoprotein-mediated degradation of dying tumor cells by autophagy leads to reduced antigen presentation and increased immune tolerance

artículo científico publicado en 2013

Targeting AMP-activated protein kinase as a novel therapeutic approach for the treatment of metabolic disorders.

artículo científico publicado en 2007

The AMPK-SIRT signaling network regulates glucose tolerance under calorie restriction conditions.

artículo científico publicado en 2014

The AMPKγ1 subunit plays an essential role in erythrocyte membrane elasticity, and its genetic inactivation induces splenomegaly and anemia.

artículo científico publicado en 2010

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver

artículo científico publicado en 2014

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

artículo científico publicado en 2010

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

artículo científico publicado en 2015

The inhibitory effect of glucose on phosphoenolpyruvate carboxykinase gene expression in cultured hepatocytes is transcriptional and requires glucose metabolism

artículo científico publicado en 1999

The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer

artículo científico publicado en 2020

Therapy: Metformin takes a new route to clinical efficacy

artículo científico publicado en 2015

Transcriptional block of AMPK-induced autophagy promotes glutamate excitotoxicity in nutrient-deprived SH-SY5Y neuroblastoma cells

scientific article published on 12 November 2019

Transgenic Mice Expressing Human Proteinase 3 Exhibit Sustained Neutrophil-Associated Peritonitis.

artículo científico publicado en 2017

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

artículo científico publicado en 2019

[« Self-eating » to survive - coordinated regulation of autophagy by nutrients].

artículo científico publicado en 2011

α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation

artículo científico publicado en 2011

α1AMPK deletion in myelomonocytic cells induces a pro-inflammatory phenotype and enhances angiotensin II-induced vascular dysfunction

artículo científico publicado en 2018